76 research outputs found
Entwicklung von Gallengangskarzinomen nach operativer Versorgung von Choledochuszysten:Fallbericht mit Literaturstudium
Choledochuszysten sind eine seltene Erkrankung, die u.a. die Bildung von Gallenwegskarzinomen begünstigen. Aus diesem Grund bedürfen sie rechtzeitig einer chirurgischen Versorgung. In den jüngsten Jahren mehrten sich allerdings Berichte von Gallenwegskarzinomen, die sich nach operativer Versorgung von Choledochuszysten entwickelt haben. Ausgehend von einem eigenen Fallbericht wurden die in der Literatur publizierten Fälle hinsichtlich Klinik, Epidemiologie, Ätiologie und Therapie analysiert und Empfehlungen für die Praxis zusammengefasst
Understanding the fate of nitrogen during catalytic hydrothermal liquefaction of sewage sludge
In this study, the fate of nitrogen during catalytic hydrothermal liquefaction (HTL) of sewage sludge (SS) is investigated using three different catalysts (CuNi/SiO, HCOOH, CuSO) with 5 wt% loading. The bio-crude yields obtained from HTL experiments catalyzed with CuNi/SiO are similar to those obtained through non-catalyzed experiments. HCOOH slightly increases the bio-crude yields, while maximum yields of 24.5 wt% is obtained in the presence of CuSO, which also reduces the nitrogen content by 15 % and enhances the hydrocarbons compared to the non-catalyzed HTL. Mechanistic investigations regarding the interaction of amino acids and carbohydrates by Maillard reactions are carried out using model compounds, namely lysine and lactose. CuSO effectively increases the yield with 50 % and reduces the nitrogen content by 24 % in the bio-crude during HTL of lysine alone. In the case of the model mixtures, bio-crude yields, nitrogen content, and Maillard reactions products behaved similarly both for catalytic and non-catalytic HTL, a slight reduction of amines was found in the presence of CuSO. Hydro-char and some organic compounds are assumed to act highly reductant during catalytic HTL. Coke deposition and adsorbed poisoning by Maillard reaction products are proposed as the main reasons for the deactivation of catalysts
2010 – Innenansichten der SLUB: Ein Kalenderprojekt
Auf der Suche nach kreativen Ideen für ein Kalenderlayout, mit dem unverkennbar die SLUB assoziiert wird, hat die SLUB im September 2008 eine Kooperation mit der Akademie für Informations- und Kommunikations-Design (AIK) vereinbart. Im Rahmen eines an der AIK als Abschlussarbeit im Schuljahr 2008/2009 durchgeführten Kompetenzprojektes, dem „Gesellenstück“ zum Nachweis der beruflichen Kompetenz, setzten sich drei angehende gestaltungstechnische Assistentinnen der Fachrichtung Grafik mit der Thematik auseinander und legten abschließend drei von der Herangehensweise sehr differenzierte Kalenderlayouts vor
SoFiA: a flexible source finder for 3D spectral line data
We introduce SoFiA, a flexible software application for the detection and
parameterization of sources in 3D spectral-line datasets. SoFiA combines for
the first time in a single piece of software a set of new source-finding and
parameterization algorithms developed on the way to future HI surveys with
ASKAP (WALLABY, DINGO) and APERTIF. It is designed to enable the general use of
these new algorithms by the community on a broad range of datasets. The key
advantages of SoFiA are the ability to: search for line emission on multiple
scales to detect 3D sources in a complete and reliable way, taking into account
noise level variations and the presence of artefacts in a data cube; estimate
the reliability of individual detections; look for signal in arbitrarily large
data cubes using a catalogue of 3D coordinates as a prior; provide a wide range
of source parameters and output products which facilitate further analysis by
the user. We highlight the modularity of SoFiA, which makes it a flexible
package allowing users to select and apply only the algorithms useful for their
data and science questions. This modularity makes it also possible to easily
expand SoFiA in order to include additional methods as they become available.
The full SoFiA distribution, including a dedicated graphical user interface, is
publicly available for download.Comment: MNRAS, accepted. SoFiA is registered at the Astrophysics Source Code
Library with ID ascl:1412.001. Download SoFiA at
https://github.com/SoFiA-Admin/SoFi
Predictions for ASKAP Neutral Hydrogen Surveys
The Australian Square Kilometer Array Pathfinder (ASKAP) will revolutionise
our knowledge of gas-rich galaxies in the Universe. Here we present predictions
for two proposed extragalactic ASKAP neutral hydrogen (HI) emission-line
surveys, based on semi-analytic models applied to cosmological N-body
simulations. The ASKAP HI All-Sky Survey, known as WALLABY, is a shallow 3 Pi
survey (z = 0 - 0.26) which will probe the mass and dynamics of over 600,000
galaxies. A much deeper small-area HI survey, called DINGO, aims to trace the
evolution of HI from z = 0 - 0.43, a cosmological volume of 40 million Mpc^3,
detecting potentially 100,000 galaxies. The high-sensitivity 30 antenna ASKAP
core (diameter ~2 km) will provide an angular resolution of 30 arcsec (at z=0).
