An Investigation into how Non-native Language Patterns Shape the Relationship Between Immigrants and Host Country Natives

Although social psychologists have made important strides towards understanding the effects of stigma on both individuals’ behaviours and their relationships with non-stigmatized groups, language patterns within this domain have largely been ignored. This thesis aims to address this gap by investigating the role that language patterns play in shaping the relationship between native and non-native speakers against the backdrop of an increasingly relevant context in which communicators with diverse language backgrounds interact: Immigration. Drawing on both communication accommodation theory (CAT) and intergroup contact theory, I investigate the processes by which language styles influence perceptions of both individuals and the groups they represent, as well as attempt to determine how language-based categorizations affect those whose language style deviates from majority group norms. Across six studies, I take the perspective of native speakers and demonstrate that perceptions of communicators based on their language are not uniform but are determined by factors including the style of language used and the speaker’s background. I then take the perspective of non-native speakers and, across two studies, show that negative perceptions of non-native accents can result in poorer interactions with the native speaking out-group as well as a reduced ability to comprehend and communicate in the host country’s language. In sum, the eight studies presented in this thesis demonstrate that perceptions related to one’s style of language can be detrimental to the relationship between native and non-native speakers and by extension host country natives and immigrants. Theoretical and practical implications are discussed.University of Exete

Where Are You From? An Investigation into the Intersectionality of Accent Strength and Nationality Status on Perceptions of Non-native Speakers in Britain

We explore how interpersonal and intergroup perceptions are affected by a non-native speaker’s accent strength and the status of their home country. When nationality information was absent (Study 1), natives who heard a strong (vs. weak) accent rated the speaker as warmer but immigrants as a group as more threatening. This result was replicated when the speaker’s nationality was familiar (Study 2) but in this study, country status further shaped accent-based perceptions: the strong (vs. weak) accented speaker evoked more positive interpersonal perceptions when her country status was low, but more negative intergroup perceptions when her country status was high. When the status of the speaker’s nationality was manipulated (Study 3), we replicated the interpersonal perceptions found in Study 1 and the intergroup perceptions found in Study 2. Findings support a holistic approach to investigating perceptions of non-native speakers: one that considers nationality as well as accent strength

Prologue: Language Challenges in the 21st Century

As immigration and mobility increases, so do interactions between people from different linguistic backgrounds. Yet while linguistic diversity offers many benefits, it also comes with a number of challenges. In seven empirical articles and one commentary, this Special Issue addresses some of the most significant language challenges facing researchers in the 21st century: the power language has to form and perpetuate stereotypes, the contribution language makes to intersectional identities, and the role of language in shaping intergroup relations. By presenting work that aims to shed light on some of these issues, the goal of this Special Issue is to (a) highlight language as integral to social processes and (b) inspire researchers to address the challenges we face. To keep pace with the world’s constantly evolving linguistic landscape, it is essential that we make progress toward harnessing language’s power in ways that benefit 21st century globalized societies

Engaged followership and toxic science : exploring the effect of prototypicality on willingness to follow harmful experimental instructions

Funding: This research was supported by Economic and Social Research Council grant (ES/L003104/1), a Fellowship from the Australian Research Council (FL110100199), from funding received from the School of Management at the University of St Andrews.Drawing on the ‘engaged followership’ reinterpretation of Milgram’s work on obedience, four studies (three of which were pre-registered) examine the extent to which people’s willingness to follow an experimenter’s instructions is dependent on the perceived prototypicality of the science they are supposedly advancing. In Studies 1, 2 and 3, participants took part in a study that was described as advancing either ‘hard’ (prototypical) science (i.e., neuroscience) or ‘soft’ (non-prototypical) science (i.e., social science) before completing an online analogue of Milgram’s ‘Obedience to Authority’ paradigm. In Studies 1 and 2, participants in the neuroscience condition completed more trials than those in the social science condition. This effect was not replicated in Study 3, possibly because the timing of data collection (late 2020) coincided with an emphasis on social science’s importance in controlling COVID-19. Results of a final cross-sectional study (Study 4) indicated that participants who perceived the study as to be more prototypical of science found it more worthwhile, reported making a wider contribution by taking part, reported less dislike for the task, more happiness at having taken part, and more trust in the researchers, all of which indirectly predicted greater followership. Implications for the theoretical understanding of obedience to the toxic instructions of an authority are discussed.Publisher PDFPeer reviewe

Questioning authority: New perspectives on Milgram’s ‘obedience’ research and its implications for intergroup relations

Traditionally, Milgram's 'obedience' studies have been used to propose that 'ordinary people' are capable of inflicting great harm on outgroup members because they are predisposed to follow orders. According to this account, people focus so much on being good followers that they become unaware of the consequences of their actions. Atrocity is thus seen to derive from inattention. However recent work in psychology, together with historical reassessments of Nazi perpetrators, questions this analysis. In particular, forensic re-examination of Milgram's own findings, allied to new psychological and historical research, supports an “engaged follower” analysis in which the behaviour of perpetrators is understood to derive from identification with, and commitment to, an ingroup cause that is believed to be noble and worthwhile

Participant Concerns for the Learner in a Virtual Reality Replication of the Milgram Obedience Study

