116 research outputs found
Transcriar a linguagem rosiana para o francĂȘs no conto A hora e a vez de Augusto Matraga
Trabalho de conclusĂŁo de curso (graduação)âUniversidade de BrasĂlia, Instituto de Letras, Departamento de LĂnguas Estrangeiras e Tradução, Curso de Letras â Tradução â FrancĂȘs, 2016.âA hora e a vez de Augusto Matragaâ Ă© um conto escrito por JoĂŁo GuimarĂŁes Rosa e publicado em Sagarana em 1946. O objetivo desse trabalho Ă©, a partir de nossa tradução para o francĂȘs, discutir o processo tradutĂłrio e a necessidade de uma transcriação frente a um texto criativo. JoĂŁo GuimarĂŁes Rosa vĂȘ a linguagem como um meio de transformar o mundo e defende a necessidade de renovĂĄ-la para que conserve sua força. Ele faz, portanto, um uso singular da lĂngua portuguesa, fora das normas da lĂngua padrĂŁo. âA hora e a vez de Augusto Matragaâ comporta assim inĂșmeras inovaçÔes de linguagem, tanto no nĂvel lexical que gramĂĄtico-sintĂĄtico, que devem ser transpostas para outra lĂngua. As teorias apresentadas por Walter Benjamin em âA tarefa do tradutorâ e por Haroldo de Campos em Transcriaçãopermitem encontrar um caminho para chegar uma tradução satisfatĂłria. Assim, o trabalho do tradutor consiste em analisar os processos de escrita a fim de poder recri-alos em francĂȘs.âA hora e a vez de Augusto Matragaâ est un conte Ă©crit par JoĂŁo GuimarĂŁes Rosa et publiĂ© dans Sagaranaen 1946. Lâobjectif de ce travail est de, Ă partir de notre traduction vers le français, discuter le processus de traduction et la necessite dâune transcriation face Ă un texte criatif. JoĂŁo GuimarĂŁes Rosa voit le langage comme um moyen de transformer le monde et dĂ©fend la necessite de le renouveler pour quâil conserve sa force. Il fait donc un usage singulier de la langue portugaise, en dehors des normes du langage Ă©crit. âA hora e a vez de Augusto Matragaâ comporte ainsi de nombreuses innovations de langage, tant au niveau lexical que grammatico-syntaxique, qui doivent ĂȘtre transposĂ©es vers une autre langue.Les thĂ©ories prĂ©sentĂ©es par Walter Benjamin dans âLa tĂąche du traducteurâ et par Haroldo de Campos dans Transcriação permettent de trouver un chemin pour arriver Ă une traduction satisfaisante. Ainsi, le travail du traducteur consiste Ă analyser les processus dâĂ©criture de lâauteur afin de pouvoir les recrĂ©er en français
Central activation after chronic vagus nerve stimulation in pigs : contribution of functional imaging
Chronic vagus nerve stimulation (VNS), used to treat refractory epilepsy, has the potential to alter
food intake in animals and humans. The aim of our study was to evaluate the impact of VNS on the
feeding behaviour of pigs used as a human model, and to investigate the origin of its potential effects.
Food intake was significantly decreased after five weeks of chronic VNS. This reduction was not due
to stimulation of the vagus efferents as neither gastric compliance nor gastric emptying was altered.