Our simulations show that the majority of galaxies detected in WALLABY (87.5%)
will be resolved. About 5000 galaxies will be well resolved, i.e. more than
five beams (2.5 arcmin) across the major axis, enabling kinematic studies of
their gaseous disks. This number would rise to 160,000 galaxies if all 36 ASKAP
antennas could be used; the additional six antennas provide baselines up to 6
km, resulting in an angular resolution of 10 arcsec. For DINGO this increased
resolution is highly desirable to minimise source confusion; reducing confusion
rates from a maximum of 10% of sources at the survey edge to 3%. We estimate
that the sources detected by WALLABY and DINGO will span four orders of
magnitude in total halo mass (from 10^{11} to 10^{15} Msol) and nearly seven
orders of magnitude in stellar mass (from 10^{5} to 10^{12} Msol), allowing us
to investigate the process of galaxy formation across the last four billion
years.Comment: 21 pages, accepted for publication in MNRAS, minor updates to
published version and fixed links. Movies and images available at
http://ict.icrar.org/store/Movies/Duffy12c
The genome of the protozoan parasite Cystoisospora suis and a reverse vaccinology approach to identify vaccine candidates
Vaccine development targeting protozoan parasites remains challenging, partly due to the complex interactions between these eukaryotes and the host immune system. Reverse vaccinology is a promising approach for direct screening of genome sequence assemblies for new vaccine candidate proteins. Here, we applied this paradigm to Cystoisospora suis, an apicomplexan parasite that causes enteritis and diarrhea in suckling piglets and economic losses in pig production worldwide. Using Next Generation Sequencing we produced an ∼84 Mb sequence assembly for the C. suis genome, making it the first available reference for the genus Cystoisospora. Then, we derived a manually curated annotation of more than 11,000 protein-coding genes and applied the tool Vacceed to identify 1,168 vaccine candidates by screening the predicted C. suis proteome. To refine the set of candidates, we looked at proteins that are highly expressed in merozoites and specific to apicomplexans. The stringent set of candidates included 220 proteins, among which were 152 proteins with unknown function, 17 surface antigens of the SAG and SRS gene families, 12 proteins of the apicomplexan-specific secretory organelles including AMA1, MIC6, MIC13, ROP6, ROP12, ROP27, ROP32 and three proteins related to cell adhesion. Finally, we demonstrated in vitro the immunogenic potential of a C. suis-specific 42 kDa transmembrane protein, which might constitute an attractive candidate for further testing
Neutral Hydrogen Gas in Interacting Galaxies: The NGC 1511 galaxy group
We present HI line and 20-cm radio continuum observations of the NGC 1511
galaxy group obtained with the Australia Telescope Compact Array. The data
reveal an extended, rather disturbed HI distribution for the peculiar starburst
galaxy NGC 1511 and a narrow bridge to its small companion galaxy, NGC 1511B,
which has been severely distorted by the interaction/collision between the two
galaxies. No stellar counterpart to the gaseous bridge has been detected. In
addition, we find that the peculiar optical ridge to the east of NGC 1511 is
probably the stellar remnant of a galaxy completed disrupted by interactions
with NGC 1511. The slightly more distant neighbour, NGC 1511A, shows a regular
HI velocity field and no obvious signs of interactions. Radio continuum
emission from NGC 1511 reveals three prominent sources on top of a more
diffuse, extended distribution. We derive an overall star formation rate of 7
Msun/yr. The most enhanced star formation is found in the south-eastern part of
the disk, coincident with several bright HII regions, and closest to the
peculiar optical ridge. No continuum emission was detected in the companions,
but NGC 1511B appears to show an HII region at its faint western edge, closest
to NGC 1511. The group displays a prime example of interaction-induced star
formation activity.Comment: 9 pages, 8 figures, accepted for publication in MNRA
Deep Investigation of Neutral Gas Origins (DINGO): HI stacking experiments with early science data
We present early science results from Deep Investigation of Neutral Gas
Origins (DINGO), an HI survey using the Australian Square Kilometre Array
Pathfinder (ASKAP). Using ASKAP sub-arrays available during its commissioning
phase, DINGO early science data were taken over 60 deg of the
Galaxy And Mass Assembly (GAMA) 23 h region with 35.5 hr integration time. We
make direct detections of six known and one new sources at . Using HI
spectral stacking, we investigate the HI gas content of galaxies at for different galaxy colours. The results show that galaxy morphology
based on optical colour is strongly linked to HI gas properties. To examine
environmental impacts on the HI gas content of galaxies, three sub-samples are
made based on the GAMA group catalogue. The average HI mass of group central
galaxies is larger than those of satellite and isolated galaxies, but with a
lower HI gas fraction. We derive a variety of HI scaling relations for physical
properties of our sample, including stellar mass, stellar mass surface density,
colour, specific star formation rate, and halo mass. We find that the
derived HI scaling relations are comparable to other published results, with
consistent trends also observed to 0.5 dex lower limits in stellar mass
and stellar surface density. The cosmic HI densities derived from our data are
consistent with other published values at similar redshifts. DINGO early
science highlights the power of HI spectral stacking techniques with ASKAP.Comment: 27 pages, 25 figures, 10 tables, accepted for publication in MNRA
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