9 research outputs found
Milk fatty acid profile of Holstein x Gyr cows on 'Marandu' grass pasture under different grazing strategies
O objetivo deste trabalho foi avaliar o perfil de ĂĄcidos graxos (AG) do leite de vacas Holandesas x Gir submetidos a dois tipos de manejo de pastejo (perĂodos de descanso fixo e variĂĄvel) de pastagem de Urochloa brizantha 'Marandu'. Utilizou-se o delineamento de blocos ao acaso, com duas repetiçÔes de ĂĄrea de pastagem (blocos) por tratamento e quatro vacas por bloco. A produção e a composição do leite nĂŁo foram influenciadas pelas estratĂ©gias de pastejo. NĂŁo houve efeito dos tratamentos sobre as proporçÔes (g 100 g-1 de AG totais) dos principais AG (palmĂtico, linoleico e α-linolĂȘnico) do pasto, mas suas ingestĂ”es (gramas por dia) foram influenciadas pelas diferenças de ingestĂŁo de matĂ©ria seca da forragem. As concentraçÔes dos AG no plasma e na gordura do leite nĂŁo foram influenciadas pelos tratamentos. As concentraçÔes dos ĂĄcidos rumĂȘnico, vacĂȘnico, oleico e α-linolĂȘnico na gordura do leite variaram de 0,71 a 0,93, 1,40 a 1,50, 19,40 a 19,70 e 0,39 a 0,43 g 100 g-1 de AG totais, respectivamente. As estratĂ©gias de pastejo de U. brizantha 'Marandu' nĂŁo alteram o perfil de ĂĄcidos graxos do leite das vacas.The objective of this work was to evaluate the milk fatty acid (FA) profile of Holstein x Gyr cows subjected to two different grazing managements (fixed and variable rest periods) of Urochloa brizantha 'Marandu' pastures. A randomized complete block design was used, with two replicates of pasture areas (blocks) per treatment and four cows per block. Milk production and composition were not affected by grazing strategies. No treatment effects were observed on the proportions (g 100 g-1 of total FA) of the main FAs (palmitic, linoleic, and α-linolenic) of the pasture, but their intakes (grams per day) were affected by differences in forage dry matter intake. The concentrations of FAs in milk plasma and fat were not affected by the treatments. Milk fat contents of rumenic, vaccenic, oleic, and α-linolenic acids varied from 0.71 to 0.93, 1.40 to 1.50, 19.40 to 19.70, and 0.39 to 0.43 g 100 g-1 total FAs, respectively. Grazing strategies of U. brizantha 'Marandu' cause no changes on the milk fatty acid profile of cows
Efeito do ambiente tĂ©rmico nas respostas fisiolĂłgicas, produtivas, caracterĂsticas do pelame e no comportamento de vacas holandesas puras por cruza no norte de Minas Gerais
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Previous issue date: 27Objetivou-se avaliar a interferĂȘncia das condiçÔes climĂĄticas do norte de Minas Gerais sobre as respostas fisiolĂłgicas e produtivas de vacas da raça Holandesa pura por cruza, em lactação. O experimento foi conduzido em duas fases, julho/agosto e outubro/novembro de 2010 utilizando 12 fĂȘmeas em lactação, totalizando 18 dias de avaliaçÔes em cada fase experimental. Os parĂąmetros fisiolĂłgicos como frequĂȘncia respiratĂłria (FR), temperatura retal (TR) e temperatura da superfĂcie do pelame (TPE) e os produtivos foram observados pela manhĂŁ e Ă tarde, durante trĂȘs dias da semana. JĂĄ a taxa de sudação foi medida uma vez por semana totalizando seis coletas em cada fase. Os dados climĂĄticos como temperatura ambiente (TBS), umidade relativa (UR), temperatura do ponto de orvalho (Tpo) foram coletados por intermĂ©dio de um sistema de aquisição de dados (datalogger), jĂĄ a temperatura do globo negro (Tgn) foi aferida com um termĂŽmetro de mercĂșrio. Essas variĂĄveis foram coletadas interna e externamente ao local onde os animais estavam alojados. As variĂĄveis fisiolĂłgicas apresentaram padrĂŁo sazonal bem claro, com maiores valores durante os meses mais quentes e menores nos meses mais frios. Mesmo com Ăndice de conforto tĂ©rmico acima de 80, nĂŁo foram evidenciados valores estressantes de temperatura retal, frequĂȘncia respiratĂłria e temperatura do pelame, mas ocorreu pequena redução na produção de leite nos meses mais quentes. Embora tenha havido efeito da fase experimental sobre os parĂąmetros estudados, os mesmos mantiveram-se dentro dos limites considerados normais para vacas Holandesas em lactação.The objective was to evaluate the influence of climatic conditions in northern Minas Gerais on the physiological and productive in Holstein cows by pure crosses, in lactation. The experiment was conducted in two phases, July / August and October / November 2010 using 12 lactating females, totaling 18 days of assessments in each phase. Physiological parameters