14 research outputs found
Searching for pathways involving dressed states in optimal control theory
Selective population of dressed states has been proposed as an alternative control
pathway in molecular reaction dynamics [Wollenhaupt et al., J. Photochem.
Photobiol. A: Chem., 2006, 180, 248]. In this article we investigate if, and under
which conditions, this strong field pathway is included in the search space of
optimal control theory. For our calculations we used the proposed example of the
potassium dimer, in which the different target states can be reached via dressed
states by resonant transition. Especially, we investigate whether the optimization
algorithm is able to find the route involving the dressed states although the target
state lies out of resonance in the bare state picture
Optimally shaped terahertz pulses for phase retrieval in a Rydberg atom data register
We employ Optimal Control Theory to discover an efficient information
retrieval algorithm that can be performed on a Rydberg atom data register using
a shaped terahertz pulse. The register is a Rydberg wave packet with one
consituent orbital phase-reversed from the others (the ``marked bit''). The
terahertz pulse that performs the decoding algorithm does so by by driving
electron probability density into the marked orbital. Its shape is calculated
by modifying the target of an optimal control problem so that it represents the
direct product of all correct solutions to the algorithm.Comment: 6 pages, 3 figure
Optimal control theory - closing the gap between theory and experiment
Optimal control theory and optimal control experiments are state-of-the-art tools to control quantum systems. Both methods have been demonstrated successfully for numerous applications in molecular physics, chemistry and biology. Modulated light pulses could be realized, driving these various control processes. Next to the control efficiency, a key issue is the understanding of the control mechanism. An obvious way is to seek support from theory. However, the underlying search strategies in theory and experiment towards the optimal laser field differ. While the optimal control theory operates in the time domain, optimal control experiments optimize the laser fields in the frequency domain. This also implies that both search procedures experience a different bias and follow different pathways on the search landscape. In this perspective we review our recent developments in optimal control theory and their applications. Especially, we focus on approaches, which close the gap between theory and experiment. To this extent we followed two ways. One uses sophisticated optimization algorithms, which enhance the capabilities of optimal control experiments. The other is to extend and modify the optimal control theory formalism in order to mimic the experimental conditions
Cardioembolic Stroke in Atrial Fibrillation-Rationale for Preventive Closure of the Left Atrial Appendage
Atrial fibrillation is the most common cardiac arrhythmias, and a major cause of morbidity and mortality due to cardioembolic stroke. The left atrial appendage is the major site of thrombus formation in non-valvular atrial fibrillation. Loss of atrial systole in atrial fibrillation and increased relative risk of associated stroke point strongly toward a role for stasis of blood in left atrial thrombosis, although thrombus formation is multifactorial, and much more than blood flow irregularities are implicated. Oral anticoagulation with vitamin-K-antagonists is currently the most effective prophylaxis for stroke in atrial fibrillation. Unfortunately, this treatment is often contraindicated, particularly in the elderly, in whom risk of stroke is high. Moreover, given the risk of major bleeding, there is reason to be skeptical of the net benefit when warfarin is used in those patients. This work reviews the pathophysiology of cardioembolic stroke and critically spotlights the current status of preventive anticoagulation therapy. Various techniques to exclude the left atrial appendage from circulation were discussed as a considerable alternative for stroke prophylaxis