Mass-independent scheme for enhancing spatial quantum superpositions

Placing a large mass in a large spatial superposition, such as a Schrödinger cat state, is a significant and important challenge. In particular, the large spatial superposition [O(10-100)μm] of mesoscopic masses [m∼O(10-14-10-15)kg] makes it possible to test the quantum nature of gravity via entanglement in the laboratory. To date, the proposed methods of achieving this spatial delocalization are to use wave-packet expansions or quantum ancilla- (for example, spin-) dependent forces, all of whose efficacy reduces with mass. Thus increasing the spatial splitting independently of the mass is an important open challenge. In this paper we present a method of achieving a mass-independent enhancement of superposition via diamagnetic repulsion from current-carrying wires. We analyze an example system which uses the Stern-Gerlach effect to creating a small initial splitting and then apply our diamagnetic repulsion method to enhance the superposition size O(400-600)μm from an initial modest split of the wave function. We provide an analytical and numerical analysis of our scheme

Quantum gravitational sensor for space debris

Matter-wave interferometers have fundamental applications for gravity experiments such as testing the equivalence principle and the quantum nature of gravity. In addition, matter-wave interferometers can be used as quantum sensors to measure the local gravitational acceleration caused by external massive moving objects, thus lending itself for technological applications. In this paper, we will establish a three-dimensional model to describe the gravity gradient signal from an external moving object, and theoretically investigate the achievable sensitivities using the matter-wave interferometer based on the Stern-Gerlach setup. As an application we will consider the mesoscopic interference for metric and curvature and gravitational-wave detection scheme [R. J. Marshman, Mesoscopic interference for metric and curvature (MIMAC) & gravitational wave detection, New J. Phys. 22, 083012 (2020)NJOPFM1367-263010.1088/1367-2630/ab9f6c] and quantify its sensitivity to gravity gradients using frequency-space analysis. We will consider objects near Earth-based experiments and space debris in proximity of satellites and estimate the minimum detectable mass of the object as a function of their distance, velocity, and orientation

Gravitational optomechanics: Photon-matter entanglement via graviton exchange

The deflection of light in the gravitational field of the Sun is one of the most fundamental consequences for general relativity as well as one of its classical tests first performed by Eddington a century ago. However, despite its center stage role in modern physics, no experiment has tested it in an ostensibly quantum regime where both matter and light exhibit nonclassical features. This paper shows that the interaction which gives rise to the light-bending also induces photon-matter entanglement as long as gravity and matter are treated at par with quantum mechanics. The quantum light-bending interaction within the framework of perturbative quantum gravity highlights this point by showing that the entangled states can be generated already with coherent states of light and matter exploiting the nonlinear coupling induced by graviton exchange. Furthermore, the quantum light-bending interaction is capable of discerning between the spin-2 and spin-0 gravitons thus also providing a test for alternative theories of gravity at short distances and at the quantum level. We will conclude by estimating the order of magnitude of the entanglement generated by employing the linear entropy. In particular, we find that a half-ring cavity of radius 0.25 m placed around a 10 kg mechanical oscillator operating at 150 Hz, could be used to generate linear entropy of order unity using a petawatt laser source at optical wavelengths. While the proposed scheme is beyond the current experimental realities it nonetheless initiates the discussion about testing the spin of the gravitational interaction at the quantum level

Relative Acceleration Noise Mitigation for Nanocrystal Matter-wave Interferometry: Application to Entangling Masses via Quantum Gravity

Matter wave interferometers with large momentum transfers, irrespective of specific implementations, will face a universal dephasing due to relative accelerations between the interferometric mass and the associated apparatus. Here we propose a solution that works even without actively tracking the relative accelerations: putting both the interfering mass and its associated apparatus in a freely falling capsule, so that the strongest inertial noise components vanish due to the equivalence principle. In this setting, we investigate two of the most important remaining noise sources: (a) the non-inertial jitter of the experimental setup and (b) the gravity-gradient noise. We show that the former can be reduced below desired values by appropriate pressures and temperatures, while the latter can be fully mitigated in a controlled environment. We finally apply the analysis to a recent proposal for testing the quantum nature of gravity [S. Bose et. al. Phys. Rev. Lett 119, 240401 (2017)] through the entanglement of two masses undergoing interferometry. We show that the relevant entanglement witnessing is feasible with achievable levels of relative acceleration noise

