Exploring Music Genre Classification: Algorithm Analysis and Deployment Architecture

Music genre classification has become increasingly critical with the advent of various streaming applications. Nowadays, we find it impossible to imagine using the artist's name and song title to search for music in a sophisticated music app. It is always difficult to classify music correctly because the information linked to music, such as region, artist, album, or non-album, is so variable. This paper presents a study on music genre classification using a combination of Digital Signal Processing (DSP) and Deep Learning (DL) techniques. A novel algorithm is proposed that utilizes both DSP and DL methods to extract relevant features from audio signals and classify them into various genres. The algorithm was tested on the GTZAN dataset and achieved high accuracy. An end-to-end deployment architecture is also proposed for integration into music-related applications. The performance of the algorithm is analyzed and future directions for improvement are discussed. The proposed DSP and DL-based music genre classification algorithm and deployment architecture demonstrate a promising approach for music genre classification

Design of a Low-Power High-Gain Bio-Medical Operational Amplifier in 65nm Technology using gm/ID Methodology

Operational Amplifiers (Op-Amps) play a crucial role in the field of biomedical engineering, as they enable signal amplification and processing in various medical devices. With the increasing demand for portable and low-power biomedical devices, designing Op-Amps specifically tailored for such applications is essential. In response to this need, a low-power high-gain Op-Amp designed for biomedical applications using TSMC 65nm technology has been proposed. This Op-Amp incorporates a two-stage miller compensated topology, which is well-known for its superior performance in gain, gain bandwidth product and power consumption. The proposed Op-Amp contributes to the field of biomedical engineering by offering a tailored solution that enhances signal processing capabilities, enables accurate data acquisition, and improves overall efficiency in healthcare systems. The design methodology and simulation results presented in this paper provide insights into the performance and potential impact of the Op-Amp in advancing biomedical devices and systems

Jet modification in absence of QGP-medium: the role of multiparton interactions and color reconnection

Recent studies of high-multiplicity events in small collision systems (proton-proton and proton-lead) have drawn research interest towards the possibility of the formation of partonic medium in such systems. One of the important consequences of the formation of dense partonic medium is quenching of high-momentum final-state particles resulting in several experimental observations such as suppression in nuclear modification factor $R_{\rm AA}$, modification of jet shape observable $\rho(r)$, etc. In this work, we study $\rho(r)$ for inclusive charged-particle jets in proton-proton (pp) collisions at $\sqrt{s}$ = 13 TeV using PYTHIA 8 Monash 2013 Monte Carlo simulation and show that the color reconnection (CR) and multiparton interaction (MPI) mechanisms in PYTHIA 8 can also lead to a significant amount of modification of $\rho(r)$ in high-multiplicity events compared to minimum bias events for 10 $<p_{\rm T,\,jet}^{\rm ch}<$ 20 GeV/$c$. The enhanced gluonic contribution in high-multiplicity events is also found to play a role in the observed modification of $\rho(r)$. We notice a direct connection between the number of MPIs and the amount of modification in $\rho(r)$ - the larger the number of MPIs, the larger the amount of modification of $\rho(r)$.Comment: 14 pages, 7 figures, 1 tabl

Pierwotny śródczaszkowy bazaloidalny rak płaskonabłonkowy

Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from malignant transformation of dysembryogenetic lesions such as epidermoid and dermoid cysts. Intracranial squamous cell neoplasm arising de novo is even rarer and has been reported in only four patients to date. We herein describe a case of primary intracranial squamous cell carcinoma arising de novo in the right frontal lobe in a 35-year-old woman treated with a combination of surgery and postoperative conformal radiation. We have also shed light on the biology and the therapeutic options of this enigmatic tumour.Pierwotny śródczaszkowy rak płaskonabłonkowy jest wyjątkową rzadkością i w większości przypadków rozwija się w wyniku zezłośliwienia zmian o charakterze dysembriogenetycznym, np. torbieli naskórkowej lub skórzastej. Śródczaszkowy rak płaskonabłonkowy powstały de novo jest jeszcze rzadszy – dotąd opisano 4 takie przypadki. W niniejszej pracy przedstawiono przypadek nowotworu powstałego de novo w prawym płacie czołowym u 35-letniej chorej, którą z tego powodu poddano leczeniu chirurgicznemu i pooperacyjnej radioterapii konformalnej. Podano również informacje na temat biologii i możliwości leczenia tego zagadkowego guza

Development of a water-based cooling system for the Muon Chamber detector system of the CBM experiment

