26 research outputs found

    Es necesario rotular con más claridad los tubos emisores de luz ultravioleta C para la prevención de lesiones en la piel y los ojos

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    La queratoconjuntivitis actínica se produce por la exposición del ojo sin protección a los rayos ultravioleta, sobre todo de los tipos B y C (UV-B y UV-C). Consiste en una inflamación superficial del ojo muy molesta, que produce sensación de cuerpo extraño, dolor, lagrimeo y fotofobia, con una duración de 12-24 horas. Normalmente no hay secuelas, aunque en ocasiones pueden producirse úlceras corneales. En la mayoría de los casos se debe al uso de equipos de soldadura o a focos de luz potentes..

    Association of a single nucleotide polymorphism combination pattern of the Klotho gene with non-cardiovascular death in patients with chronic kidney disease

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    Chronic kidney disease (CKD) is associated with an elevated risk of all-cause mortality, with cardiovascular death being extensively investigated. However, non-cardiovascular mortality represents the biggest percentage, showing an evident increase in recent years. Klotho is a gene highly expressed in the kidney, with a clear influence on lifespan. Low levels of Klotho have been linked to CKD progression and adverse outcomes. Single nucleotide polymorphisms (SNPs) of the Klotho gene have been associated with several diseases, but studies investigating the association of Klotho SNPs with noncardiovascular death in CKD populations are lacking. The main aim of this study was to assess whether 11 Klotho SNPs were associated with non-cardiovascular death in a subpopulation of the National Observatory of Atherosclerosis in Nephrology (NEFRONA) study (n ¼ 2185 CKD patients). After 48 months of follow-up, 62 cardiovascular deaths and 108 non-cardiovascular deaths were recorded. We identified a high non-cardiovascular death risk combination of SNPs corresponding to individuals carrying the most frequent allele (G) at rs562020, the rare allele (C) at rs2283368 and homozygotes for the rare allele (G) at rs2320762 (rs562020 GG/AG þ rs2283368 CC/CT þ rs2320762 GG). Among the patients with the three SNPs genotyped (n ¼ 1016), 75 (7.4%) showed this combination. Furthermore, 95 (9.3%) patients showed a low-risk combination carrying all the opposite genotypes (rs562020 AA þ rs2283368 TT þ rs2320762 GT/TT). All the other combinations [n ¼ 846 (83.3%)] were considered as normal risk. Using competing risk regression analysis, we confirmed that the proposed combinations are independently associated with a higher fhazard ratio [HR] 3.28 [confidence interval (CI) 1.51-7.12]g and lower [HR 6 × 10- (95% CI 3.3 × 10--1.1 × 10-)] risk of suffering a non-cardiovascular death in the CKD population of the NEFRONA cohort compared with patients with the normal-risk combination. Determination of three SNPs of the Klotho gene could help in the prediction of non-cardiovascular death in CKD

    Readout technologies for directional WIMP Dark Matter detection

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    The measurement of the direction of WIMP-induced nuclear recoils is a compelling but technologically challenging strategy to provide an unambiguous signature of the detection of Galactic dark matter. Most directional detectors aim to reconstruct the dark-matter-induced nuclear recoil tracks, either in gas or solid targets. The main challenge with directional detection is the need for high spatial resolution over large volumes, which puts strong requirements on the readout technologies. In this paper we review the various detector readout technologies used by directional detectors. In particular, we summarize the challenges, advantages and drawbacks of each approach, and discuss future prospects for these technologies

    Compte-rendu de lecture de l'ouvrage Green G.P, Deller S., Marcouiller D., Amenities and rural development : theory , methods and public policies, Edward Elgar, 2005, 338 p.

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    AutresThis work gathers contributions presented at a conference on the amenities and the rural development which was taken place in Madison during the summer 2004. It calls upon several disciplines like the economy, sociology, the geography and installation. The work tackles successively the theoretical problems related to the concept of amenities and in particular those associated their offer and with their request, develops some methodological and empirical questions related to the measurement of the impact of the amenities about the rural development, then briefly described the consequences for the public decision.Cet ouvrage regroupe des contributions présentées à une conférence sur les aménités et le développement rural qui s'est tenue à Madison durant l'été 2004 . Il fait appel à plusieurs disciplines comme l'économie, la sociologie, la géographie et l'aménagement. L'ouvrage aborde successivement les problèmes théoriques liés au concept d'aménités et en particulier ceux associés à leur offre et à leur demande, développe quelques questions méthodologiques et empiriques liées à la mesure de l'impact des aménités sur le développement rural, puis décrit brièvement les conséquences pour la décision publique
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