In-transit sentinel lymph nodes predicted by F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography

Although the in-transit lymph node is a well-known issue in malignant melanoma, it is not documented sufficiently in breast cancer. In this case report an in-transit lymph node demonstrated by both PET/CT and sentinel lymph node mapping and diagnosed by pathology is reported

Is TI-RADS classification and Score Modified Method of thyroid nodules can be effective for evaluation of Thyroid Incidentalomas on FDG PET-CT imaging

Background: Flourodeoyglucose Positron Emission Tomography-Computed Tomography (FDG PET-CT) provides information about the anatomic structures and metabolic activities of tumors. The incidence of thyroid incidentaloma is rare on FDG PET-CT but it is related to malignancy when it is detected to be high. Although, patients who are already treated with another primary tumor can not be searched for second thyroid malignancy each time. The aim of this study was to evaluate TI RADS classification based on a score modified according to ultrasound (US) criteria for malignancy of thyroid nodules determined on FDG PET/CT imaging.Materiels &amp; Methods: Patients’ data diagnosed with a variety of cancer evaluated, retrospectively. All patients underwent PET/ CT examinations for cancer screening, staging, restaging, and detection of suspected recurrence. Patients with thyroid nodules on CT imaging provided by PET/ CT were selected.Results: Patients are divided into two groups. Group I included a total of 29 patients (24 women/ 5 men-age range: 30-80 years-mean age:57) with thyroid final histopathology results. Group II included a total of 24 (18 women/6 men-age range: 47-80, mean: 66.6) patients without pathology results of thyroid nodules. Of the 29 patients in group I, 20 patients had benign (69%) and 9 patients had malign (31%) histopathology results. Mean SUV max value in benign and malignant thyroid nodules were 5.3 (Range: 1-18) and 17.54 (Range: 7-35), respectively. Mean maximum standardized uptake value in malignant thyroid lesions was higher than that of benign lesions (P&lt; 0.0001). Most of the benign thyroid nodules (85%) had TI RADS 1-3 classification while most malignant nodules had TI RADS 4-6 (87.5%). Mean SUV max value in thyroid nodules were 5.35 (Range: 1-43) in Group II follow-up patients. Thyroid nodules were TI RADS 1-5 classification in this group, most of which were 1-3 as benign thyroid nodules in group I patients. This group consisted of patients who could not have a thyroid biopsy due to primary malignancy diagnoses and advanced stages. None of them were diagnosed for thyroid malignancy or progressed during follow-up.&nbsp;Conclusions: Patients who do not have short expected duration of life due to other primary tumors should be evaluated with US. TI RADS classification based on a score modified according to ultrasound criteria for malignancy of thyroid nodules determined on FDG PET/CT imaging can be used for oncological patients.</p

Quality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey

balkan, ilker inanc/0000-0002-8977-5931; Altindis, Mustafa/0000-0003-0411-9669; Sahin, Ahmet Ziyaettin/0000-0003-1060-6746; atilla, aynur/0000-0001-8027-1991WOS: 000386954300001PubMed: 27809934Background: The aim of this study was to assess health-related quality of life (HRQOL) among chronic hepatitis B (CHB) patients in Turkey and to study related factors. Methods: This multicenter study was carried out between January 01 and April 15, 2015 in Turkey in 57 centers. Adults were enrolled and studied in three groups. Group 1: Inactive HBsAg carriers, Group 2: CHB patients receiving antiviral therapy, Group 3: CHB patients who were neither receiving antiviral therapy nor were inactive HBsAg carriers. Study data was collected by face-to-face interviews using a standardized questionnaire, Short Form-36 (SF-36) and Hepatitis B Quality of Life (HBQOL). Values equivalent to p < 0.05 in analyses were accepted as statistically significant. Results: Four thousand two hundred fifty-seven patients with CHB were included in the study. Two thousand five hundred fifty-nine (60.1 %) of the patients were males. Groups 1, 2 and 3, consisted of 1529 (35.9 %), 1721 (40.4 %) and 1007 (23.7 %) patients, respectively. The highest value of HRQOL was found in inactive HBsAg carriers. We found that total HBQOL score increased when antiviral treatment was used. However, HRQOL of CHB patients varied according to their socio-demographic properties. Regarding total HBQOL score, a higher significant level of HRQOL was determined in inactive HBV patients when matched controls with the associated factors were provided. Conclusions: The HRQOL score of CHB patients was higher than expected and it can be worsen when the disease becomes active. Use of an antiviral therapy can contribute to increasing HRQOL of patients

Quality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey

Background: The aim of this study was to assess health-related quality of life (HRQOL) among chronic hepatitis B (CHB) patients in Turkey and to study related factors

The prevalence of childhood psychopathology in Turkey: a cross-sectional multicenter nationwide study (EPICPAT-T).

Aim: The aim of this study was to determine the prevalence of childhood psychopathologies in Turkey

The prevalence of childhood psychopathology in Turkey: a cross-sectional multicenter nationwide study (EPICPAT-T)

Conclusion: This is the largest and most comprehensive epidemiological study to determine the prevalence of psychopathologies in children and adolescents in Turkey. Our results partly higher than, and partly comparable to previous national and international studies. It also contributes to the literature by determining the independent predictors of psychopathologies in this age group

Prevalence of Childhood Affective disorders in Turkey: An epidemiological study

Aim: To determine the prevalence of affective disorders in Turkey among a representative sample of Turkish population. Methods: This study was conducted as a part of the "The Epidemiology of Childhood Psychopathology in Turkey" (EPICPAT-T) Study, which was designed by the Turkish Association of Child and Adolescent Mental Health. The inclusion criterion was being a student between the second and fourth grades in the schools assigned as study centers. The assessment tools used were the K-SADS-PL, and a sociodemographic form that was designed by the authors. Impairment was assessed via a 3 point-Likert type scale independently rated by a parent and a teacher. Results: A total of 5842 participants were included in the analyses. The prevalence of affective disorders was 2.5 % without considering impairment and 1.6 % when impairment was taken into account. In our sample, the diagnosis of bipolar disorder was lacking, thus depressive disorders constituted all the cases. Among depressive disorders with impairment, major depressive disorder (MDD) (prevalence of 1.06%) was the most common, followed by dysthymia (prevalence of 0.2%), adjustment disorder with depressive features (prevalence of 0.17%), and depressive disorder-NOS (prevalence of 0.14%). There were no statistically significant gender differences for depression. Maternal psychopathology and paternal physical illness were predictors of affective disorders with pervasive impairment. Conclusion: MDD was the most common depressive disorder among Turkish children in this nationwide epidemiological study. This highlights the severe nature of depression and the importance of early interventions. Populations with maternal psychopathology and paternal physical illness may be the most appropriate targets for interventions to prevent and treat depression in children and adolescents