such as respiratory rate (RR), rectal temperature (RT) and coat surface temperature (CST) and the production were observed in the morning and afternoon during the three days of the week. The rate of sweating was measured once a week totaling six samples in each phase. Climatic data such as temperature (DBT), relative humidity (RH), dew point temperature (Tpo) were collected by a datalogger, as the black globe temperature (BGT) was measured with a black globe thermometer, these variables were collected inside and outside the place where the animals were housed. Physiological variables showed clear seasonal pattern, with higher values during the warmer months and lower during the colder months. Even with thermal comfort index above 80, there was no evidence of stressful values for rectal temperature, respiratory rate and temperature of the coat, but there was a reduction in milk production in the warmer months. Although an effect of the experimental phase on the parameters studied, these remained within the normal range for lactating Holstein cows
INCIDĂNCIA DE BRUCELOSE ANIMAL NA REGIĂO SUL DE MINAS GERAIS EM REBANHOS POSITIVOS AO TESTE DO ANEL DO LEITE: NOTA TĂCNICA
Aiming to determining brucellosis prevalence in the south region of Minas Gerais, Brazil, 1396 cows, 15 horses and 13 dogs from 41 farms positive to the ring test were tested. The serological buffered acidified antigen (BAA), slow tube serum agglutination (STSA), and 2-mercapto ethanol (2-ME) tests were used. The brucellosis prevalence was 4.66%% in cows, 33.3% in horses and 0% in dogs. It is expected that the obtained data obtained are valuable to consolidate the deployment of the National Program for Control and Eradication of Brucellosis, according to official recommendations, in the southern region of Minas Gerais
Perfil sanitĂĄrio dos rebanhos caprinos e ovinos no Norte de Minas Gerais
The objective of this study was to evaluate the occurrence of infectious and contagious diseases inherds of sheep and goats in northern Minas Gerais State, Brazil. Visits were carried out to eighteenbreeders of sheep and goats, six visits in the region of Montes Claros, three in the core production ofFrancisco SĂĄ, two in JanaĂșba, two in Coração de Jesus and five IbiaĂ in the municipality, with fourcores in total production. The total number of animals in these properties was 2,052. Was carriedout through interviews, questionnaires to collect data on the occurrence of diseases and diarrheawas observed in young animals in 94.4% of the properties, caseous lymphadenitis in 88.9%, 33.3% inmastitis, foot pad dermatitis in 25.0%, conjunctivitis in 22.3%, contagious ecthyma in 11.1% and 5.55%in enterotoxemia. Only seven property held sporadic vaccination against clostridiosis. Practiceproper hygiene of premises and environments and handling young animals were not adopted.These figures are worrying, considering that the levels of occurrence of diseases was high. It is theneed for formation of a culture among producers that prophylactic measures should prevail on thehealing, because they represent higher costs and lower profit.O objetivo deste trabalho foi avaliar o perfil sanitĂĄrio em rebanhos de ovinos e caprinos no Nortede Minas Gerais. Foram realizadas visitas a dezoito criadores de ovinos e caprinos, sendo seis naregiĂŁo de Montes Claros, trĂȘs no nĂșcleo de produção de Francisco SĂĄ, duas em JanaĂșba, duasem Coração de Jesus e cinco no municĂpio de IbiaĂ, tendo no total quatro nĂșcleos de produção.O nĂșmero total de animais nestas propriedades era de 2052. Realizaram-se entrevistas atravĂ©sde questionĂĄrios para coleta de dados sobre a ocorrĂȘncia de doenças e observou-se diarrĂ©iaem animais jovens em 94,4% das propriedades, linfadenite caseosa em 88,9%, mastite em 33,3%,pododermatite em 25,0%, conjuntivite em 22,3%, ectima contagioso em 11,1% e enterotoxemia em5,55%. Apenas sete propriedades realizavam vacinação esporĂĄdica contra clostridiose. PrĂĄticascorretas de higienização das instalaçÔes e ambientes e manejo de crias nĂŁo eram adotadas. Estesdados sĂŁo preocupantes, considerando que os nĂveis de ocorrĂȘncia de enfermidades eram altos.Tem-se assim a necessidade de formação de uma cultura entre os produtores de que as medidasprofilĂĄticas devem prevalecer sobre as curativas, pois estas representam maior custo e menorlucro. Sanitary profile of the goat and sheep flocks in the North of Minas Gerais State,BrazilAbstractThe objective of this study was to evaluate the occurrence of infectious and contagious diseases