Políticas de Desobediência: Indisciplina e violência ou resistência?

This article presents a study that focuses on the processes of marginalization and criminalization of youth, analyzing their effects on the production of subjectivity of the young people affected by them. The research uses as a methodology conversation with young people aged 13 to 17 enrolled in public schools in the city of Rio de Janeiro, from the insertion of one of the authors as a psychologist of said network. It is worth noting that most of the clientele of such schools are poor, black and community dwellers. The meetings of the talk wheels put on the students' life experiences that are criminalized by social practices and speeches, which seem to be reiterated by the schools. The purpose of the research is to reflect on how these students experience the processes of marginalization and criminalization in which they are directly involved, how these experiences are present in their speeches and how they reverberate in the production of their subjectivities.El presente artículo trae el recorte de un estudio que tiene como tema los procesos de marginación y criminalización de la juventud, poniendo en análisis sus efectos para la producción de subjetividad de los jóvenes afectados por ellos. La investigación utiliza como metodología, ruedas de conversación con jóvenes de 13 a 17 años matriculados en escuelas públicas del municipio de Rio de Janeiro, a partir de la inserción de una de las autoras como psicóloga de dicha red. Se destaca el hecho de que la mayoría de la clientela de tales escuelas está compuesta por jóvenes pobres, negros y moradores de comunidades. Los encuentros de las ruedas de conversación ponen en escena experiencias de vida de los alumnos que vienen a ser criminalizadas por prácticas y discursos sociales, y que parecen reiterados por las escuelas. El objetivo de la investigación es reflexionar sobre cómo estos alumnos vivencian los procesos de marginación y criminalización en que están directamente implicados, como tales experiencias se presentifican en sus palabras y cómo reverberan en la producción de sus subjetividades.O presente artigo traz o recorte de um estudo que tem como tema os processos de marginalização e criminalização da juventude, pondo em análise seus efeitos para a produção de subjetividade dos jovens por eles afetados. A pesquisa utiliza como metodologia, rodas de conversa com jovens de 13 a 17 anos matriculados em escolas públicas do município do Rio de Janeiro, a partir da inserção de uma das autoras como psicóloga da referida rede. Destaca-se o fato da maior parte da clientela de tais escolas ser composta por jovens pobres, negros e moradores de comunidades. Os encontros das rodas de conversa põem em cena experiências de vida dos alunos que vem a ser criminalizadas por práticas e discursos sociais, e que parecem reiterados pelas escolas. O objetivo da pesquisa é refletir sobre como estes alunos vivenciam os processos de marginalização e criminalização no qual estão diretamente implicados, como tais experiências se presentificam em suas falas e como reverberam na produção de suas subjetividades.

Palladium nanoparticles on modified cellulose as a novel catalyst for low temperature gas reactions

Palladium was incorporated into carboxymethylated cellulose fibers as a support, thereby becoming an efficient and stable catalyst for low temperature gas phase reaction. Thus, NO was used as test molecule of Greenhouse Gas to be catalytically reduced with hydrogen on an eco-friendly sustainable material containing palladium as the active site. Prior to the catalytic test, the catalysts were reduced with glucose as an eco-friendly reagent. The material characterization was performed by SEM–EDS, XRD, LRS, TGA and FTIR. The catalytic results showed that at 170 °C, NO conversion was 100% with a selectivity of 70% to nitrogen. While NOX species were completely converted into N2 at temperatures higher than 180 °C. The starting commercial dissolving pulp was also studied, but its performance resulted lower than the ones of functionalized fibers. The use of this strategy, i.e., the functionalization of cellulose fibers followed by in-situ formation of metallic nanoparticles, can be further applied for the design of a wide range of materials with interesting applications for gas and liquid phase reactions under mild conditions.Fil: Gioria, Esteban Gaston. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera". Universidad Nacional del Litoral. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera"; ArgentinaFil: Signorini, Chiara. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera". Universidad Nacional del Litoral. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera"; ArgentinaFil: Taleb, María Claudia. Universidad Nacional del Litoral; ArgentinaFil: Thomas, Arne. Technishe Universitat Berlin; AlemaniaFil: Mihályi, Magdolna R.. No especifíca;Fil: Gutierrez, Laura Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera". Universidad Nacional del Litoral. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera"; Argentin

Adiponectin gene polymorphisms and their effect on the risk of myocardial infarction and type 2 diabetes: an association study in an Italian population.

