173 research outputs found

    Vasi in pietre dure o marmi pregiati

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    Catalogo dei frammenti di vasi in pietre dure o marmi pregiati della collezione di Evan Gorga, con documentazione delle forme

    Chromogranin A fragments modulate cell adhesion. Identification and characterization of a pro-adhesive domain.

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    Although several functions have been suggested for chromogranin A, a glycoprotein secreted by many neuroendocrine cells, the physiological role of this protein and of its proteolytic fragments has not been established. We have found that mixtures of chromogranin A fragments can inhibit fibroblast adhesion. The anti-adhesive activity was converted into pro-adhesive activity by limited trypsin treatment. Pro-adhesive effects were observed also with recombinant N-terminal fragments corresponding to residues 1–78 and 1–115 and with a synthetic peptide encompassing the residues 7–57. These fragments induced adhesion and spreading of fibroblasts on plates coated with collagen I or IV, laminin, fetal calf serum (FCS) but not on bovine serum albumin. The long incubation time required for adhesion assays (4 h) and the FCS requirements for optimal adhesion suggest that the adhesive activity is likely indirect and requires other proteins present in the FCS or made by the cells. These findings suggest that chromogranin A and its fragments could play a role in the regulation of cell adhesion. Since chromogranin A is concentrated and stored within granules and rapidly released by neuroendocrine cells and neurons after an appropriate stimulus, this protein could be important for the local control of cell adhesion by stimulated cells

    Super-heavy fermion material as metallic refrigerant for adiabatic demagnetization cooling

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    Low-temperature refrigeration is of crucial importance in fundamental research of condensed matter physics, as the investigations of fascinating quantum phenomena, such as superconductivity, superfluidity and quantum criticality, often require refrigeration down to very low temperatures. Currently, cryogenic refrigerators with 3^3He gas are widely used for cooling below 1 Kelvin. However, usage of the gas is being increasingly difficult due to the current world-wide shortage. Therefore, it is important to consider alternative methods of refrigeration. Here, we show that a new type of refrigerant, super-heavy electron metal, YbCo2_2Zn20_{20}, can be used for adiabatic demagnetization refrigeration, which does not require 3He gas. A number of advantages includes much better metallic thermal conductivity compared to the conventional insulating refrigerants. We also demonstrate that the cooling performance is optimized in Yb1x_{1-x}Scx_xCo2_2Zn20_{20} by partial Sc substitution with xx\sim0.19. The substitution induces chemical pressure which drives the materials close to a zero-field quantum critical point. This leads to an additional enhancement of the magnetocaloric effect in low fields and low temperatures enabling final temperatures well below 100 mK. Such performance has up to now been restricted to insulators. Since nearly a century the same principle of using local magnetic moments has been applied for adiabatic demagnetization cooling. This study opens new possibilities of using itinerant magnetic moments for the cryogen-free refrigeration

    Erratum to nodal management and upstaging of disease. Initial results from the Italian VATS Lobectomy Registry

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    [This corrects the article DOI: 10.21037/jtd.2017.06.12.]

    Palazzo Massimo alle Terme. Le collezioni

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    Catalogo aggiornato delle collezioni di sculture in marmo e bronzo, delle pitture e dei mosaici del Museo Nazionale Romano collocati in Palazzo Massimo, Rom

    Le sculture Farnese. 1. Le sculture ideali, testi di C. Capaldi, S.Pafumi

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    Catalogo scientifico della serie delle sculture ideali della collezione Farnese, con ricostruzione delle vicende collezionistiche e antiquarie, nonché della fortuna di ciascun elemento

    A proposito di un recente studio sui vasi antichi in pietra dura.

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    Riesame di un corpus di recente edizione di vasi in pietra dura, con ampia rassegna di nuovo materiale e discussione dei problemi di datazione, officine, provenienze

    Il sarcofago con Nekyia di Villa Giulia restaurato. Ancora sull'inizio della produzione dei sarcofagi a Roma.

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    Partendo da una nuova presentazione del sarcofago con scene dell'Oltretomba del Museo di Villa Giulia, nel quale è stato reintegrato un ampio frammento della fronte recuperato nel Museo Nazionale Romano, viene ampliato il numero dei sarcofagi modanati databili in età augustea,con importanti considerazioni sul rituale funerario, comprendente l' uso della mummificazione

    Gemme antiche in età neoclassica: egmagmata, gazofilaci, dactyliothecae.

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    Ampio quadro sulla storia del collezionismo di calchi di gemme nel XVIII e XIX secolo, come strumento per la conoscenza della glittica antica e per la formazione del gusto neoclassico, con osservazioni sul funzionamento delle botteghe produttrici e edizione di documenti inediti
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