inherds of sheep and goats in northern Minas Gerais State, Brazil. Visits were carried out to eighteenbreeders of sheep and goats, six visits in the region of Montes Claros, three in the core production ofFrancisco SĂĄ, two in JanaĂșba, two in Coração de Jesus and five IbiaĂ in the municipality, with fourcores in total production. The total number of animals in these properties was 2,052. Was carriedout through interviews, questionnaires to collect data on the occurrence of diseases and diarrheawas observed in young animals in 94.4% of the properties, caseous lymphadenitis in 88.9%, 33.3% inmastitis, foot pad dermatitis in 25.0%, conjunctivitis in 22.3%, contagious ecthyma in 11.1% and 5.55%in enterotoxemia. Only seven property held sporadic vaccination against clostridiosis. Practiceproper hygiene of premises and environments and handling young animals were not adopted.These figures are worrying, considering that the levels of occurrence of diseases was high. It is theneed for formation of a culture among producers that prophylactic measures should prevail on thehealing, because they represent higher costs and lower profit
Perfil de ĂĄcidos graxos do leite de vacas HolandĂȘs x Gir pastejando capim-marandu suplementado com concentrado contendo Ăłleo de girassol
The inclusion of plant oils in the diets of grazing cows represents a promising nutritional strategy for the production of milk naturally enriched with bioactive compounds, such as rumenic (cis-9, trans-11 CLA), vaccenic (trans-11 C18:1) and oleic (cis-9 C18:1) acids. The aim of this study was to evaluate the effect of dietary supplementation with sunflower oil (SO) on the fatty acid (FA) composition of milk from Holstein x Gyr dairy cows grazing on Urochloa brizantha cv. Marandu under rotational stocking. Sixteen multiparous cows with 185±10 days in milk received a concentrate containing 0% (control) or 15% SO on a dry matter basis in a randomized block design with two replications (paddocks). The results were analyzed with mixed models (P ? 0.05) using repeated measurements over time, as represented by sampling days 14, 35 and 62 (periods 1, 2 and 3, respectively). In any period, an effect of SO supplementation was observed on milk production, pasture dry matter intake and nutrients intake, whereas the concentrations of most milk FA were altered in SO-fed cows. In particular, dietary supplementation with SO resulted in the production of milk enriched with FA beneficial to human health (rumenic, vaccenic and oleic acids) and with lower levels of hypercholesterolemic lauric (C12:0), myristic (C14:0) and palmitic (C16:0) acids. This positive effect on the nutritional quality of milk fat was more noticeable from the 40th to 43rd days of sunflower oil supplementation.A inclusĂŁo de Ăłleos vegetais na dieta de vacas a pasto Ă© uma estratĂ©gia nutricional promissora para a produção de leite naturalmente enriquecido com ĂĄcidos graxos bioativos como o rumĂȘnico (CLA cis-9, trans-11), vacĂȘnico (C18:1 trans-11) e oleico (C18:1 cis-9). Objetivou-se avaliar o efeito da suplementação da dieta com Ăłleo de girassol sobre a composição de ĂĄcidos graxos do leite de vacas HolandĂȘs x Gir sob pastejo rotacionado em Urochloa brizantha cv. Marandu. Foram utilizadas 16 vacas multĂparas com 185±10 dias em lactação recebendo concentrado com 0% (controle) ou com 15% de inclusĂŁo de Ăłleo de girassol com base na matĂ©ria seca, em delineamento de blocos ao acaso, com duas repetiçÔes de ĂĄrea de pastagem. Os resultados foram analisados utilizando-se modelos mistos (P ? 0,05), com medidas repetidas no tempo, representadas pelos dias de amostragem 14, 35 e 62 (respectivamente, perĂodos 1, 2 e 3). A produção de leite e o consumo de matĂ©ria seca de pasto e de nutrientes nĂŁo foram afetados pela suplementação lipĂdica em nenhum dos perĂodos, mas houve efeito sobre os teores da maioria dos ĂĄcidos graxos do leite. A suplementação do pasto com Ăłleo de girassol permitiu produzir leite com maiores teores de ĂĄcidos graxos benĂ©ficos Ă saĂșde humana (rumĂȘnico, vacĂȘnico e oleico) e com menores teores dos ĂĄcidos graxos hipercolesterolĂȘmicos lĂĄurico (C12:0), mirĂstico (C14:0) e palmĂtico (C16:0). O efeito positivo na qualidade nutricional da gordura do leite foi mais pronunciado do 40o ao 43o dia de suplementação com Ăłleo de girassol
Caracterização do comportamento de vacas Holandesas em lactação confinadas em sistema Compost Barn em clima tropical
<p>O
comportamento do gado de leite pode ser afetado pelo tipo de sistema de criação.
