SPC-based model for evaluation of training processes in industrial context

Purpose: This article aims to present successful practices in the management of training processes based on virtual reality and augmented reality, namely a strategy for evaluating the process with the principle of continuous improvement in mind, and monitoring its performance in terms of productivity and waste levels. It is proposed to apply Statistical Process Control (SPC) tools to develop control charts for monitoring individual events (i-charts). Design/methodology/approach: The methodology is based on a case study developed in an industrial project and is guided by a literature review on Work-Based Learning (WBL) and SPC. Findings: The developed work shows that SPC tools are suitable for supporting decision making in situations where the data to be analyzed is generated by human-computer interactions, e.g., involving students and virtual learning environments. Originality/value: The innovative aspect presented in the article lies in the evaluation of the effectiveness of pedagogical resources arranged in simulation environments based on virtual and augmented reality. The accumulated knowledge about the application of SPC in service areas, and others that demand data analysis, reinforces the hypothesis of the suitability of its application in the case presented. This is an original application of SPC, normally used in business processes quality control, but which in this case is applied in an innovative way to the evaluation of industrial training processes, with the same spirit for which it was designed, i.e. to provide the means to manage the quality of a processPeer Reviewe

Single Nucleotide Polymorphisms Of The Gjb2 And Gjb6 Genes Are Associated With Autosomal Recessive Nonsyndromic Hearing Loss

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Single nucleotide polymorphisms (SNPs) are important markers in many studies that link DNA sequence variations to phenotypic changes; such studies are expected to advance the understanding of human physiology and elucidate the molecular basis of diseases. The DFNB1 locus, which contains the GJB2 and GJB6 genes, plays a key role in nonsyndromic hearing loss. Previous studies have identified important mutations in this locus, but the contribution of SNPs in the genes has not yet been much investigated. The aim of this study was to investigate the association of nine polymorphisms located within the DFNB1 locus with the occurrence of autosomal recessive nonsyndromic hearing loss (ARNSHL). The SNPs rs3751385 (C/T), rs7994748 (C/T), rs7329857 (C/T), rs7987302 (G/A), rs7322538 (G/A), rs9315400 (C/T), rs877098 (C/T), rs945369 (A/C), and rs7333214 (T/G) were genotyped in 122 deaf patients and 132 healthy controls using allele-specific PCR. There were statistically significant differences between patients and controls, in terms of allelic frequencies in the SNPs rs3751385, rs7994748, rs7329857, rs7987302, rs945369, and rs7333214 (P < 0.05). No significant differences between the two groups were observed for rs7322538, rs9315400, and rs877098. Our results suggest that SNPs present in the GJB2 and GJB6 genes may have an influence on ARNSHL in humans.Fundacao Herminio Ometto/FHOConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Desenvolvimento de um laboratório remoto de FPGA: Indo em direção a um laboratório híbrido

Este artigo descreve o desenvolvimento de um laboratório remoto de FPGApara o aprendizado de circuitos digitais. A solução proposta (laboratório remoto) faz uso da aplicação VirtualHere e se integra ao software WiRED Panda, o qual é um simulador de circuitos de lógica digital (laboratório virtual). A solução proposta foi implantada no setor de Tecnologia de Informação de uma universidade e validada por meio de testes e questionários com os alunos participantes da pesquisa, obtendo-se resultados promissores quanto a sua utilização

Single Nucleotide Polymorphisms Of The Gjb2 And Gjb6 Genes Are Associated With Autosomal Recessive Nonsyndromic Hearing Loss.

Single nucleotide polymorphisms (SNPs) are important markers in many studies that link DNA sequence variations to phenotypic changes; such studies are expected to advance the understanding of human physiology and elucidate the molecular basis of diseases. The DFNB1 locus, which contains the GJB2 and GJB6 genes, plays a key role in nonsyndromic hearing loss. Previous studies have identified important mutations in this locus, but the contribution of SNPs in the genes has not yet been much investigated. The aim of this study was to investigate the association of nine polymorphisms located within the DFNB1 locus with the occurrence of autosomal recessive nonsyndromic hearing loss (ARNSHL). The SNPs rs3751385 (C/T), rs7994748 (C/T), rs7329857 (C/T), rs7987302 (G/A), rs7322538 (G/A), rs9315400 (C/T), rs877098 (C/T), rs945369 (A/C), and rs7333214 (T/G) were genotyped in 122 deaf patients and 132 healthy controls using allele-specific PCR. There were statistically significant differences between patients and controls, in terms of allelic frequencies in the SNPs rs3751385, rs7994748, rs7329857, rs7987302, rs945369, and rs7333214 (P < 0.05). No significant differences between the two groups were observed for rs7322538, rs9315400, and rs877098. Our results suggest that SNPs present in the GJB2 and GJB6 genes may have an influence on ARNSHL in humans.201531872