VNS triggered a reorganisation of brain activation, probably via subcortical structures involved in the
reward mechanism. The activation of the olfactory bulb during VNS is probably one of the mechanisms
responsible for the drastic changes in food preference in favour of lipids.La stimulation vagale
chronique (VNS), une thérapeutique de l'épilepsie pharmacorésistante, serait capable chez
l'animal et chez l'homme de modifier le comportement alimentaire. Le but de notre Ă©tude
était de préciser l'impact de la VNS sur le comportement alimentaire du porc pris comme
modĂšle de l'homme et d'Ă©tudier l'origine de ses effets potentiels. La VNS conduit au bout de
cinq semaines à une réduction de la quantité d'aliment ingéré. Cette réduction n'est pas la
conséquence de la stimulation des efférences vagales, la compliance ou l'évacuation de
l'estomac, n'étant pas modifiée. Par contre, la VNS provoque une réorganisation de
l'activation cérébrale mettant vraisemblablement en jeu les structures sous-corticales
impliquées dans le processus de récompense. L'activation du bulbe olfactif au cours de la
VNS est probablement l'un des éléments à l'origine des modifications drastiques des
préférences alimentaires en faveur des lipides
ABOUT INDIGENOUS POETRY
Este artigo nasce a partir de possĂveis interpretaçÔes do poema âAy Kakuyri Tama (Eu moro na cidade)â, da autora indĂgena amazonense MĂĄrcia Kambeba. Esta pesquisa se coloca como teĂłrica e de cunho bibliogrĂĄfico. Julgamos que este tema seja relevante para pensar os diferentes tipos de literaturas emergentes na sociedade atual, assim como a literatura indĂgena. A poesia indĂgena de MĂĄrcia Kambeba nos revela ter um forte aporte na memĂłria, na oralidade, na afirmação da identidade indĂgena, entre outros pontos, dando voz Ă s mulheres indĂgenas e reafirmando a importĂąncia de seus territĂłrios sociais.This paper was created from possible interpretations of the poem "Ay Kakuyri Tama (I live in the city)", by the indigenous Amazonian author MĂĄrcia Kambeba. This research is presented as a theoretical one and of a bibliographical nature. We believe that this theme is relevant to think about the different types of literatures emerging in today's society, as well as indigenous literature. The indigenous poetry of MĂĄrcia Kambeba reveals to us a strong dependency on memory and orality, the affirmation of indigenous identity, among other points, giving voice to indigenous women and reaffirming the importance of their social territories
Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system
The bacterial human pathogen Helicobacter pylori produces a type IV secretion system ( cag T4SS) to inject the oncoprotein CagA into gastric cells. The cag T4SS external pilus mediates attachment of the apparatus to the target cell and the delivery of CagA. While the composition of the pilus is unclear, CagI is present at the surface of the bacterium and required for pilus formation. Here, we have investigated the properties of CagI by an integrative structural biology approach. Using Alpha Fold 2 and Small Angle X-ray scattering, it was found that CagI forms elongated dimers mediated by rod-shape N-terminal domains (CagI N ) prolonged by globular C-terminal domains (CagI C ). Three Designed Ankyrin Repeat Proteins (DARPins) K2, K5 and K8 selected against CagI interacted with CagI C with subnanomolar affinities. The crystal structures of the CagI:K2 and CagI:K5 complexes were solved and identified the interfaces between the molecules, thereby providing a structural explanation for the difference in affinity between the two binders. Purified CagI and CagI C were found to interact with adenocarcinoma gastric (AGS) cells, induced cell spreading and the interaction was inhibited by K2. The same DARPin inhibited CagA translocation by up to 65% in AGS cells while inhibition levels were 40% and 30% with K8 and K5, respectively. Our study suggests that CagI C plays a key role in cag T4SS-mediated CagA translocation and that DARPins targeting CagI represent potent inhibitors of the cag T4SS, a crucial risk factor for gastric cancer development.Bases structurale du systĂšme de secretion de type IV d'Helicobacter pyloriBases structurales et molĂ©culaires de l'exploitation de l'integrin a5Ă1 par le systĂšme de sĂ©crĂ©tion de type IV d'Helicobacter pylor
Dipstick Test for Rapid Diagnosis of Shigella dysenteriae 1 in Bacterial Cultures and Its Potential Use on Stool Samples
International audienceBACKGROUND: We describe a test for rapid detection of S. dysenteriae 1 in bacterial cultures and in stools, at the bedside of patients. METHODOLOGY/PRINCIPAL FINDINGS: The test is based on the detection of S. dysenteriae 1 lipopolysaccharide (LPS) using serotype 1-specific monoclonal antibodies coupled to gold particles and displayed on a one-step immunochromatographic dipstick. A concentration as low as 15 ng/ml of LPS was detected in distilled water and in reconstituted stools in 10 minutes. In distilled water and in reconstituted stools, an unequivocal positive reaction was obtained with 1.6Ă10ⶠCFU/ml and 4.9Ă10ⶠCFU/ml of S. dysenteriae 1, respectively. Optimal conditions to read the test have been determined to limit the risk of ambiguous results due to appearance of a faint yellow test band in some negative samples. The specificity was 100% when tested with a battery of Shigella and unrelated strains in culture. When tested on 328 clinical samples in India, Vietnam, Senegal and France by laboratory technicians and in Democratic Republic of Congo by a field technician, the specificity (312/316) was 98.7% (95% CI:96.6-99.6%) and the sensitivity (11/12) was 91.7% (95% CI:59.8-99.6%). Stool cultures and the immunochromatographic test showed concordant results in 98.4 % of cases (323/328) in comparative studies. Positive and negative predictive values were 73.3% (95% CI:44.8-91.1%) and 99.7% (95% CI:98-100%). CONCLUSION: The initial findings presented here for a simple dipstick-based test to diagnose S. dysenteriae 1 demonstrates its promising potential to become a powerful tool for case management and epidemiological surveys