O sistema <i>Compost Barn</i>(CB) para gado
de leite foi desenvolvido com o intuito de melhorar o conforto, a saĂșde e a
longevidade dos animais, e também facilitar as pråticas de manejo. O objetivo
deste estudo foi caracterizar o comportamento de vacas Holandesas em lactação
confinadas em sistema CB em clima tropical. Para isso, foram monitorados o
comportamento de 33 vacas em lactação no perĂodo de inverno e 31 no perĂodo de
verĂŁo. Os registros dos comportamentos foram obtidos a cada 15 minutos, durante
48 horas, com interrupção nos perĂodos de ordenhas e nos horĂĄrios de
revolvimento da cama. Os comportamentos registrados foram: em pé ruminando
(EPR), em pé em ócio (EPO), em pé comendo (EPC), deitada em ócio (DO) ou
deitada ruminando (DR). Durante o perĂodo de
verĂŁo a mĂ©dia de permanĂȘncia dos animais em repouso foi compatĂvel com o
esperado para vacas de alta produção. O tempo de permanĂȘncia dos animais na
espera para ordenha e para a realização do revolvimento da cama do sistema,
ultrapassou 3,5 horas/dia. Portanto, as vacas em lactação alojadas em sistema CBem
clima tropical apresentaram comportamentos condizentes com o natural. O
bioclima no sistema CB, mesmo no perĂodo de verĂŁo, apresentou indicativos de
conforto térmico para os animais alojados.Seria recomendado que os produtores
fossem mais cautelosos no manejo relacionado ao tempo em que os animais
permanecem na sala de espera da ordenha e que o revolvimento da cama do CB fosse
realizado durante o perĂodo em que as vacas tivessem sendo ordenhadas.</p
Milk fatty acid profile of Holstein x Gyr cows on 'Marandu' grass pasture under different grazing strategies
Characterisation of microbial attack on archaeological bone
As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved
7th drug hypersensitivity meeting: part one
Table of contents
Oral Abstracts
O1 Functionally distinct HMGB1 isoforms correlate with physiological processes in drug-induced SJS/TEN
Daniel F. Carr, Wen-Hung Chung, Rosalind E. Jenkiins, Mas Chaponda, Gospel Nwikue, Elena M. Cornejo Castro, Daniel J. Antoine, Munir Pirmohamed
O2 Hypersensitivity reactions to beta-lactams, does the t cell recognition pattern influence the clinical picture?
Natascha Wuillemin, Dolores Dina, Klara K. Eriksson, Daniel Yerly
O3 Specific binding characteristics of HLA alleles associated with nevirapine hypersensitivity
Rebecca Pavlos, Elizabeth Mckinnin, David Ostrov, Bjoern Peters, Soren Buus, David Koelle, Abha Chopra, Craig Rive, Alec Redwood, Susana Restrepo, Austin Bracey, Jing Yuan, Silvana Gaudieri, Mary Carrington, David Haas, Simon Mallal, Elizabeth Phillips
O4 Do we need to measure total ige for the interpretation of analytical results of ImmunoCAP dnd 3gAllergy specific IgE?
Douwe De Boer, Paul Menheere, Chris Nieuwhof, Judith Bons
O5 Neutrophil activation in systemic anaphylaxis: results from the multicentric NASA study
Friederike Jonsson, Luc De Chaisemartin, Vanessa Granger, Caitlin Gillis, Aurelie Gouel, Catherine Neukirch, Fadia Dib, Pascale Roland Nicaise, Dan Longrois, Florence Tubach, Sylvie Martin, Pierre Bruhns, NASA Study Group
O6 Purpuric drug eruptions due to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) for non-small-cell lung cancer (NSCLC): a clinic-pathological study of 32 cases
Kai-Lung Chen, Shu-Ling Liao, Yi-Shuan Sheen, Yung-Tsu Cho, Che-Wen Yang, Jau-Yu Liau, Chia-Yu Chu
Poster presentations: Poster Walk 1âAnaphylaxis (P01âP09)
P1 Anaphylactic reactions during anaesthesia and the perioperative period
Rita Aguiar, Anabela Lopes, NatĂĄlia Fernandes, Leonor Viegas, M. A. Pereira-Barbosa
P2 Anaphylaxis to chlorhexidine: is there a cross-reactivity to alexidine?
Antonia BĂŒnter, Nisha Gupta, Tatjana Pecaric Petkovic, Nicole Wirth, Werner J. Pichler, Oliver Hausmann
P3 Cefotaxime-induced severe anaphylaxis in a neonate
Mehtap Yazicioglu, Pinar G. Ozdemir, Gokce Ciplak, Ozkan Kaya
P4 Clinical features and diagnosis of anaphylaxis resulting from exposure to chlorhexidine
Peter John Cooke
P5 Drug-induced anaphylaxis: five-year single-center survey
InĂȘs Mota, Ăngela Gaspar, Filipe Benito-Garcia, Marta Chambel, MĂĄrio Morais-Almeida
P6 Intraoperative severe anaphylactic reaction due to patent blue v dye
Luis Marques, Eva Alcoceba, Silvia Lara
P7 Kounis syndrome in the setting of anaphylaxis to diclofenac
Leonor Carneiro-LeĂŁo, Carmen Botelho, Eunice Dias-Castro, Josefina Cernadas
P8 Perioperative anaphylaxis audit: Royal Melbourne Hospital
Katherine Nicholls, William Lay, Olivia Smith, Christine Collins, Gary Unglik, Kymble Spriggs, Priscilla Auyeung, Jeremy McComish, Jo A. Douglass
P9 Recurrent peri-operative anaphylaxis: a perfect storm
Jonny G. Peter, Paul Potter
Poster Walk 2: DH regions and patient groups (P10âP19)
P10 A rare presentation of amoxicillin allergy in a young child
FabrĂcia Carolino, Eunice Dias De Castro, Josefina R. Cernadas
P11 Adverse drug reactions in children: antibiotics or virus?
