Zihin Yetersizliği Olan Ortaokul Öğrencilerinin Bulunduğu Bir Sınıfta Öğretim Etkinliklerinin Teknoloji Desteği ile Geliştirilmesi

The purpose of this study is to create a class supported by advanced technological tools (e.g. tablet computer, interactive boards) in a special education middle school for students with intellectual disability; conduct technology-based instructional activities; determine the problems likely to emerge in this process and solve these problems; and improve students’ competencies in the Science and Technology course. This study, which is an action research, was conducted in three stages: “Determining the Situation”, “Implementation”; and “Monitoring”. This paper presents the implementation and monitoring stages of the study. The research participants are 11 sixth grade students with mild intellectual disability receiving education at an official special education middle school, their parents, two classroom teachers of the intellectually-disabled, validity committee members, dissertation supervision committee members, and the researcher. The research data were obtained from video-recordings, field notes, the researcher’s diary, daily lesson plans, validity committee meeting decisions, decisions taken in the reflection and planning meetings with the teachers, semi-structured interviews, artifacts, criterion-referenced test, check-lists, and official documents. The data obtained during and at the end of the research process were subjected to content analysis via Nvivo 10.The findings indicated that identifying student needs in the integration process, providing and developing electronic contents according to these needs, and planning instruction activities by taking these needs into consideration are important. In addition, the research provided very detailed data concerning the problems likely to be encountered in the integration of technology into a natural teaching environment. It was stressed that the problems encountered during the use of technology in instruction activities may lead to new behavioral problems, and teachers have to take measures against these situations. The integration of technology into the Science and Technology course curriculum improved the students’ academic performance. It also contributed to the teachers. The findings were discussed in the light of other studies in the literature, and recommendations were put forward for practice and further studies.Bu araştırmanın amacı; zihin yetersizliği olan öğrencilerin eğitim gördüğü bir özel eğitim ortaokulunda ileri düzey teknolojik araçlar (tablet bilgisayar, etkileşimli tahta) ile desteklenen bir sınıfın oluşturularak teknoloji destekli öğretim etkinliklerinin uygulanması ve bu süreçte ortaya çıkabilecek sorunların belirlenerek çözümlenmesi ve öğrencilerin Fen ve Teknoloji dersindeki öğrenme yeterliklerinin artırılmasıdır. Eylem araştırması olarak desenlenen araştırma, “Durum Saptama”, “Uygulama” ve “İzleme” olmak üzere üç aşamada gerçekleştirilmiştir. Bu çalışmada araştırmanın uygulama ve izleme aşamasına yer verilmiştir. Araştırmanın katılımcıları, resmi bir özel eğitim ortaokulunda eğitim alan altıncı sınıf, hafif düzeyde zihin yetersizliği olan 11 öğrenci, öğrencilerin aileleri, iki zihin engelliler sınıf öğretmeni, geçerlik komitesi ve tez izleme komitesi üyeleri ve araştırmacıdır. Araştırma verileri, görüntü kayıtları, saha notları, araştırmacı günlüğü, günlük ders planları, geçerlik komitesi toplantı kararları, öğretmenler ile yapılan yansıtma ve birlikte planlama toplantısı kararları, yarı yapılandırılmış görüşmeler, süreç ürünleri, ölçüt bağımlı test, kontrol listeleri ve resmi belgelerden elde edilmiştir. Araştırma sürecinde ve sonunda elde edilen veriler içerik analizi tekniği ile Nvivo 10 programında analiz edilmiştir.Bulgular, entegrasyon sürecinde öğrenci gereksinimlerinin belirlenmesinin, öğrenci gereksinimlerine göre elektronik içeriklerin temin edilmesi ve geliştirilmesinin, öğretim etkinliklerinin planlanmasının önemli aşamalar olduğunu göstermiştir. Bunun yanında araştırma, doğal bir öğretim ortamında teknoloji entegrasyonunda karşılaşılabilecek sorunlara ilişkin çok detaylı veriler sunmuştur. Teknolojinin öğretim etkinliklerinde kullanımı sırasında karşılaşılan sorunların yeni davranış probemlerine yol açabileceği, öğretmenlerin bu durumlara ilişkin önlemler almaları gerektiği vurgulanmıştır. Teknolojinin Fen ve Teknoloji dersi programına entegrasyonu ile öğrencilerin akademik performanslarında gelişmeler kaydedilmiştir. Ayrıca, uygulamanın öğretmenlere de olumlu katkılar sağladığı belirlenmiştir. Alan yazındaki diğer çalışmalar ışığında bulgular tartışılarak uygulamaya ve ileri araştırmalara yönelik öneriler sunulmuştur

Antisosyal Davranışları Önlemeye Yönelik “Başarıya İlk Adım Programı” Türkçe Versiyonu’nun Etkililiği

