5,808 research outputs found

    S98RS SGR No. 16 (Online Site)

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    A RESOLUTION To recommend to the University Administration and the Office of Computing Services that LSU provide an online, central registration and information site to serve students as the authoritative, primary conduit of campus news, applications, and feedback

    A component-based middleware framework for configurable and reconfigurable Grid computing

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    Significant progress has been made in the design and development of Grid middleware which, in its present form, is founded on Web services technologies. However, we argue that present-day Grid middleware is severely limited in supporting projected next-generation applications which will involve pervasive and heterogeneous networked infrastructures, and advanced services such as collaborative distributed visualization. In this paper we discuss a new Grid middleware framework that features (i) support for advanced network services based on the novel concept of pluggable overlay networks, (ii) an architectural framework for constructing bespoke Grid middleware platforms in terms of 'middleware domains' such as extensible interaction types and resource discovery. We believe that such features will become increasingly essential with the emergence of next-generation e-Science applications. Copyright (c) 2005 John Wiley & Sons, Ltd

    Mathematical Modelling of Chemical Diffusion through Skin using Grid-based PSEs

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    A Problem Solving Environment (PSE) with connections to remote distributed Grid processes is developed. The Grid simulation is itself a parallel process and allows steering of individual or multiple runs of the core computation of chemical diffusion through the stratum corneum, the outer layer of the skin. The effectiveness of this Grid-based approach in improving the quality of the simulation is assessed

    Comparison of the 2005 growth charts for Saudi children and adolescents to the 2000 CDC growth charts

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    Background and objectives: The 2000 CDC growth charts for the United States, a revision of the National Center for Health Statistics/World Health Organization (NCHS/WHO) growth charts, were released in 2002 to replace the NCHS/WHO charts. We evaluated the differences between the CDC growth charts and the Saudi 2005 reference to determine the implications of using the 2000 CDC growth charts in Saudi children and adolescents. Subjects and methods: The Saudi reference was based on a cross-sectional representative sample of the Saudi population of healthy children and adolescents from birth to 19 years of age. Measurements of the length/ stature, weight and head circumference were performed according to expert recommendations. The CDC charts from birth to 20 years were based on a cross-sectional representative national sample from five sources collected between 1963 and 1994. The data from the CDC study including the 3rd, 5th, 50th, 95th, and 97th percentiles were plotted against the corresponding percentiles on the Saudi charts for the weight for age, height for age, weight for height for children from 0 to 36 months and weight for age, stature for age and body mass index for children 2 to 19 years of age. Results: There were major differences between the two growth charts. The main findings were the upward shift of the lower percentiles of the CDC curves and the overlap or downward shift of the upper percentiles, especially for weight, weight for height, and BMI. Conclusions: The use of the 2000 CDC growth charts for Saudi children and adolescents increases the prevalence of undernutrition, stunting, and wasting, potentially leading to unnecessary referrals, investigations and parental anxiety. The increased prevalence of overweight and obesity is alarming and needs further investigation

    S98RS SGR No. 13 (Admissons Standard)

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    A RESOLUTION To encourage the University Administration, the Office of Admissions, the Office of Academic Affairs, and the LSU A & M faculty to create a more stringent, uniform standard of admission for entering students

    After 15 March: Responses to the White-Supremacist Terrorist Attacks

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    For many of us who do not encounter forms of racial and religious hatred in daily life, the white-supremacist terrorist attacks of 15 March, which killed 51 people and injured 49 others at the Al-Noor mosque and Linwood Islamic Centre in Christchurch, were experienced as a traumatic blow seemingly from nowhere. Explaining and politically responding to the tragedy felt imperative, but collective grief, indignation, and empathy were quite rightly the most immediate feelings and responses in the weeks that followed. Here, writing from a Pākehā, non-Muslim perspective, we want to consider some of the wider explanatory and strategic questions that the Left must face in the wake of these attacks. &nbsp