Ana Sofia Moreira, Carmo Abreu, Eva Gomes
P12 Allergic reactions in invasive medical procedures
BĂĄrbara Kong Cardoso, Elza Tomaz, Sara Correia, Filipe InĂĄcio
P13 Antibiotic allergy in children: room for improvement
Annabelle Arnold, Natasha Bear, Kristina Rueter, Grace Gong, Michael OâSullivan, Saravanan Muthusamy, Valerie Noble, Michaela Lucas
P14 Drug hypersensitivity reactions in children and results of diagnostic evaluation
Neringa Buterleviciute, Odilija Rudzeviciene
P15 Nonimmediate cutaneous drug reactions in children: are skin tests required?
Ana Sofia Moreira, Carmo Abreu, Eva Gomes
P16 Pediatric patients with a history of penicillin allergy and a positive penicillin skin test may not be at an increased risk for multiple drug allergies
Sara May, Thanai Pongdee, Miguel Park
P17 Proved hypersensitivity to drugs according data of Vilnius University Hospital Santariskiu Klinikos
Linas Griguola, Arturas Vinikovas, Simona KaĆĄinskaite, Violeta Kvedariene
P18 Self-reported prevalence of drug hypersensitivity reactions among students in Celal Bayar University, Turkey
Ayse Aktas, Suheyla Rahman, Huseyin Elbi, Beyhan Cengiz Ozyurt
P19 Severe drug hypersensitivity reactions in pediatric age
Ozlem Cavkaytar, Betul Karaatmaca, Pinar Gur Cetinkaya, Saliha Esenboga, Umit M. Sahiner, Bulent E. Sekerel, Ozge Soyer
Poster Walk 3: Desensitisation (P20âP28)
P20 A protocol for desensitisation to valaciclovir
Celia Zubrinich, Bianca Tong, Mittal Patel, Michelle Giles, Robyn OâHehir, Robert Puy
P21 A rare case of desensitization to modafinil
Josefina Cernadas, LuĂs Amaral, FabrĂcia Carolino
P22 A sixteen-day desensitization protocol in delayed type hypersensitivity reactions to oral drugs
Semra Demir, Asli Gelincik, Muge Olgac, Raif Caskun, Derya Unal, Bahauddin Colakoglu, Suna Buyukozturk
P23 Desensitization to intravenous etoposide using a 12 and a 13-step protocol. Two cases report
Olga Vega Matute, Amalia Bernad, Gabriel Gastaminza, Roselle Madamba, Carlos Lacasa, M. J. Goikoetxea, Carmen DâAmelio, Jose RifĂłn, Nicolas MartĂnez, Marta Ferrer
P24 Drug desensitisation in oncology: the experience of an immunoallergology department for 5Â years
Carmelita Ribeiro, EmĂlia Faria, Cristina Frutuoso, Anabela Barros, RosĂĄrio Lebre, Alice Pego, Ana Todo Bom
P25 Filgrastim anaphylaxis: a successful desensitization protocol
Luis Amaral, Josefina Cernadas
P26 Galsulfase hypersensitivity and desensitization of a mucopolysaccharidosis VI patient
Luis Felipe Ensina, Carolina Aranda, Ines Camelo Nunes, Ana Maria Martins, Dirceu Solé
P27 Rapid drug desensitization with biologicals: one-center experience with four biologicals
Sevim Bavbek, Resat Kendirlinan, Pamir Ăerçi, Seda Tutluer, Sadan Soyyigit, Zeynep Ăelebi Sözener, ĂmĂŒr Aydin, Reyhan GĂŒmĂŒsburun
P28 Successful desensitization to a high dose of methotrexate in a delayed type hypersensitivity reaction
Josefina Cernadas, Leonor Carneiro-LeĂŁo, FabrĂcia Carolino, Marta Almeida
Poster Walk 4: SJS (P29âP38)
P29 Assessment of impact of infection on drug-induced severe cutaneous adverse reactions and rhabdomyolysis using the Japanese adverse drug event report database
Kimie Sai, Takuya Imatoh, Ryosuke Nakamura, Chisato Fukazawa, Yasushi Hinomura, Yoshiro Saito
P30 Characterization of erythema multiforme and severe cutaneous adverse reactions hospitalizations
Bernardo Sousa-Pinto, ClĂĄudia Correia, LĂdia Gomes, Sara Gil-Mata, LuĂs AraĂșjo, LuĂs Delgado
P31 Effects of infection on incidence/severity of SJS/TEN and myopathy in Japanese cases analyzed by voluntary case reports
Ryosuke Nakamura, Kimie Sai, Takuya Imatoh, Yoshimi Okamoto-Uchida, Koji Kajinami, Kayoko Matsunaga, Michiko Aihara, Yoshiro Saito
P32 Efficacy of tumor necrosis factorâa antagonists in StevensâJohnson syndrome and toxic epidermal necrolysis: a randomized controlled trial and immunosuppressive effects evaluation
Chuang-Wei Wang, Shih-Chi Su, Shuen-Iu Hung, Hsin-Chun Ho, Chih-Hsun Yang, Wen-Hung Chung
P33 Evolution of drug causality in StevensâJohnson syndrome and toxic epidermal necrolysis in Europe: analysis of 10Â years RegiSCAR-Study
