Chronic recurrent non-specific parotitis: a case report and review

Background: Chronic recurrent non-specific parotitis is characterized by recurrent episodes of swelling and pain of unknown etiology in the parotid gland. Sialography is a hallmark in the diagnosis of salivary gland disorders; newer imaging modalities like CT-Sialography, sialoendoscopy and MRI can be used. Various treatment modalities have been tried, from conservative approach to surgical excision depending on the recurrence rate and severity of the condition. Although symptomatic treatment with antibiotics and analgesic, injection of intraductal medicament, aggressive treatment like duct ligation or excision of gland are some of the treatment modalities, there is no established algorithm as to which treatment method should be opted in such clinical situation.Case Detail: A 20 years old male patient reported with pain and salty taste in the mouth that had began before a week. Examination revealed an elevated right parotid papilla; ropy, cloudy appearing saliva was oozing out on milking the gland. Unstimulated and stimulated whole salivary flow rate was assessed using drooling method. Sialography was used as a diagnostic and a therapeutic aid. In our case, sialography as a treatment showed a good response with no recurrence after two years of follow-up. We highlighted the role of sialography as a therapeutic aid.Conclusion: Recurrent attacks significantly affect the quality of life and also lead to progressive gland destruction. Preventing or reducing the frequency of recurrence remains the goal of therapeutic procedure. Hence, conventional sialography is useful in the diagnosis and also effective as a therapeutic aid in recurrent parotitis.Keywords: Chronic recurrent Parotitis, Non specific Parotitis, Sialograph

Jaw bone metastasis from Lung cancer as sole primary source : a systematic review

Lung cancer is one of the leading causes of death worldwide. Lung cancer metastasis to oral region is very rare. Very few research work has been conducted till date to analyse the jaw bone metastasis from Lung cancer as the primary source. The goal of th

Lung cancer metastasis to oral soft tissues; Systematic review of 122 cases

Lung cancer metastasis to oral region is very rare. Studies have been published analysing the cases of metastatic tumours to the oral cavity by many researchers. But very few research work has been conducted till date to analyse only the oral soft tissu

Six-membered ring systems: with O and/or S atoms

A large variety of publications involving O- and S-6-membered ring systems have appeared in 2017. The importance of these heterocyclic compounds is highlighted by the huge number of publications on the total synthesis of natural oxygen derivatives and of other communications dedicated to synthetic derivatives. Reviews on stereoselective organocatalytic synthesis of tetrahydropyrans (17EJO4666), of tetrahydropyrans and their application in total synthesis of natural products (17CSR1661), on the synthesis of the less thermodynamically stable 2,6-trans-tetrahydropyrans (17S4899), on enantioselective synthesis of polyfunctionalized pyran and chromene derivatives (17TA1462), and on enantioselective and racemic total synthesis of camptothecins, including the formation of their pyran-2-one ring (17SL1134), have appeared. Advances in the transition metal-catalyzed synthesis of pyran-2/4-ones (17TL263), N-heterocyclic carbene (NHC)-catalyzed achiral synthesis of pyran-2-one, coumarin and (thio)chromone derivatives (17OBC4731), on the synthesis and transformation of 2H-pyran-2-ones (17T2529) and 2-styrylchromones (17EJO3115) into other heterocyclic compounds, have been surveyed. The strategies to build up the tetrahydropyranyl core of brevisamide (17H(95)81) and the reactions of ketyl radicals, generated from carbonyl derivatives under transition-metal photoredox-catalyzed conditions, leading to isochromen- and chroman-type compounds (17CC13093) were disclosed. Developments in the synthesis of pentafluorosulfanyl(chromene and coumarin) derivatives (17TL4803), photoswitchable D9-tetrahydrocannabinol derivatives (17JA18206), and aminobenzopyranoxanthenes with nitrogen-containing rings (17JOC13626) have been studied.info:eu-repo/semantics/publishedVersio

Opinion of dentists and gynecologists on the link between oral health and preterm low birth weight: “Preconception care - treat beyond the box”

Background: Periodontal diseases are known to set an inflammatory response at the systemic level which can adversely affect the pregnancy outcomes, and many patients are unaware of this association. Health-care providers play a vital role in educating patients toward maintaining good oral health; hence, our study was planned to evaluate the knowledge, attitude, and practices of dentists' and gynecologists' concerning this link. In addition, referral to the dentists' during the preconception period was also emphasized. Materials and Methods: This was a cross-sectional questionnaire survey conducted among dentists and gynecologists' in the city of Mysore. The participants were divided into two groups and were asked specific questions about the association between oral health and preterm low birth weight (PTLB). Group I constituted the dentists possessing both graduate and postgraduate degree and Group II were the gynecologists'. Results: Seventy-nine percent of the total participants agreed about the link between periodontal health and PTLB. Dentists were more aware of the periodontal changes during pregnancy and stressed on frequent dental checkup during pregnancy. Preconception care was a neglected part of the protocol by the gynecologists', and only 12% of them referred patients to a dentist in the preconception period. Factors significantly associated with knowledge in logistic regression analyses were older age, dentists and the years of experience (>5 years). Conclusion: Knowledge about oral health is important, to maintain good general health; hence, health workers should not miss opportunities to contribute to this health promotion. An integrated work by the dentists and gynecologists may reduce the adverse pregnancy outcomes associated with periodontal diseases

Stereoselective total synthesis of (+)-polyrhacitide A

A facile stereoselective total synthesis of secondary metabolite (+)-polyrhacitide A is described. Stereoselective aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction are the key steps involved in the target synthesis

Formal total synthesis of cyanolide A

Formal total synthesis of cyanolide A, aglycosidic dimeric macrolide is accomplished. The key reactions involved are asymmetric acetate aldol reaction, CBS reduction, and Shiina's lactonization