Objective: While many studies have shown an association between the gene coding for adiponectin (ADIPOQ) and adiponectin levels, much more controversy surrounds its association with metabolic traits such as insulin resistance, obesity and type 2 diabetes. Furthermore, very few studies have looked into the relations between ADIPOQ variants and risk of cardiovascular disease. The present study assessed the influence of four common ADIPOQ Single Nucleotide Polymorphisms (SNPs), rs17300539 (-11391G→A), rs266729 (-11377C→G), rs2241766 (+45T→G) and rs1501299 (+276G→T) on the risk of myocardial infarction and type 2 diabetes. Methods and Results: A large genetic association case-control study was conducted in 2008 Italians, including patients with myocardial infarction, type 2 diabetes, or both, and a reference group of healthy controls. Homozygotes TT for the rs1501299 (+276) had half the risk of either myocardial infarction alone or in association with type 2 diabetes when compared to the carriers of the G allele (OR = 0.58, p =0.01, and OR = 0.55, p =0.006 respectively). SNPs rs17300539 (-11391), rs266729 (-11377) and rs2241766 (+45) showed no significant association with any of the three case groups. Conclusions: These results suggest that homozygotes TT for the adiponectin polymorphism rs1501299 (+276) are protected from the risk of myocardial infarction

The complex globular cluster system of the S0 galaxy NGC 4382 in the outskirts of the Virgo Cluster

NGC 4382 is a merger-remnant galaxy that has been classified as morphological type E2, S0, and even Sa. In this work, we performed a photometric and spectroscopic analysis of the globular cluster (GC) system of this peculiar galaxy in order to provide additional information about its history. We used a combination of photometric data in different filters, and multiobject and long-slit spectroscopic data obtained using the Gemini/GMOS instrument. The photometric analysis of the GC system, using the Gaussian Mixture Model algorithm in the colour plane, reveals a complex colour distribution within Rgal < 5 arcmin (26.1 kpc), showing four different groups: the typical blue and red subpopulations, a group with intermediate colours, and the fourth group towards even redder colours. From the spectroscopic analysis of 47 GCs, confirmed members of NGC 4382 based on radial velocities, we verified 3 of the 4 photometric groups from the analysis of their stellar populations using the ULySS code. NGC 4382 presents the classic blue (10.4 ± 2.8 Gyr, [Fe/H] = −1.48 ± 0.18 dex), and red (12.1 ± 2.3 Gyr, [Fe/H] = −0.64 ± 0.26 dex) GCs formed earlier in the lifetime of the galaxy, and a third group of young GCs (2.2 ± 0.9 Gyr; [Fe/H] = −0.05 ± 0.28 dex). Finally, analysis of long-slit data of the galaxy reveals a luminosity-weighted mean age for the stellar population of ∼2.7 Gyr, and an increasing metallicity from [Fe/H] = −0.1 to +0.2 dex in Rgal < 10 arcsec (0.87 kpc). These values, and other morphological signatures in the galaxy, are in good agreement with the younger group of GCs, indicating a common origin as a result of a recent merger

Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population

<p>Abstract</p> <p>Background</p> <p>A genomic region on chromosome 9p21 has been identified as closely associated with increased susceptibility to coronary artery disease (CAD) and to type 2 diabetes (T2D) although the evidence suggests that the genetic variants within chromosome 9p21 that contribute to CAD are different from those that contribute to T2D.</p> <p>We carried out an association case-control study in an Italian population to test the association between two single nucleotide polymorphisms (SNPs) on the 9p21 locus, rs2891168 and rs10811661, previously reported by the PROCARDIS study, and respectively myocardial infarction (MI) and T2D. Our aim was to confirm the previous findings on a larger sample and to verify the independence of their susceptibility effects: rs2891168 associated with MI but not with T2D and rs10811661 associated with T2D but not with MI.</p> <p>Methods</p> <p>Genomic DNA samples of 2407 Italians with T2D (602 patients), who had had a recent MI (600), or had both diseases (600) and healthy controls (605) were genotyped for the two SNPs. The genotypes were determined by allelic discrimination using a fluorescent-based TaqMan assay.</p> <p>Results</p> <p>SNP rs2891168 was associated with MI, but not with T2D and the G-allele odds ratio (OR) was 1.20 (95% CI 1.02-1.41); SNP rs10811661 was associated with T2D, but not with MI, and the T-allele OR was 1.27 (95% CI 1.04-1.55). ORs estimates from the present study and the PROCARDIS study were pooled and confirmed the previous findings, with greater precision.</p> <p>Conclusions</p> <p>Our replication study showed that rs2891168 and rs10811661 are independently associated respectively with MI and T2D in an Italian population. Pooling our results with those reported by the PROCARDIS group, we also obtained a significant result of association with diabetes for rs10811661 in the European population.</p

