29 research outputs found
The Impact of cold gas accretion above a mass floor on galaxy scaling relations
Using the cosmological baryonic accretion rate and normal star formation
efficiencies, we present a very simple model for star-forming galaxies (SFGs)
that accounts for the mass and redshift dependencies of the SFR-Mass and
Tully-Fisher relations from z=2 to the present. The time evolution follows from
the fact that each modelled galaxy approaches a steady state where the SFR
follows the (net) cold gas accretion rate. The key feature of the model is a
halo mass floor M_{min}~10^{11} below which accretion is quenched in order to
simultaneously account for the observed slopes of the SFR-Mass and
Tully-Fischer relations. The same successes cannot be achieved via a
star-formation threshold (or delay) nor by varying the SF efficiency or the
feedback efficiency. Combined with the mass ceiling for cold accretion due to
virial shock heating, the mass floor M_{min} explains galaxy "downsizing",
where more massive galaxies formed earlier and over a shorter period of time.
It turns out that the model also accounts for the observed galactic baryon and
gas fractions as a function of mass and time, and the cosmic SFR density from
z~6 to z=0, which are all resulting from the mass floor M_{min}. The model
helps to understand that it is the cosmological decline of accretion rate that
drives the decrease of cosmic SFR density between z~2 and z=0 and the rise of
the cosmic SFR density allows us to put a constraint on our main parameter
M_{min}~10^{11} solar masses. Among the physical mechanisms that could be
responsible for the mass floor, we view that photo-ionization feedback (from
first in-situ hot stars) lowering the cooling efficiency is likely to play a
large role.Comment: 19pages, 14 figures, accepted to ApJ, updated reference
Incorporating end-users' voices into the development of an implant for HIV prevention : a discrete choice experiment in South Africa and Zimbabwe
AVAILABILITY OF DATA AND MATERIALS : The datasets used and/or analyzed during the current study are available from
the corresponding author on reasonable request.BACKGROUND : Input from end-users during preclinical phases can support market fit for new HIV prevention technologies.
With several long-acting pre-exposure prophylaxis (PrEP) implants in development, we aimed to understand
young women’s preferences for PrEP implants to inform optimal design.
METHODS : We developed a discrete choice experiment and surveyed 800 young women in Harare, Zimbabwe and
Tshwane, South Africa between September–November 2020. Women aged 18–30 years who were nulliparous, postpartum,
or exchanged sex for money, goods or shelter in prior year were eligible; quotas were set for each subgroup.
The DCE asked participants to choose between two hypothetical implants for HIV prevention in a series of nine
questions. Implants were described by: size, number of rods and insertion sites, duration (6-months, 1-year, 2-years),
flexibility, and biodegradability. Random-parameters logit models estimated preference weights.
RESULTS : Median age was 24 years (interquartile range 21–27). By design, 36% had used contraceptive implants. Duration
of protection was most important feature, with strong preference for a 2-year over 6-month implant. In Zimbabwe,
the number of rods/insertion sites was second most important and half as important as duration. Nonetheless,
to achieve an implant lasting 2-years, 74% were estimated to accept two rods, one in each arm. In South Africa,
preference was for longer, flexible implants that required removal, although each of these attributes were one-third
as important as duration. On average, biodegradability and size did not influence Zimbabwean women’s choices.
Contraceptive implant experience and parity did not influence relative importance of attributes.
CONCLUSIONS : While duration of protection was a prominent attribute shaping women’s choices for PrEP implants,
other characteristics related to discreetness were relevant. Optimizing for longest dosing while also ensuring minimal
detection of implant placement seemed most attractive to potential users.The American people through the United States Agency for International Development (USAID), U.S. President’s Emergency Plan for AIDS Relief as well as the support of the Bill & Melinda Gates Foundation.https://bmcwomenshealth.biomedcentral.comam2024Medical MicrobiologySDG-03:Good heatlh and well-bein
Cuspy No More: How Outflows Affect the Central Dark Matter and Baryon Distribution in Lambda CDM Galaxies
We examine the evolution of the inner dark matter (DM) and baryonic density
profile of a new sample of simulated field galaxies using fully cosmological,
Lambda CDM, high resolution SPH + N-Body simulations. These simulations include
explicit H2 and metal cooling, star formation (SF) and supernovae (SNe) driven
gas outflows. Starting at high redshift, rapid, repeated gas outflows following
bursty SF transfer energy to the DM component and significantly flatten the
originally `cuspy' central DM mass profile of galaxies with present day stellar
masses in the 10^4.5 -- 10^9.8 Msolar range. At z=0, the central slope of the
DM density profile of our galaxies (measured between 0.3 and 0.7 kpc from their
centre) is well fitted by rhoDM propto r^alpha with alpha \simeq -0.5 + 0.35
log_10(Mstar/10^8Msolar) where Mstar is the stellar mass of the galaxy and 4 <
log_10 Mstar < 9.4. These values imply DM profiles flatter than those obtained
in DM--only simulations and in close agreement with those inferred in galaxies
from the THINGS and LITTLE THINGS survey. Only in very small halos, where by
z=0 star formation has converted less than ~ 0.03% of the original baryon
abundance into stars, outflows do not flatten the original cuspy DM profile out
to radii resolved by our simulations. The mass (DM and baryonic) measured
within the inner 500 pc of each simulated galaxy remains nearly constant over
four orders of magnitudes in stellar mass for Mstar 10^9 Msolar. This finding
is consistent with estimates for faint Local Group dwarfs and field galaxies.
