304 research outputs found
Lifetime Maximization for Amplify-and-Forward Cooperative Networks
[[abstract]]Power allocation strategies are devised to maximize the network lifetime of amplify-and-forward (AF) cooperative networks. We consider the scenario where one source and multiple partners cooperate to transmit messages to the destination. The powers emitted by the users are subject to the SNR requirement at the destination. First, the power allocation strategy that demands the minimum instantaneous aggregate transmit power of all cooperating partners is described and analyzed. The optimal solution results in a form of selective relaying; namely, the user with the best channel condition is selected to help in relaying the message. However, this instantaneous power minimization strategy does not necessarily maximize the lifetime of battery-limited systems. Then, we propose three AF cooperative schemes to exploit the channel state information (CSI), the residual battery energy and the QoS requirement. It is shown that the network lifetime can be extended considerably by taking all these three factors into account.[[fileno]]2030137030021[[department]]éťćŠĺˇĽç¨ĺ¸
Two-level system with a thermally fluctuating transfer matrix element: Application to the problem of DNA charge transfer
Charge transfer along the base-pair stack in DNA is modeled in terms of
thermally-assisted tunneling between adjacent base pairs. Central to our
approach is the notion that tunneling between fluctuating pairs is rate-limited
by the requirement of their optimal alignment. We focus on this aspect of the
process by modeling two adjacent base pairs in terms of a classical damped
oscillator subject to thermal fluctuations as described by a Fokker-Planck
equation. We find that the process is characterized by two time scales, a
result that is in accord with experimental findings.Comment: original file is revtex4, 10 pages, three eps figure
A first-principles approach to electrical transport in atomic-scale nanostructures
We present a first-principles numerical implementation of Landauer formalism
for electrical transport in nanostructures characterized down to the atomic
level. The novelty and interest of our method lies essentially on two facts.
First of all, it makes use of the versatile Gaussian98 code, which is widely
used within the quantum chemistry community. Secondly, it incorporates the
semi-infinite electrodes in a very generic and efficient way by means of Bethe
lattices. We name this method the Gaussian Embedded Cluster Method (GECM). In
order to make contact with other proposed implementations, we illustrate our
technique by calculating the conductance in some well-studied systems such as
metallic (Al and Au) nanocontacts and C-atom chains connected to metallic (Al
and Au) electrodes. In the case of Al nanocontacts the conductance turns out to
be quite dependent on the detailed atomic arrangement. On the contrary, the
conductance in Au nanocontacts presents quite universal features. In the case
of C chains, where the self-consistency guarantees the local charge transfer
and the correct alignment of the molecular and electrode levels, we find that
the conductance oscillates with the number of atoms in the chain regardless of
the type of electrode. However, for short chains and Al electrodes the even-odd
periodicity is reversed at equilibrium bond distances.Comment: 14 pages, two-column format, submitted to PR
Vortex Lattice Melting into Disentangled Liquid Followed by the 3D-2D Decoupling Transition in YBa_2Cu_4O_8 Single Crystals
A sharp resistance drop associated with vortex lattice melting was observed
in high quality YBa_2Cu_4O_8 single crystals. The melting line is well
described well by the anisotropic GL theory. Two thermally activated flux flow
regions, which were separated by a crossover line B_cr=1406.5(1-T/T_c)/T
(T_c=79.0 K, B_cr in T), were observed in the vortex liquid phase. Activation
energy for each region was obtained and the corresponding dissipation mechanism
was discussed. Our results suggest that the vortex lattice in YBa_2Cu_4O_8
single crystal melts into disentangled liquid, which then undergoes a 3D-2D
decoupling transition.Comment: 5 pages, 4 eps figures, RevTex (Latex2.09
Genetic clustering on the hippocampal surface for genome-wide association studies
