Threading Memory: Performing Animacy in Text, Memorial, and Travel

This dissertation explores the process of creating and touring a community-sourced memorial quilt for the anti-mountaintop removal activist Julia “Judy” Bonds, who died in 2011. As a practice, the project positions memorialization as a possible framework for social movements to utilize when faced with loss that allows for actions that honor members of the movement while still engaging in consciousness raising and organizing efforts. From a theoretical standpoint, the practice of memorialization—especially when it is intentionally designed to align with the practices/legacy of the person(s) being remembered—is also considered through an object oriented ontology perspective, providing insight into the affective ways that a more personal/community base memorial can be considered as both a symbolic and real material representation of a person who has died.As a practice, the dissertation brings together work on object oriented ontology and travel as a way to highlight travel as a mobile object and performative practice, not just as a practice that allows for research to be presented, which can serve as a valuable site of knowledge generation and creation.Finally, this document is concerned with the materiality of textual representation, offering a series of experiments in performative writing to align with the larger goals of community organizing and environmental action, insisting that the documentation of our actions as well as the actions themselves can help to imagine new ways of being and knowing

The First Post-Kepler Brightness Dips of KIC 8462852

We present a photometric detection of the first brightness dips of the unique variable star KIC 8462852 since the end of the Kepler space mission in 2013 May. Our regular photometric surveillance started in October 2015, and a sequence of dipping began in 2017 May continuing on through the end of 2017, when the star was no longer visible from Earth. We distinguish four main 1-2.5% dips, named "Elsie," "Celeste," "Skara Brae," and "Angkor", which persist on timescales from several days to weeks. Our main results so far are: (i) there are no apparent changes of the stellar spectrum or polarization during the dips; (ii) the multiband photometry of the dips shows differential reddening favoring non-grey extinction. Therefore, our data are inconsistent with dip models that invoke optically thick material, but rather they are in-line with predictions for an occulter consisting primarily of ordinary dust, where much of the material must be optically thin with a size scale <<1um, and may also be consistent with models invoking variations intrinsic to the stellar photosphere. Notably, our data do not place constraints on the color of the longer-term "secular" dimming, which may be caused by independent processes, or probe different regimes of a single process

An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression

Dysregulated host responses to infection can lead to organ dysfunction and sepsis, causing millions of global deaths each year. To alleviate this burden, improved prognostication and biomarkers of response are urgently needed. We investigated the use of whole-blood transcriptomics for stratification of patients with severe infection by integrating data from 3149 samples from patients with sepsis due to community-acquired pneumonia or fecal peritonitis admitted to intensive care and healthy individuals into a gene expression reference map. We used this map to derive a quantitative sepsis response signature (SRSq) score reflective of immune dysfunction and predictive of clinical outcomes, which can be estimated using a 7- or 12-gene signature. Last, we built a machine learning framework, SepstratifieR, to deploy SRSq in adult and pediatric bacterial and viral sepsis, H1N1 influenza, and COVID-19, demonstrating clinically relevant stratification across diseases and revealing some of the physiological alterations linking immune dysregulation to mortality. Our method enables early identification of individuals with dysfunctional immune profiles, bringing us closer to precision medicine in infection.peer-reviewe

Ultralight vector dark matter search using data from the KAGRA O3GK run

Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM

Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M&gt;70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0&lt;e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

Transition towards a new global change science: Requirements for methodologies, methods, data and knowledge

Dealing with the challenges of global change requires a transition not only in society but also in the scientific community. Despite continued claims for more inter-disciplinary approaches, progress to date has been slow. This paper elaborates on the need for innova- tion in methodologies and knowledge, on the one hand, and methods and data, on the other, to build the foundations for dealing with the challenges from global change. Three questions related to the nature of global change, the dynamics of sustainability transitions and the role of human agency guide analyses on the state of the art, barriers for innovation and need for action. The analyses build on literature reviews, expert workshops and surveys which were conducted under the umbrella of RESCUE, a foresight activity funded by the European Science Foundation. The major recommendations focus on integrating environmental and human dimensions, bridging scales, data and knowledge for global change research and overcoming structural constraints to make global change research more policy relevant