51 research outputs found

    Características asociadas al comportamiento del consumidor en la empresa Riko´s Chicken en la ciudad de Chepén, 2022

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    La presente investigación buscó determinar las características asociadas al comportamiento del consumidor de la empresa Riko’s Chicken en la ciudad de Chepén en el 2022. Con respecto a la metodología de la investigación, se pudo determinar que fue aplicada, con un diseño cuantitativo de tipo no experimental y de nivel correlacional multivariado. La población objeto de estudio fue infinita y estuvo conformada por los clientes de la empresa Riko´s Chicken en la ciudad de Chepén en el año 2022, siendo la muestra de 168 clientes. Así mismo, se empleó el muestreo probabilístico, en la modalidad de aleatorio simple; además, el instrumento aplicado fue el cuestionario para evaluar a cada una de las variables, usando una escala de tipo Likert. También, se llevó a cabo el alfa de Cronbach dando como resultado el valor de 0.96, indicando que el cuestionario tiene un muy elevado nivel de confiabilidad. Como resultados se obtuvo que la regresión logística ha logrado un 78.0% de pronóstico, asimismo se identificó algunas características que pueden influir en el comportamiento del consumidor

    Shining Light on Merging Galaxies I: The Ongoing Merger of a Quasar with a `Green Valley' Galaxy

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    Serendipitous observations of a pair z = 0.37 interacting galaxies (one hosting a quasar) show a massive gaseous bridge of material connecting the two objects. This bridge is photoionized by the quasar (QSO) revealing gas along the entire projected 38 kpc sightline connecting the two galaxies. The emission lines that result give an unprecedented opportunity to study the merger process at this redshift. We determine the kinematics, ionization parameter (log U ~ -2.5 +- 0.03), column density (N_H ~ 10^{21} cm^{-2}), metallicity ([M/H] ~ -0.20 +- 0.15), and mass (~ 10^8 Msun) of the gaseous bridge. We simultaneously constrain properties of the QSO-host (M_DM>8.8x 10^{11} Msun) and its companion galaxy (M_DM>2.1 x 10^{11} Msun; M_star ~ 2 x 10^{10} Msun; stellar burst age=300-800 Myr; SFR~6 Msun/yr; and metallicity 12+log (O/H)= 8.64 +- 0.2). The general properties of this system match the standard paradigm of a galaxy-galaxy merger caught between first and second passage while one of the galaxies hosts an active quasar. The companion galaxy lies in the so-called `green valley', with a stellar population consistent with a recent starburst triggered during the first passage of the merger and has no detectable AGN activity. In addition to providing case-studies of quasars associated with galaxy mergers, quasar/galaxy pairs with QSO-photoionized tidal bridges such as this one offer unique insights into the galaxy properties while also distinguishing an important and inadequately understood phase of galaxy evolution.Comment: 23 pages, 12 figures, 5 tables, Submitted to ApJ, revised to address referee's comment

    Proyecto Psicosalud

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    En el siguiente trabajo se presenta el plan de negocio de un aplicativo móvil que permitirá realizar consultas psicológicas con especialistas de manera virtual, dirigido a adultos de 18 a 39 años de edad que sufran de ansiedad, estrés y depresión, PsicoSalud. En los primeros capítulos validamos la problemática planteada mediante experimentos como entrevistas a usuarios y expertos. En el siguiente capítulo se desarrolló la descripción del perfil del cliente, mapa de valor, encaje, descripción de la propuesta de valor e identificación de los elementos diferenciales del proyecto. Con ello, se realizó el Business Model Canvas del proyecto. En los siguientes 2 capítulos se validó la solución mediante 3 experimentos: como entrevista a usuarios, formularios y finalmente focus group. Como validación del negocio se realizaron diversos experimentos, entre ellos, revisión de fuentes secundarias, creación de las redes sociales donde evaluamos el interés de los usuarios, se realizó una oferta laboral a psicólogos y entrevista a desarrolladores de softwares. El siguiente capítulo, el plan de Ejecución del Concierge, se realizaron 4 experimentos en redes sociales como landing page y anuncio pagado, promociones de planes de servicio (mensual, trimestral y semestral) y se contactó como influencer a una marca enfocada en vida saludable con el objetivo de definir el interés de compra. Como parte del siguiente capítulo se realizó el plan de marketing detallando los objetivos y estableciendo estrategias de las 4Ps. Finalmente se procedió a realizar el plan financiero el cual resultó en viabilidad y una rentabilidad favorable para el proyecto.The following work presents the business plan of a mobile application, Psicosalud, that will allow psychological consultations with specialists virtually, aimed at adults between 18 and 39 years of age who suffer from anxiety, stress and depression. In the first chapters we validate the problem through experiments such as interviews with users and experts. In the next chapter, the description of the client's profile, value map, fit, description of the value proposition and identification of the project's differential elements. With this, the Business Model Canvas of the project was made. In the following 2 chapters the solution is validated through 3 experiments: an interview with users, forms and finally a focus group. As a validation of the business, various experiments were carried out, among them, a review of secondary sources, the creation of social networks where we evaluated the interest of users, a job offer was made for psychologists and an interview with software developers. The next chapter, the Concierge Execution plan, 4 experiments were carried out in social networks such as landing page and paid advertisement, service plan promotions (monthly, quarterly and semester) and a brand focused on healthy living was contacted as an influencer with the objective of defining the buying interest. As part of the next chapter, the marketing plan was carried out: Results, objectives and establishing strategies of the 4P’s. Finally, the financial plan was carried out, which resulted in viability and a favorable profitability for the project.Trabajo de investigació

