Disappearance of quasi-periodic-eruptions (QPEs) in GSN 069, simultaneous X-ray re-brightening, and predicted QPE re-appearance

We study the short- and long-timescale properties of quasi-periodic eruptions (QPEs) in GSN 069 and its overall X-ray evolution over the past 11 yr using 11 XMM-Newton and 1 Chandra observations from December 2010 to December 2021. QPEs are a transient phenomenon in GSN 069 last detected in January 2020 with a life-time between 1 and 5.5 yr. On short timescales, the QPE intensity and recurrence time oscillate defining alternating strong/weak QPEs and long/short recurrence times. The quiescent level variability in observations with QPEs exhibits a quasi-periodic oscillation (QPO) at the average observation-dependent recurrence time peaking with a delay of a few hr w.r.t. the preceding QPE. A significant late-time X-ray re-brightening starting with the QPE disappearance is observed in the long-term light curve of the quiescent emission, and the overall X-ray evolution follows the relation expected from constant-area blackbody emission. QPEs in GSN 069 are consistent with being produced by repeating tidal stripping events of a white dwarf (WD) donor in a highly eccentric orbit around the supermassive black hole, one QPE being produced at each pericenter passage. Our data suggest that the WD was partially disrupted when QPEs disappeared in GSN 069, giving rise to the observed X-ray re-brightening. We predict the re-appearance of QPEs in GSN 0699 in the near future with different recurrence times than currently detected QPEs, as the surviving core will again suffer a series of tidal stripping events at pericenter passage.Comment: Submitted to A&A. Comments welcom

XMMSL2 J144605.0+685735: a slow tidal disruption event

Aims. We investigate the evolution of X-ray selected tidal disruption events. Methods. New events are found in near real-time data from XMM-Newton slews, and are monitored by multi-wavelength facilities. Results. In August 2016, X-ray emission was detected from the galaxy XMMSL2 J144605.0+685735 (also known as 2MASX 14460522+6857311), that was 20 times higher than an upper limit from 25 years earlier. The X-ray flux was flat for ∼100 days and then fell by a factor of 100 over the following 500 days. The UV flux was stable for the first 400 days before fading by a magnitude, while the optical (U,B,V) bands were roughly constant for 850 days. Optically, the galaxy appears to be quiescent, at a distance of 127 ± 4 Mpc (z = 0.029 ± 0.001) with a spectrum consisting of a young stellar population of 1–5 Gyr in age, an older population, and a total stellar mass of ∼6 × 109 M⊙. The bolometric luminosity peaked at Lbol ∼ 1043 ergs s−1 with an X-ray spectrum that may be modelled by a power law of Γ ∼ 2.6 or Comptonisation of a low-temperature thermal component by thermal electrons. We consider a tidal disruption event to be the most likely cause of the flare. Radio emission was absent in this event down to < 10 μJy, which limits the total energy of a hypothetical off-axis jet to E <  5 × 1050 ergs. The independent behaviour of the optical, UV, and X-ray light curves challenges models where the UV emission is produced by reprocessing of thermal nuclear emission or by stream-stream collisions. We suggest that the observed UV emission may have been produced from a truncated accretion disc and the X-rays from Compton upscattering of these disc photons

β3-adrenoceptor stimulation of perivascular adipocytes leads to increased fat cell-derived nitric oxide and vascular relaxation in small arteries

