Slavery in the Bengal Presidency Under East India Company Rule, 1772-1843.

The thesis is an attempt to trace the history of slavery and its abolition in the Bengal Presidency under the East India Company's rule from 1772 to 1843. The first Chapter defines slavery and traces its history in the early and medieval periods of Indian history before the advent of the British power. It explains the reasons for its sanction as a punishment for the armed dacoits in 1772, and the various sources of slavery and the ways the slaves were procured during the Company's rule. The second chapter deals with domestic slavery in the Bengal Presidency in Hindu, Muslim and European families in the late eighteenth and the first half of the 19th century. The third Chapter is a detailed study of agrestic slavery in the Bengal Presidency and its importance as a social and economic institution in the Country. The fourth Chapter surveys the history of the seaborne slave-trade and deals with the measures taken by the Company's Government and the British Parliament to secure its gradual abolition. The fifth and sixth Chapters are devoted to two areas, Assam and Arakan, which stand rather apart, in the social and political structure from the rest of the Bengal Presidency. The seventh Chapter seeks to examine the British attitude towards slavery and the slave trade in India and gives an account of the ameliorative measures taken by the Company's Government and the British Parliament to suppress slavery and slave-trade. The roles played by the utilitarians and by such Company officials as Richardson, Metcalfe, Leycester, Harrington and Neufville to abolish slavery from India are considered and the reason for their failure. The eighth Chapter discusses the economic and social changes in Britain which led to the emergence of an anti-slavery movement strong enough to secure the institution of the Law Commission. It concludes with a study of the Law Commission's work and the abolition of slavery in 1843

Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe

Chapter 12 - Antibiotics in the management of tuberculosis and cancer

Drugs that were formerly thought to be life-saving miracles are now rendered useless due to pathogen's defense mechanisms. It is more difficult to fight or cure the infectious disease and to develop new antibiotics due to increase in antibiotic resistance. Mycobacterium tuberculosis is one of the world's most deadly infections and causes of mortality. Recent advances in gene therapy, genetic engineering, and last but not least, immunobiology, establish a reasonable foundation for the research and development of more effective tuberculosis vaccines. Cancer is the uncontrolled proliferation of cells in our bodies that might result in death. Normal cells are typically invaded and destroyed by cancer cells. Due to the complicated nature of cancer, it is necessary to analyze at molecular level, and we hope biotechnologists will develop fast and promising way of more techniques and discovery items in order to decrease the cause of death and to limit suffering percentage of cancerous patients, increasing the drug efficacy, selectivity, and mode of action. Because of advancements in screening, targeted and immunological therapy, big data, computational techniques, and major new knowledge of cancer biology, many diseases could be prevented, detected, diagnosed, and treated. In order to combat the global problem of antibiotic resistance, fundamental research and biotechnology are critical. The widespread adoption of these strategies will be critical in the creation of novel antibiotics for the treatment and prevention of tuberculosis and cancer

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Multiplicity dependence of light (anti-)nuclei production in p–Pb collisions at sNN=5.02 TeV

The measurement of the deuteron and anti-deuteron production in the rapidity range −1 < y < 0 as a function of transverse momentum and event multiplicity in p–Pb collisions at √sNN = 5.02 TeV is presented. (Anti-)deuterons are identified via their specific energy loss dE/dx and via their time-of- flight. Their production in p–Pb collisions is compared to pp and Pb–Pb collisions and is discussed within the context of thermal and coalescence models. The ratio of integrated yields of deuterons to protons (d/p) shows a significant increase as a function of the charged-particle multiplicity of the event starting from values similar to those observed in pp collisions at low multiplicities and approaching those observed in Pb–Pb collisions at high multiplicities. The mean transverse particle momenta are extracted from the deuteron spectra and the values are similar to those obtained for p and particles. Thus, deuteron spectra do not follow mass ordering. This behaviour is in contrast to the trend observed for non-composite particles in p–Pb collisions. In addition, the production of the rare 3He and 3He nuclei has been studied. The spectrum corresponding to all non-single diffractive p-Pb collisions is obtained in the rapidity window −1 < y < 0 and the pT-integrated yield dN/dy is extracted. It is found that the yields of protons, deuterons, and 3He, normalised by the spin degeneracy factor, follow an exponential decrease with mass number

Relative particle yield fluctuations in Pb-Pb \text{ Pb-Pb } collisions at sNN=2.76 TeV\sqrt{s_\mathrm{{NN}}} =2.76\hbox { TeV}

