The Impact of Acute Psychosocial Stress on Magnetoencephalographic Correlates of Emotional Attention and Exogenous Visual Attention

Stress-induced acute activation of the cerebral catecholaminergic systems has often been found in rodents. However, little is known regarding the consequences of this activation on higher cognitive functions in humans. Theoretical inferences would suggest increased distractibility in the sense of increased exogenous attention and emotional attention. The present study investigated the influence of acute stress responses on magnetoencephalographic (MEG) correlates of visual attention. Healthy male subjects were presented emotional and neutral pictures in three subsequent MEG recording sessions after being exposed to a TSST-like social stressor, intended to trigger a HPA-response. The subjects anticipation of another follow-up stressor was designed to sustain the short-lived central catecholaminergic stress reactions throughout the ongoing MEG recordings. The heart rate indicates a stable level of anticipatory stress during this time span, subsequent cortisol concentrations and self-report measures of stress were increased. With regard to the MEG correlates of attentional functions, we found that the N1m amplitude remained constantly elevated during stressor anticipation. The magnetic early posterior negativity (EPNm) was present but, surprisingly, was not at all modulated during stressor anticipation. This suggests that a general increase of the influence of exogenous attention but no specific effect regarding emotional attention in this time interval. Regarding the time course of the effects, an influence of the HPA on these MEG correlates of attention seems less likely. An influence of cerebral catecholaminergic systems is plausible, but not definite

The preparatory Set: A Novel Approach to Understanding Stress, Trauma, and the Bodymind Therapies

Basic to all motile life is a differential approach/avoid response to perceived features of environment. The stages of response are initial reflexive noticing and orienting to the stimulus, preparation, and execution of response. Preparation involves a coordination of many aspects of the organism: muscle tone, posture, breathing, autonomic functions, motivational/emotional state, attentional orientation, and expectations. The organism organizes itself in relation to the challenge. We propose to call this the preparatory set (PS). We suggest that the concept of the PS can offer a more nuanced and flexible perspective on the stress response than do current theories. We also hypothesize that the mechanisms of body-mind therapeutic and educational systems (BTES) can be understood through the PS framework. We suggest that the BTES, including meditative movement, meditation, somatic education, and the body-oriented psychotherapies, are approaches that use interventions on the PS to remedy stress and trauma. We discuss how the PS can be adaptive or maladaptive, how BTES interventions may restore adaptive PS, and how these concepts offer a broader and more flexible view of the phenomena of stress and trauma. We offer supportive evidence for our hypotheses, and suggest directions for future research. We believe that the PS framework will point to ways of improving the management of stress and trauma, and that it will suggest directions of research into the mechanisms of action of BTES

Punishment-related memory-guided attention: Neural dynamics of perceptual modulation

Remembering the outcomes of past experiences allows us to generate future expectations and shape selection in the long-term. A growing number of studies has shown that learned positive reward values impact spatial memory-based attentional biases on perception. However, whether memory-driven attentional biases extend to punishment-related values has received comparatively less attention. Here, we manipulated whether recent spatial contextual memories became associated with successful avoidance of punishment (potential monetary loss). Behavioural and electrophysiological measures were collected from 27 participants during a subsequent memory-based attention task, in which we tested for the effect of punishment avoidance associations. Punishment avoidance significantly amplified effects of spatial contextual memories on visual search processes within natural scenes. Compared to non-associated scenes, contextual memories paired with punishment avoidance lead to faster responses to targets presented at remembered locations. Event-related potentials elicited by target stimuli revealed that acquired motivational value of specific spatial locations, by virtue of their association with past avoidance of punishment, dynamically affected neural signatures of early visual processing (indexed by larger P1 and earlier N1 potentials) and target selection (as indicated by reduced N2pc potentials). The present results extend our understanding of how memory, attention, and punishment-related mechanisms interact to optimize perceptual decision in real world environmentsThis research was supported by a Project Grant to S.D. from the Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia, Spain (EM2012/017). S.S-S was supported by a grant for predoctoral contracts from the Spanish Ministry of Economy and Competitiveness, Spain (BES-2016-076298). A.C.N. is supported by Wellcome Trust Senior Investigator Award, United Kingdom (104571/Z/14/Z)S

