Upregulation of peroxisome proliferator-activated receptor gamma coactivator gene ( PGC1A ) during weight loss is related to insulin sensitivity but not to energy expenditure

Aims/hypothesis: We investigated whether skeletal muscle peroxisome proliferator-activated receptor gamma coactivator-1 (PGC1A; also known as PPARGC1A) and its target mitofusin-2 (MFN2), as well as carnitine palmitoyltransferase-1 (CPT1; also known as carnitine palmitoyltransferase 1A [liver] [CPT1A]) and uncoupling protein (UCP)3, are involved in the improvement of insulin resistance and/or in the modification of energy expenditure during surgically induced massive weight loss. Materials and methods: Seventeen morbidly obese women (mean BMI: 45.9 ± 4kg/m2) were investigated before, and 3 and 12months after, Roux-en-Y gastric bypass (RYGB). We evaluated insulin sensitivity by the euglycaemic-hyperinsulinaemic clamp, energy expenditure and substrate oxidation by indirect calorimetry, and muscle mRNA expression by PCR. Results: Post-operatively, PGC1A was enhanced at 3 (p = 0.02) and 12months (p = 0.03) as was MFN2 (p = 0.008 and p = 0.03 at 3 and 12months respectively), whereas UCP3 was reduced (p = 0.03) at 12months. CPT1 did not change. The expression of PGC1A and MFN2 were strongly (p < 0.0001) related. Insulin sensitivity, which increased after surgery (p = 0.002 at 3, p = 0.003 at 12months), was significantly related to PGC1A and MFN2, but only MFN2 showed an independent influence in a multiple regression analysis. Energy expenditure was reduced at 3months post-operatively (p = 0.001 vs before RYGB), remaining unchanged thereafter until 12months. CPT1 and UCP3 were not significantly related to the modifications of energy expenditure or of lipid oxidation rate. Conclusions/interpretation: Weight loss upregulates PGC1A, which in turn stimulates MFN2 expression. MFN2 expression significantly and independently contributes to the improvement of insulin sensitivity. UCP3 and CPT1 do not seem to influence energy expenditure after RYG

The Distance of the First Overtone RR Lyrae Variables in the MACHO LMC Database: A New Method to Correct for the Effects of Crowding

Previous studies have indicated that many of the RR Lyrae variables in the LMC have properties similar to the ones in the Galactic globular cluster M3. Assuming that the M3 RR Lyrae variables follow the same relationships among period, temperature, amplitude and Fourier phase parameter phi31 as their LMC counterparts, we have used the M3 phi31-logP relation to identify the M3-like unevolved first overtone RR Lyrae variables in 16 fields near the LMC bar. The temperatures of these variables were calculated from the M3 logP-logTe relation so that the extinction could be derived for each star separately. Since blended stars have lower amplitudes for a given period, the period amplitude relation should be a useful tool for identifying which stars are affected by crowding. We find that the low amplitude stars are brighter. We remove them from the sample and derive an LMC distance modulus 18.49+/-0.11.Comment: 30 pages, 7 figures, accepted for publication in the Astronomical Journa

HFF-DeepSpace photometric catalogs of the 12 Hubble frontier fields, clusters, and parallels : photometry, photometric redshifts, and stellar masses

We present Hubble multi-wavelength photometric catalogs, including (up to) 17 filters with the Advanced Camera for Surveys and Wide Field Camera 3 from the ultra-violet to near-infrared for the Hubble Frontier Fields and associated parallels. We have constructed homogeneous photometric catalogs for all six clusters and their parallels. To further expand these data catalogs, we have added ultra-deep KS-band imaging at 2.2. mu m from the Very Large Telescope HAWK-I and Keck-I MOSFIRE instruments. We also add post-cryogenic Spitzer imaging at 3.6 and 4.5. mu m with the Infrared Array Camera (IRAC), as well as archival IRAC 5.8 and 8.0. mu m imaging when available. We introduce the public release of the multi-wavelength (0.2-8 mu m) photometric catalogs, and we describe the unique steps applied for the construction of these catalogs. Particular emphasis is given to the source detection band, the contamination of light from the bright cluster galaxies (bCGs), and intra-cluster light (ICL). In addition to the photometric catalogs, we provide catalogs of photometric redshifts and stellar population properties. Furthermore, this includes all the images used in the construction of the catalogs, including the combined models of bCGs and ICL, the residual images, segmentation maps, and more. These catalogs are a robust data set of the Hubble Frontier Fields and will be an important aid in designing future surveys, as well as planning follow-up programs with current and future observatories to answer key questions remaining about first light, reionization, the assembly of galaxies, and many more topics, most notably by identifying high-redshift sources to target

