Vertex-Based Analysis of Cerebral Blood Flow and Fractional Amplitude of Low-Frequency Fluctuations (CBF-fALFF) Coupling in Moderate-to-Severe Traumatic Brain Injury During the First Year Post-Injury

Traumatic brain injury (TBI) is known to involve damage in the neurovascular unit. TBI may disrupt the brain’s neurovascular coupling–the relationship between cerebral blood flow and neural activity–that can lead to cognitive and functional impairments. This study attempted to non-invasively investigate neurovascular coupling in patients with moderate to severe TBI (msTBI) during the first year post-injury using a combined metric of cerebral blood flow (CBF) and fractional amplitude of low-frequency fluctuations (fALFF), a proxy for spontaneous neural activity. Using arterial spin labeling (ASL) and functional MRI sequences, CBF and fALFF were measured in 29 msTBI patients 3-, 6- and 12-months post-injury for within-group longitudinal comparisons. Thirty-four demographically matched healthy controls were assessed once for between-group comparisons. A vertex-based preprocessing pipeline was used to map spatial patterns of CBF-fALFF coupling across the cortical surface. Across-vertex global coupling was estimated by association (measured by regression or correlation coefficients) between CBF and fALFF values across the whole hemisphere. In addition, vertex-wise regional coupling values were calculated using locally weighted regression between fALFF and CBF. The coupling calculated on a global level revealed significant group differences between controls and TBI patients, indicating potential neurovascular coupling dysfunction in chronic msTBI patients. At 6 months post-injury, the duration of post-traumatic amnesia was significantly correlated with global coupling values based on regression coefficients. In contrast, after correcting for multiple comparisons, the vertex-wise regional group comparison showed no significant differences in CBF-fALFF coupling between msTBI patients and controls. Neither globally nor locally defined coupling metrics showed significant longitudinal changes or relationships with neuropsychological variables within the patient group. Potential explanations underlying the absence of longitudinal differences and the dissociation between the global and local coupling findings were discussed

À la poursuite de Céline à New York

Louis-Ferdinand Céline n’a cessé de multiplier les allers-retours entre Paris et New York, jusqu’à la veille de la Seconde Guerre mondiale. Le voyage commence dès 1925. Sa première expérience avec la Société des Nations (ancêtre de l’ONU), en tant que “responsable des échanges de médecins spécialistes”, prouve également son bon niveau en anglais. C\u27est sous l\u27égide de l’organisation internationale que le Docteur Louis Destouches se voit confier la direction d\u27une délégation de médecins sud-américains, qui l\u27amène à traverser toute l\u27Amérique de Nord. Ce périple de quatre mois le conduit de Cuba à la Louisiane, de New York à Montréal, esquissant déjà la trajectoire de l’odyssée célinienne. Après la publication de son roman phare, Voyage au bout de la nuit (1932), l\u27auteur revient à trois reprises sur le continent nord-américain. Une destination qui va étrangement se resserrer autour de New York, à partir de 1937. Sous la couverture officielle d’un écrivain talentueux, notre étude permet de mieux comprendre quelles furent ses intentions réelles. Au fil du temps, ses voyages promotionnels vont se muer en voyages politiques, où partout sur son passage se croisent les chefs de fil de mouvements nationalistes. Cet itinéraire met en lumière l’ambition et la sincérité de son engagement dans l’idéologie du IIIème Reich. Notre enquête explore les convictions profondes de l’écrivain, qui vont le conduire à organiser une partie de la propagande nazie à l’échelle internationale, notamment à travers la publication et la diffusion de pamphlets à partir de 1937. Louis-Ferdinand Céline continued to travel back and forth between Paris and New York until the eve of the Second World War. The journey began in 1925. His first experience with the League of Nations (the forerunner of the UN), as “responsible for the exchange of specialist doctors”, also proved his good level of English. It was under the aegis of the international organization that Doctor Louis Destouches was entrusted with the leadership of a delegation of South American doctors, which led him to cross the whole of North America. This four-month journey took him from Cuba to Louisiana, from New York to Montreal, already outlining the trajectory of Céline’s odyssey. After the publication of his flagship novel, Journey to the End of the Night (1932), the author returned to the North American continent three times. A destination that would strangely narrow around New York, from 1937. Under the official cover of a talented writer, our study allows us to better understand what his real intentions were. Over time, his promotional trips would turn into political trips, where everywhere he went, the leaders of nationalist movements would cross paths. This itinerary highlights the ambition and sincerity of his commitment to the ideology of the Third Reich. Our investigation explores the writer\u27s deep convictions, which would lead him to organize part of the Nazi propaganda on an international scale, notably through the publication and distribution of pamphlets from 1937