Imaging genetics aims to discover how variants in the human genome influence brain measures derived from images. Genome-wide association scans (GWAS) can screen the genome for common differences in our DNA that relate to brain measures. In small samples, GWAS has low power as individual gene effects are weak and one must also correct for multiple comparisons across the genome and the image. Here we extend recent work on genetic clustering of images, to analyze surface-based models of anatomy using GWAS. We performed spherical harmonic analysis of hippocampal surfaces, automatically extracted from brain MRI scans of 1254 subjects. We clustered hippocampal surface regions with common genetic influences by examining genetic correlations (rg) between the normalized deformation values at all pairs of surface points. Using genetic correlations to cluster surface measures, we were able to boost effect sizes for genetic associations, compared to clustering with traditional phenotypic correlations using Pearson's r
Temporal changes in the gut microbiota in farmed Atlantic cod (Gadus morhua) outweigh the response to diet supplementation with macroalgae
Background:
Aquaculture successfully meets global food demands for many fish species. However, aquaculture production of Atlantic cod (Gadus morhua) is just 2.5% of total market production. For cod farming to be a viable economic venture specific challenges on how to increase growth, health and farming productivity need to be addressed. Feed ingredients play a key role here. Macroalgae (seaweeds) have been suggested as a functional feed supplement with both health and economic benefits for terrestrial farmed animals and fish. The impact of such dietary supplements to cod gut integrity and microbiota, which contribute to overall fish robustness is unknown. The objective of this study was to supplement the diet of juvenile Atlantic cod with macroalgae and determine the impacts on fish condition and growth, gut morphology and hindgut microbiota composition (16S rRNA amplicon sequencing). Fish were fed one of three diets: control (no macroalgal inclusion), 10% inclusion of either egg wrack (Ascophyllum nodosum) or sea lettuce (Ulva rigida) macroalgae in a 12-week trial.
Results:
The results demonstrated there was no significant difference in fish condition, gut morphology or hindgut microbiota between the U. rigida supplemented fish group and the control group at any time-point. This trend was not observed with the A. nodosum treatment. Fish within this group were further categorised as either âNormalâ or âLower Growthâ. âLower Growthâ individuals found the diet unpalatable resulting in reduced weight and condition factor combined with an altered gut morphology and microbiome relative to the other treatments. Excluding this group, our results show that the hindgut microbiota was largely driven by temporal pressures with the microbial communities becoming more similar over time irrespective of dietary treatment. The core microbiome at the final time-point consisted of the orders Vibrionales (Vibrio and Photobacterium), Bacteroidales (Bacteroidetes and Macellibacteroides) and Clostridiales (Lachnoclostridium).
Conclusions:
Our study indicates that U. rigida macroalgae can be supplemented at 10% inclusion levels in the diet of juvenile farmed Atlantic cod without any impact on fish condition or hindgut microbial community structure. We also conclude that 10% dietary inclusion of A. nodosum is not a suitable feed supplement in a farmed cod diet
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types
Search for a W' boson decaying to a bottom quark and a top quark in pp collisions at sqrt(s) = 7 TeV
Results are presented from a search for a W' boson using a dataset
corresponding to 5.0 inverse femtobarns of integrated luminosity collected
during 2011 by the CMS experiment at the LHC in pp collisions at sqrt(s)=7 TeV.
The W' boson is modeled as a heavy W boson, but different scenarios for the
couplings to fermions are considered, involving both left-handed and
right-handed chiral projections of the fermions, as well as an arbitrary
mixture of the two. The search is performed in the decay channel W' to t b,
leading to a final state signature with a single lepton (e, mu), missing
transverse energy, and jets, at least one of which is tagged as a b-jet. A W'
boson that couples to fermions with the same coupling constant as the W, but to
the right-handed rather than left-handed chiral projections, is excluded for
masses below 1.85 TeV at the 95% confidence level. For the first time using LHC
data, constraints on the W' gauge coupling for a set of left- and right-handed
coupling combinations have been placed. These results represent a significant
improvement over previously published limits.Comment: Submitted to Physics Letters B. Replaced with version publishe
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