The importance of major mergers in the build up of stellar mass in brightest cluster galaxies at z=1

Recent independent results from numerical simulations and observations have shown that brightest cluster galaxies (BCGs) have increased their stellar mass by a factor of almost two between z~0.9 and z~0.2. The numerical simulations further suggest that more than half this mass is accreted through major mergers. Using a sample of 18 distant galaxy clusters with over 600 spectroscopically confirmed cluster members between them, we search for observational evidence that major mergers do play a significant role. We find a major merger rate of 0.38 +/- 0.14 mergers per Gyr at z~1. While the uncertainties, which stem from the small size of our sample, are relatively large, our rate is consistent with the results that are derived from numerical simulations. If we assume that this rate continues to the present day and that half of the mass of the companion is accreted onto the BCG during these mergers, then we find that this rate can explain the growth in the stellar mass of the BCGs that is observed and predicted by simulations. Major mergers therefore appear to be playing an important role, perhaps even the dominant one, in the build up of stellar mass in these extraordinary galaxies.Comment: 15 pages, 6 figures, accepted for publication in MNRAS. Reduced data will be made available through the ESO archiv

Satellite content and quenching of star formation in galaxy groups at z ~ 1.8

We study the properties of satellites in the environment of massive star-forming galaxies at z ~ 1.8 in the COSMOS field, using a sample of 215 galaxies on the main sequence of star formation with an average mass of ~1011M⊙. At z> 1.5, these galaxies typically trace halos of mass ≳1013M⊙. We use optical-near-infrared photometry to estimate stellar masses and star formation rates (SFR) of centrals and satellites down to ~ 6 × 109M⊙. We stack data around 215 central galaxies to statistically detect their satellite halos, finding an average of ~3 galaxies in excess of the background density. We fit the radial profiles of satellites with simple β-models, and compare their integrated properties to model predictions. We find that the total stellar mass of satellites amounts to ~68% of the central galaxy, while spectral energy distribution modeling and far-infrared photometry consistently show their total SFR to be 25-35% of the central's rate. We also see significant variation in the specific SFR of satellites within the halo with, in particular, a sharp decrease at <100 kpc. After considering different potential explanations, we conclude that this is likely an environmental signature of the hot inner halo. This effect can be explained in the first order by a simple free-fall scenario, suggesting that these low-mass environments can shut down star formation in satellites on relatively short timescales of ~0.3 Gyr

Satellite quenching was not important for z ∼ 1 clusters: most quenching occurred during infall

We quantify the relative importance of environmental quenching versus pre-processing in z ∼ 1 clusters by analysing the infalling galaxy population in the outskirts of 15 galaxy clusters at 0.8 1011 M⊙ were quenched prior to infall, while up to half of lower mass galaxies were environmentally quenched after passing the virial radius. This means most of the massive quiescent galaxies in z ∼ 1 clusters were self-quenched or pre-processed prior to infall

The star formation history of BCGs to z = 1.8 from the SpARCS/SWIRE survey : evidence for significant in situ star formation at high redshift

We present the results of an MIPS-24 μm study of the brightest cluster galaxies (BCGs) of 535 high-redshift galaxy clusters. The clusters are drawn from the Spitzer Adaptation of the Red-Sequence Cluster Survey, which effectively provides a sample selected on total stellar mass, over 0.2 12) increases rapidly with redshift. Above z ∼ 1, an average of ∼20% of the sample have 24 μm inferred infrared luminosities of LIR > 1012 Lo, while the fraction below z ∼ 1 exhibiting such luminosities is <1%. The Spitzer-IRAC colors indicate the bulk of the 24 μm detected population is predominantly powered by star formation, with only 7/125 galaxies lying within the color region inhabited by active galactic nuclei (AGNs). Simple arguments limit the star formation activity to several hundred million years and this may therefore be indicative of the timescale for AGN feedback to halt the star formation. Below redshift z ∼ 1, there is not enough star formation to significantly contribute to the overall stellar mass of the BCG population, and therefore BCG growth is likely dominated by dry mergers. Above z ∼ 1, however, the inferred star formation would double the stellar mass of the BCGs and is comparable to the mass assembly predicted by simulations through dry mergers. We cannot yet constrain the process driving the star formation for the overall sample, though a single object studied in detail is consistent with a gas-rich merger.Peer reviewe