    Tipos de familia e ideación suicida en estudiantes de secundaria de una institución educativa de Tacna-Perú, 2019

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    The general objective of the research was to establish the relationship between family types and suicidal ideation in students of secondary school in an educational institution in Tacna-Peru. It consisted of a quantitative, cross-sectional, descriptive correlational study. The method used was the survey and the instruments applied were: Olson's Family Cohesion and Adaptability Scale and Beck's Suicidal Ideation Scale. The sample consisted of 378 adolescents between 14 and 17 years of age. The results indicated that there is no relationship between family types and suicidal ideation in students of secondary school in an educational institution in Tacna (bilateral sig. = 0.874); likewise, the chaotically separated family type is the most frequent (21.2%); finally, the students present a slight level of risk of suicidal ideation (70.9%). The conclusion is that family type is not a factor that determines the levels of suicidal ideation.El objetivo general de la investigación fue establecer la relación entre los tipos de familia y la ideación suicida en estudiantes de secundaria de una institución educativa de Tacna-Perú. Consistió en un estudio cuantitativo, transversal y descriptivo correlacional. El método utilizado fue la encuesta y los instrumentos aplicados fueron: Escala de Cohesión y Adaptabilidad Familiar de Olson y Escala de Ideación Suicida de Beck. La muestra fue de 378 adolescentes de 14 a 17 años. Los resultados indicaron que no existe relación entre los tipos de familia y la ideación suicida en los estudiantes de secundaria de una institución educativa de Tacna (sig. bilateral = 0,874); asimismo, el tipo de familia separada caóticamente es el más frecuente (21,2%); finalmente, los estudiantes presentan un nivel leve de riesgo de ideación suicida (70,9%). La conclusión es que el tipo de familia no es un factor que determine los niveles de ideación suicida

    ACE Score Identifies HBeAg-negative Inactive Carriers at a Single-point Evaluation, Regardless of HBV Genotype

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    HBV DNA; Hepatitis B virus; Inactive carrierADN del VHB; Virus de la hepatitis B; Portador inactivoADN del VHB; Virus de l'hepatitis B; Portador inactiuBackground and Aims Hepatitis B virus (HBV) biomarkers have been used for a better categorization of patients, even though the lack of simple algorithms and the impact of genotypes limit their application. Our aim was to assess the usefulness of noninvasive markers for the identification of HBV inactive carriers (ICs) in a single-point evaluation and to design a predictive model for their identification. Methods This retrospective-prospective study included 343 consecutive HBeAg-negative individuals. Clinical, analytical, and virological data were collected, and a liver biopsy was performed if needed. Subjects were classified at the end of follow-up as ICs, chronic hepatitis B and gray zone.A predictive model was constructed, and validated by 1000-bootstrap samples. Results After 39 months of follow-up, 298 subjects were ICs, 36 were chronic hepatitis B CHB, and nine were gray zone. Eighty-nine (25.9%) individuals required a liver biopsy. Baseline HBV DNA hazard ratio (HR) 6.0, p<0.001), HBV core-related antigen (HBcrAg) (HR 6.5, p<0.001), and elastography (HR 4.6, p<0.001) were independently associated with the IC stage. The ACE score (HBV DNA, HBcrAg, elastography), obtained by bootstrapping, yielded an area under the receiver operating characteristics (AUROC) of 0.925 (95% CI: 0.880–0.970, p<0.001) for identification of ICs. The AUROC for genotype D was 0.95, 0.96 for A, 0.90 for E, and 0.88 for H/F. An ACE score of <1 had a positive predictive value of 99.5%, and a score ≤12 points had a diagnostic accuracy of 93.8%. Conclusions Low baseline HBV DNA, HBcrAg, and liver stiffness were independently associated with the IC phase. A score including those variables identified ICs at a single-point evaluation, and might be applied to implement less intensive follow-up strategies.This study received partial financial support from Instituto de Salud Carlos III (PI17/02233 and PI20/01692)

