562 research outputs found
"Learning to live with what you can't rise above": control beliefs, symptom control, and adjustment to tinnitus.
The relations between 3 types of perceived control, symptom severity, and 2 adaptational outcomes, depressive symptoms and psychological well-being, were examined in a sample of 319 people with tinnitus. Consistent with previous studies of control and adjustment to chronic health conditions, general health and symptom control were associated with better psychological adjustment, and retrospective control was associated with worse psychological adjustment. Only symptom control emerged as a significant moderator in the symptom severity-adjustment relationship, such that stronger beliefs in one's ability to control symptoms were most strongly associated with better adjustment among those with more severe tinnitus symptoms. These findings were consistent with coping perspectives and cognitive adaptation theory and suggest that symptom-related perceptions of control may be an effective coping resource to nurture in chronic health contexts with severe symptoms
Genetic diversity within and between British and Irish breeds: the maternal and paternal history of native ponies.
The UK and Ireland have many native pony breeds with historical and cultural importance as well as being a source of uncharacterized genetic diversity. However, there is a lack of comprehensive research investigating their genetic diversity and phylogenetic interrelationships. Many studies contain a limited number of pony breeds or small sample sizes for these breeds. This may result in erroneous grouping of pony breeds that otherwise have intricate interrelationships with each other and are not evaluated correctly when placed as a token subset of a larger dataset. This is the first study that specifically investigates the genetic diversity within and between British and Irish native pony breeds using large sample numbers from locations of their native origin. This study used a panel of microsatellite markers and sequence analysis of the mitochondrial control region to analyze the genetic diversity within and between 11 pony breeds from Britain and Ireland. A large dataset was collected (a total of 485 animals were used for mtDNA analysis and 450 for microsatellite analysis), and previously published data were used to place the British and Irish ponies in a global context. The native ponies of Britain and Ireland were found to have had a complex history, and the interrelationships between the breeds were revealed. Overall, high levels of genetic diversity were maintained in native breeds, although some reduction was evident in small or isolated populations (Shetland, Carneddau, and Section C). Unusual mitochondrial diversity distribution patterns were apparent for the Carneddau and Dartmoor, although among breeds and global haplogroups there was a high degree of haplotype sharing evident, well-represented within British and Irish ponies. Ancestral maternal diversity was maintained by most populations, particularly the Fells and Welsh ponies, which exhibited rare and ancient lineages. The maternal and paternal histories of the breeds are distinct, with male-biased crossings between native breeds, and other shared influences, likely Arabs and Thoroughbreds, are apparent. The data generated herein provide valuable information to guide and implement the conservation of increasingly rare native genetic resources
Kinetic model of II-VI(001) semiconductor surfaces: Growth rates in atomic layer epitaxy
We present a zinc-blende lattice gas model of II-VI(001) surfaces, which is
investigated by means of Kinetic Monte Carlo (KMC) simulations. Anisotropic
effective interactions between surface metal atoms allow for the description
of, e.g., the sublimation of CdTe(001), including the reconstruction of
Cd-terminated surfaces and its dependence on the substrate temperature T. Our
model also includes Te-dimerization and the potential presence of excess Te in
a reservoir of weakly bound atoms at the surface. We study the self-regulation
of atomic layer epitaxy (ALE) and demonstrate how the interplay of the
reservoir occupation with the surface kinetics results in two different
regimes: at high T the growth rate is limited to 0.5 layers per ALE cycle,
whereas at low enough T each cycle adds a complete layer of CdTe. The
transition between the two regimes occurs at a characteristic temperature and
its dependence on external parameters is studied. Comparing the temperature
dependence of the ALE growth rate in our model with experimental results for
CdTe we find qualitative agreement.Comment: 9 pages (REVTeX), 8 figures (EPS). Content revised, references added,
typos correcte
Characteristic cohomology of -form gauge theories
The characteristic cohomology for an arbitrary set of free
-form gauge fields is explicitly worked out in all form degrees ,
where is the spacetime dimension. It is shown that this cohomology is
finite-dimensional and completely generated by the forms dual to the field
strengths. The gauge invariant characteristic cohomology is also computed. The
results are extended to interacting -form gauge theories with gauge
invariant interactions. Implications for the BRST cohomology are mentioned.Comment: Latex file, no figures, 44 page