BACKGROUND AND PURPOSE In response to norepinephrine healthy perivascular adipose tissue (PVAT) exerts an anticontractile effect on adjacent small arterial tissue. Organ bath solution transfer experiments have demonstrated the release of PVAT-derived relaxing factors that mediate this function. The present studies were designed to investigate the mechanism responsible for the norepinephrine-induced PVAT anticontractile effect. EXPERIMENTAL APPROACH In vitro rat small arterial contractile function was assessed using wire myography in the presence and absence of PVAT and the effects of sympathomimetic stimulation on the PVAT environment explored using Western blotting and assays of organ bath buffer. KEY RESULTS PVAT elicited an anticontractile effect in response to norepinephrine but not phenylephrine stimulation. In arteries surrounded by intact PVAT, the β3-adrenoceptor agonist, CL-316,243 reduced the vasoconstrictor effect of phenylephrine but not norepinephrine. Kv7 channel inhibition using XE 991 reversed the norepinephrine-induced anticontractile effect in exogenously applied PVAT studies. Adrenergic stimulation of PVAT with norepinephrine and CL-316,243, but not phenylephrine was associated with increased adipocyte-derived nitric oxide production and the contractile response to norepinephrine was augmented following incubation of exogenous PVAT with L-NMMA. PVAT from eNOS-/- mice had no anticontractile effect. Assays of adipocyte cAMP demonstrated an increase with norepinephrine stimulation implicating Gαs signalling in this process. CONCLUSIONS AND IMPLICATIONS We have shown that adipocyte-located β3-adrenoceptor stimulation leads to activation of Gαs signaling pathways with increased cAMP and the release of adipocyte-derived nitric oxide. This process is dependent upon Kv7 channel function. We conclude that adipocyte-derived nitric oxide plays a central role in anticontractile activity when rodent PVAT is stimulated by norepinephrine

Simulations of multiphase turbulence in jet cocoons

M. Krause and P. Alexander, 'Simulations of multiphase turbulence in jet cocoons', Monthly Notices of the Royal Astronomical Society, Vol. 376, pp. 465-478, April 2007, the version of record is available online at doi: 10.1111/j.1365-2966.2007.11480.x. Published by Oxford University Press on behalf of the Royal Astronomical Society. © 2007 The Authors. Journal compilation © 2007 RASThe interaction of optically emitting clouds with warm X-ray gas and hot, tenuous radio plasma in radio jet cocoons is modelled by 2D compressible hydrodynamic simulations. The initial setup is the Kelvin–Helmholtz instability at a contact surface of density contrast 104. The denser medium contains clouds of higher density. Optically thin radiation is realized via a cooling source term. The cool phase effectively extracts energy from the other gas which is both, radiated away and used for acceleration of the cold phase. This increases the system’s cooling rate substantially and leads to a massively amplified cold mass dropout. We show that it is feasible, given small seed clouds of the order of 100 M, that all of the optically emitting gas in a radio jet cocoon may be produced by this mechanism on the propagation time-scale of the jet. The mass is generally distributed as T−1/2 with temperature, with a prominent peak at 14 000 K. This peak is likely to be related to the counteracting effects of shock heating and a strong rise in the cooling function. The volume filling factor of cold gas in this peak is of the order of 10−5–10−3 and generally increases during the simulation time. The simulations tend towards an isotropic scale-free Kolmogorov-type energy spectrum over the simulation time-scale. We find the same Mach-number density relation as Kritsuk & Norman and show that this relation may explain the velocity widths of emission lines associated with high-redshift radio galaxies, if the environmental temperature is lower, or the jet-ambient density ratio is less extreme than in their low-redshift counterparts.Peer reviewe

De-ubiquitination of ELK-1 by USP17 potentiates mitogenic gene expression and cell proliferation

ELK-1 is a transcription factor involved in ERK-induced cellular proliferation. Here we show that its transcriptional activity is modulated by ubiquitination at lysine 35 (K35). The level of ubiquitinated ELK-1 rises in mitogen-deprived cells and falls upon mitogen stimulation or oncogene expression. Ectopic expression of USP17, a cell cycle-dependent deubiquitinase, decreases ELK-1 ubiquitination and up-regulates ELK-1 target-genes with a concomitant increase in cyclin D1 expression. In contrast, USP17 depletion attenuates ELK-1-dependent gene expression and slows cell proliferation. The reduced rate of proliferation upon USP17 depletion appears to be a direct effect of ELK-1 ubiquitination because it is rescued by an ELK-1(K35R) mutant refractory to ubiquitination. Overall, our results show that ubiquitination of ELK-1 at K35, and its reversal by USP17, are important mechanisms in the regulation of nuclear ERK signalling and cellular proliferation. Our findings will be relevant for tumours that exhibit elevated USP17 expression and suggest a new target for intervention

Gully cut- and- fill cycles as related to agromanagement : a historical curve number simulation in the Tigray Highlands