The purpose of this study was to examine the effectiveness of the Turkish version of the First Step to Success (TFSS) early intervention program on problem behaviors, social skills, and academic competence of at-risk students for antisocial behaviors in Turkey. Participants consisted of a total number of 102 students (53 students in experimental and 49 students in control group) and experimental group students’ teachers and mothers. Experimental group students were subjected to implementation of TFSS while control group students were not. Results revealed significant differences between the scores of two groups on problem behaviors and social skills. Moreover, significant decreases in experimental group students’ problem behavior scores and significant increases in their social skills and academic competence scores were observed. High levels of satisfaction were reported by experimental group students’ teachers and mothers. Results are being discussed.Bu çalışmanın amacı, Başarıya İlk Adım Programı Türkçe Versiyonu’nun (BİA-TV) antisosyal davranışlar açısından riskli olan öğrencilerin problem davranışları, sosyal becerileri ve akademik yeterlilikleri üzerindeki etkililiğini incelemektir. Çalışma 53’ü deney ve 49’u kontrol grubunda olmak üzere 31’i anasınıfından 37 birinci sınıf ve 34’ü ikinci sınıftan 102 öğrenciyle gerçekleştirilmiştir. Deney grubu öğrencileri ile BİA-AV programı uygulanırken, kontrol grubu ile herhangi bir uygulama gerçekleştirilmemiştir. Bulgular iki grubun problem davranışları ve sosyal beceri puanları arasında anlamlı farklılıklar olduğunu göstermiştir. Programın deney grubu öğrencilerinin problem davranışlarında anlamlı düşüşe, sosyal beceri ve akademik yeterlilik puanlarında anlamlı artışa yol açtığı gözlenmiştir. Katılımcıların öğretmenleri ve annelerinin memnuniyet düzeyleri yüksek bulunmuştur. Bulgular tartışılmıştır

Beach Center Aile Yaşam Kalitesi Ölçeği’nin Türkçe Uyarlama,Geçerlik ve Güvenirlik Çalışması

The aim of this study is to adapt the Beach Center Family Quality of Life Scale to Turkish by examining its psychometric properties. Participants were 368 mothers of children with disabilities from 7 cities of Turkey. In this study firstly, the language equivalency between English and Turkish forms were tested. After that confirmatory factor analysis, criterion validity, the Cronbach’s alpha correlation coefficients, and split-half reliabilities, corrected item-total correlations and t-tests between items’ means of upper 27%-lover 27% points of the Turkish form were examined. Results showed that the scale called Beach Center Family Quality of Life Scale as a valid and reliable instrument can be used in the fields of intellectual and developmental disabilities and special education.Bu araştırmanın amacı, Beach Center Aile Yaşam Kalitesi Ölçeği’nin Türkçeye uyarlanması ve ülkemizdeki örneklem üzerinden psikometrik özelliklerinin belirlenmesidir. Araştırma Türkiye’de 7 farklı ilde gelişimsel yetersizliği olan çocuğa sahip 368 anne ile gerçekleştirilmiştir. Dilsel eşdeğerliğin yüksek düzeyde olduğu gözlenen ölçeğin, ön uygulama ve uzman görüşü sonrasında doğrulayıcı faktör analizi, ölçüt bağıntılı geçerlik, Cronbach Alfa iç tutarlık güvenirliği ve iki yarı güvenirliği, madde toplam korelasyonu ve t-testi kullanılarak üst % 27 ile alt % 27 grupların madde ortalamaları arasındaki farkların anlamlılığı incelenmiştir. Yapılan analiz bulguları, Beach Center Aile Yaşam Kalitesi Ölçeği Türkçe Formu’nun ülkemizde gelişimsel yetersizlik alanında aile yaşam kalitesinin ölçülmesinde geçerli ve güvenilir bir ölçme aracı olarak kullanılabileceğini ortaya koyar niteliktedir

Assessment of children presenting with rheumatic complaints to a tertiary center in Turkey: differences in an Eastern Mediterranean population

PubMe

The Role of Mobile Health Technologies in Allergy Care:an EAACI Position Paper

Mobile health (mHealth) uses mobile communication devices such as smartphones and tablet computers to support and improve health-related services, data and information flow, patient self-management, surveillance, and disease management from the moment of first diagnosis to an optimized treatment. The European Academy of Allergy and Clinical Immunology created a task force to assess the state of the art and future potential of mHealth in allergology. The task force endorsed the "Be He@lthy, Be Mobile" WHO initiative and debated the quality, usability, efficiency, advantages, limitations, and risks of mobile solutions for allergic diseases. The results are summarized in this position paper, analyzing also the regulatory background with regard to the "General Data Protection Regulation" and Medical Directives of the European Community. The task force assessed the design, user engagement, content, potential of inducing behavioral change, credibility/accountability, and privacy policies of mHealth products. The perspectives of healthcare professionals and allergic patients are discussed, underlining the need of thorough investigation for an effective design of mHealth technologies as auxiliary tools to improve quality of care. Within the context of precision medicine, these could facilitate the change in perspective from clinician- to patient-centered care. The current and future potential of mHealth is then examined for specific areas of allergology, including allergic rhinitis, aerobiology, allergen immunotherapy, asthma, dermatological diseases, food allergies, anaphylaxis, insect venom, and drug allergy. The impact of mobile technologies and associated big data sets are outlined. Facts and recommendations for future mHealth initiatives within EAACI are listed

