182 research outputs found

    Capacidad de realizar esprints repetidos en jugadores profesionales de fĂștbol vs. FĂștbol sala

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    Objetivo: Investigar los cambios producidos ante acciones de esprines repetidos (20+20 metros con cambio de direcciĂłn ), el CMJ, la respuesta metabĂłlica (lactato) , y la relaciĂłn entre estas variables y la fuerza y resistencia en jugadores profesionales de fĂștbol y fĂștbol sala. MĂ©todos: Jugadores profesionales (n=30, doce de fĂștbol sala y veinte de fĂștbol) completaron tres sesiones de evaluaciĂłn; VO2max en tapiz rodante, el salto CMJ y la RM en sentadilla completa y finalmente, se realizĂł el test de RSA (6 x 40 (20+20)). Resultados: Se obtuvieron valores similares de fuerza en sentadilla, en CMJ, de LAC despuĂ©s de la prueba RSA y de VO2max ( 95,12 kg vs 94,73 kg ; 34,5 cm vs 35,9 cm ; 13,65 mmol vs 14,33 mmol ; 62,78 ml·kg·min-1 vs . 62,95 ml·kg·min-1 fĂștbol vs. fĂștbol sala, respectivamente). Se obtuvieron diferencias significativas cuando se analizĂł la pĂ©rdida de rendimiento en velocidad (total y entre los tres primeros y tres Ășltimos bloques de esprines) y en salto (2,67% vs 4,4%**; 1,28% vs 2,1%*; 2,88% vs 6,1%**; 9,71% vs 14,3%* de fĂștbol vs. fĂștbol sala, respectivamente). Conclusiones: Ambos deportes presentan diferencias significativas en las pĂ©rdidas de rendimiento en velocidad y salto a pesar de tener valores similares de fuerza, de VO2max, de lactato tras RSA y de CMJ. PodrĂ­a atribuirse a los esfuerzos propios de cada deporte y puede sugerir que deberĂ­a incrementarse el volumen de entrenamiento orientado a la capacidad de realizar esfuerzos repetidos frente a otro tipo de objetivo como la mejora de la capacidad aerĂłbica, sobre todo a nivel profesional.To investigate the changes through repeated explosive effort sequences (20+20-m sprint with change of direction), jumping, metabolic response (lactate), as well as the relationship between these variables and fitness qualities (strength and endurance) in professional futsal and soccer players. Methods: Male players (n =30, Twelve futsal and twenty soccer players) completed three testing sessions. In the first session was measured VO2max on a motorized treadmill. In the second session was measured counter movement jump (CMJ) and full squat RM in Smith Machine. Finally, in the third session six repeated-explosive effort sequences (RES) was performed. Results: Similar values of lower limbs strength, CMJ height, LAC after RSA test and VO2max (95,12 vs. 94,73; 34,5 vs. 35,9; 13,65 vs. 14,33; 62,78 vs. 62,95 soccer vs. futsal respectively) and significant differences when are analysed the loss of performance in velocity (total and between three first and three last) and vertical jump height (2,67 vs. 4,4**; 1,28 vs. 2,1*; 2,88 vs. 6,1**; 9,71 vs. 14,3* soccer vs. futsal respectively). Conclusions: Professional futsal and soccer obtain significant differences in speed and vertical jump height (CMJ) loss despite having similar values in squat, oxygen consumption, lactate after RSA test and CMJ height. Issue that could be attributed to the characteristics of the sport. This suggests that the volume should be increased oriented ability to perform repeated sprint actions over other type of training aimed at improving aerobic capacity especially at professional level.peerReviewe

    ContribuciĂłn al conocimiento de la flora de AndalucĂ­a: citas novedosas e interesantes de la provincia de AlmerĂ­a

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    Contribution to the knowledge about Andalusian flora: new and interesting cites of the Almería province.Palabras clave. Corología, Isla de Alborån, sureste ibérico, xenófitas.Key words. Corology, Alborån Island, South-Eastern Iberian Peninsula, xenophytes

    Modeling, Simulation and Control of Pedestrian Avoidance Maneuver for an Urban Electric Vehicle

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    In this paper, the mathematical model of an electric vehicle, as well as the control system for avoiding pedestrians in urban traffic is described. The vehicle is modeled as a continuous system consisting of several subsystems. The discrete model of several sensors and actuators, a decision system, and low-level controllers for acceleration/braking and steering systems are added. Based on this model, a pedestrian avoidance maneuver for typical speeds in city traffic is simulated. When the sensory system detects a pedestrian in the vehicle’s path, the decision system calculates its trajectory. Using this information, the speed and/or direction that the vehicle must take in order to avoid the accident are estimated. These values are sent to the low-level controllers of the accelerator/brake and steering, which generate the signals to be applied to such systems to achieve the desired trajectory and speed