Social Anxiety: Understanding the Attentional Bias to Threat

Biased attention toward threatening facial expressions is an important maintaining and possibly aetiological factor for social anxiety. However, little is known about the underlying mechanisms. To develop our understanding of this threat bias, the relative contributions of top-down attention, bottom-up attention, and selection history were differentiated across four studies. In Study One, the roles of top-down attention, bottom-up attention, and selection history were tested in an unselected sample using a modification of the dot-probe task, in which participants were cued to attend to a happy or angry face on each trial. Results showed that attentional orienting toward facial expressions was not exclusively driven by bottom-up attentional capture as some previous theories suggest; but instead, participants could shift attention toward emotional faces in a top-down manner. This effect was eliminated when the faces were inverted, demonstrating that top-down attention relies on holistic face processing. Study One found no evidence of selection history (i.e., no improvement on repeated trials or blocks of trials in which the task was to orient to the same expression). Study Two tested whether this ability to use top-down attention to orient to emotional faces is impaired for individuals with social anxiety. Using the same task as Study One, Study Two found that participants with higher levels of social anxiety were selectively impaired in attentional shifting toward a cued happy face when it was paired with an angry face, but not when paired with a neutral face. These results indicate that high social anxiety is associated with deficits in top-down control of attention, which are selectively revealed in the presence of non-task-relevant threat. The results of Study Two could be explained by bottom-up attention to threat or a top-down set for threat that could not be overcome by the instruction to attend to a happy face. To test this, Study Three utilised a modified dot-probe task in which participants were presented with an upright face paired with an inverted face (displaying a disgust or neutral expression) and engagement with and disengagement of attention from threatening faces were measured separately. The task was performed under no, low, and high working-memory load conditions. Since working-memory load draws on the same resources as top-down attention, interference from increasing working-memory load on attentional orienting would point to a role for top-down attention. Social anxiety was not associated with delayed disengagement from threat. However, surprisingly, high social anxiety was associated with an engagement bias away from threat, while low social anxiety was associated with a bias toward threat. These results were unaffected by the working-memory load manipulation. However, some methodological issues were identified with the study. Study Four overcame these methodological issues by using a paired angry and neutral face under no, low and high working-memory load conditions. Higher levels of social anxiety were associated with increased engagement with threat under no-load, but not under low- and high-load conditions. Thus, this body of research provides evidence that social anxiety is associated with an engagement bias to threat, which is driven by top-down attention

Enkinaesthetic polyphony: the underpinning for first-order languaging

We contest two claims: (1) that language, understood as the processing of abstract symbolic forms, is an instrument of cognition and rational thought, and (2) that conventional notions of turn-taking, exchange structure, and move analysis, are satisfactory as a basis for theorizing communication between living, feeling agents. We offer an enkinaesthetic theory describing the reciprocal affective neuro-muscular dynamical flows and tensions of co- agential dialogical sense-making relations. This “enkinaesthetic dialogue” is characterised by a preconceptual experientially recursive temporal dynamics forming the deep extended melodies of relationships in time. An understanding of how those relationships work, when we understand and are ourselves understood, when communication falters and conflict arises, will depend on a grasp of our enkinaesthetic intersubjectivity

Neural alpha oscillations index the balance between self-other integration and segregation in real-time joint action

Shared knowledge and interpersonal coordination are prerequisites for most forms of social behavior. Influential approaches to joint action have conceptualized these capacities in relation to the separate constructs of co-representation (knowledge) and self-other entrainment (coordination). Here we investigated how brain mechanisms involved in co-representation and entrainment interact to support joint action. To do so, we used a musical joint action paradigm to show that the neural mechanisms underlying co-representation and self-other entrainment are linked via a process – indexed by EEG alpha oscillations – regulating the balance between self-other integration and segregation in real time. Pairs of pianists performed short musical items while action familiarity and interpersonal (behavioral) synchronization accuracy were manipulated in a factorial design. Action familiarity referred to whether or not pianists had rehearsed the musical material performed by the other beforehand. Interpersonal synchronization was manipulated via congruent or incongruent tempo change instructions that biased performance timing towards the impending, new tempo. It was observed that, when pianists were familiar with each other's parts, millisecond variations in interpersonal synchronized behavior were associated with a modulation of alpha power over right centro-parietal scalp regions. Specifically, high behavioral entrainment was associated with self-other integration, as indexed by alpha suppression. Conversely, low behavioral entrainment encouraged reliance on internal knowledge and thus led to self-other segregation, indexed by alpha enhancement. These findings suggest that alpha oscillations index the processing of information about self and other depending on the compatibility of internal knowledge and external (environmental) events at finely resolved timescales

