26 research outputs found

    A Survey on Semantic Communications for Intelligent Wireless Networks

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    With deployment of 6G technology, it is envisioned that competitive edge of wireless networks will be sustained and next decade's communication requirements will be stratified. Also 6G will aim to aid development of a human society which is ubiquitous and mobile, simultaneously providing solutions to key challenges such as, coverage, capacity, etc. In addition, 6G will focus on providing intelligent use-cases and applications using higher data-rates over mill-meter waves and Tera-Hertz frequency. However, at higher frequencies multiple non-desired phenomena such as atmospheric absorption, blocking, etc., occur which create a bottleneck owing to resource (spectrum and energy) scarcity. Hence, following same trend of making efforts towards reproducing at receiver, exact information which was sent by transmitter, will result in a never ending need for higher bandwidth. A possible solution to such a challenge lies in semantic communications which focuses on meaning (context) of received data as opposed to only reproducing correct transmitted data. This in turn will require less bandwidth, and will reduce bottleneck due to various undesired phenomenon. In this respect, current article presents a detailed survey on recent technological trends in regard to semantic communications for intelligent wireless networks. We focus on semantic communications architecture including model, and source and channel coding. Next, we detail cross-layer interaction, and various goal-oriented communication applications. We also present overall semantic communications trends in detail, and identify challenges which need timely solutions before practical implementation of semantic communications within 6G wireless technology. Our survey article is an attempt to significantly contribute towards initiating future research directions in area of semantic communications for intelligent 6G wireless networks

    Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

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    Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020

    Impact of Human Settlements on Diversity of Range Vegetation

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    The rapidly increasing population of human beings in semi-arid areas is often considered as a major factor of land degradation. Only a few studies have examined the dynamics of human settlements on the composition, diversity, structure and palatability of range vegetation in Southern Punjab Pakistan. The current study aims to assess whether the distance from settlements had any effect on the range vegetation’s diversity and cover. In order to determine the impact of human settlements on the vegetation, the sampling area (Thal rangeland) was classified into three categories, i.e., Near (1–2 km from human communities), Away (2–4 km from human communities), and Far (4–6 km from human settlements). A total of 75 transects in all of the three sites were placed in the study sites. Along the transects, a quadrate of 1 m2 after every 10 m was randomly placed. The study site yielded floral diversity of a total of 29 species, representing 23 genera and belonging to 9 families. Results showed that the areas away from the human communities had higher species diversity (20), while the site near to human settlements depicted lower diversity (14). It was observed that, although the site near to communities had lower diversity, it depicted higher plant density, while the highest diversity along with the lowest plant density was observed in sites away from the communities. The study concluded that the diversity of range grasses, especially desirable species, was affected by distance to human settlements. These findings could be useful to detect flora changes, establish habitat protection priorities and improve efforts for conserving natural landscapes

    Impact of Human Settlements on Diversity of Range Vegetation

    No full text
    The rapidly increasing population of human beings in semi-arid areas is often considered as a major factor of land degradation. Only a few studies have examined the dynamics of human settlements on the composition, diversity, structure and palatability of range vegetation in Southern Punjab Pakistan. The current study aims to assess whether the distance from settlements had any effect on the range vegetation’s diversity and cover. In order to determine the impact of human settlements on the vegetation, the sampling area (Thal rangeland) was classified into three categories, i.e., Near (1–2 km from human communities), Away (2–4 km from human communities), and Far (4–6 km from human settlements). A total of 75 transects in all of the three sites were placed in the study sites. Along the transects, a quadrate of 1 m2 after every 10 m was randomly placed. The study site yielded floral diversity of a total of 29 species, representing 23 genera and belonging to 9 families. Results showed that the areas away from the human communities had higher species diversity (20), while the site near to human settlements depicted lower diversity (14). It was observed that, although the site near to communities had lower diversity, it depicted higher plant density, while the highest diversity along with the lowest plant density was observed in sites away from the communities. The study concluded that the diversity of range grasses, especially desirable species, was affected by distance to human settlements. These findings could be useful to detect flora changes, establish habitat protection priorities and improve efforts for conserving natural landscapes

    <i>ADAMTS1</i>, <i>MPDZ</i>, <i>MVD</i>, and <i>SEZ6</i>:candidate genes for autosomal recessive nonsyndromic hearing impairment

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    Hearing impairment (HI) is a common disorder of sensorineural function with a highly heterogeneous genetic background. Although substantial progress has been made in the understanding of the genetic etiology of hereditary HI, many genes implicated in HI remain undiscovered. Via exome and Sanger sequencing of DNA samples obtained from consanguineous Pakistani families that segregate profound prelingual sensorineural HI, we identified rare homozygous missense variants in four genes (ADAMTS1, MPDZ, MVD, and SEZ6) that are likely the underlying cause of HI. Linkage analysis provided statistical evidence that these variants are associated with autosomal recessive nonsyndromic HI. In silico analysis of the mutant proteins encoded by these genes predicted structural, conformational or interaction changes. RNAseq data analysis revealed expression of these genes in the sensory epithelium of the mouse inner ear during embryonic, postnatal, and adult stages. Immunohistochemistry of the mouse cochlear tissue, further confirmed the expression of ADAMTS1, SEZ6, and MPDZ in the neurosensory hair cells of the organ of Corti, while MVD expression was more prominent in the spiral ganglion cells. Overall, supported by in silico mutant protein analysis, animal models, linkage analysis, and spatiotemporal expression profiling in the mouse inner ear, we propose four new candidate genes for HI and expand our understanding of the etiology of HI

    Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome

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