    A multi-site campaign to measure solar-like oscillations in Procyon. II. Mode frequencies

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    We have analyzed data from a multi-site campaign to observe oscillations in the F5 star Procyon. The data consist of high-precision velocities that we obtained over more than three weeks with eleven telescopes. A new method for adjusting the data weights allows us to suppress the sidelobes in the power spectrum. Stacking the power spectrum in a so-called echelle diagram reveals two clear ridges that we identify with even and odd values of the angular degree (l=0 and 2, and l=1 and 3, respectively). We interpret a strong, narrow peak at 446 muHz that lies close to the l=1 ridge as a mode with mixed character. We show that the frequencies of the ridge centroids and their separations are useful diagnostics for asteroseismology. In particular, variations in the large separation appear to indicate a glitch in the sound-speed profile at an acoustic depth of about 1000 s. We list frequencies for 55 modes extracted from the data spanning 20 radial orders, a range comparable to the best solar data, which will provide valuable constraints for theoretical models. A preliminary comparison with published models shows that the offset between observed and calculated frequencies for the radial modes is very different for Procyon than for the Sun and other cool stars. We find the mean lifetime of the modes in Procyon to be 1.29 +0.55/-0.49 days, which is significantly shorter than the 2-4 days seen in the Sun.Comment: accepted for publication in Ap

    High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods

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    HepatitisCvirus(HCV)is classified into seven major genotypesand67 subtypes. Recent studies haveshownthat inHCVgenotype 1-infected patients, response rates to regimens containingdirect-acting antivirals(DAAs)are subtype dependent. Currently available genotypingmethods have limited subtyping accuracy.Wehave evaluated theperformanceof adeep-sequencing-basedHCVsubtyping assay, developed for the 454/GS-Junior platform, in comparisonwith thoseof two commercial assays (VersantHCVgenotype 2.0andAbbott Real-timeHCVGenotype II)andusingdirectNS5Bsequencing as a gold standard (direct sequencing), in 114 clinical specimenspreviously tested by first-generation hybridization assay (82 genotype 1and32 with uninterpretable results). Phylogenetic analysis of deep-sequencing reads matched subtype 1 callingbypopulation Sanger sequencing(69%1b,31%1a) in 81 specimensandidentified amixed-subtype infection (1b/3a/1a) in one sample. Similarly,amongthe 32previously indeterminate specimens, identical genotypeandsubtype results were obtained by directanddeep sequencing in all but four samples with dual infection. In contrast, both VersantHCVGenotype 2.0andAbbott Real-timeHCVGenotype II failed subtype 1 calling in 13 (16%) samples eachandwere unable to identify theHCVgenotype and/or subtype inmore than half of the nongenotype 1 samples.Weconcluded that deep sequencing ismore efficient forHCVsubtyping than currently available methodsandallows qualitative identificationofmixed infectionsandmay bemorehelpfulwith respect to informing treatment strategies withnewDAA-containing regimens across allHCVsubtypesThis study has been supported by CDTI (Centro para el Desarrollo Tecnológico Industrial), Spanish Ministry of Economics and Competitiveness (MINECO), IDI-20110115; MINECO projects SAF 2009-10403; and also by the Spanish Ministry of Health, Instituto de Salud Carlos III (FIS) projects PI10/01505, PI12/01893, and PI13/00456. CIBERehd is funded by the Instituto de Salud Carlos III, Madrid, Spain. Work at CBMSO was supported by grant MINECO-BFU2011-23604, FIPSE, and Fundación Ramón Areces. X. Forns received unrestricted grant support from Roche and has acted as advisor for MSD, Gilead, and Abbvie. M. Alvarez-Tejado, J. Gregori, and J. M. Muñoz work in Roche Diagnostic

    An Insertion Within SIRPß1 Shows a Dual Effect Over Alzheimer's Disease Cognitive Decline Altering the Microglial Response

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