abCDEuropa: guida al wiki dei CDE italiani

Il wiki dei CDE italiani è uno strumento pensato e creato specificamente per l’uso online poiché ha una struttura reticolare di rimandi incrociati invece di un’esposizione lineare. Questa breve guida non intende quindi riproporre il wiki dei CDE, che è uno strumento dinamico in continua evoluzione e aggiornamento, bensì fornire in una pluralità di supporti oltre al web - carta, libro elettronico - indicazioni generali e sintetiche sui principali contenuti del wiki

Single nucleotide polymorphisms of the GJB2 and GJB6 genes are associated with autosomal recessive nonsyndromic hearing loss

Single nucleotide polymorphisms (SNPs) are important markers in many studies that link DNA sequence variations to phenotypic changes; such studies are expected to advance the understanding of human physiology and elucidate the molecular basis of diseases. The DFNB1 locus, which contains the GJB2 and GJB6 genes, plays a key role in nonsyndromic hearing loss. Previous studies have identified important mutations in this locus, but the contribution of SNPs in the genes has not yet been much investigated. The aim of this study was to investigate the association of nine polymorphisms located within the DFNB1 locus with the occurrence of autosomal recessive nonsyndromic hearing loss (ARNSHL). The SNPs rs3751385 (C/T), rs7994748 (C/T), rs7329857 (C/T), rs7987302 (G/A), rs7322538 (G/A), rs9315400 (C/T), rs877098 (C/T), rs945369 (A/C), and rs7333214 (T/G) were genotyped in 122 deaf patients and 132 healthy controls using allele-specific PCR. There were statistically significant differences between patients and controls, in terms of allelic frequencies in the SNPs rs3751385, rs7994748, rs7329857, rs7987302, rs945369, and rs7333214 (P < 0.05). No significant differences between the two groups were observed for rs7322538, rs9315400, and rs877098. Our results suggest that SNPs present in the GJB2 and GJB6 genes may have an influence on ARNSHL in humans2015CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFundacao Herminio Ometto/FH

Interaction of Human Serum Album and C60 Aggregates in Solution

An important property of C60 in aquatic ecotoxicology is that it can form stable aggregates with nanoscale dimensions, namely nC60. Aggregation allows fullerenes to remain suspended for a long time, and the reactivity of individual C60 is substantially altered in this aggregate form. Herein, we investigated the interaction of nC60 and human serum album (HSA) using the methods of fluorescence, fluorescence dynamics, circular dichroism (CD), and site marker competitive experiments. We proposed a binding model consistent with the available experimental results for the interactions of nC60 with HSA. During the interaction process, the structure and conformation of HSA were affected, leading to functional changes of drug binding sites of HSA

Warranty Data Analysis: A Review

Warranty claims and supplementary data contain useful information about product quality and reliability. Analysing such data can therefore be of benefit to manufacturers in identifying early warnings of abnormalities in their products, providing useful information about failure modes to aid design modification, estimating product reliability for deciding on warranty policy and forecasting future warranty claims needed for preparing fiscal plans. In the last two decades, considerable research has been conducted in warranty data analysis (WDA) from several different perspectives. This article attempts to summarise and review the research and developments in WDA with emphasis on models, methods and applications. It concludes with a brief discussion on current practices and possible future trends in WDA

A Shared Global Heritage. Architectural History, Conservation, and Preservation

A series of studies on fascinating cases in architectural history, the essays in this collection reveal the complexity of the current issues in the field, draw attention to the value of architectural heritage and the risks it faces, and suggest possible interpretations as well as alternative methods in the preservation, conservation, reconstruction, and use of architectural heritage. Each essayist has been in residence at Columbia's Italian Academy with a fellowship supported by the Sidney J. Weinberg Jr. Foundation. Edited by B. Faedda Authors: S. Al-Qaisi, P. Aykac, S. Crane, G. de Felice, D. La Monica, F. Marcorin, C. Ruggero, A. Zunic