964 research outputs found
l-Leucine supplemented whey protein. Doseâresponse effect on heart mTOR activation of sedentary and trained rats
AbstractThe aim of the study was to investigate the effect of leucine supplementation combined with exercise and whey protein in cardiac mTOR anabolic pathway. Ninety-six weanling male Wistar rats were divided into eight groups and fed diets containing either casein or WP plus increasing levels (0, 3, 4.5 and 6% of diet) of l-leucine for 30days. A parallel set of eight groups was exercised for comparison. Serum aspartate amino transferase, alanine aminotransferase, creatine kinase, lactate dehydrogenase and branched chain amino acids were determined by standard methods, and mammalian target of rapamycin (mTOR) and p70S6K by the Western blot analysis. Chronic l-leucine supplementation was capable of increasing both mTOR and p70S6K phosphorylation in the heart in a dose-dependent fashion, independent of the type of dietary protein in both groups, sedentary and exercised, but the exercise potentialized the activation of the anabolic pathway. The content of protein in heart increase with l-leucine supplementation and the heart mass relativized by body mass did not change. In conclusion, the combination of l-leucine and milk proteins (casein or whey protein) has the potential to increase the mTOR pathway in the cardiac muscle without increasing the heart mass. The novelty of this study is to show the effectiveness of a blend of leucine and whey protein as a viable alternative to maximize the activation of the anabolic pathway of cardiac muscle and that the exercise can improve this process
The radial BAO scale and Cosmic Shear, a new observable for Inhomogeneous Cosmologies
As an alternative explanation of the dimming of distant supernovae it has
recently been advocated that we live in a special place in the Universe near
the centre of a large spherical void described by a Lemaitre-Tolman-Bondi (LTB)
metric. In this scenario, the Universe is no longer homogeneous and isotropic,
and the apparent late time acceleration is actually a consequence of spatial
gradients. We propose in this paper a new observable, the normalized cosmic
shear, written in terms of directly observable quantities, and calculable in
arbitrary inhomogeneous cosmologies. This will allow future surveys to
determine whether we live in a homogeneous universe or not. In this paper we
also update our previous observational constraints from geometrical measures of
the background cosmology. We include the Union Supernovae data set of 307 Type
Ia supernovae, the CMB acoustic scale and the first measurement of the radial
baryon acoustic oscillation scale. Even though the new data sets are
significantly more constraining, LTB models -- albeit with slightly larger
voids -- are still in excellent agreement with observations, at chi^2/d.o.f. =
307.7/(310-4)=1.005. Together with the paper we also publish the updated
easyLTB code used for calculating the models and for comparing them to the
observations.Comment: 18 pages, 8 figures, the code can be downloaded at
http://www.phys.au.dk/~haugboel/software.shtm
Two-dimensional quantum-corrected black hole in a finite size cavity
We consider the gravitation-dilaton theory (not necessarily exactly
solvable), whose potentials represent a generic linear combination of an
exponential and linear functions of the dilaton. A black hole, arising in such
theories, is supposed to be enclosed in a cavity, where it attains thermal
equilibrium, whereas outside the cavity the field is in the Boulware state. We
calculate quantum corrections to the Hawking temperature , with the
contribution from the boundary taken into account. Vacuum polarization outside
the shell tend to cool the system. We find that, for the shell to be in the
thermal equilibrium, it cannot be placed too close to the horizon. The quantum
corrections to the mass due to vacuum polarization vanish in spite of non-zero
quantum stresses. We discuss also the canonical boundary conditions and show
that accounting for the finiteness of the system plays a crucial role in some
theories (e.g., CGHS), where it enables to define the stable canonical
ensemble, whereas consideration in an infinite space would predict instability.Comment: 21 pages. In v.2 misprints corrected. To appear in Phys. Rev.
Quantum singularities in a model of f(R) Gravity
The formation of a naked singularity in a model of f(R) gravity having as
source a linear electromagnetic field is considered in view of quantum
mechanics. Quantum test fields obeying the Klein-Gordon, Dirac and Maxwell
equations are used to probe the classical timelike naked singularity developed
at r=0. We prove that the spatial derivative operator of the fields fails to be
essentially self-adjoint. As a result, the classical timelike naked singularity
remains quantum mechanically singular when it is probed with quantum fields
having different spin structures.Comment: 12 pages, final version. Accepted for publication in EPJ
Occupational stress in health professionals: a study with Portuguese Nurses
Este trabalho analisa o estresse ocupacional em 286 enfermeiros de hospitais e centros de saĂșde portugueses. Avaliaram-se as fontes de estresse, o burnout, os problemas de saĂșde fĂsica, a satisfação e a realização profissional. Os resultados apontaram 30% de enfermeiros com experiĂȘncias significativas de estresse e 15% com problemas de exaustĂŁo emocional. As anĂĄlises de regressĂŁo mĂșltipla apontaram maior capacidade preditiva das dimensĂ”es de estresse na exaustĂŁo emocional, na saĂșde fĂsica, na satisfação e na realização profissional. As anĂĄlises comparativas evidenciaram maiores problemas de stresse e reacçÔes mais negativas ao trabalho nas mulheres, nos enfermeiros mais novos e com menor experiĂȘncia, nos trabalhadores com contratos a prazo, nos profissionais que realizam trabalho por turnos e nos que trabalham mais horas.This work analyses occupational stress in 286 nurses from hospitals and health care centres in Portugal. The
following dimensions were evaluated: stress, burnout, physical health problems, satisfaction and professional fulfilment.