Altimetry for the future: Building on 25 years of progress
In 2018 we celebrated 25 years of development of radar altimetry, and the progress achieved by this methodology in the fields of global and coastal oceanography, hydrology, geodesy and cryospheric sciences. Many symbolic major events have celebrated these developments, e.g., in Venice, Italy, the 15th (2006) and 20th (2012) years of progress and more recently, in 2018, in Ponta Delgada, Portugal, 25 Years of Progress in Radar Altimetry. On this latter occasion it was decided to collect contributions of scientists, engineers and managers involved in the worldwide altimetry community to depict the state of altimetry and propose recommendations for the altimetry of the future. This paper summarizes contributions and recommendations that were collected and provides guidance for future mission design, research activities, and sustainable operational radar altimetry data exploitation. Recommendations provided are fundamental for optimizing further scientific and operational advances of oceanographic observations by altimetry, including requirements for spatial and temporal resolution of altimetric measurements, their accuracy and continuity. There are also new challenges and new openings mentioned in the paper that are particularly crucial for observations at higher latitudes, for coastal oceanography, for cryospheric studies and for hydrology. The paper starts with a general introduction followed by a section on Earth System Science including Ocean Dynamics, Sea Level, the Coastal Ocean, Hydrology, the Cryosphere and Polar Oceans and the ââGreenâ Ocean, extending the frontier from biogeochemistry to marine ecology. Applications are described in a subsequent section, which covers Operational Oceanography, Weather, Hurricane Wave and Wind Forecasting, Climate projection. Instrumentsâ development and satellite missionsâ evolutions are described in a fourth section. A fifth section covers the key observations that altimeters provide and their potential complements, from other Earth observation measurements to in situ data. Section 6 identifies the data and methods and provides some accuracy and resolution requirements for the wet tropospheric correction, the orbit and other geodetic requirements, the Mean Sea Surface, Geoid and Mean Dynamic Topography, Calibration and Validation, data accuracy, data access and handling (including the DUACS system). Section 7 brings a transversal view on scales, integration, artificial intelligence, and capacity building (education and training). Section 8 reviews the programmatic issues followed by a conclusion
Altimetry for the future: building on 25 years of progress
In 2018 we celebrated 25âŻyears of development of radar altimetry, and the progress achieved by this methodology in the fields of global and coastal oceanography, hydrology, geodesy and cryospheric sciences. Many symbolic major events have celebrated these developments, e.g., in Venice, Italy, the 15th (2006) and 20th (2012) years of progress and more recently, in 2018, in Ponta Delgada, Portugal, 25 Years of Progress in Radar Altimetry. On this latter occasion it was decided to collect contributions of scientists, engineers and managers involved in the worldwide altimetry community to depict the state of altimetry and propose recommendations for the altimetry of the future. This paper summarizes contributions and recommendations that were collected and provides guidance for future mission design, research activities, and sustainable operational radar altimetry data exploitation. Recommendations provided are fundamental for optimizing further scientific and operational advances of oceanographic observations by altimetry, including requirements for spatial and temporal resolution of altimetric measurements, their accuracy and continuity. There are also new challenges and new openings mentioned in the paper that are particularly crucial for observations at higher latitudes, for coastal oceanography, for cryospheric studies and for hydrology.
The paper starts with a general introduction followed by a section on Earth System Science including Ocean Dynamics, Sea Level, the Coastal Ocean, Hydrology, the Cryosphere and Polar Oceans and the âGreenâ Ocean, extending the frontier from biogeochemistry to marine ecology. Applications are described in a subsequent section, which covers Operational Oceanography, Weather, Hurricane Wave and Wind Forecasting, Climate projection. Instrumentsâ development and satellite missionsâ evolutions are described in a fourth section. A fifth section covers the key observations that altimeters provide and their potential complements, from other Earth observation measurements to in situ data. Section 6 identifies the data and methods and provides some accuracy and resolution requirements for the wet tropospheric correction, the orbit and other geodetic requirements, the Mean Sea Surface, Geoid and Mean Dynamic Topography, Calibration and Validation, data accuracy, data access and handling (including the DUACS system). Section 7 brings a transversal view on scales, integration, artificial intelligence, and capacity building (education and training). Section 8 reviews the programmatic issues followed by a conclusion
Gestion, contrÎle et maßtrise des Zones à AtmosphÚre ContrÎlée dans le cadre des procédés aseptiques
MONTPELLIER-BU Pharmacie (341722105) / SudocSudocFranceF
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