A water-based cooling system is being investigated to meet the cooling requirement of the Gas Electron Multiplier (GEM) based Muon Chamber (MuCh) detector system of the Compressed Baryonic Matter (CBM) experiment at GSI, Germany. The system is based on circulating cold water through the channels inside an aluminium plate. The aluminium plate is attached to a GEM chamber. A feasibility study is conducted on one small and two real-size prototype cooling plates. A microcontroller based unit has been built and integrated into the system to achieve automatic control and monitoring of temperature on plate surface. The real-size prototypes have been used in a test beam experiment at the CERN SPS (Super Proton Synchrotron) with the lead beam on a lead target. A setup using three prototype modules has been prepared in the lab for testing in a simulated real life environment. This paper discusses the working principle, mechanical design, fabrication, and test results of the cooling prototypes in detail.Comment: 8 pages, 12 figures, 2 table

Prognostic Stratification of GBMs Using Combinatorial Assessment of IDH1 Mutation, MGMT Promoter Methylation, and TERT Mutation Status: Experience from a Tertiary Care Center in India

AbstractThis study aims to establish the best and simplified panel of molecular markers for prognostic stratification of glioblastomas (GBMs). One hundred fourteen cases of GBMs were studied for IDH1, TP53, and TERT mutation by Sanger sequencing; EGFR and PDGFRA amplification by fluorescence in situ hybridization; NF1expression by quantitative real time polymerase chain reaction (qRT-PCR); and MGMT promoter methylation by methylation-specific PCR. IDH1 mutant cases had significantly longer progression-free survival (PFS) and overall survival (OS) as compared to IDH1 wild-type cases. Combinatorial assessment of MGMT and TERT emerged as independent prognostic markers, especially in the IDH1 wild-type GBMs. Thus, within the IDH1 wild-type group, cases with only MGMT methylation (group 1) had the best outcome (median PFS: 83.3 weeks; OS: not reached), whereas GBMs with only TERT mutation (group 3) had the worst outcome (PFS: 19.7 weeks; OS: 32.8 weeks). Cases with both or none of these alterations (group 2) had intermediate prognosis (PFS: 47.6 weeks; OS: 89.2 weeks). Majority of the IDH1 mutant GBMs belonged to group 1 (75%), whereas only 18.7% and 6.2% showed group 2 and 3 signatures, respectively. Interestingly, none of the other genetic alterations were significantly associated with survival in IDH1 mutant or wild-type GBMs.Based on above findings, we recommend assessment of three markers, viz., IDH1, MGMT, and TERT, for GBM prognostication in routine practice. We show for the first time that IDH1 wild-type GBMs which constitute majority of the GBMs can be effectively stratified into three distinct prognostic subgroups based on MGMT and TERT status, irrespective of other genetic alterations

Challenges in QCD matter physics - The Compressed Baryonic Matter experiment at FAIR

Substantial experimental and theoretical efforts worldwide are devoted to explore the phase diagram of strongly interacting matter. At LHC and top RHIC energies, QCD matter is studied at very high temperatures and nearly vanishing net-baryon densities. There is evidence that a Quark-Gluon-Plasma (QGP) was created at experiments at RHIC and LHC. The transition from the QGP back to the hadron gas is found to be a smooth cross over. For larger net-baryon densities and lower temperatures, it is expected that the QCD phase diagram exhibits a rich structure, such as a first-order phase transition between hadronic and partonic matter which terminates in a critical point, or exotic phases like quarkyonic matter. The discovery of these landmarks would be a breakthrough in our understanding of the strong interaction and is therefore in the focus of various high-energy heavy-ion research programs. The Compressed Baryonic Matter (CBM) experiment at FAIR will play a unique role in the exploration of the QCD phase diagram in the region of high net-baryon densities, because it is designed to run at unprecedented interaction rates. High-rate operation is the key prerequisite for high-precision measurements of multi-differential observables and of rare diagnostic probes which are sensitive to the dense phase of the nuclear fireball. The goal of the CBM experiment at SIS100 (sqrt(s_NN) = 2.7 - 4.9 GeV) is to discover fundamental properties of QCD matter: the phase structure at large baryon-chemical potentials (mu_B > 500 MeV), effects of chiral symmetry, and the equation-of-state at high density as it is expected to occur in the core of neutron stars. In this article, we review the motivation for and the physics programme of CBM, including activities before the start of data taking in 2022, in the context of the worldwide efforts to explore high-density QCD matter.Comment: 15 pages, 11 figures. Published in European Physical Journal

Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions

We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe

Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe