36 research outputs found

    Performance Analysis in Off-design Condition of Gas Turbine Air-bottoming Combined System☆

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    Abstract Nowadays, the gradual depletion of fossil fuels associated with constraints on emissions of greenhouse gases leads to valorize their wasted heat from power plant. One of the technologies adopted for improvement is the utilization of combined cycles. For this purpose, the steam cycle is used most frequently. These systems are highly efficient, but they are very complex and water is requested, moreover they are very heavy, so they cannot always be used. In this context, Air Bottoming Cycles (ABC) become attractive for potential use in future plants and repowering because they are light, compact and they have flexible-use and no water consumption. An application of an Air Bottoming Cycle (ABC) is composed of a gas turbine powered by natural gas, an air compressor and an air turbine coupled to the system by means of a heat exchanger, referred to as the AHX (Air Heat Exchanger). The aim of this paper is to study an Air Bottoming Cycle (ABC) that uses a medium power industrial gas turbine as topper cycle. A thermodynamic optimization is realized, determining the best pressure ratio and air mass flow rate of bottomer cycle. Then, an off-design analysis varying ambient temperature and FAR (Fuel Air Ratio) is shown, in fact, in this case, the exhaust gas conditions from topper gas turbine and inlet air of bottoming joule cycle change

    On-Farm Mortality in Cattle

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    The present study was aimed at exploring if and on what extent on-farm mortality, which is regularly notified in national cattle databases in the EU, could be used to design an early warning system for emerging diseases in cattle. The statistical analysis of mortality rates recorded in Italy in 2008 showed a clear influence by transport, age, sex and season. Through spatial and spatio-clustering methods several geographic area with exceptionally high mortality rates were detected. A more in-dept analysis of individual causes of mortality in the Provinces of Trento and Bolzano showed that on-farm mortality was greatly influenced by management practices and economic conditions. In order to control some of the influencing management factors a model was created to compare for a given population the actual and expected mortality rates. A conclusion of the study was that on-farm mortality regularly notified in national livestock databases could represent an important indicator for evaluating herd management practices. Further analysis and refinement of the applied models would be needed in order to establish a robust method for the detection of anomalous events with respect to the outbreak of animal diseasesJRC.DG.G.7-Traceability and vulnerability assessmen

    Three-row versus two-row circular staplers for left-sided colorectal anastomosis: a propensity score-matched analysis of the iCral 2 and 3 prospective cohorts

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    Background: Since most anastomoses after left-sided colorectal resections are performed with a circular stapler, any technological change in stapling devices may influence the incidence of anastomotic adverse events. The aim of the present study was to analyze the effect of a three-row circular stapler on anastomotic leakage and related morbidity after left-sided colorectal resections. Materials and methods: A circular stapled anastomosis was performed in 4255 (50.9%) out of 8359 patients enrolled in two prospective multicenter studies in Italy, and, after exclusion criteria to reduce heterogeneity, 2799 (65.8%) cases were retrospectively analyzed through a 1:1 propensity score-matching model including 20 covariates relative to patient characteristics, to surgery and to perioperative management. Two well-balanced groups of 425 patients each were obtained: group (A) – true population of interest, anastomosis performed with a three-row circular stapler; group (B) – control population, anastomosis performed with a two-row circular stapler. The target of inferences was the average treatment effect in the treated (ATT). The primary endpoints were overall and major anastomotic leakage and overall anastomotic bleeding; the secondary endpoints were overall and major morbidity and mortality rates. The results of multiple logistic regression analyses for the outcomes, including the 20 covariates selected for matching, were presented as odds ratios (OR) and 95% confidence intervals (95% CI). Results: Group A versus group B showed a significantly lower risk of overall anastomotic leakage (2.1 vs. 6.1%; OR 0.33; 95% CI 0.15–0.73; P = 0.006), major anastomotic leakage (2.1 vs. 5.2%; OR 0.39; 95% CI 0.17–0.87; P = 0.022), and major morbidity (3.5 vs. 6.6% events; OR 0.47; 95% CI 0.24–0.91; P = 0.026). Conclusion: The use of three-row circular staplers independently reduced the risk of anastomotic leakage and related morbidity after left-sided colorectal resection. Twenty-five patients were required to avoid one leakage

    Evolving trends in the management of acute appendicitis during COVID-19 waves. The ACIE appy II study

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    Background: In 2020, ACIE Appy study showed that COVID-19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non-operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak. Methods: From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS-CoV-2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study. Results: A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM. Conclusion: Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS-COV-2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide

    Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

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    Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

    Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

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    This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

    Abstracts from the Food Allergy and Anaphylaxis Meeting 2016

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    Granular cell tumours of the oesophagus and larynx

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    Teams of Robots for Underwater Archaeology: the ARROWS project

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    ARROWS is the acronym for Archaeological RObot systems for the World’s Seas. The project, started in September 2012, is funded by the EU in the framework of the FP7 call ENV-2012, challenge 6.2-6, devoted to “Development of advanced technologies and tools for mapping, diagnosing, excavating, and securing underwater and coastal archaeological sites”. The ARROWS consortium comprises expertise from underwater archaeology, underwater engineering, robotics, image processing and recognition from academia and industry. 10 partners from 5 different Countries are involved
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