Matter-wave interferometers have fundamental applications for gravity experiments such as testing the equivalence principle and the quantum nature of gravity. In addition, matter-wave interferometers can be used as quantum sensors to measure the local gravitational acceleration caused by external massive moving objects, thus lending itself for technological applications. In this paper, we will establish a three-dimensional model to describe the gravity gradient signal from an external moving object, and theoretically investigate the achievable sensitivities using the matter-wave interferometer based on the Stern-Gerlach setup. As an application we will consider the mesoscopic interference for metric and curvature and gravitational-wave detection scheme [R. J. Marshman, Mesoscopic interference for metric and curvature (MIMAC) & gravitational wave detection, New J. Phys. 22, 083012 (2020)NJOPFM1367-263010.1088/1367-2630/ab9f6c] and quantify its sensitivity to gravity gradients using frequency-space analysis. We will consider objects near Earth-based experiments and space debris in proximity of satellites and estimate the minimum detectable mass of the object as a function of their distance, velocity, and orientation