Maren Paulmann, Ariane Dunant, Maja Mockenhaupt, Peggy Sekula, Martin Schumacher, Sylvia Kardaun, Luigi Naldi, Teresa Bellón, Daniel Creamer, Cynthia Haddad, Bruno Sassolas, Bénédicte Lebrun-Vignes, Laurence Valeyrie-Allanore, Jean-Claude Roujeau
P34 Long-term sequelae in patients with StevensâJohnson syndrome and toxic epidermal necrolysis: a 5-year analysis
Maren Paulmann, Carmen Kremmler, Peggy Sekula, Laurence Valeyrie-Allanore, Luigi Naldi, Sylvia Kardaun, Maja Mockenhaupt
P35 Major emotional complications and decreased health related quality of life among survivors of StevensâJohnson syndrome and toxic epidermal necrolysis
Roni P. Dodiuk-Gad, Cristina Olteanu, Anthony Feinstein, Rena Hashimoto, Raed Alhusayen, Sonia Whyte-Croasdaile, Yaron Finkelstein, Marjorie Burnett, Shachar Sade, Robert Cartotto, Marc Jeschke, Neil H. Shear
P36 Retrospective analysis of StevensâJohnson syndrome and toxic epidermal necrolysis in Japanese patients: treatment and outcome
Naoko Takamura, Yumiko Yamane, Setsuko Matsukura, Kazuko Nakamura, Yuko Watanabe, Yukie Yamaguchi, Takeshi Kambara, Zenro Ikezawa, Michiko Aihara
P37 Severe physical complications among survivors of StevensâJohnson syndrome and toxic epidermal necrolysis
Roni P. Dodiuk-Gad, Cristina Olteanu, Rena Hashimoto, Hall Chew, Raed Alhusayen, Sonia Whyte-Croasdaile, Yaron Finkelstein, Marjorie Burnett, Shachar Sade, Robert Cartotto, Marc Jeschke, Neil H. Shear
P38 StevensâJohnson syndrome/toxic epidermal necrolysis combined with haemophagocytic lymphohistiocytosis: a case report
Brittany Knezevic, Una Nic Ionmhain, Allison Barraclough, Michaela Lucas, Matthew Anstey
Poster Walk 5: Other organs/unexpected immune reactions (P39âP47)
P39 A case report of patient with anti-tuberculosis drug-related severe liver failure
Toru Usui, Xiaoli Meng, John Farrell, Paul Whitaker, John Watson, Neil French, Kevin Park, Dean Naisbitt
P40 Acute interstitial nephritis induced by ibuprofen
Ana Castro Neves, Susana Cadinha, Ana Moreira, J. P. Moreira Da Silva
P41 Cetuximab induced acneiform rashâtwo case reports
Daniela Ledic Drvar, Sandra Jerkovic Gulin, Suzana Ljubojevic Hadzavdic, Romana Ceovic
P42 Enteropathy associated with losartan
Ana Montoro De Francisco, TalĂa De Vicente JimĂ©nez, Amelia GarcĂa Luque, Natalia Rosado David, JosĂ© MÂȘ Mateos GalvĂĄn
P43 Granuloma annulare after therapy with canakinumab
Razvigor Darlenski
P44 Hypersensitivity eosinophilic myocarditis or acute coronary syndrome? Case report
Dario Gulin, Jozica Sikic, Jasna Cerkez Habek, Sandra Jerkovic Gulin, Edvard Galic
P45 Piperacillin-induced immune haemolytic anaemia: a severe and frequent complication of antibiotic treatment in patients with cystic fibrosis
Philip Specht, Doris Staab, Beate Mayer, Jobst Roehmel
P46 Progesterone triggered pemphigus foliaceus: case report
Sandra Jerkovic Gulin, Caius Solovan, Anca Chiriac
P47 Ramipril: triggered generalized pustular psoriasis
Paola Djurinec, Kresimir Kostovic, Mirna Bradamante, Sandra Jerkovic Gulin, Romana Ceovic
Poster Walk 6: NSAIDs (P48âP56)
P48 Aspirin desensitization in cardiovascular diseaseâPortuguese experience
Jose Pedro Almeida, Joana Caiado, Elisa Pedro, Pedro Canas Da Silva, Manuel Pereira Barbosa
P49 Asthma and/or rhinitis to NSAIDs with good tolerance to ASA
Gador Bogas, Natalia Blanca-LĂłpez, Diana PĂ©rez-Alzate, Inmaculada Doña, JosĂ© Augusto AgĂșndez, Elena GarcĂa-MartĂn, JosĂ© Antonio Cornejo-GarcĂa, Cristobalina Mayorga, MarĂa JosĂ© Torres, Gabriela Canto, Miguel Blanca
P50 Clinical characteristics of 196 patients with non-steroidal anti-inflammatory drug (NSAIDs) hypersensitivity
SengĂŒl Aksakal, AytĂŒl Zerrin Sin, Zeynep Peker Koç, Fatma DĂŒsĂŒnĂŒr GĂŒnsen, ĂmĂŒr Ardeniz, Emine Nihal Mete Gökmen, Okan GĂŒlbahar, Ali Kokuludag
P51 Development of immediate hypersensitivity to several NSAIDs maintaining good tolerance to ASA
Natalia PĂ©rez-SĂĄnchez, Natalia Blanca-LĂłpez, Diana PĂ©rez-Alzate, Gador Bogas, Inmaculada Doña, MarĂa Salas, MarĂa JosĂ© Torres, Miguel Blanca, Gabriela Canto