Activism within the Music and Recorded Sound Archive

This thesis explores the integration of applied ethnomusicology within the recorded sound archive of the New York Public Library. The process of repatriating recorded sound through community engagement lead to the development and eventual reparative work of outdated subject headings and other descriptive language within the archive. This thesis also explores how cultural preservation of similar non-physical fields such as naming conventions within linguistics and the development of gastronationalism combats globalization and ultimately colonization

Elementary Italian II

Italian II aims at increasing the student\u27s ability to use basic forms of oral communication in Italian through constant use of the everyday idiom. Carefully graded practice in reading and writing supplement the conversational aspects of the course. We will cover the second half of Italian Espresso 1 that is, chapter 7 through chapter 11, and the accompanying chapters in the workbook. We also will work on vocabulary, grammar, pronunciation, oral comprehension, conversation, spelling and writing. Speaking, oral comprehension, and conversation will beemphasized

How early pedagogical experiences relate to teachers’ career motivations

Early pedagogical experiences are known to influence teaching career choice, yet research on their relations with motivational beliefs remains limited. Applying the FIT-Choice model, we investigated how the amount and type of early pedagogical experiences relate to career motivations in a diverse, urban sample of teacher education students (N = 901). ANOVAs and multigroup path analyses revealed smaller effects of socialization on motivational beliefs and larger effects of intrinsic value on career choice satisfaction and planned persistence for participants with lead teaching experience. Findings illuminate how types of teaching experience are differentially associated with career motivations among teacher trainees

Spirometry: For the Winds in Us

Spirometers are devices used to measure lung capacity. This capstone is a creative study of what restores our breathing aptitude as a response to the suffocating and alienating consequences of whiteness for people racialized as white. The project is a sequence of lyric essays. The first lyric essay frames whiteness as a condition of exile and examines the cultural and emotional currents that shore it up. I use exile as a frame to emphasize the intensity of the spiritual and cultural alienation that people racialized as white experience. I also contextualize the dis-ease of suicide in my own lineage, and in white men broadly, as a natural consequence of the process of racialization. Suffocation–literally and in the sense of being emotionally stifled–is one of exile’s most pernicious consequences. The remaining essays attend to what makes way for breath amidst this abiding unease. They are gestures to welcome breath back that I call ‘panes.’ A root meaning of the word window is “breath door.” Panes here are thresholds to unencumbered respiration. As I catch my breath, or let it catch me, I notice more deeply the choices that are available to interrupt misery and cycles of violence, to move toward lively responsibility for myself, my histories, this earth and the people around me. The panes tell of my longing to relinquish whiteness and of some ideas toward this renunciation on the planes of language and life

shapes that hide their shadows

shapes that hide their shadows concerns itself with the mutability of memory. The complexities of girlhood to womanhood, and the way we are shaped by place and space, are explored through the artist recounting childhood memories connected to her grandparents\u27 hometowns. Divided into three different sections, the artist discusses drawing as medium, creating a lexicon through using visual symbols, and the logistics of building your own archive

Race and Ethnicity

Race and Ethnicity while often used inter-changeably, are two distinct construct. The Lecture explores the differences as well as the inter-relatedness of these constructs, as well as how different ethnic groups are received by society, with a focus on here in the United States