The preparatory Set: A Novel Approach to Understanding Stress, Trauma, and the Bodymind Therapies

Basic to all motile life is a differential approach/avoid response to perceived features of environment. The stages of response are initial reflexive noticing and orienting to the stimulus, preparation, and execution of response. Preparation involves a coordination of many aspects of the organism: muscle tone, posture, breathing, autonomic functions, motivational/emotional state, attentional orientation, and expectations. The organism organizes itself in relation to the challenge. We propose to call this the preparatory set (PS). We suggest that the concept of the PS can offer a more nuanced and flexible perspective on the stress response than do current theories. We also hypothesize that the mechanisms of body-mind therapeutic and educational systems (BTES) can be understood through the PS framework. We suggest that the BTES, including meditative movement, meditation, somatic education, and the body-oriented psychotherapies, are approaches that use interventions on the PS to remedy stress and trauma. We discuss how the PS can be adaptive or maladaptive, how BTES interventions may restore adaptive PS, and how these concepts offer a broader and more flexible view of the phenomena of stress and trauma. We offer supportive evidence for our hypotheses, and suggest directions for future research. We believe that the PS framework will point to ways of improving the management of stress and trauma, and that it will suggest directions of research into the mechanisms of action of BTES

The neurophysiology of intersensory selective attention and task switching

Our ability to selectively attend to certain aspects of the world and ignore others is fundamental to our day-to-day lives. The need for selective attention stems from capacity limitations inherent in our perceptual and cognitive processing architecture. Because not every elemental piece of our environment can be fully processed in parallel, the nervous system must prioritize processing. This prioritization is generally referred to as selective attention. Meanwhile, we are faced with a world that is constantly in flux, such that we have to frequently shift our attention from one piece of the environment to another and from one task to another. This process is generally referred to as task-switching. Neural oscillations in the alpha band (~8-14 Hz) have been shown to index the distribution of selective attention, and there is increasing evidence that oscillations in this band are in fact utilized by the nervous system to suppress distracting, task-irrelevant information. In order to elaborate on what is known of the function of alpha oscillations as well as current models of both intersensory selective attention and task switching, I investigated the dynamics of alpha amplitude modulations within the context of intersenory selective attention and task switching in neurologically typical young adults. Participants were alternately cued to attend to either the visual or auditory aspect of a compound audio-visual stimulus while high-density electroencephalography was recorded. It is typically found that alpha power increases over parieto-occipital cortices when attention is directed away from the visual modality and to the auditory modality. I report evidence that alpha oscillations play a role in task-switching (e.g., when switching from attending the visual task versus repeating this task), specifically as biasing signals, that may operate to re-weight competition among two tasks-sets. I further investigated the development of these same processes in school-aged children and adolescents. While exhibiting typical patterns of alpha modulations relevant to selective attention, Young school-aged children (8-12 years), compared to older participants, did not demonstrate specific task switching modulation of alpha oscillations, suggesting that this process does not fully develop until late adolescence. Finally, children and adolescents on the autism spectrum failed altogether to exhibit differentiation of alpha power between attend-visual and attend-auditory conditions--an effect present in age and IQ matched controls--suggesting that ASD individuals may have a deficit in the overall top-down deployment of alpha oscillatory biasing signals. This could result in an inability to ignore distracting information in the environment, leading to an overwhelming, disordered experience of the world, resulting in profound effects on the both social interaction and cognitive development. Altogether, these findings add to growing evidence that alpha oscillations serve as domain general biasing signals and are integral to our flexible goal-oriented behavior. Furthermore, the flexible use of these biasing signals in selective attention and task switching develops over a protracted period, and appears to be aberrant in autism spectrum disorder