These results address one of the outstanding problems faced by the CDM model,
namely the strong discrepancy between the original predictions of cuspy DM
profiles and the shallower central DM distribution observed in galaxies.Comment: MNRAS in press. Accepted version, a few references added. 12 pages.
Animation at http://youtu.be/FbcgEovabDI?hd=
The Beginning and Evolution of the Universe
We review the current standard model for the evolution of the Universe from
an early inflationary epoch to the complex hierarchy of structure seen today.
We summarize and provide key references for the following topics: observations
of the expanding Universe; the hot early Universe and nucleosynthesis; theory
and observations of the cosmic microwave background; Big Bang cosmology;
inflation; dark matter and dark energy; theory of structure formation; the cold
dark matter model; galaxy formation; cosmological simulations; observations of
galaxies, clusters, and quasars; statistical measures of large-scale structure;
and measurement of cosmological parameters. We conclude with discussion of some
open questions in cosmology. This review is designed to provide a graduate
student or other new worker in the field an introduction to the cosmological
literature.Comment: 69 pages. Invited review article for Publications of the Astronomical
Society of the Pacific. Supplementary references, tables, and more concise
PDF file at http://www.physics.drexel.edu/univers
The stellar halo of the Galaxy
Stellar halos may hold some of the best preserved fossils of the formation
history of galaxies. They are a natural product of the merging processes that
probably take place during the assembly of a galaxy, and hence may well be the
most ubiquitous component of galaxies, independently of their Hubble type. This
review focuses on our current understanding of the spatial structure, the
kinematics and chemistry of halo stars in the Milky Way. In recent years, we
have experienced a change in paradigm thanks to the discovery of large amounts
of substructure, especially in the outer halo. I discuss the implications of
the currently available observational constraints and fold them into several
possible formation scenarios. Unraveling the formation of the Galactic halo
will be possible in the near future through a combination of large wide field
photometric and spectroscopic surveys, and especially in the era of Gaia.Comment: 46 pages, 16 figures. References updated and some minor changes.
Full-resolution version available at
http://www.astro.rug.nl/~ahelmi/stellar-halo-review.pd
Damped Lyman Alpha Systems in Galaxy Formation Simulations
We investigate the population of z=3 damped Lyman alpha absorbers (DLAs) in a
recent series of high resolution galaxy formation simulations. The simulations
are of interest because they form at z=0 some of the most realistic disk
galaxies to date. No free parameters are available in our study: these have
been fixed by physical and z=0 observational constraints, and thus our study
provides a genuine consistency test. The precise role of DLAs in galaxy
formation remains in debate, but they provide a number of strong constraints on
the nature of our simulated bound systems at z=3 because of their coupled
information on neutral H I densities, kinematics, metallicity and estimates of
star formation activity.
Our results, without any parameter-tuning, closely match the observed
incidence rate and column density distributions of DLAs. Our simulations are
the first to reproduce the distribution of metallicities (with a median of
Z_{DLA} = Z_{solar}/20) without invoking observationally unsupported mechanisms
such as dust biasing. This is especially encouraging given that these
simulations have previously been shown to have a realistic 0<z<2 stellar
mass-metallicity relation. Additionally, we see a strong positive correlation
between sightline metallicity and low-ion velocity width, the normalization and
slope of which comes close to matching recent observational results. However,
we somewhat underestimate the number of observed high velocity width systems;
the severity of this disagreement is comparable to other recent DLA focused
studies. By z=0 the majority of the z=3 neutral gas forming the DLAs has been
converted into stars, in agreement with rough physical expectations.