Genetic landscape of a large cohort of Primary Ovarian Insufficiency : New genes and pathways and implications for personalized medicine

Background Primary Ovarian Insufficiency (POI), a public health problem, affects 1-3.7% of women under 40 yield-ing infertility and a shorter lifespan. Most causes are unknown. Recently, genetic causes were identified, mostly in single families. We studied an unprecedented large cohort of POI to unravel its molecular pathophysiology.Methods 375 patients with 70 families were studied using targeted (88 genes) or whole exome sequencing with pathogenic/likely-pathogenic variant selection. Mitomycin-induced chromosome breakages were studied in patients' lymphocytes if necessary. Findings A high-yield of 29.3% supports a clinical genetic diagnosis of POI. In addition, we found strong evidence of pathogenicity for nine genes not previously related to a Mendelian phenotype or POI: ELAVL2, NLRP11, CENPE, SPATA33, CCDC150, CCDC185, including DNA repair genes: C17orf53(HROB), HELQ, SWI5 yielding high chromo-somal fragility. We confirmed the causal role of BRCA2, FANCM, BNC1, ERCC6, MSH4, BMPR1A, BMPR1B, BMPR2, ESR2, CAV1, SPIDR, RCBTB1 and ATG7 previously reported in isolated patients/families. In 8.5% of cases, POI is the only symptom of a multi-organ genetic disease. New pathways were identified: NF-kB, post-translational regulation, and mitophagy (mitochondrial autophagy), providing future therapeutic targets. Three new genes have been shown to affect the age of natural menopause supporting a genetic link.Interpretation We have developed high-performance genetic diagnostic of POI, dissecting the molecular pathogene-sis of POI and enabling personalized medicine to i) prevent/cure comorbidities for tumour/cancer susceptibility genes that could affect life-expectancy (37.4% of cases), or for genetically-revealed syndromic POI (8.5% of cases), ii) predict residual ovarian reserve (60.5% of cases). Genetic diagnosis could help to identify patients who may benefit from the promising in vitro activation-IVA technique in the near future, greatly improving its success in treating infertility.Funding Universite? Paris Saclay, Agence Nationale de Biome?decine.Copyright (c) 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)Peer reviewe

The HELLP syndrome: Clinical issues and management. A Review

<p>Abstract</p> <p>Background</p> <p>The HELLP syndrome is a serious complication in pregnancy characterized by haemolysis, elevated liver enzymes and low platelet count occurring in 0.5 to 0.9% of all pregnancies and in 10–20% of cases with severe preeclampsia. The present review highlights occurrence, diagnosis, complications, surveillance, corticosteroid treatment, mode of delivery and risk of recurrence.</p> <p>Methods</p> <p>Clinical reports and reviews published between 2000 and 2008 were screened using Pub Med and Cochrane databases.</p> <p>Results and conclusion</p> <p>About 70% of the cases develop before delivery, the majority between the 27th and 37th gestational weeks; the remainder within 48 hours after delivery. The HELLP syndrome may be complete or incomplete. In the Tennessee Classification System diagnostic criteria for HELLP are haemolysis with increased LDH (> 600 U/L), AST (≥ 70 U/L), and platelets < 100·10⁹/L. The Mississippi Triple-class HELLP System further classifies the disorder by the nadir platelet counts. The syndrome is a progressive condition and serious complications are frequent. Conservative treatment (≥ 48 hours) is controversial but may be considered in selected cases < 34 weeks' gestation. Delivery is indicated if the HELLP syndrome occurs after the 34th gestational week or the foetal and/or maternal conditions deteriorate. Vaginal delivery is preferable. If the cervix is unfavourable, it is reasonable to induce cervical ripening and then labour. In gestational ages between 24 and 34 weeks most authors prefer a single course of corticosteroid therapy for foetal lung maturation, either 2 doses of 12 mg betamethasone 24 hours apart or 6 mg or dexamethasone 12 hours apart before delivery. Standard corticosteroid treatment is, however, of uncertain clinical value in the maternal HELLP syndrome. High-dose treatment and repeated doses should be avoided for fear of long-term adverse effects on the foetal brain. Before 34 weeks' gestation, delivery should be performed if the maternal condition worsens or signs of intrauterine foetal distress occur. Blood pressure should be kept below 155/105 mmHg. Close surveillance of the mother should be continued for at least 48 hours after delivery.</p