Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Content analysis : analyzing the Twitter usage of the Metropolitan Museum of Art, Tate Modern and Musee d’Orsay : how art museums connect with users over social media to increase communication and information exchange

Art museums rely on being able to reach audiences. In order to stay in the public eye, it is important for them to adopt various forms of social media. Twitter has proven to be an effective tool, as it is one of the most easy and accessible ways to reach a broader audience. This research answers the questions of how an art museum may utilize this social media tool in order to prompt a greater amount of user responses: likes and retweets of tweets. Coding 1,639 tweets produced by the Metropolitan Museum of Art (Met), Tate Modern, and Musee d’Orsay, the research studies what types of messages and add-on media forms are the most affective in garnering a response from followers on Twitter. The research shows that a museum will garner a greater amount of results if it produces educational tweets that include a photograph.Thesis (M.A.)Department of Journalis

Abundance, species richness and diversity of the orb-weaving spider families Araneidae, Nephilidae and Tetragnathidae in natural habitats in Trinidad, West Indies

Figure 1. Map of Trinidad showing the location of sampling localities of natural habitats.Published as part of Sewlal, Jo-Anne N. & Hailey, Adrian, 2016, Abundance, species richness and diversity of the orb-weaving spider families Araneidae, Nephilidae and Tetragnathidae in natural habitats in Trinidad, West Indies, pp. 1687-1698 in Journal of Natural History 50 on page 1689, DOI: 10.1080/00222933.2016.1156778, http://zenodo.org/record/399213

Conceptualising and Understanding Artistic Creativity in the Dementias: Interdisciplinary Approaches to Research and Practise

Creativity research has a substantial history in psychology and related disciplines; one component of this research tradition has specifically examined artistic creativity. Creativity theories have tended to concentrate, however, on creativity as an individual phenomenon that results in a novel production, and on cognitive aspects of creativity, often limiting its applicability to people with cognitive impairments, including those with a dementia. Despite growing indications that creativity is important for the wellbeing of people living with dementias, it is less well understood how creativity might be conceptualised, measured and recognised in this population, and how this understanding could influence research and practise. This paper begins by exploring prevailing concepts of creativity and assesses their relevance to dementia, followed by a critique of creativity and dementia research related to the arts. Perspectives from researchers, artists, formal and informal caregivers and those with a dementia are addressed. We then introduce several novel psychological and physiological approaches to better understand artistic-related creativity in this population and conclude with a conceptualisation of artistic creativity in the dementias to help guide future research and practise

Y-chromosomal haplotypes in domestic and wild goats reveal ancient paternal bottlenecks and recent introgressions

International audienc

Y-chromosomal haplotypes in domestic and wild goats reveal ancient paternal bottlenecks and recent introgressions

International audienc