Results revealed significant stress experiences in 30% of the professionals, and emotional exhaustion problems in 15%.
Multiple regression analysis pointed out stress as an important predictor of emotional exhaustion, physical health, satisfaction
and professional fulfilment. Comparative analysis suggested more occupational stress and professional negative experiences
in the following groups: female nurses, younger and less experienced nurses, those with short-term working contracts, nurses
working on a shift-basis system, and nurses working during long hours.(undefined
Predição de ganhos genĂ©ticos por Ăndices de seleção na população de milho pipoca UNB-2U sob seleção recorrente
Multiwavelength studies of MHD waves in the solar chromosphere: An overview of recent results
The chromosphere is a thin layer of the solar atmosphere that bridges the
relatively cool photosphere and the intensely heated transition region and
corona. Compressible and incompressible waves propagating through the
chromosphere can supply significant amounts of energy to the interface region
and corona. In recent years an abundance of high-resolution observations from
state-of-the-art facilities have provided new and exciting ways of
disentangling the characteristics of oscillatory phenomena propagating through
the dynamic chromosphere. Coupled with rapid advancements in
magnetohydrodynamic wave theory, we are now in an ideal position to thoroughly
investigate the role waves play in supplying energy to sustain chromospheric
and coronal heating. Here, we review the recent progress made in
characterising, categorising and interpreting oscillations manifesting in the
solar chromosphere, with an impetus placed on their intrinsic energetics.Comment: 48 pages, 25 figures, accepted into Space Science Review
Search for the lepton-flavor-violating decays Bs0âe±Όâ and B0âe±Όâ
A search for the lepton-flavor-violating decays Bs0âe±Όâ and B0âe±Όâ is performed with a data sample, corresponding to an integrated luminosity of 1.0ââfb-1 of pp collisions at âs=7ââTeV, collected by the LHCb experiment. The observed number of Bs0âe±Όâ and B0âe±Όâ candidates is consistent with background expectations. Upper limits on the branching fractions of both decays are determined to be B(Bs0âe±Όâ)101ââTeV/c2 and MLQ(B0âe±Όâ)>126ââTeV/c2 at 95% C.L., and are a factor of 2 higher than the previous bounds
A home and ambulatory artificial nutrition (NADYA) group report, home parenteral nutrition in Spain, 2013
Aim: to communicate the results of the Spanish Home Parenteral Nutrition (HPN) registry of the NADYA-SENPE group for the year 2013.
Material and methods: data was recorded online by NADYA group collaborators that were responsible of the HPN follow-up from 1st January to 31st December 2013.
Results: a total of 197 patients and 202 episodes of HPN were registered from 35 hospitals that represents a rate of 4,22 patients/million habitants/year 2013. The median age was 53 years (IQR 40 â 64) for 189 adult patients and 7 months (IQR 6 â 35,5) for children. The most frequent disease in adults was neoplasm (30,7%) followed by other diseases (20,1%) and mesenteric ischemia (12,7%). Short bowel syndrome and intestinal obstruction (25,9%) were in 35.7% cases the indications for HPN
Measurements of long-range near-side angular correlations in TeV proton-lead collisions in the forward region
Two-particle angular correlations are studied in proton-lead collisions at a
nucleon-nucleon centre-of-mass energy of TeV, collected
with the LHCb detector at the LHC. The analysis is based on data recorded in
two beam configurations, in which either the direction of the proton or that of
the lead ion is analysed. The correlations are measured in the laboratory
system as a function of relative pseudorapidity, , and relative
azimuthal angle, , for events in different classes of event
activity and for different bins of particle transverse momentum. In
high-activity events a long-range correlation on the near side, , is observed in the pseudorapidity range . This
measurement of long-range correlations on the near side in proton-lead
collisions extends previous observations into the forward region up to
. The correlation increases with growing event activity and is found
to be more pronounced in the direction of the lead beam. However, the
correlation in the direction of the lead and proton beams are found to be
compatible when comparing events with similar absolute activity in the
direction analysed.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2015-040.htm
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