    Surveillance and diagnostics of the emergent Sri Lankan cassava mosaic virus (Fam. Geminiviridae) in Southeast Asia

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    Emergent agricultural pathogens cause severe damage worldwide and their invasive potential is significantly increased by global trade, crop intensification and climate change. Standard surveillance and diagnostic protocols need to be evaluated and implemented, particularly with diseases caused by a wide range of pathogens that induce similar symptoms. Such is the case with Cassava Mosaic Disease (CMD) present in Africa and Asia, and associated with mixed virus infections and recombinant and re-assorted virus strains. CMD has been recently reported in Southeast Asia (SEA) and is already widely spread throughout this region. This communication offers an update on protocols and tools used to track the distribution of CMD and to characterize the pathogen associated with it in SEA

    APORTACIONES AL CATÁLOGO XENOFÍTICO DE LA PROVINCIA DE ALMERÍA (SURESTE IBÉRICO, ESPAÑA)

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    Se presentan 48 citas de 27 taxones asilvestrados en la provincia de AlmerĂ­a, entre las que se incluyen 9 novedades y 8 confirmaciones para la flora de la provincia de AlmerĂ­a, y que aportan nuevos datos interesantes sobre su potencial invasor (sobre la cual se discute)

    Hypoxia Negatively Regulates Antimetastatic PEDF in Melanoma Cells by a Hypoxia Inducible Factor-Independent, Autophagy Dependent Mechanism

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    Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor (SERPIN) superfamily, displays a potent antiangiogenic and antimetastatic activity in a broad range of tumor types. Melanocytes and low aggressive melanoma cells secrete high levels of PEDF, while its expression is lost in highly aggressive melanomas. PEDF efficiently abrogates a number of functional properties critical for the acquisition of metastatic ability by melanoma cells, such as neovascularization, proliferation, migration, invasiveness and extravasation. In this study, we identify hypoxia as a relevant negative regulator of PEDF in melanocytes and low aggressive melanoma cells. PEDF was regulated at the protein level. Importantly, although downregulation of PEDF was induced by inhibition of 2-oxoglutarate-dependent dioxygenases, it was independent of the hypoxia inducible factor (HIF), a key mediator of the adaptation to hypoxia. Decreased PEDF protein was not mediated by inhibition of translation through untranslated regions (UTRs) in melanoma cells. Degradation by metalloproteinases, implicated on PEDF degradation in retinal pigment epithelial cells, or by the proteasome, was also excluded as regulatory mechanism in melanoma cells. Instead, we found that degradation by autophagy was critical for PEDF downregulation under hypoxia in human melanoma cells. Our findings show that hypoxic conditions encountered during primary melanoma growth downregulate antiangiogenic and antimetastasic PEDF by a posttranslational mechanism involving degradation by autophagy and could therefore contribute to the acquisition of highly metastatic potential characteristic of aggressive melanoma cells

    Pancreatic metastases from renal cell carcinoma. Postoperative outcome after surgical treatment in a Spanish multicenter study (PANMEKID)

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    Background: Renal Cell Carcinoma (RCC) occasionally spreads to the pancreas. The purpose of our study is to evaluate the short and long-term results of a multicenter series in order to determine the effect of surgical treatment on the prognosis of these patients. Methods: Multicenter retrospective study of patients undergoing surgery for RCC pancreatic metastases, from January 2010 to May 2020. Variables related to the primary tumor, demographics, clinical characteristics of metastasis, location in the pancreas, type of pancreatic resection performed and data on short and long-term evolution after pancreatic resection were collected. Results: The study included 116 patients. The mean time between nephrectomy and pancreatic metastases' resection was 87.35 months (ICR: 1.51-332.55). Distal pancreatectomy was the most performed technique employed (50 %). Postoperative morbidity was observed in 60.9 % of cases (Clavien-Dindo greater than IIIa in 14 %). The median follow-up time was 43 months (13-78). Overall survival (OS) rates at 1, 3, and 5 years were 96 %, 88 %, and 83 %, respectively. The disease-free survival (DFS) rate at 1, 3, and 5 years was 73 %, 49 %, and 35 %, respectively. Significant prognostic factors of relapse were a disease free interval of less than 10 years (2.05 [1.13-3.72], p 0.02) and a history of previous extrapancreatic metastasis (2.44 [1.22-4.86], p 0.01). Conclusions: Pancreatic resection if metastatic RCC is found in the pancreas is warranted to achieve higher overall survival and disease-free survival, even if extrapancreatic metastases were previously removed. The existence of intrapancreatic multifocal compromise does not always warrant the performance of a total pancreatectomy in order to improve survival. (C) 2021 The Authors. Published by Elsevier Ltd
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