Radio Follow-Up of Gravitational-Wave Triggers During Advanced Ligo O1

The American Astronomical Society. All rights reserved.We present radio follow-up observations carried out with the Karl G. Jansky Very Large Array during the first observing run (O1) of the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO). A total of three gravitational-wave triggers were followed-up during the 4 months of O1, from 2015 September to 2016 January. Two of these triggers, GW150914 and GW151226, are binary black hole (BH) merger events of high significance. A third trigger, G194575, was subsequently declared as an event of no interest (i.e., a false alarm). Our observations targeted selected optical transients identified by the intermediate Palomar Transient Factory in the Advanced LIGO error regions of the three triggers, and a limited region of the gravitational-wave localization area of G194575 not accessible to optical telescopes due to Sun constraints, where a possible high-energy transient was identified. No plausible radio counterparts to GW150914 and GW151226 were found, in agreement with expectations for binary BH mergers. We show that combining optical and radio observations is key to identifying contaminating radio sources that may be found in the follow-up of gravitational-wave triggers, such as emission associated with star formation and active galactic nuclei. We discuss our results in the context of the theoretical predictions for radio counterparts to gravitational-wave transients, and describe our future plans for the radio follow-up of Advanced LIGO (and Virgo) triggers. © 2016

Evolution of floral symmetry

Flowers can be classified into two basic types according to their symmetry: regular flowers have more than one plane of symmetry and irregular flowers have only a single plane of symmetry. The irregular condition is thought to have evolved many times independently from the regular one: most commonly through the appearance of asymmetry along the dorso-ventral axis of the flower. In most cases, the irregular condition is associated with a particular type of inflorescence architecture. To understand the molecular mechanism and evolutionary origin of irregular flowers, we have been investigating genes controlling asymmetry in Antirrhinum. Several mutations have been described in Antirrhinum, a species with irregular flowers, that reduce or eliminate asymmetry along the dorso-ventral axis. We describe the nature of these mutations and how they may be used to analyse the molecular mechanisms underlying floral evolution

Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression.

Anhedonia--which is defined as diminished pleasure from, or interest in, previously rewarding activities-is one of two cardinal symptoms of a major depressive episode. However, evidence suggests that standard treatments for depression do little to alleviate the symptoms of anhedonia and may cause reward blunting. Indeed, no therapeutics are currently approved for the treatment of anhedonia. Notably, over half of patients diagnosed with bipolar disorder experience significant levels of anhedonia during a depressive episode. Recent research into novel and rapid-acting therapeutics for depression, particularly the noncompetitive N-Methyl-D-aspartate receptor antagonist ketamine, has highlighted the role of the glutamatergic system in the treatment of depression; however, it is unknown whether ketamine specifically improves anhedonic symptoms. The present study used a randomized, placebo-controlled, double-blind crossover design to examine whether a single ketamine infusion could reduce anhedonia levels in 36 patients with treatment-resistant bipolar depression. The study also used positron emission tomography imaging in a subset of patients to explore the neurobiological mechanisms underpinning ketamine's anti-anhedonic effects. We found that ketamine rapidly reduced the levels of anhedonia. Furthermore, this reduction occurred independently from reductions in general depressive symptoms. Anti-anhedonic effects were specifically related to increased glucose metabolism in the dorsal anterior cingulate cortex and putamen. Our study emphasizes the importance of the glutamatergic system in treatment-refractory bipolar depression, particularly in the treatment of symptoms such as anhedonia

Early Ultraviolet Observations of Type IIn Supernovae Constrain the Asphericity of Their Circumstellar Material

© 2020. The American Astronomical Society. All rights reserved.. We present a survey of the early evolution of 12 Type IIn supernovae (SNe IIn) at ultraviolet and visible light wavelengths. We use this survey to constrain the geometry of the circumstellar material (CSM) surrounding SN IIn explosions, which may shed light on their progenitor diversity. In order to distinguish between aspherical and spherical CSM, we estimate the blackbody radius temporal evolution of the SNe IIn of our sample, following the method introduced by Soumagnac et al. We find that higher-luminosity objects tend to show evidence for aspherical CSM. Depending on whether this correlation is due to physical reasons or to some selection bias, we derive a lower limit between 35% and 66% for the fraction of SNe IIn showing evidence for aspherical CSM. This result suggests that asphericity of the CSM surrounding SNe IIn is common - consistent with data from resolved images of stars undergoing considerable mass loss. It should be taken into account for more realistic modeling of these events