THE VLT LEGA-C spectroscopic survey:the physics of galaxies at a lookback time of 7 Gyr

The Large Early Galaxy Census (LEGA-C) is a Public Spectroscopic Survey of ~3200 K-band selected galaxies at redshifts z = 0.6 − 1.0 with stellar masses ${M}_{*}\gt {10}^{10}\quad {M}_{\odot }$, conducted with VIMOS on ESO's Very Large Telescope. The survey is embedded in the COSMOS field (R.A. = 10h00; $\mathrm{decl}.\;=\;+2\;\mathrm{deg}$). The 20 hr long integrations produce high-signal-to-noise ratio continuum spectra that reveal ages, metallicities and velocity dispersions of the stellar populations. LEGA-C's unique combination of sample size and depth will enable us for the first time to map the stellar content at large lookback time, across galaxies of different types and star formation activity. Observations started in 2014 December and are planned to be completed by mid 2018, with early data releases of the spectra and value-added products. In this paper we present the science case, the observing strategy, an overview of the data reduction process and data products, and a first look at the relationship between galaxy structure and spectral properties, as it existed 7 Gyr ago

Radio selection of the most distant galaxy clusters

We show that the most distant X-ray detected cluster known to date, ClJ1001 at z=2.506, hosts a strong overdensity of radio sources. Six of them are individually detected (within 10") in deep 0.75" resolution VLA 3GHz imaging, with S(3GHz)>8uJy. Of the six, AGN likely affects the radio emission in two galaxies while star formation is the dominant source powering the remaining four. We searched for cluster candidates over the full COSMOS 2-square degree field using radio-detected 3GHz sources and looking for peaks in Sigma5 density maps. ClJ1001 is the strongest overdensity by far with >10sigma, with a simple z_phot>1.5 preselection. A cruder photometric rejection of z2.5. Samples of hundreds such high-redshift clusters could potentially constrain cosmological parameters and test cluster and galaxy formation models

The Star-Formation Histories of z~2 DOGs and SMGs

The Spitzer Space Telescope has identified a population of ultra-luminous infrared galaxies (ULIRGs) at z ~ 2 that may play an important role in the evolution of massive galaxies. We measure the stellar masses of two populations of Spitzer-selected ULIRGs, both of which have extremely red R-[24] colors (dust-obscured galaxies, or DOGs) and compare our results with sub-millimeter selected galaxies (SMGs). One set of 39 DOGs has a local maximum in their mid-IR spectral energy distribution (SED) at rest-frame 1.6um associated with stellar emission ("bump DOGs"), while the other set of 51 DOGs has a power-law dominated mid-IR SED with spectral features typical of obscured AGN ("power-law DOGs"). We use stellar population synthesis models applied self-consistently to broad-band photometry in the rest-frame ultra-violet, optical, and near-infrared of each of these populations and test a variety of stellar population synthesis codes, star-formation histories (SFHs), and initial mass functions (IMFs). Assuming a simple stellar population SFH and a Chabrier IMF, we find that the median and inner quartile stellar masses of SMGs, bump DOGs and power-law DOGs are given by log(M_*/M_sun) = 10.42_-0.36^+0.42, 10.62_-0.32^+0.36, and 10.71_-0.34^+0.40, respectively. Implementing more complicated SFHs with multiple age components increases these mass estimates by up to 0.5 dex. Our stellar mass estimates are consistent with physical mechanisms for the origin of z~2 ULIRGs that result in high star-formation rates for a given stellar mass. Such mechanisms are usually driven by a major merger of two gas-rich systems, rather than smooth accretion of gas and small satellites.Comment: 17 pages, 7 figures, 3 tables. Plus figures showing SEDs and best-fit synthesized stellar population model. Accepted to the Ap