The state of the Martian climate

60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes

Evaluación de riesgos de quesos artesanales elaborados con leche caprina

El Ministerio de Agroindustria Secretaría de Agricultura, Ganadería y Pesca Dirección Nacional Láctea solicitó a la Red de Seguridad Alimentaria del CONICET (RSA-CONICET) la realización de una evaluación de riesgos de carácter sanitario que involucre a los pequeños productores que transforman su propia leche o la de sus vecinos en diferentes tipos de productos lácteos (preferentemente quesos).El Ministerio de Agroindustria Secretaría de Agricultura, Ganadería y Pesca Dirección Nacional Láctea solicitó a la Red de Seguridad Alimentaria del CONICET (RSA-CONICET) la realización de una evaluación de riesgos de la producción artesanal de quesos a partir de leche caprina (para establecimientos de baja escala). La elaboración de quesos artesanales en Argentina se desarrolla en la mayoría de los establecimientos lecheros como un recurso económico complementario. Estos productos no se hallan contemplados en la legislación vigente y se elaboran con metodologías que se transmiten familiarmente en forma oral utilizando, en la mayoría de los casos, leche entera cruda de cabra. La venta de quesos se produce en un mercado informal sin ser sometidos a una maduración completa y evaluación microbiológica previa a su destino final, el consumidor. Con tal motivo, la RSA-CONICET conformó un grupo de trabajo ad hoc de tipo multidisciplinario constituido por investigadores con experiencia en diferentes aspectos relacionados al proceso de producción de quesos, microbiología y tecnología de alimentos, calidad e inocuidad de leche y productos lácteos, epidemiología, entre otros aspectos. El objetivo de este grupo ad hoc fue evaluar cuantitativamente la probabilidad que tiene una persona en nuestro país de padecer una enfermedad causada por S. aureus y E. coli (dos microorganismos normalmente asociados al consumo de productos lácteos en general y quesos en particular) debido al consumo de quesos artesanales elaborados a partir de leche bovina. Se estableció que la evaluación de riesgos seguiría las cuatro etapas características de este proceso: identificación del peligro, evaluación de la exposición, caracterización del peligro y caracterización del riesgo.Fil: del Castillo, Lourdes Leonor. Instituto Nacional de Tecnologia Agropecuaria. Centro Regional Salta-jujuy. Estacion Experimental Agropecuaria Salta. Agencia de Extension Rural Cafayate.; ArgentinaFil: Mendez, Carla Rebeca. Instituto Nacional de Tecnologia Agropecuaria. Centro Regional Catamarca-la Rioja. Estacion Experimental Agropecuaria la Rioja. Agencia de Extension Rural Chepes.; ArgentinaFil: Dome, Claudia Beatriz. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias. Área Ciencia de Alimentos; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce; ArgentinaFil: Cortez, Héctor Sergio. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Salta. Estación Experimental Agropecuaria Salta; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; ArgentinaFil: Rubel, Irene Albertina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ingeniería; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Agronomía; ArgentinaFil: Mignino, Lorena Arminda. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; ArgentinaFil: Signorini Porchietto, Marcelo Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; ArgentinaFil: Nuñez de Kairúz, Martha Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Chavez Clemente, Mónica Silvina. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Salta-Jujuy. Estación Experimental Agropecuaria Salta; ArgentinaFil: Torres, Nancy Alejandra. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Salta-Jujuy. Estación Experimental Agropecuaria Salta; ArgentinaFil: Orosco, Silvia Marisol. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Salta-Jujuy. Estación Experimental Agropecuaria Salta; ArgentinaFil: Saldaño, Silvina. Instituto Nacional de Tecnologia Agropecuaria. Centro Regional Tucuman-santiago del Estero. Estacion Experimental.agropecuaria Famailla. Agencia de Extension Rural Simoca.; Argentin

Diagnosis of prostate cancer with magnetic resonance imaging in men treated with 5-alpha-reductase inhibitors

Purpose The primary aim of this study was to evaluate if exposure to 5-alpha-reductase inhibitors (5-ARIs) modifies the effect of MRI for the diagnosis of clinically significant Prostate Cancer (csPCa) (ISUP Gleason grade &gt;= 2).Methods This study is a multicenter cohort study including patients undergoing prostate biopsy and MRI at 24 institutions between 2013 and 2022. Multivariable analysis predicting csPCa with an interaction term between 5-ARIs and PIRADS score was performed. Sensitivity, specificity, and negative (NPV) and positive (PPV) predictive values of MRI were compared in treated and untreated patients.Results 705 patients (9%) were treated with 5-ARIs [median age 69 years, Interquartile range (IQR): 65, 73; median PSA 6.3 ng/ml, IQR 4.0, 9.0; median prostate volume 53 ml, IQR 40, 72] and 6913 were 5-ARIs naive (age 66 years, IQR 60, 71; PSA 6.5 ng/ml, IQR 4.8, 9.0; prostate volume 50 ml, IQR 37, 65). MRI showed PIRADS 1-2, 3, 4, and 5 lesions in 141 (20%), 158 (22%), 258 (37%), and 148 (21%) patients treated with 5-ARIs, and 878 (13%), 1764 (25%), 2948 (43%), and 1323 (19%) of untreated patients (p &lt; 0.0001). No difference was found in csPCa detection rates, but diagnosis of high-grade PCa (ISUP GG &gt;= 3) was higher in treated patients (23% vs 19%, p = 0.013). We did not find any evidence of interaction between PIRADS score and 5-ARIs exposure in predicting csPCa. Sensitivity, specificity, PPV, and NPV of PIRADS &gt;= 3 were 94%, 29%, 46%, and 88% in treated patients and 96%, 18%, 43%, and 88% in untreated patients, respectively.Conclusions Exposure to 5-ARIs does not affect the association of PIRADS score with csPCa. Higher rates of high-grade PCa were detected in treated patients, but most were clearly visible on MRI as PIRADS 4 and 5 lesions.Trial registration The present study was registered at ClinicalTrials.gov number: NCT05078359