Gully cut-and-fill dynamics are often thought to be driven by climate and/or deforestation related to population pressure. However, in this case-study of nine representative catchments in the Northern Ethiopian Highlands, we find that neither climate changes nor deforestation can explain gully morphology changes over the twentieth century. Firstly, by using a Monte Carlo simulation to estimate historical catchment-wide curve numbers, we show that the landscape was already heavily degraded in the nineteenth and early twentieth century – a period with low population density. The mean catchment-wide curve number (> 80) one century ago was, under the regional climatic conditions, already resulting in considerable simulated historical runoff responses. Secondly, twentieth century land-cover and runoff coefficient changes were confronted with twentieth century changing gully morphologies. As the results show, large-scale land-cover changes and deforestation cannot explain the observed processes. The study therefore invokes interactions between authigenic factors, small-scale plot boundary changes, cropland management and sociopolitical forces to explain the gully cut processes. Finally, semi-structured interviews and sedistratigraphic analysis of three filled gullies confirm the dominant impact of (crop)land management (tillage, check dams in gullies and channel diversions) on gully cut-and-fill processes. Since agricultural land management – including land tenure and land distribution – has been commonly neglected in earlier related research, we argue therefore that it can be a very strong driver of twentieth century gully morphodynamics

Cellular Automata as Microscopic Models of Cell Migration in Heterogeneous Environments

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High precision X-ray logN-logS distributions: implications for the obscured AGN population

We have constrained the extragalactic source count distributions over a broad range of X-ray fluxes and in various energy bands to test whether the predictions from X-ray background synthesis models agree with the observational constraints provided by our measurements. We have used 1129 XMM-Newton observations at |b|>20 deg covering a sky area of 132.3 deg^2 to compile the largest complete samples of X-ray objects to date in the 0.5-1 keV, 1-2 keV, 2-4.5 keV, 4.5-10 keV, 0.5-2 keV and 2-10 keV energy bands. Our survey includes in excess of 30,000 sources down to ~10^-15 erg/cm^2/s below 2 keV and down to ~10^{-14} erg/cm^2/s above 2 keV. A break in the source count distributions was detected in all energy bands except the 4.5-10 keV band. An analytical model comprising 2 power-law components cannot adequately describe the curvature seen in the source count distributions. The shape of the logN(>S)-logS is strongly dependent on the energy band with a general steepening apparent as we move to higher energies. This is due to non-AGN populations, comprised mainly of stars and clusters of galaxies, contribute up to 30% of the source population at energies 10^{-13} erg/cm^2/s, and these populations of objects have significantly flatter source count distributions than AGN. We find a substantial increase in the relative fraction of hard X-ray sources at higher energies, from >55% below 2 keV to >77% above 2 keV. However the majority of sources detected above 4.5 keV still have significant flux below 2 keV. Comparison with predictions from the synthesis models suggest that the models might be overpredicting the number of faint absorbed AGN, which would call for fine adjustment of some model parameters such as the obscured to unobscured AGN ratio and/or the distribution of column densities at intermediate obscuration.Comment: Accepted for publication in Astronomy and Astrophysics. Abridged Abstract. 23 pages, 47 figures, 8 table

A radio-emitting outflow produced by the tidal disruption event AT2020vwl

A tidal disruption event (TDE) occurs when a star is destroyed by a supermassive black hole. Broadband radio spectral observations of TDEs trace the emission from any outflows or jets that are ejected from the vicinity of the supermassive black hole. However, radio detections of TDEs are rare, with less than 20 published to date, and only 11 with multi-epoch broadband coverage. Here we present the radio detection of the TDE AT2020vwl and our subsequent radio monitoring campaign of the outflow that was produced, spanning 1.5 years post-optical flare. We tracked the outflow evolution as it expanded between $10^{16}$ cm to $10^{17}$ cm from the supermassive black hole, deducing it was non-relativistic and launched quasi-simultaneously with the initial optical detection through modelling the evolving synchrotron spectra of the event. We deduce that the outflow is likely to have been launched by material ejected from stream-stream collisions (more likely), the unbound debris stream, or an accretion-induced wind or jet from the supermassive black hole (less likely). AT2020vwl joins a growing number of TDEs with well-characterised prompt radio emission, with future timely radio observations of TDEs required to fully understand the mechanism that produces this type of radio emission in TDEs.Comment: 15 pages, 9 figures, accepted for publication in MNRA