Properties of Soils and Plants Uptake within the Vicinity of Selected Automobile Workshops in Ile-Ife Southwestern, Nigeria

Backyard farming is becoming popular among the auto mechanics near their workshops where spent engine oil and carcass of vehicles are continuously dumped in Nigeria. The properties of soil and maize plants sampled from the vicinity of selected auto mechanic workshops in Ile-Ife, Nigeria were investigated. The results showed that heavy metal contents in the soils from the sampled sites were (range, mg kg-1) Fe 1238.12 to 1564.25, Zn 18.10 to 24.75, Pb 1.21 to 3.43 and Hg 0.48 to 0.74. These values were significantly (P< 0.05) higher than the control (non auto mechanic site) with Fe 37.50, Zn 0.70, Pb 0.15 and Hg 0.13 mg kg-1. Also, these soil parameters reduced in values in the sub-soil. The mean concentrations of heavy metals (Fe, Zn, Pb and Hg) in maize plants were significantly (P < 0.05) higher while N and P were significantly (P < 0.05) lower in those from the experimental sites within the vicinity of automobile workshops than in the control. Higher accumulation of these heavy metals was obtained in soil and shoots of maize from older workshops than in the younger ones. The study therefore concluded that edible crops, particularly the phytoplants should not be cultivated on polluted soils as this may pose a threat to human health, if the heavy metals enter the food chain.Keywords: Backyard farming, automobile, spent engine oil, carcass of vehicle, plant uptake, phytoplant

Novel fluorescent amphiphilic poly(allylamine) and their supramacromolecular self-assemblies in aqueous media.

Fluorescent amphiphilic polymers were produced by grafting different types and levels of hydrophobic pendant groups with intrinsic fluorescent properties (fluorenylmethoxy carbonyl (Fmoc), dimethylamino-1-naphthalenesulfonyl (Dansyl), and naphthalene (Naphth) to a water soluble homopolymer backbone, polyallylamine (PAA). Non-fluorescent hydrophobic pendant group (cholesteryl moieties) were also grafted onto PAA. The polymers were characterized with elemental analysis, NMR and FTIR spectroscopy. All polymers formed self-assemblies by probe sonication in water with sizes ranging from 120 to 199 nm and TEM images showed the presence of spherical particles.Peer reviewe

The Study on the Entrapment Efficiency and In Vitro Release of Puerarin Submicron Emulsion

The entrapment efficiency (EE) and release in vitro are very important physicochemical characteristics of puerarin submicron emulsion (SME). In this paper, the performance of ultrafiltration (UF), ultracentrifugation (UC), and microdialysis (MD) for determining the EE of SME were evaluated, respectively. The release study in vitro of puerarin from SME was studied by using MD and pressure UF technology. The EE of SME was 86.5%, 72.8%, and 55.8% as determined by MD, UF, and UC, respectively. MD was not suitable for EE measurements of puerarin submicron oil droplet, which could only determine the total EE of submicron oil droplet and liposomes micelles, but it could be applied to determine the amount of free drug in SMEs. Although UC was the fastest and simplest to use, its results were the least reliable. UF was still the relatively accurate method for EE determination of puerarin SME. The release of puerarin SME could be evaluated by using MD and pressure UF, but MD seemed to be more suitable for the release study of puerarin emulsion. The drug release from puerarin SME at three drug concentrations was initially rapid, but reached a plateau value within 30 min. Drug release of puerarin from the SME occurred via burst release

New methods for improved characterization of silica nanoparticle-based drug delivery systems

The incorporation of silica nanoparticles into drug delivery vehicles, and other nanotech platforms, has experienced rapid and significant growth over the past decade. However, as these nanoparticle-based systems become more and more complex, the methods used to analyze these systems have evolved at a comparatively much slower pace, resulting in the need for researchers to expand their toolbox and devise new strategies to characterize these materials. This article describes how X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF-SIMS) were recently employed in the analysis of two separate drug delivery systems which contain organic compounds covalently attached to the surfaces of silica nanoparticles. These techniques provided a deluge of qualitative and quantitative information about these drug delivery systems, and have several clear advantages over more common characterization procedures such as Fourier transform infrared spectroscopy (FT-IR) and solid state nuclear magnetic resonance (SSNMR). Thus, XPS and ToF-SIMS should be an integral component of the standard characterization protocol for any nanoparticle-based assemblies particularly silica-based drug delivery systems-as this field of research continues to develop