[Abridged]Comment: 24 pages, 18 figures, MNRAS in press. Minor update with a few added
details and typographical/grammatical fixes. Movie at
http://www.ast.cam.ac.uk/~app26
MAGICC haloes: confronting simulations with observations of the circumgalactic medium at z=0
We explore the circumgalactic medium (CGM) of two simulated star-forming
galaxies with luminosities L ~ 0.1 and 1 L* generated using the smooth particle
hydrodynamic code GASOLINE. These simulations are part of the Making Galaxies
In a Cosmological Context (MAGICC) program in which the stellar feedback is
tuned to match the stellar mass-halo mass relationship. For comparison, each
galaxy was also simulated using a 'lower feedback' (LF) model which has
strength comparable to other implementations in the literature. The 'MAGICC
feedback' (MF) model has a higher incidence of massive stars and an
approximately two times higher energy input per supernova. Apart from the
low-mass halo using LF, each galaxy exhibits a metal-enriched CGM that extends
to approximately the virial radius. A significant fraction of this gas has been
heated in supernova explosions in the disc and subsequently ejected into the
CGM where it is predicted to give rise to substantial O VI absorption. The
simulations do not yet address the question of what happens to the O VI when
the galaxies stop forming stars. Our models also predict a reservoir of cool H
I clouds that show strong Ly\alpha absorption to several hundred kpc. Comparing
these models to recent surveys with the Hubble Space Telescope, we find that
only the MF models have sufficient O VI and H I gas in the CGM to reproduce the
observed distributions. In separate analyses, these same MF models also show
better agreement with other galaxy observables (e.g. rotation curves, surface
brightness profiles and H I gas distribution). We infer that the CGM is the
dominant reservoir of baryons for galaxy haloes.Comment: 9 pages, 7 figures, submitted MNRAS, comments welcom
The economics of debt clearing mechanisms
We examine the evolution of decentralized clearinghouse mechanisms from the
13th to the 18th century; in particular, we explore the clearing of non- or
limitedtradable debts like bills of exchange. We construct a theoretical model
of these clearinghouse mechanisms, similar to the models in the theoretical
matching literature, and show that specific decentralized multilateral
clearing algorithms known as rescontre, skontrieren or virement des parties
used by merchants were efficient in specific historical contexts. We can
explain both the evolutionary self-organizing emergence of late medieval and
early modern fairs, and its robustness during the 17th and 18th century
Prospective acceptability of a multipurpose technology (MPT) implant in preclinical development to prevent HIV and unplanned pregnancy: Qualitative insights from women end users and health care providers in South Africa and Zimbabwe.
BackgroundGiven the high rates of both HIV and unintended pregnancies in sub-Saharan Africa, the SCHIELD program aims to develop a multipurpose technology implant for HIV and pregnancy prevention. An end-user evaluation was undertaken with young women and health care providers to assess preferences for modifiable implant attributes to improve future adoption and rollout.MethodsFocus group discussions were conducted with potential women end users, and health care providers experienced in implant insertion or removal participated in in-depth interviews. All participants were recruited from Harare, Zimbabwe, or Soshanguve, South Africa. The purposively stratified sampled women were either implant experienced or implant naĂŻve and were categorized into three groups: nulliparous, postpartum, or engaged in transactional sex. Topics covered included duration (six months to three years), biodegradability, removability, and independent rod retrievability (per indication). Data were analyzed using Dedoose software and summarized into emerging themes.ResultsParticipants identified three key areas that could facilitate rollout, uptake, and adherence of an implant for HIV and pregnancy prevention. First, discreetness was the most salient topic and was associated with implant characteristics such as anatomical location, flexibility, and biodegradability. Second, the ability to independently retrieve the HIV or pregnancy prevention component was preferred, as life circumstances may change and was favored by all participants, except for young women in Soshanguve. Third, there is a need for proper counseling, sensitization, provider training, and health campaigns to facilitate rollout of a 2-in-1 implant.ConclusionsA 2-in-1 implant was seen as highly desirable by most young women and health care providers. Participants discussed potential concerns and barriers to uptake of a biodegradable implant with dual HIV prevention and contraceptive properties, identifying key implant attributes that product developers can modify while still in preclinical stages
Demographic characteristics of all focus group discussion participants, by site and overall.
Demographic characteristics of all focus group discussion participants, by site and overall.</p