In Milgram’s seminal obedience studies, participants’ behaviour has traditionally been explained as a demonstration of people’s tendency to enter into an ‘agentic state’ when in the presence of an authority figure: they attend only to the demands of that authority and are insensitive to the plight of their victims. There have been many criticisms of this view, but most rely on either indirect or anecdotal evidence. In this study, participants (n = 40) are taken through a Virtual Reality simulation of the Milgram paradigm. Compared to control participants (n = 20) who are not taken through the simulation, those in the experimental conditions are found to attempt to help the Learner more by putting greater emphasis on the correct word over the incorrect words. We also manipulate the extent to which participants identify with the science of the study and show that high identifiers both give more help, are less stressed, and are more hesitant to press the shock button than low identifiers. We conclude that these findings constitute a refutation of the ‘agentic state’ approach to obedience. Instead, we discuss implications for the alternative approaches such as ‘engaged followership’ which suggests that obedience is a function of relative identification with the science and with the victim in the study. Finally, we discuss the value of Virtual Reality as a technique for investigating hard-to-study psychological phenomena

Engaged followership and toxic science: Exploring the effect of prototypicality on willingness to follow harmful experimental instructions

Drawing on the ‘engaged followership’ reinterpretation of Milgram’s work on obedience, four studies (three of which were pre-registered) examine the extent to which people’s willingness to follow an experimenter’s instructions is dependent on the perceived prototypicality of the science they are supposedly advancing. In Studies 1, 2 and 3, participants took part in a study that was described as advancing either ‘hard’ (prototypical) science (i.e., neuroscience) or ‘soft’ (non-prototypical) science (i.e., social science) before completing an online analogue of Milgram’s ‘Obedience to Authority’ paradigm. In Studies 1 and 2, participants in the neuroscience condition completed more trials than those in the social science condition. This effect was not replicated in Study 3, possibly because the timing of data collection (late 2020) coincided with an emphasis on social science’s importance in controlling COVID-19. Results of a final cross-sectional study (Study 4) indicated that participants who perceived the study to be more prototypical of science found it more worthwhile, reported making a wider contribution by taking part, reported less dislike for the task, more happiness at having taken part, and more trust in the researchers, all of which indirectly predicted greater followership. Implications for the theoretical understanding of obedience to the toxic instructions of an authority are discussed

REST Regulates Distinct Transcriptional Networks in Embryonic and Neural Stem Cells

The maintenance of pluripotency and specification of cellular lineages during embryonic development are controlled by transcriptional regulatory networks, which coordinate specific sets of genes through both activation and repression. The transcriptional repressor RE1-silencing transcription factor (REST) plays important but distinct regulatory roles in embryonic (ESC) and neural (NSC) stem cells. We investigated how these distinct biological roles are effected at a genomic level. We present integrated, comparative genome- and transcriptome-wide analyses of transcriptional networks governed by REST in mouse ESC and NSC. The REST recruitment profile has dual components: a developmentally independent core that is common to ESC, NSC, and differentiated cells; and a large, ESC-specific set of target genes. In ESC, the REST regulatory network is highly integrated into that of pluripotency factors Oct4-Sox2-Nanog. We propose that an extensive, pluripotency-specific recruitment profile lends REST a key role in the maintenance of the ESC phenotype

A Common Variant Associated with Dyslexia Reduces Expression of the KIAA0319 Gene

Numerous genetic association studies have implicated the KIAA0319 gene on human chromosome 6p22 in dyslexia susceptibility. The causative variant(s) remains unknown but may modulate gene expression, given that (1) a dyslexia-associated haplotype has been implicated in the reduced expression of KIAA0319, and (2) the strongest association has been found for the region spanning exon 1 of KIAA0319. Here, we test the hypothesis that variant(s) responsible for reduced KIAA0319 expression resides on the risk haplotype close to the gene's transcription start site. We identified seven single-nucleotide polymorphisms on the risk haplotype immediately upstream of KIAA0319 and determined that three of these are strongly associated with multiple reading-related traits. Using luciferase-expressing constructs containing the KIAA0319 upstream region, we characterized the minimal promoter and additional putative transcriptional regulator regions. This revealed that the minor allele of rs9461045, which shows the strongest association with dyslexia in our sample (max p-value = 0.0001), confers reduced luciferase expression in both neuronal and non-neuronal cell lines. Additionally, we found that the presence of this rs9461045 dyslexia-associated allele creates a nuclear protein-binding site, likely for the transcriptional silencer OCT-1. Knocking down OCT-1 expression in the neuronal cell line SHSY5Y using an siRNA restores KIAA0319 expression from the risk haplotype to nearly that seen from the non-risk haplotype. Our study thus pinpoints a common variant as altering the function of a dyslexia candidate gene and provides an illustrative example of the strategic approach needed to dissect the molecular basis of complex genetic traits

GA4GH: International policies and standards for data sharing across genomic research and healthcare.

The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches. The decreasing cost of genomic sequencing (along with other genome-wide molecular assays) and increasing evidence of its clinical utility will soon drive the generation of sequence data from tens of millions of humans, with increasing levels of diversity. In this perspective, we present the GA4GH strategies for addressing the major challenges of this data revolution. We describe the GA4GH organization, which is fueled by the development efforts of eight Work Streams and informed by the needs of 24 Driver Projects and other key stakeholders. We present the GA4GH suite of secure, interoperable technical standards and policy frameworks and review the current status of standards, their relevance to key domains of research and clinical care, and future plans of GA4GH. Broad international participation in building, adopting, and deploying GA4GH standards and frameworks will catalyze an unprecedented effort in data sharing that will be critical to advancing genomic medicine and ensuring that all populations can access its benefits