The luminosity of supernovae of type Ia from TRGB distances and the value of H_0

Distances from the tip of the red-giant branch (TRGB) in the halo Population of galaxies - calibrated through RR Lyr stars as well as tied to Hipparcos parallaxes and further supported by stellar models - are used to determine the luminosity of six nearby type Ia supernovae (SN 2011fe, 2007sr, 1998bu, 1989B, 1972E, and 1937C). The result is M_V^corr = -19.41 +/- 0.05. If this value is applied to 62 SNe Ia with 3000< v < 20,000 km/s a large-scale value of the Hubble constant follows of H_0 = 64.0 +/- 1.6 +/- 2.0. The SN HST Project gave H_0 = 62.3 +/- 1.3 +/- 5.0 from ten Cepheid-calibrated SNe Ia (Sandage et al. 2006). The agreement of young Population I (Cepheids) and old, metal-poor Population II (TRGB) distance indicators is satisfactory. The combined weighted result is H_0 = 63.7 +/- 2.3 (i.e. +/-3.6%). The result can also be reconciled with WMAP5 data (Reid et al. 2010).Comment: 9 pages, 3 figures, 3 tables, accepted for publication in Astronomy and Astrophysic

Diversity of supernovae Ia determined using equivalent widths of Si II 4000

Spectroscopic and photometric properties of low and high-z supernovae Ia (SNe Ia) have been analyzed in order to achieve a better understanding of their diversity and to identify possible SN Ia sub-types. We use wavelet transformed spectra in which one can easily measure spectral features. We investigate the \ion{Si}{II} 4000 equivalent width (EW_w\lbrace\ion{Si}{II}\rbrace). The ability and, especially, the ease in extending the method to SNe at high-$z$ is demonstrated. We applied the method to 110 SNe Ia and found correlations between EW_w\lbrace\ion{Si}{II}\rbrace and parameters related to the light-curve shape for 88 supernovae with available photometry. No evidence for evolution of EW_w\lbrace\ion{Si}{II}\rbrace with redshift is seen. Three sub-classes of SNe Ia were confirmed using an independent cluster analysis with only light-curve shape, colour, and EW_w\lbrace\ion{Si}{II}\rbrace. SNe from high-$z$ samples seem to follow a similar grouping to nearby objects. The EW_w\lbrace\ion{Si}{II}\rbrace value measured on a single spectrum may point towards SN Ia sub-classification, avoiding the need for expansion velocity gradient calculations.Comment: 12 pages, 5 figure

The type Ia supernova SNLS-03D3bb from a super-Chandrasekhar-mass white dwarf star

The acceleration of the expansion of the universe, and the need for Dark Energy, were inferred from the observations of Type Ia supernovae (SNe Ia). There is consensus that SNe Ia are thermonuclear explosions that destroy carbon-oxygen white dwarf stars that accrete matter from a companion star, although the nature of this companion remains uncertain. SNe Ia are thought to be reliable distance indicators because they have a standard amount of fuel and a uniform trigger -- they are predicted to explode when the mass of the white dwarf nears the Chandrasekhar mass -- 1.4 solar masses. Here we show that the high redshift supernova SNLS-03D3bb has an exceptionally high luminosity and low kinetic energy that both imply a super-Chandrasekhar mass progenitor. Super-Chandrasekhar mass SNe Ia should preferentially occur in a young stellar population, so this may provide an explanation for the observed trend that overluminous SNe Ia only occur in young environments. Since this supernova does not obey the relations that allow them to be calibrated as standard candles, and since no counterparts have been found at low redshift, future cosmology studies will have to consider contamination from such events.Comment: 9 pages, 4 figures. To appear in Nature Sept. 21. Accompanying News & Views in same issue. Supplementary information available at www.nature.com/natur

Type Ia Supernovae as Stellar Endpoints and Cosmological Tools

Empirically, Type Ia supernovae are the most useful, precise, and mature tools for determining astronomical distances. Acting as calibrated candles they revealed the presence of dark energy and are being used to measure its properties. However, the nature of the SN Ia explosion, and the progenitors involved, have remained elusive, even after seven decades of research. But now new large surveys are bringing about a paradigm shift --- we can finally compare samples of hundreds of supernovae to isolate critical variables. As a result of this, and advances in modeling, breakthroughs in understanding all aspects of SNe Ia are finally starting to happen.Comment: Invited review for Nature Communications. Final published version. Shortened, update

Luminally expressed gastrointestinal biomarkers

Introduction: A biomarker is a measurable indicator of normal biologic processes, pathogenic processes or pharmacological responses. The identification of a useful biomarker is challenging, with several hurdles to overcome before clinical adoption. This review gives a general overview of a range of biomarkers associated with inflammatory bowel disease or colorectal cancer along the gastrointestinal tract. Areas covered: These markers include those that are already clinically accepted, such as inflammatory markers such as faecal calprotectin, S100A12 (Calgranulin C), Fatty Acid Binding Proteins (FABP), malignancy markers such as Faecal Occult Blood, Mucins, Stool DNA, Faecal microRNA (miRNA), other markers such as Faecal Elastase, Faecal alpha-1-antitrypsin, Alpha2-macroglobulin and possible future markers such as microbiota, volatile organic compounds and pH. Expert commentary: There are currently a few biomarkers that have been sufficiently validated for routine clinical use at present such as FC. However, many of these biomarkers continue to be limited in sensitivity and specificity for various GI diseases. Emerging biomarkers have the potential to improve diagnosis and monitoring but further study is required to determine efficacy and validate clinical utility