Influence of processing methods on the quality attributes of bio-fortified sweet potato products

Bio-fortified sweet potato (BSP) is one of the crops that can be used to address the problems of vitamin A deficiency in the Sub-Saharan Africa but it’s currently being underutilized. This study seeks to evaluate the effects of different heat processing methods on the quality of products made from BSP in order to increase its utilization. Freshly harvested tubers were purchased from a Research Farm in Federal University of Agriculture, Abeokuta (FUNAAB), Nigeria and brought to the Processing Centre, Nigerian Stored Products Research Institute (NSPRI), Ilorin. The sample was taken through some standard pre-processing operations of sorting, peeling, washing, slicing (2.11 mm), and deep frying (3 minutes) while some portions were boiled immediately after sorting with or without skin for 10–15 minutes. Each treated sample was analysed for sensory, proximate, vitamins and mineral compositions following standard methods. Results showed that fried sample had highest acceptability for aroma (7.25) and crispiness (7.00) while sample boiled without skin (15 min) was rated with least scores in colour (5.30), appearance (5.40), texture (4.95), crispiness (4.65) and overall acceptability (5.70). Protein, vitamin C, phenolics, flavonoids and reducing sugar contents were 6.53–18.52%, 10.89–76.69 mg/100 g, 0.57–3.15 mg/L, 94.64–383.91 mg/L and 43.05–237.12 g/100 g respectively while some minerals such as Na, K and Zn ranged from 8.42–17.45, 5.12–9.30 and 0.03–0.09 mg/L respectively. Different heat processing at different durations affected the sensory attributes, nutritional and mineral compositions of BSP. Key words: Post-harvest, food security, potato, heat treatment, qualit

First principles of modelling the stabilization of microturbulence by fast ions

The observation that fast ions stabilize ion-temperature-gradient-driven microturbulence has profound implications for future fusion reactors. It is also important in optimizing the performance of present-day devices. In this work, we examine in detail the phenomenology of fast ion stabilization and present a reduced model which describes this effect. This model is derived from the high-energy limit of the gyrokinetic equation and extends the existing ‘dilution’ model to account for nontrivial fast ion kinetics. Our model provides a physicallytransparent explanation for the observed stabilization and makes several key qualitative predictions. Firstly, that different classes of fast ions, depending on their radial density or temperature variation, have different stabilizing properties. Secondly, that zonal flows are an important ingredient in this effect precisely because the fast ion zonal response is negligible. Finally, that in the limit of highly-energetic fast ions, their response approaches that of the ‘dilution’ model; in particular, alpha particles are expected to have little, if any, stabilizing effect on plasma turbulence. We support these conclusions through detailed linear and nonlinear gyrokinetic simulations

Transverse momentum spectra of charged particles in proton-proton collisions at s=900\sqrt{s} = 900 GeV with ALICE at the LHC

The inclusive charged particle transverse momentum distribution is measured in proton-proton collisions at $\sqrt{s} = 900$ GeV at the LHC using the ALICE detector. The measurement is performed in the central pseudorapidity region $(|\eta|<0.8)$ over the transverse momentum range $0.15<p_{\rm T}<10$ GeV/$c$. The correlation between transverse momentum and particle multiplicity is also studied. Results are presented for inelastic (INEL) and non-single-diffractive (NSD) events. The average transverse momentum for $|\eta|<0.8$ is $\left<p_{\rm T}\right>_{\rm INEL}=0.483\pm0.001$ (stat.) $\pm0.007$ (syst.) GeV/$c$ and \left_{\rm NSD}=0.489\pm0.001 (stat.) $\pm0.007$ (syst.) GeV/$c$, respectively. The data exhibit a slightly larger $\left<p_{\rm T}\right>$ than measurements in wider pseudorapidity intervals. The results are compared to simulations with the Monte Carlo event generators PYTHIA and PHOJET.Comment: 20 pages, 8 figures, 2 tables, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/390

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged symptoms termed long coronavirus disease (COVID), yet disease phenotypes and mechanisms are poorly understood1. Here we profiled 368 plasma proteins in 657 participants ≥3 months following hospitalization. Of these, 426 had at least one long COVID symptom and 233 had fully recovered. Elevated markers of myeloid inflammation and complement activation were associated with long COVID. IL-1R2, MATN2 and COLEC12 were associated with cardiorespiratory symptoms, fatigue and anxiety/depression; MATN2, CSF3 and C1QA were elevated in gastrointestinal symptoms and C1QA was elevated in cognitive impairment. Additional markers of alterations in nerve tissue repair (SPON-1 and NFASC) were elevated in those with cognitive impairment and SCG3, suggestive of brain–gut axis disturbance, was elevated in gastrointestinal symptoms. Severe acute respiratory syndrome coronavirus 2-specific immunoglobulin G (IgG) was persistently elevated in some individuals with long COVID, but virus was not detected in sputum. Analysis of inflammatory markers in nasal fluids showed no association with symptoms. Our study aimed to understand inflammatory processes that underlie long COVID and was not designed for biomarker discovery. Our findings suggest that specific inflammatory pathways related to tissue damage are implicated in subtypes of long COVID, which might be targeted in future therapeutic trials

SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

BACKGROUND: Most studies of immunity to SARS-CoV-2 focus on circulating antibody, giving limited insights into mucosal defences that prevent viral replication and onward transmission. We studied nasal and plasma antibody responses one year after hospitalisation for COVID-19, including a period when SARS-CoV-2 vaccination was introduced. METHODS: In this follow up study, plasma and nasosorption samples were prospectively collected from 446 adults hospitalised for COVID-19 between February 2020 and March 2021 via the ISARIC4C and PHOSP-COVID consortia. IgA and IgG responses to NP and S of ancestral SARS-CoV-2, Delta and Omicron (BA.1) variants were measured by electrochemiluminescence and compared with plasma neutralisation data. FINDINGS: Strong and consistent nasal anti-NP and anti-S IgA responses were demonstrated, which remained elevated for nine months (p < 0.0001). Nasal and plasma anti-S IgG remained elevated for at least 12 months (p < 0.0001) with plasma neutralising titres that were raised against all variants compared to controls (p < 0.0001). Of 323 with complete data, 307 were vaccinated between 6 and 12 months; coinciding with rises in nasal and plasma IgA and IgG anti-S titres for all SARS-CoV-2 variants, although the change in nasal IgA was minimal (1.46-fold change after 10 months, p = 0.011) and the median remained below the positive threshold determined by pre-pandemic controls. Samples 12 months after admission showed no association between nasal IgA and plasma IgG anti-S responses (R = 0.05, p = 0.18), indicating that nasal IgA responses are distinct from those in plasma and minimally boosted by vaccination. INTERPRETATION: The decline in nasal IgA responses 9 months after infection and minimal impact of subsequent vaccination may explain the lack of long-lasting nasal defence against reinfection and the limited effects of vaccination on transmission. These findings highlight the need to develop vaccines that enhance nasal immunity. FUNDING: This study has been supported by ISARIC4C and PHOSP-COVID consortia. ISARIC4C is supported by grants from the National Institute for Health and Care Research and the Medical Research Council. Liverpool Experimental Cancer Medicine Centre provided infrastructure support for this research. The PHOSP-COVD study is jointly funded by UK Research and Innovation and National Institute of Health and Care Research. The funders were not involved in the study design, interpretation of data or the writing of this manuscript

Faraday dichroic beam splitter for Raman light using an isotopically pure alkali-metal-vapor cell

We present an application of the Faraday effect to produce a narrow band atomic filter in an alkali metal vapor. In our experiment two Raman beams separated in frequency by the ground state hyperfine splitting in 87Rb are produced using an EOM and then filtered using the Faraday effect in an isotopically pure 85Rb thermal vapor. An experimental transmission spectra for the filter is presented along with a theoretical calculation. The performance of the filter is then demonstrated and characterized using a Fabry-Perot etalon. For a temperature of 70 degrees and a longitudinal magnetic field of 80 G a suppression to -18 dB is achieved, limited by the quality of the polarizers.Comment: 3 pages, 3 figure

Chemical and physico-chemical properties of orange fleshed sweet potatoes (OFSP) chips dried using solar dyers

In this study, drying technology was employed to process fresh orange fleshed sweet potatoes (OFSP) into dried slices using NSPRI improved solar tent dryer, parabolic shaped solar tent dryer in comparison with open air drying and its effect on the chemical, physico-chemical and mineral constituents of dried OFSP slices was investigated. Results showed that the dried-OFSP contained ash (3.69-4.09 %), fat (4.09-5.09 %), crude fibre (4.69-5.15 %), protein (5.87-8.28 %), carbohydrate (78.22-82.21 %), vitamin C (8.55-20.49 mg/100g), phenolics (0.1-1.28 mg/kg), flavonoids (984-145 mg/kg) and reducing sugar (35.01-82.23 g/100g). The total titratable acidity of the dried OFSP slices varied between 0.56-0.89 %, total soluble solids ranged between 5.70-7.00 °Brix while pH ranged between 4.94-6.47. Zinc, magnesium, potassium, calcium, sodium, iron were present in varying levels but aluminium, lead and cadmium were not detected in all the samples. This study therefore showed that good quality dried OFSP slices with appreciable nutrient content can be obtained from drying in NSPRI solar tent dryers especially with the use of the parabolic shaped solar tent dryer. Thus, the parabolic solar tent dryer is recommended for drying crops. Keywords: Drying technology, Orange fleshed sweet potato, NSPRI solar dyers, Physicochemical propertie

Performance characteristics of broilers fed graded levels of Moringa oleifera leaf meal

Cost of conventional protein sources is on the increase recently; hence, there is the need for cheaper alternative sources that will not compromise the performance characteristics of broiler birds taking into consideration the cost of production. Moringa leaf meal has been reported to increase the performance of broiler birds due to its rich protein content. Two hundred day-old broiler chicks were used to assess the effects of partial replacement of soya bean meal with Moringa (Moringa oleifera) leaf meal on broiler chickens in an 8-wk feeding trial. The birds were randomly assigned in equal numbers into five dietary treatments: 0, 5, 10, 15, and 20 % Moringa leaf meal (MOLM). Each treatment was replicated four times with 10 birds per replicate. The results showed that final weight, weight gain, daily weight gain, total feed intake, daily feed intake and feed conversion ratio were significantly (p0.05) effect on primal cut parts and relative organ weight. From the results of this study, replacement of soybean meal with MOLM up to 20% did not have any adverse effect on growth performance and carcass traits of broiler chickens