P52 Diagnosis of hypersensitivity reactions to paracetamol in a large series of cases
Inmaculada Doña, Maria Salas, Francisca Gomez, Natalia Blanca-Lopez, Diana Perez-Alzate, Gador Bogas, Esther Barrionuevo, Maria Jose Torres, Inmaculada Andreu, Miguel Ăngel Miranda, Gabriela Canto, Miguel Blanca
P53 Hypersensitivity to paracetamol according to the new classification of hypersensitivity to NSAIDs
Gabija DidĆŸiokaite, Olesia Gaidej, Simona KaĆĄinskaite, Violeta Kvedariene
P54 Ibuprofen and other aryl propionic derivates can induce immediate selective hypersensitivity responses
Diana Perez-Alzate, Natalia Blanca-López, Maria Isabel Garcimartin, Inmaculada Doña, Maria Luisa Somoza, Cristobalina Mayorga, Maria Jose Torres, Gador Bojas, Jose Antonio Cornejo-Garcia, Maria Gabriela Canto, Miguel Blanca
P55 Subjects developing immediate responses to several NSAIDs can be selective with good tolerance to ASA
Natalia Blanca-Lopez, Diana Pérez-Alzate, Francisco Javier Ruano Perez, Inmaculada Doña, Maria Luisa Somoza, Inmaculada Andreu, Miguel Angel Miranda, Cristobalina Mayorga, Maria Jose Torres, Jose Antonio Cornejo-Garcia, Miguel Blanca, Maria Gabriela Canto
P56 Utility of low-dose oral aspirin challenges for diagnosis of aspirin exacerbated respiratory disease
Elina Jerschow, Teresa Pelletier, Zhen Ren, Golda Hudes, Marek Sanak, Esperanza Morales, Victor Schuster, Simon D. Spivack, David Rosenstreich
Poster Walk 7: NSAID 2 (P57âP65)
P57 Alternate regulation of cyclooxygenase-2 (COX-2) MRNA expression may predispose patients to aspirin-induced exacerbations
Renato Erzen, Mira Silar, Nissera Bajrovic, Matija Rijavec, Mihaela Zidarn, Peter Korosec
P58 Anaphylaxis to diclofenac: what about the underlying mechanism?
Leonor Carneiro-LeĂŁo, FabrĂcia Carolino, LuĂs Amaral, Carmen Botelho, Eunice Dias-Castro, Josefina Cernadas
P59 COX-2 inhibitors: are they always a safe alternative in hypersensitivity to nonsteroidal anti-inflammatory drugs?
Luis Amaral, Fabricia Carolino, Eunice Castro, Josefina Cernadas
P60 Management of patients with history of NSAIDs reactions prior to coronary angioplasty
Mona Al-Ahmad, Tito Rodriguez
P61 Oral drug challenge with non-steroidal anti-inflammatory drug under spirometric control: clinical series of 110 patients
JoĂŁo Pedro Azevedo, EmĂlia Faria, Beatriz Tavares, Frederico Regateiro, Ana Todo-Bom
P62 Prevalence and incidence of analgesic hypersensitivity reactions in Colombia
Pablo Andrés Miranda, Bautista De La Cruz Hoyos
P63 Recent endoscopic sinus surgery lessens reactions during aspirin challenge in patients with aspirin exacerbated respiratory disease
Teresa Pelletier, Waleed Abuzeid, Nadeem Akbar, Marc Gibber, Marvin Fried, Weiguo Han, Taha Keskin, Robert Tamayev, Golda Hudes, Simon D. Spivack, David Rosenstreich, Elina Jerschow
P64 Safe use of imidazole salycilate in a case of multiple NSAIDs induced urticaria-angioedema
Elisa Boni, Marina Russello, Marina Mauro
P65 Selective hypersensitivity reactions to ibuprofenâseven years experience
Marta Ferreira Neto
Poster Walk 8: Epidemiological methods (P66âP72)
P66 Allopurinol hypersensitivity: a 7-year review
Lise Brosseron, Daniela Malheiro, Susana Cadinha, PatrĂcia Barreira, J. P. Moreira Da Silva
P67 Antibiotic allergy labelling is associated with increased hospital readmission rates in Australia
Brittany Knezevic, Dustin Sprigg, Michelle Trevenen, Jason Seet, Jason Trubiano, William Smith, Yogesh Jeelall, Sandra Vale, Richard Loh, Andrew Mclean-Tooke, Michaela Lucas
P68 Expertsâ opinions on severe cutaneous adverse drug reactions-report of a survey from the 9th international congress on cutaneous adverse drug reactions 2015
Roni P. Dodiuk-Gad, Cristina Olteanu, Wen-Hung Chung, Neil H. Shear
P69 HLA-A*31-positive AGEP with carbamazepine use and other severe cutaneous adverse drug reactions (SCARs) detected by electronic medical records screening
Sabine MĂŒller, Ursula Amstutz, Lukas Jörg, Nikhil Yawalkar, Stephan KrĂ€henbĂŒhl
P70 Patients with suspected drug allergy: a specific psychological profile?
