79 research outputs found
Distribution of glycinergic neurons in the brain of glycine transporter-2 Tg(glyt2:gfp) transgenic adult zebrafish:Relation with brain-spinal descending systems
Nebular and stellar properties of a metal poor HII galaxy at z=3.36
We have characterized the physical properties (electron temperature, density,
metallicity) of the ionized gas and the ionizing population (age, metallicity,
presence of WR stars) in the Lynx arc at z=3.36. This is a low metallicity
(~10% solar) HII galaxy which is undergoing a burst of star formation of <5 Myr
age. One possible scenario that explains the emission line spectrum of the Lynx
arc, the large strength of the nitrogen lines and the HeII emission is that the
object has experienced a merger event that has triggered a burst of star
formation. WR stars have formed that contribute to a fast enrichment of the ISM
and its overabundance of nitrogen.Comment: 12 pages, 1 figure. Accepted for publication in MNRA
I Zw 18 as morphological paradigm for rapidly assembling high-z galaxies
IZw18, ever since regarded as the prototypical blue compact dwarf (BCD)
galaxy, is, quite ironically, the most atypical BCD known. This is because its
large exponential low-surface brightness envelope is not due to an old stellar
host but entirely due to extended nebular emission (ne) (Papaderos et al. 2002;
P02). We study IZw18 and IZw18C down to an unprecedently faint surface
brightness level using HST ACS data.
We argue that the properties of IZw18C can be consistently accounted for by
propagating star formation over the past ~100 Myr, in combination with stellar
diffusion and the associated radial stellar mass filtering effect (P02).
As for IZw18, we find that ne extends out to ~16 stellar scale lengths and
provides at least 1/3 of the total optical emission.
The case of IZw18 suggests caution in studies of distant galaxies in dominant
stages of their evolution, rapidly assembling their stellar mass at high
specific star formation rates (SSFRs). It calls attention to the fact that ne
is not necessarily cospatial with the underlying ionizing and non-ionizing
stellar background, neither has to scale with its surface density. The
prodigious energetic output during dominant phases of galaxy evolution may
result in large exponential ne envelopes, extending much beyond the still
compact stellar component, just like in IZw18. Therefore, the morphological
paradigm of IZw18, while probably unique in the nearby Universe, may be
ubiquitous among high-SSFR galaxies at high redshift. Using IZw18 as reference,
we show that extended ne may introduce substantial observational biases and
significantly affect fundamental galaxy relations. Among others, we show that
the surface brightness profiles of distant morphological analogs to IZw18 may
be barely distinguishable from Sersic profiles with an exponent 2<n<5, thus
mimicking the profiles of massive galaxy spheroids. (abridged)Comment: 22 pages, 15 figures, Accepted for publication in Astronomy and
Astrophysic
Serotonin inhibits axonal regeneration of identifiable descending neurons after a complete spinal cord injury in lampreys
Classical neurotransmitters are mainly known for their roles as neuromodulators, but they also play important roles in the control of developmental and regenerative processes. Here, we used the lamprey model of spinal cord injury to study the effect of serotonin in axon regeneration at the level of individually identifiable descending neurons. Pharmacological and genetic manipulations after a complete spinal cord injury showed that endogenous serotonin inhibits axonal regeneration in identifiable descending neurons through the activation of serotonin 1A receptors and a subsequent decrease in cyclic adenosine monophosphate (cAMP) levels. RNA sequencing revealed that changes in the expression of genes that control axonal guidance could be a key factor determining the serotonin effects during regeneration. This study provides new targets of interest for research in non-regenerating mammalian models of traumatic central nervous system injuries and extends the known roles of serotonin signalling during neuronal regeneration.