    The Role of Equine Herpesvirus Type 4 Glycoprotein K in Virus Replication

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    Equine herpesvirus 4 (EHV-4) is an important equine pathogen that causes respiratory tract disease among horses worldwide. Glycoprotein K (gK) homologues have been identified in several alphaherpesviruses as a major player in virus entry, replication, and spread. In the present study, EHV-4 gK-deletion mutant has been generated by using bacterial artificial chromosome technology and Red mutagenesis to investigate the role of gK in EHV-4 replication. Our findings reported here show that gK is essential for virus replication <em>in vitro</em> and that the gK-negative strain was not able to be reconstituted in equine cells. It is noteworthy that these findings agree with the previously published study describing gK deletion in other alphaherpesviruses

    Successful business intelligence implementation: a systematic literature review

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    Purpose: The purpose of this paper is to present a systematic literature review to determine the factors that relate to successful Business Intelligence (BI) system implementation. Design/methodology/approach: The study has a collecting of literature that highlights potential references in relation to factors for system implementation in relation to BI. There is the employment of ‘content analysis’ given that the study purpose is the achievement of deep understanding of the variety of factors of implementation that other researchers have previously identified. Findings: An initial investigation of 38 empirical studies on the implementation of BI led to 10 factors being compiled. Difficulties in implementation were found to exist in relation to the operationalisation of large numbers of factors within organisations. The implementation factors were analysed and then sorted into descending order based upon their frequency of occurrence. Research limitations/implications: The research is limited to consider BI implementation factors. Moreover, Literature is collected from selected databases and journals from 1998 to 2018. Practical implications: Researchers of BI may, within the future, develop models for the measurement of the implementation level of BI within industries along with the sustaining of them. Moreover, work-based learning industries can benefit by adopting the results of this study for the effective implementation of BI. The implementation factors can be seen as key constructs upon which there may be the undertaking of more statistical analyses. Originality/value: The original output from this research can help researchers’ in the future in enhancing identification of studies that are relevant for the review of literature for their research. Keywords: Business intelligence, Critical success factor (CSF), Literature review, Implementatio

    Preface: proceedings of the 13th IASWS international conference

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    This short article forms the preface to the Proceedings of the 13th IASWS conference held in Grahamstown in July 2014. It provides a background to the conference, a synthesis of the 15 published papers published in the special issue of JSS and a poem - written and read by Harry Owen on the opening night of the conference

    Enhanced chondrogenic potential in GelMA-based 3D cartilage model via Wnt3a surface immobilization

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    Cartilage tissue engineering aims to develop functional substitutes for treating cartilage defects and osteoarthritis. Traditional two-dimensional (2D) cell culture systems lack the complexity of native cartilage, leading to the development of 3D regenerative cartilage models. In this study, we developed a 3D model using Gelatin Methacryloyl (GelMA)-based hydrogels seeded with Y201 cells, a bone marrow mesenchymal stem cell line. The model investigated chondrogenic differentiation potential in response to Wnt3a stimulation within the GelMA scaffold and validated using known chondrogenic agonists. Y201 cells demonstrated suitability for the model, with increased proteoglycan content and upregulated chondrogenic marker expression under chondrogenic conditions. Wnt3a enhanced cell proliferation, indicating activation of the Wnt/β-catenin pathway, which plays a role in cartilage development. GelMA hydrogels provided an optimal scaffold, supporting cell viability and proliferation. The 3D model exhibited consistent responses to chondrogenic agonists, with TGF-β3 enhancing cartilage-specific extracellular matrix (ECM) production and chondrogenic differentiation. The combination of Wnt3a and TGF-β3 showed synergistic effects, promoting chondrogenic differentiation and ECM production. This study presents a 3D regenerative cartilage model with potential for investigating cartilage biology, disease mechanisms, and drug screening. The model provides insights into complex cartilage regeneration mechanisms and offers a platform for developing therapeutic approaches for cartilage repair and osteoarthritis treatment
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