Eunice Dias-Castro, Ana Leblanc, Laura Ribeiro, Josefina R. Cernadas
P71 Use of an electronic device and a computerized mathematic algorithm to detect the allergic drug reactions through the analysis of heart rate variability
Arantza Vega, Raquel Gutierrez Rivas, Ana Alonso, Juan Maria Beitia, Belén Mateo, Remedios Cårdenas, Juan Jesus Garcia-Dominguez
P72 Variation in ERAP influences risk for HLA-B*57:01 positive abacavir hypersensitivity
Rebecca Pavlos, Kaija Strautins, Ian James, Simon Mallal, Alec Redwood, Elizabeth Phillips
Poster Walk 9: DRESS/AGEP (P73âP81)
P73 A clinical case of DRESS syndrome in a child after administration of amoxicillin-clavulanic acid
Rita Aguiar, Anabela Lopes, Ana Neves, Maria Do CĂ©u Machado, M. A. Pereira-Barbosa
P74 Acute generalized exanthematous pustulosis (AGEP) induced by mesalazine, reliable and oftenly used drug to treat inflammatory bowel disease
Ceyda Tunakan Dalgiç, Emine Nihal Mete Gökmen, Fatma DĂŒsĂŒnĂŒr GĂŒnsen, Gökten Bulut, Fatma ĂmĂŒr Ardeniz, Okan GĂŒlbahar, Ali Kokuludag, AytĂŒl Zerrin Sin
P75 Changes of blood plasmacytoid dendritic cells, myeloid dendritic cells, and basophils during the acute stage of drug reaction with eosinophilia and systemic symptoms (DRESS) and other drug eruptions
Shao-Hsuan Hsu, Yung-Tsu Cho, Che-Wen Yang, Kai-Lung Chen, Chia-Yu Chu
P76 Characterization of isoniazid/rifampicin-specific t-cell responses in patients with DRESS syndrome
Young-Min Ye, Gyu-Young Hur, Hae-Sim Park, Seung-Hyun Kim
P77 DRESS syndrome secondary to sulfasalazine with delayed TEN: a case presentation
Syed Ali, Michaela Lucas, Peter N. Hollingsworth, Andrew P. C. Mclean-Tooke
P78 Drug rash with eosinophilia and systemic symptoms (DRESS) features according to the culprit drug
Zohra Chadly, Nadia Ben Fredj, Karim Aouam, Haifa Ben Romdhane, Naceur A. Boughattas, Amel Chaabane
P79 Drug reaction with eosinophilia and systemic symptoms induced by allopurinol: not always easy to diagnose
Marina Lluncor Salazar, Beatriz Pola, Ana Fiandor, Teresa BellĂłn, Elena RamĂrez, Javier DomĂnguez Ortega, Santiago Quirce, Rosario Cabañas
P80 Drug reaction with eosinophilia and systemic symptoms syndrome induced by two drugs simultaneously: a case report
Krasimira Baynova, Marina Labella, Manuel Prados
P81 The drug reaction with eosinophilia and systemic symptoms (DRESS) induced by the second-line antituberculosis drugs and EpsteinâBarr virus infection
Agne Ramonaite, Ieva Bajoriuniene, Brigita Sitkauskiene, Raimundas Sakalauskas
Poster Walk 10: Miscellaneous drug hypersensitivity (P82âP91)
P82 A case of cycloserine-induced lichenoid drug eruption confirmed with a lymphocatye transformation test
Jae-Woo Kwon, Shinyoung Park
P83 Allergic reaction to topical eye drops: 5Â yearsâ retrospective study in a drug allergy unit
Diana Silva, Leonor Carneiro LeĂŁo, Fabricia Carolino, Eunice Castro, Josefina Cernadas
P84 Allergy to heparins
Diana Perez-Alzate, Natalia Blanca-LĂłpez, Maria Luisa Somoza Alvarez, Maria Garcimartin, Maria Vazquez De La Torre, Francisco Javier Ruano PĂ©rez, Elisa Haroun, Gabriela Canto Diez
P85 Allopurinol-induced adverse drug reactions
Katinka Ănodi-Nagy, Ăgnes KinyĂł, Lajos KemĂ©ny, Zsuzsanna Bata-Csörgo
P86 Analysis of a population with immediate hypersensitivity to corticosteroids: an 11Â year review
Joana Sofia Pita, EmĂlia Faria, Rosa Anita Fernandes, Ana Moura, Nuno Sousa, Carmelita Ribeiro, Carlos Loureiro, Ana Todo Bom
P87 Anaphylaxis against mivacurium in a 12-months old boy at first-time exposure
Wolfgang PfĂŒtzner
P88 Antihistamine-exacerbated chronic spontaneous urticaria: a paradox?
Nadine Marrouche, Clive Grattan
P89 Anti-osteoporotic agents-induced cutaneous adverse drug reactions in Asians
Yu-En Chen, Chun-Bing Chen, Wen-Hung Chung, Yu-