This article has an associated First Person interview with the first author of the paper
The glycinergic system of the CNS of the sea lamprey, "Petromyzon marinus", a developmental study and comparison with GABA
Servicio de Imagen del Instituto de Neurociencias: del cerebro a las moléculas
Póster presentado al Encuentro de Investigación: Buscando Sinergias, celebrado el 7 de junio de 2022 en el Salón de Actos del Hospital General Dr. Balmis (Alicante).Peer reviewe
Dispositivo de protección ocular ante infecciones destinado a ser colocado en los oculares de un equipo de microscopía
Dispositivo (1) de protección ocular ante infecciones destinado a ser colocado en los oculares (12) de un equipo de microscopía (2), donde dicho dispositivo (1) está caracterizado porque comprende: - un cilindro abierto (3) destinado a cubrir el ocular (12) del equipo de microscopía (2), dicho cilindro abierto (3) provisto de una porción proximal (4), una porción distal (5), una porción interior (6) y una porción exterior (7), donde la porción proximal (4) está provista de un anillo interior (8) y la porción interior (6) comprende al menos una primera muesca (9) que ejerce de tope con el ocular (12) del equipo de microscopía (2) y está destinada a sujetar una lámina transparente (11) intercambiable introducida en la porción proximal (4) dentro del cilindro abierto (3) entre el anillo interior (8) y la primera muesca (9)Peer reviewedConsejo Superior de Investigaciones Científicas (España), Universidad Miguel Hernández de ElcheU Solicitud de modelo de utilida
Dispositif de protection oculaire contre les infections destiné à être placé sur les oculaires d'un appareil de microscopie
[ES] Dispositivo (1) de protección ocular ante infecciones destinado a ser colocado en los oculares (12) de un equipo de microscopía (2), donde dicho dispositivo (1) comprende un cilindro abierto (3) destinado a cubrir el ocular (12) del equipo de microscopía (2), dicho cilindro abierto (3) provisto de una porción proximal (4), una porción distal (5), una porción interior (6) y una porción exterior (7), donde la porción proximal (4) está provista de un anillo interior (8) y la porción interior (6) comprende al menos una primera muesca (9) que ejerce de tope con el ocular (12) y está destinada a sujetar una lámina transparente (11) intercambiable introducida en la porción proximal (4) dentro del cilindro abierto (3) entre el anillo interior (8) y la primera muesca (9), de manera que, permite el uso individual y la protección personal ante cualquier equipo de microscopía de una forma eficaz y práctica.[EN] Disclosed is a device (1) for protection against eye infections, which is intended to be placed on eyepieces (12) of a microscopy device (2), wherein the device (1) comprises an open cylinder (3) intended to cover the eyepiece (12) of the microscopy device (2), the open cylinder (3) being provided with a proximal portion (4), a distal portion (5), an internal portion (6) and an external portion (7). According to the invention, the proximal portion (4) is provided with an internal ring (8), and the internal portion (6) comprises at least a first notch (9) that acts as a stop against the eyepiece (12) and which is intended to hold an interchangeable transparent sheet (11) placed on the proximal portion (4) inside the open cylinder (3), between the internal ring (8) and the first notch (9), allowing individual use and personal protection against any microscopy device in an effective and practical manner.[FR] La présente invention concerne un dispositif (1) de protection oculaire contre les infections destiné à être placé sur les oculaires (12) d'un appareil de microscopie (2), lequel dispositif (1) comprend un cylindre ouvert (3) destiné à couvrir l'oculaire (12) de l'appareil de microscopie (2), ledit cylindre ouvert (3) pourvu d'une partie proximale (4), d'une partie distale (5), d'une partie intérieure (6) et d'une partie extérieure (7), laquelle partie proximale (4) est pourvue d'un anneau intérieur (8) et la partie intérieure (6) comprend au moins une première striure (9) qui sert de butée avec l'oculaire (12) et est destinée à fixer une lamelle transparente (11) interchangeable introduite dans la partie proximale (4) dans le cylindre ouvert (3) entre l'anneau intérieur (8) et la première striure (9), de sorte qu'elle permet l'utilisation individuelle et la protection personnelle de n'importe quel appareil de microscopie de manière efficace et pratique.NoConsejo Superior de Investigaciones Científicas (CSIC), Universidad Miguel Hernández de ElcheA1 Solicitud de patente con informe sobre el estado de la técnic
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