Reflections on two decades of research on sorghum based farming systems in Northern Nigeria and Botswana

A conference paper on research on sorghum based farming systems in Botswana and Northern Nigeria.The paper begins by comparing farming circumstances and sorghum production systems in northern Nigeria and Botswana. The comparison provides a background for characterising farmers’ food security strategies. This is followed by a brief review of changes in research approaches that have occurred over the last 20 years in both countries. We propose that there is much complementarity between micro-level farming systems work and macro policy analysis in efforts to attain improved food security. On the basis of this perspective, we discuss in the fourth section some issues affecting the efficiency of future micro-level food security research.The research supporting the preparation the proceedings papers was financed by the U.S. Agency for International Development, Bureau of Science and Technology; Bureau for Africa; and the Southern Africa Regional Programme

Antiferromagnetic Domains and Superconductivity in UPt3

We explore the response of an unconventional superconductor to spatially inhomogeneous antiferromagnetism (SIAFM). Symmetry allows the superconducting order parameter in the E-representation models for UPt3 to couple directly to the AFM order parameter. The Ginzburg-Landau equations for coupled superconductivity and SIAFM are solved numerically for two possible SIAFM configurations: (I) abutting antiferromagnetic domains of uniform size, and (II) quenched random disorder of `nanodomains' in a uniform AFM background. We discuss the contributions to the free energy, specific heat, and order parameter for these models. Neither model provides a satisfactory account of experiment, but results from the two models differ significantly. Our results demonstrate that the response of an E_{2u} superconductor to SIAFM is strongly dependent on the spatial dependence of AFM order; no conclusion can be drawn regarding the compatibility of E_{2u} superconductivity with UPt3 that is independent of assumptions on the spatial dependence of AFMComment: 12 pages, 13 figures, to appear in Phys. Rev.

Peasant farmer behavior and cereal technologies: stochastic programming analysis in Niger

Peasant farmers in Sahelian West Africa adjust to rainfall uncertainties in the agricultural season by making decisions sequentially as a function of the evolving rainfall patterns. Understanding such flexibilities in farmer decision-making is central to technology introduction. This paper determines how sequential decision making under weather uncertainty affects the adoption and farm-level effects of cereal technologies in Niger. The study also draws policy implications for a price floor to arrest the substantial fall in cereal prices in good rainfall years when farmers have more grains to sell. The methodology used is discrete stochastic programming. The paper shows that the ability of peasant farmers to adapt cropping and resource management strategies to the rainfall patterns is the basis for their survival in this high-risk environment. Model results show that by (a) carrying a portfolio mix of varieties of varying maturities, and (b) making sequential decisions based upon rainfall expectations, farmers can adapt to the production uncertainties. Breeding programmes should therefore be diversified to develop not only early-maturing cultivars, but also improved intermediate and long-season varietie

Doping-insensitive density-of-states suppression in polycrystalline iron-based superconductor SmO1−x_{1-x}Fx_{x}FeAs

We investigated the temperature dependence of the density-of-states in the iron-based superconductor SmO_1-xF_xFeAs (x=0, 0.12, 0.15, 0.2) with high resolution angle-integrated photoemission spectroscopy. The density-of-states suppression is observed with decreasing temperature in all samples, revealing two characteristic energy scales (10meV and 80meV). However, no obvious doping dependence is observed. We argue that the 10meV suppression is due to an anomalously doping-independent normal state pseudogap, which becomes the superconducting gap once in the superconducting state; and alert the possibility that the 80meV-scale suppression might be an artifact of the polycrystalline samples.Comment: 4 pages, 4 figure

Formation of dense partonic matter in relativistic nucleus-nucleus collisions at RHIC: Experimental evaluation by the PHENIX collaboration

Extensive experimental data from high-energy nucleus-nucleus collisions were recorded using the PHENIX detector at the Relativistic Heavy Ion Collider (RHIC). The comprehensive set of measurements from the first three years of RHIC operation includes charged particle multiplicities, transverse energy, yield ratios and spectra of identified hadrons in a wide range of transverse momenta (p_T), elliptic flow, two-particle correlations, non-statistical fluctuations, and suppression of particle production at high p_T. The results are examined with an emphasis on implications for the formation of a new state of dense matter. We find that the state of matter created at RHIC cannot be described in terms of ordinary color neutral hadrons.Comment: 510 authors, 127 pages text, 56 figures, 1 tables, LaTeX. Submitted to Nuclear Physics A as a regular article; v3 has minor changes in response to referee comments. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.htm

Absence of serological rheumatoid arthritis biomarkers in inflammatory bowel disease patients with arthropathies

Transplantation and autoimmunit

Functional Characterization of N297A, A Murine Surrogate for low-Fc Binding Anti-Human CD3 Antibodies

Several low- or non-FcR binding anti-human CD3 monoclonal antibodies have been under investigation for the treatment of autoimmune diseases. To model the mechanism of action of these anti-human CD3 mAbs in the murine system, an Fc-modified anti-mouse CD3 antibody (N297A) was generated. N297A exhibited similar biological effects as Fc-modified anti-human CD3 antibodies including rapid, reversible reduction in peripheral leukocyte numbers, differential modulation of activated versus resting T cells, and reduced levels of induced cytokine release compared to the non-Fc-modified parent antibody. In an in vivo model of colitis induced by adoptive transfer of IL–10-deficient cells, administration of N297A significantly reduced body weight loss. As N297A shared many functional characteristics of non-FcR binding anti-human CD3 mAbs both in vitro and in vivo, it provides a means to model the mechanisms of action of Fc-modified anti-human CD3 antibodies in mouse