The institutional shaping of management: in the tracks of English individualism
Globalisation raises important questions about the shaping of economic action by cultural factors. This article explores the formation of what is seen by some as a prime influence on the formation of British management: individualism. Drawing on a range of historical sources, it argues for a comparative approach. In this case, the primary comparison drawn is between England and Scotland. The contention is that there is a systemic approach to authority in Scotland that can be contrasted to a personal approach in England. An examination of the careers of a number of Scottish pioneers of management suggests the roots of this systemic approach in practices of church governance. Ultimately this systemic approach was to take a secondary role to the personal approach engendered by institutions like the universities of Oxford and Cambridge, but it found more success in the different institutional context of the USA. The complexities of dealing with historical evidence are stressed, as is the value of taking a comparative approach. In this case this indicates a need to take religious practice as seriously as religious belief as a source of transferable practice. The article suggests that management should not be seen as a simple response to economic imperatives, but as shaped by the social and cultural context from which it emerges
Pre-M Phase-promoting Factor Associates with Annulate Lamellae in Xenopus Oocytes and Egg Extracts
We have used complementary biochemical and in vivo approaches to study the compartmentalization of M phase-promoting factor (MPF) in prophase Xenopus eggs and oocytes. We first examined the distribution of MPF (Cdc2/CyclinB2) and membranous organelles in high-speed extracts of Xenopus eggs made during mitotic prophase. These extracts were found to lack mitochondria, Golgi membranes, and most endoplasmic reticulum (ER) but to contain the bulk of the pre-MPF pool. This pre-MPF could be pelleted by further centrifugation along with components necessary to activate it. On activation, Cdc2/CyclinB2 moved into the soluble fraction. Electron microscopy and Western blot analysis showed that the pre-MPF pellet contained a specific ER subdomain comprising "annulate lamellae" (AL): stacked ER membranes highly enriched in nuclear pores. Colocalization of pre-MPF with AL was demonstrated by anti-CyclinB2 immunofluorescence in prophase oocytes, in which AL are positioned close to the vegetal surface. Green fluorescent protein-CyclinB2 expressed in oocytes also localized at AL. These data suggest that inactive MPF associates with nuclear envelope components just before activation. This association may explain why nuclei and centrosomes stimulate MPF activation and provide a mechanism for targeting of MPF to some of its key substrates
Two-dimensional Quantum-Corrected Eternal Black Hole
The one-loop quantum corrections to geometry and thermodynamics of black hole
are studied for the two-dimensional RST model. We chose boundary conditions
corresponding to the eternal black hole being in the thermal equilibrium with
the Hawking radiation. The equations of motion are exactly integrated. The one
of the solutions obtained is the constant curvature space-time with dilaton
being a constant function. Such a solution is absent in the classical theory.
On the other hand, we derive the quantum-corrected metric (\ref{solution})
written in the Schwarzschild like form which is a deformation of the classical
black hole solution \cite{5d}. The space-time singularity occurs to be milder
than in classics and the solution admits two asymptotically flat black hole
space-times lying at "different sides" of the singularity. The thermodynamics
of the classical black hole and its quantum counterpart is formulated. The
thermodynamical quantities (energy, temperature, entropy) are calculated and
occur to be the same for both the classical and quantum-corrected black holes.
So, no quantum corrections to thermodynamics are observed. The possible
relevance of the results obtained to the four-dimensional case is discussed.Comment: Latex, 28 pges; minor corrections in text and abstract made and new
references adde
Structure–activity Relationships of Amyloid Beta-aggregation Inhibitors Based on Curcumin: Influence of Linker Length and Flexibility
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66293/1/j.1747-0285.2007.00557.x.pd
Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS
We present the results of a search for new, heavy particles that decay at a
significant distance from their production point into a final state containing
charged hadrons in association with a high-momentum muon. The search is
conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV
and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS
detector operating at the Large Hadron Collider. Production of such particles
is expected in various scenarios of physics beyond the standard model. We
observe no signal and place limits on the production cross-section of
supersymmetric particles in an R-parity-violating scenario as a function of the
neutralino lifetime. Limits are presented for different squark and neutralino
masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final
version to appear in Physics Letters
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