49 research outputs found

    Hjemløshed i Grønland

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    HUBUNGAN ANTARA KOMITMEN BERPACARAN DENGAN KUALITAS PERSAHABATAN PADA REMAJA AKHIR DI UNIVERSITAS PENDIDIKAN INDONESIA

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    Penelitian ini memiliki beberapa tujuan, yaitu untuk mengetahui (1) gambaran komitmen berpacaran, (2) gambaran kualitas persahabatan, (3) hubungan antara komitmen berpacaran dengan kualitas persahabatan pada remaja akhir di Universitas Pendidikan Indonesia (UPI). Responden pada penelitian ini ialah mahasiswa di UPI yang berada pada usia remaja akhir yang memiliki pasangan (pacar) dan juga teman dekat (sahabat). Terdapat 200 orang responden sesuai kriteria yang telah ditentukan dalam penelitian ini. Penelitian ini menggunakan metode kuantitatif dan menggunakan teknik purposive sampling. Pengumpulan data dilakukan melalui penyebaran kuesioner dengan memanfaatkan aplikasi google docs. Kuesioner berisikan skala komitmen berpacaran yang peneliti adaptasi dan modifikasi dari Commitment Measurenment milik Rusbult (1983) dan skala kualitas persahabatan yang juga peneliti adaptasi dan modifikasi dari Friendship Quality Scale (FQS) milik Bukowski, Hoza, dan Bovin (Ponti, dkk, 2010). Data yang diperoleh dianalisis menggunakan teknik korelasi Spearman Rho. Hasil penelitian menunjukkan (1) remaja akhir di UPI memiliki komitmen berpacaran yang cenderung rendah yaitu sebanyak 41% dari 200 orang responden, (2) remaja akhir di UPI memiliki kualitas persahabatan yang cenderung rendah yaitu sebanyak 36,5% dari 200 orang responden, dan (3) terdapat hubungan yang antara komitmen berpacaran dengan kualitas persahabatan pada remaja akhir di Universitas Pendidikan Indonesia.---------This study aims to describe (1) the image of commitment dating (2) the big picture of quality of friendship, and (3) relationship between Commitment Dating with the quality of friendship late adolescence at Indonesia University of Education (UPI). Responders of this study are late adolescence at Indonesia University of Education who are in commitment relationship and having close friends. There are around 200 people with the appropriate criteria have been determined in this study. This study uses quantitative methods and using purposive sampling technique. Data collected through questionnaires by using google docs app. The questionnaire contains of a commitment dating scale that is adapted by researcher and modification of Commitment Measurenment owned by Rusbult (1983) and so is Quality Scale (FQS) belongs to Bukowski, Hoza, and Bovin (Ponti et al, 2010). Data was analyzed by using Spearman Rho correlation techniques. The result showed that (1) late adolescence of UPI who are in committed relationship that tends to lower as many as 41% of the 200 respondents, (2) late adolescence of UPI have a rather low quality friendships as many as 36.5% of the 200 respondents, and (3) there is a relationship between commitment dating with the quality of friendship in late teens at UPI

    First fabrication of full 3D-detectors at SINTEF

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    International audienceA knowledge of the mechanical properties of bacterial biofilms is required to more fully understand the processes of biofilm formation such as initial adhesion or detachment. The main contribution of this article is to demonstrate the use of homogenization techniques to compute mechanical parameters of Pseudomonas aeruginosa PAO1 biofilms. For this purpose, homogenization techniques are used to analyze freeze substitution electron micrographs of the biofilm cross-sections. The concept of a representative volume element and the study about his representativeness allows us to determine the optimal size in order to analyze these biofilm images. Results demonstrate significant heterogeneities with respect to stiffness and these can be explained by varying cell density distribution throughout the bacterial biofilms. These stiffness variations lead to different mechanical properties along the height of the biofilm. Moreover, a numerical shear stress test shows the impact of these heterogeneities on the detachment process. Several modes of detachment are highlighted according to the local strain energy in the different parts of the biofilm. Knowing where, and how, a biofilm may detach will allow better prediction of accumulation and biomass detachment

    Characterization of boron-coated silicon sensors for thermal neutron detection

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    Silicon neutron detectors can operate at low voltage and come with ease of fabrication and the possibility of integration of readout electronics and thus are attractive from an application point of view. In this paper, we have studied thermal neutron capture by silicon diodes coated with boron carbide (B4C). One of the surfaces of the diodes was covered with either natural B4C (B4C) or with enriched B4C (B4C). We have investigated: (a) the effect of increase in the sensitive area of the surface of the diode covered with B4C on the neutron detection efficiency and (b) the effect of enrichment of 10B in B4C. The difference in 10B in B4C (16 at.% in the deposited film) and B4C ( 79 at.% in the deposited film) leads to about three times increase in detection efficiency of the same detector. For the given experimental conditions, we do not observe a direct relationship between increase in the surface area and the detection efficiency. Energy spectra obtained by Geant4 simulations support the experimental observation of finding no direct relation between increase in the surface area and the detection efficiency.publishedVersio

    Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

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    OBJECTIVE: Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired β-cell function, raised glucose levels, insulin resistance, and type 2 diabetes (T2D). Studies of the insulin processing pathway could provide new insights about T2D pathophysiology. RESEARCH DESIGN AND METHODS: We have conducted a meta-analysis of genome-wide association tests of ∼2.5 million genotyped or imputed single nucleotide polymorphisms (SNPs) and fasting proinsulin levels in 10,701 nondiabetic adults of European ancestry, with follow-up of 23 loci in up to 16,378 individuals, using additive genetic models adjusted for age, sex, fasting insulin, and study-specific covariates. RESULTS: Nine SNPs at eight loci were associated with proinsulin levels (P < 5 × 10(-8)). Two loci (LARP6 and SGSM2) have not been previously related to metabolic traits, one (MADD) has been associated with fasting glucose, one (PCSK1) has been implicated in obesity, and four (TCF7L2, SLC30A8, VPS13C/C2CD4A/B, and ARAP1, formerly CENTD2) increase T2D risk. The proinsulin-raising allele of ARAP1 was associated with a lower fasting glucose (P = 1.7 × 10(-4)), improved β-cell function (P = 1.1 × 10(-5)), and lower risk of T2D (odds ratio 0.88; P = 7.8 × 10(-6)). Notably, PCSK1 encodes the protein prohormone convertase 1/3, the first enzyme in the insulin processing pathway. A genotype score composed of the nine proinsulin-raising alleles was not associated with coronary disease in two large case-control datasets. CONCLUSIONS: We have identified nine genetic variants associated with fasting proinsulin. Our findings illuminate the biology underlying glucose homeostasis and T2D development in humans and argue against a direct role of proinsulin in coronary artery disease pathogenesis
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