153 research outputs found
Implant decontamination during surgical peri-implantitis treatment:a randomized, double-blind, placebo-controlled trial
High prevalence of heavy menstrual bleeding in women with rare bleeding disorders in the Netherlands:retrospective data from the RBiN study
Background: Heavy menstrual bleeding (HMB) is associated with a reduced quality of life and limitations in social and physical functioning. Data on HMB in women with rare bleeding disorders (RBDs), including coagulation factor deficiencies and fibrinolytic disorders, are scarce. Objectives: To analyze the prevalence, severity, and treatment of HMB in Dutch women with an RBD. Methods:The Rare Bleeding Disorders in the Netherlands (RBiN) study included 263 patients with an RBD from all 6 hemophilia treatment centers (October 2017-November 2019). In this analysis, data of 111 women aged ≥16 years were studied. According to the International Society on Thrombosis and Haemostasis bleeding assessment tool, HMB symptoms were scored from 0 (no/trivial) to 4 (severe symptoms requiring medical intervention). HMB was defined as a score ≥1. Age at RBD diagnosis was extracted from patient files. Results: HMB was reported by 80% of women (89/111) and was more prevalent in women with a fibrinolytic disorder (33/35; 94%) than in women with a coagulation factor deficiency (56/76; 74%) (P = .011). Of the 89 women with HMB, 82% (n = 73) ever required treatment. Multiple treatment modalities were frequently used, both in severe and mild deficiencies. Hormonal treatment was mostly used (n = 64; 88%), while antifibrinolytics were prescribed less frequently (n = 18; 25%). In women with HMB since menarche (n = 61; 69%), median age at RBD diagnosis was 28 years (IQR, 14-41).Conclusion: HMB is common in women with RBDs. Women with mild deficiencies also frequently reported HMB. Only a minority of women were treated with hemostatic agents. A significant diagnostic delay was observed after the onset of HMB symptoms.</p
Wetenschappers en veldwerkers in Gelderland bespreken gevolgen klimaatverandering
Waterschappen, provincies, waterbedrijven en andere partijen werken vaak samen aan ruimtelijke plannen voor de inrichting van het landelijk gebied. De optimalisering van de waterhuishouding voor landbouw en natuur speelt in zulke plannen meestal een cruciale rol. De vraag is echter of daarbij voldoende rekening wordt gehouden met de mogelijke gevolgen van de veranderingen in het klimaat. Deze worden vooral onderzocht door wetenschappers op universiteiten en kennisinstituten, die zich doorgaans weinig bekommeren om gebiedsprocessen. In de provincie Gelderland zijn wetenschappers en mensen uit het veld onlangs samengekomen om de gevolgen van het warmer en grilliger wordende klimaat in kaart te brengen en na te denken over adaptieve maatregelen voor twee gebieden: Blauwe Bron en Baakse Beek
Search for single top quarks in the tau+jets channel using 4.8 fb of collision data
We present the first direct search for single top quark production using tau
leptons. The search is based on 4.8 fb of integrated luminosity
collected in collisions at =1.96 TeV with the D0 detector
at the Fermilab Tevatron Collider. We select events with a final state
including an isolated tau lepton, missing transverse energy, two or three jets,
one or two of them tagged. We use a multivariate technique to discriminate
signal from background. The number of events observed in data in this final
state is consistent with the signal plus background expectation. We set in the
tau+jets channel an upper limit on the single top quark cross section of
\TauLimObs pb at the 95% C.L. This measurement allows a gain of 4% in expected
sensitivity for the observation of single top production when combining it with
electron+jets and muon+jets channels already published by the D0 collaboration
with 2.3 fb of data. We measure a combined cross section of
\SuperCombineXSall pb, which is the most precise measurement to date.Comment: 12 pages, 5 figure
Measurement of Z/gamma*+jet+X angular distributions in ppbar collisions at sqrt{s}=1.96 TeV
We present the first measurements at a hadron collider of differential cross
sections for Z+jet+X production in delta phi(Z, jet), |delta y(Z, jet)| and
|y_boost(Z, jet)|. Vector boson production in association with jets is an
excellent probe of QCD and constitutes the main background to many small cross
section processes, such as associated Higgs production. These measurements are
crucial tests of the predictions of perturbative QCD and current event
generators, which have varied success in describing the data. Using these
measurements as inputs in tuning event generators will increase the
experimental sensitivity to rare signals.Comment: Published in Physics Letters B 682 (2010), pp. 370-380. 15 pages, 6
figure
Search for the standard model Higgs boson in tau final states
We present a search for the standard model Higgs boson using hadronically
decaying tau leptons, in 1 inverse femtobarn of data collected with the D0
detector at the Fermilab Tevatron ppbar collider. We select two final states:
tau plus missing transverse energy and b jets, and tau+ tau- plus jets. These
final states are sensitive to a combination of associated W/Z boson plus Higgs
boson, vector boson fusion and gluon-gluon fusion production processes. The
observed ratio of the combined limit on the Higgs production cross section at
the 95% C.L. to the standard model expectation is 29 for a Higgs boson mass of
115 GeV.Comment: publication versio
Search for charged Higgs bosons in top quark decays
We present a search for charged Higgs bosons in top quark decays. We analyze
the \eplus, \muplus, , , , \etau and \mutau final states from
top quark pair production events, using data from about 1 of
integrated luminosity recorded by the \dzero experiment at the Fermilab
Tevatron Collider. We consider different scenarios of possible charged Higgs
boson decays, one where the charged Higgs boson decays purely hadronically into
a charm and a strange quark, another where it decays into a lepton and a
neutrino and a third one where both decays appear. We extract limits on
the branching ratio for all these models. We use two methods,
one where the production cross section is fixed, and one where the
cross section is fitted simultaneously with . Based on the
extracted limits, we exclude regions in the charged Higgs boson mass and parameter space for different scenarios of the minimal supersymmetric
standard model.Comment: 10 pages, 8 figures, submitted to PL
Resposta in vitro e suscetibilidade ao Agrobacterium de duas cultivares de Stylosanthes guianensis
Age at first birth in women is genetically associated with increased risk of schizophrenia
Prof. Paunio on PGC:n jäsenPrevious studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a latent mechanism of genetic association between schizophrenia and age at first birth in women (AFB). Here, we use independent data from the UK Biobank (N = 38,892) to replicate the finding of an association between predicted genetic risk of schizophrenia and AFB in women, and to estimate the genetic correlation between schizophrenia and AFB in women stratified into younger and older groups. We find evidence for an association between predicted genetic risk of schizophrenia and AFB in women (P-value = 1.12E-05), and we show genetic heterogeneity between younger and older AFB groups (P-value = 3.45E-03). The genetic correlation between schizophrenia and AFB in the younger AFB group is -0.16 (SE = 0.04) while that between schizophrenia and AFB in the older AFB group is 0.14 (SE = 0.08). Our results suggest that early, and perhaps also late, age at first birth in women is associated with increased genetic risk for schizophrenia in the UK Biobank sample. These findings contribute new insights into factors contributing to the complex bio-social risk architecture underpinning the association between parental age and offspring mental health.Peer reviewe
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