Realization of a complete Stern-Gerlach interferometer: Toward a test of quantum gravity

The Stern-Gerlach effect, found a century ago, has become a paradigm of quantum mechanics. Unexpectedly, until recently, there has been little evidence that the original scheme with freely propagating atoms exposed to gradients from macroscopic magnets is a fully coherent quantum process. Several theoretical studies have explained why a Stern-Gerlach interferometer is a formidable challenge. Here, we provide a detailed account of the realization of a full-loop Stern-Gerlach interferometer for single atoms and use the acquired understanding to show how this setup may be used to realize an interferometer for macroscopic objects doped with a single spin. Such a realization would open the door to a new era of fundamental probes, including the realization of previously inaccessible tests at the interface of quantum mechanics and gravity

Spin Entanglement Witness for Quantum Gravity

Understanding gravity in the framework of quantum mechanics is one of the great challenges in modern physics. However, the lack of empirical evidence has lead to a debate on whether gravity is a quantum entity. Despite varied proposed probes for quantum gravity, it is fair to say that there are no feasible ideas yet to test its quantum coherent behavior directly in a laboratory experiment. Here, we introduce an idea for such a test based on the principle that two objects cannot be entangled without a quantum mediator. We show that despite the weakness of gravity, the phase evolution induced by the gravitational interaction of two micron size test masses in adjacent matter-wave interferometers can detectably entangle them even when they are placed far apart enough to keep Casimir-Polder forces at bay. We provide a prescription for witnessing this entanglement, which certifies gravity as a quantum coherent mediator, through simple spin correlation measurements

Testing the Quantum Coherent Behaviour of Gravity

Although quantum gravity is a highly pursued research topic, the more basic question of whether gravity is quantum has not yet been answered. Here we present a table-top experiment, feasible with forseeable advances in technology, which can demonstrate that the Newtonian field from an object is a bonafide quantum entity. This is demonstrated through the development of a verifiable entanglement between two matter wave interferometers with mesoscopic objects as entanglement between systems which are not directly interacting, can only be mediated by a quantum system

Hepatitis C virus infection upregulates CD55 expression on the hepatocyte surface and promotes association with virus particles

CD55 limits excessive complement activation on the host cell surface by accelerating the decay of C3 convertases. In this study, we observed that hepatitis C virus (HCV) infection of hepatocytes or HCV core protein expression in transfected hepatocytes upregulated CD55 expression at the mRNA and protein levels. Further analysis suggested that the HCV core protein or full-length (FL) genome enhanced CD55 promoter activity in a luciferase-based assay, which was further augmented in the presence of interleukin-6. Mutation of the CREB or SP-1 binding site on the CD55 promoter impaired HCV core protein-mediated upregulation of CD55. HCV-infected or core protein-transfected Huh7.5 cells displayed greater viability in the presence of CD81 and CD55 antibodies and complement. Biochemical analysis revealed that CD55 was associated with cell culture-grown HCV after purification by sucrose density gradient ultracentrifugation. Consistent with this, a polyclonal antibody to CD55 captured cell culture-grown HCV. Blocking antibodies against CD55 or virus envelope glycoproteins in the presence of normal human serum as a source of complement inhibited HCV infection. The inhibition was enhanced in the presence of both the antibodies and serum complement. Collectively, these results suggest that HCV induces and associates with a negative regulator of the complement pathway, a likely mechanism for immune evasion

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE

Combined search for the quarks of a sequential fourth generation

Results are presented from a search for a fourth generation of quarks produced singly or in pairs in a data set corresponding to an integrated luminosity of 5 inverse femtobarns recorded by the CMS experiment at the LHC in 2011. A novel strategy has been developed for a combined search for quarks of the up and down type in decay channels with at least one isolated muon or electron. Limits on the mass of the fourth-generation quarks and the relevant Cabibbo-Kobayashi-Maskawa matrix elements are derived in the context of a simple extension of the standard model with a sequential fourth generation of fermions. The existence of mass-degenerate fourth-generation quarks with masses below 685 GeV is excluded at 95% confidence level for minimal off-diagonal mixing between the third- and the fourth-generation quarks. With a mass difference of 25 GeV between the quark masses, the obtained limit on the masses of the fourth-generation quarks shifts by about +/- 20 GeV. These results significantly reduce the allowed parameter space for a fourth generation of fermions.Comment: Replaced with published version. Added journal reference and DO