First results on $\hbox {K}/\pi$ , $\hbox {p}/\pi$ and K/p fluctuations are obtained with the ALICE detector at the CERN LHC as a function of centrality in $\text{ Pb-Pb }$ collisions at $\sqrt{s_\mathrm{{NN}}} =2.76\hbox { TeV}$ . The observable $\nu _{\mathrm{dyn}}$ , which is defined in terms of the moments of particle multiplicity distributions, is used to quantify the magnitude of dynamical fluctuations of relative particle yields and also provides insight into the correlation between particle pairs. This study is based on a novel experimental technique, called the Identity Method, which allows one to measure the moments of multiplicity distributions in case of incomplete particle identification. The results for $\hbox {p}/\pi$ show a change of sign in $\nu _{\mathrm{dyn}}$ from positive to negative towards more peripheral collisions. For central collisions, the results follow the smooth trend of the data at lower energies and $\nu _{\mathrm{dyn}}$ exhibits a change in sign for $\hbox {p}/\pi$ and K/p

Relative particle yield fluctuations in Pb-Pb collisions at sNN=2.76\sqrt{s_{\rm NN}} = 2.76 TeV

First results on K/$\pi$, p/$\pi$ and K/p fluctuations are obtained with the ALICE detector at the CERN LHC as a function of centrality in Pb-Pb collisions at $\sqrt{s_{\rm NN}}=2.76$ TeV. The observable $\nu_{\rm dyn}$, which is defined in terms of the moments of particle multiplicity distributions, is used to quantify the magnitude of dynamical fluctuations of relative particle yields and also provides insight into the correlation between particle pairs. This study is based on a novel experimental technique, called the Identity Method, which allows one to measure the moments of multiplicity distributions in case of incomplete particle identification. The results for p/$\pi$ show a change of sign in $\nu_{\rm dyn}$ from positive to negative towards more peripheral collisions. For central collisions, the results follow the smooth trend of the data at lower energies and $\nu_{\rm dyn}$ exhibits a change in sign for p/$\pi$ and K/p.First results on $\hbox {K}/\pi$ , $\hbox {p}/\pi$ and K/p fluctuations are obtained with the ALICE detector at the CERN LHC as a function of centrality in $\text{ Pb--Pb }$ collisions at $\sqrt{s_\mathrm{{NN}}} =2.76\hbox { TeV}$ . The observable $\nu _{\mathrm{dyn}}$ , which is defined in terms of the moments of particle multiplicity distributions, is used to quantify the magnitude of dynamical fluctuations of relative particle yields and also provides insight into the correlation between particle pairs. This study is based on a novel experimental technique, called the Identity Method, which allows one to measure the moments of multiplicity distributions in case of incomplete particle identification. The results for $\hbox {p}/\pi$ show a change of sign in $\nu _{\mathrm{dyn}}$ from positive to negative towards more peripheral collisions. For central collisions, the results follow the smooth trend of the data at lower energies and $\nu _{\mathrm{dyn}}$ exhibits a change in sign for $\hbox {p}/\pi$ and K/p

Constraints on jet quenching in p-Pb collisions at sNN\mathbf{\sqrt{s_{NN}}} = 5.02 TeV measured by the event-activity dependence of semi-inclusive hadron-jet distributions

The ALICE Collaboration reports the measurement of semi-inclusive distributions of charged-particle jets recoiling from a high-transverse momentum trigger hadron in p–Pb collisions at sNN=5.02 TeV. Jets are reconstructed from charged-particle tracks using the anti- kT algorithm with resolution parameter R=0.2 and 0.4. A data-driven statistical approach is used to correct the uncorrelated background jet yield. Recoil jet distributions are reported for jet transverse momentum 15<pT,jetch<50GeV/c and are compared in various intervals of p–Pb event activity, based on charged-particle multiplicity and zero-degree neutral energy in the forward (Pb-going) direction. The semi-inclusive observable is self-normalized and such comparisons do not require the interpretation of p–Pb event activity in terms of collision geometry, in contrast to inclusive jet observables. These measurements provide new constraints on the magnitude of jet quenching in small systems at the LHC. In p–Pb collisions with high event activity, the average medium-induced out-of-cone energy transport for jets with R=0.4 and 15<pT,jetch<50GeV/c is measured to be less than 0.4 GeV/c at 90% confidence, which is over an order of magnitude smaller than a similar measurement for central Pb–Pb collisions at sNN=2.76TeV . Comparison is made to theoretical calculations of jet quenching in small systems, and to inclusive jet measurements in p–Pb collisions selected by event activity at the LHC and in d–Au collisions at RHIC

First measurement of Ξc0\Xi_{\rm c}^0 production in pp collisions at s\mathbf{\sqrt{s}} = 7 TeV

The production of the charm-strange baryon Ξc0 is measured for the first time at the LHC via its semileptonic decay into e Ξ−+νe in pp collisions at s=7 TeV with the ALICE detector. The transverse momentum ( pT ) differential cross section multiplied by the branching ratio is presented in the interval 1<pT<8 GeV/c at mid-rapidity, |y|<0.5 . The transverse momentum dependence of the Ξc0 baryon production relative to the D0 meson production is compared to predictions of event generators with various tunes of the hadronisation mechanism, which are found to underestimate the measured cross-section ratio