29 research outputs found

    The Impact of cold gas accretion above a mass floor on galaxy scaling relations

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    Using the cosmological baryonic accretion rate and normal star formation efficiencies, we present a very simple model for star-forming galaxies (SFGs) that accounts for the mass and redshift dependencies of the SFR-Mass and Tully-Fisher relations from z=2 to the present. The time evolution follows from the fact that each modelled galaxy approaches a steady state where the SFR follows the (net) cold gas accretion rate. The key feature of the model is a halo mass floor M_{min}~10^{11} below which accretion is quenched in order to simultaneously account for the observed slopes of the SFR-Mass and Tully-Fischer relations. The same successes cannot be achieved via a star-formation threshold (or delay) nor by varying the SF efficiency or the feedback efficiency. Combined with the mass ceiling for cold accretion due to virial shock heating, the mass floor M_{min} explains galaxy "downsizing", where more massive galaxies formed earlier and over a shorter period of time. It turns out that the model also accounts for the observed galactic baryon and gas fractions as a function of mass and time, and the cosmic SFR density from z~6 to z=0, which are all resulting from the mass floor M_{min}. The model helps to understand that it is the cosmological decline of accretion rate that drives the decrease of cosmic SFR density between z~2 and z=0 and the rise of the cosmic SFR density allows us to put a constraint on our main parameter M_{min}~10^{11} solar masses. Among the physical mechanisms that could be responsible for the mass floor, we view that photo-ionization feedback (from first in-situ hot stars) lowering the cooling efficiency is likely to play a large role.Comment: 19pages, 14 figures, accepted to ApJ, updated reference

    Incorporating end-users' voices into the development of an implant for HIV prevention : a discrete choice experiment in South Africa and Zimbabwe

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    AVAILABILITY OF DATA AND MATERIALS : The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.BACKGROUND : Input from end-users during preclinical phases can support market fit for new HIV prevention technologies. With several long-acting pre-exposure prophylaxis (PrEP) implants in development, we aimed to understand young women’s preferences for PrEP implants to inform optimal design. METHODS : We developed a discrete choice experiment and surveyed 800 young women in Harare, Zimbabwe and Tshwane, South Africa between September–November 2020. Women aged 18–30 years who were nulliparous, postpartum, or exchanged sex for money, goods or shelter in prior year were eligible; quotas were set for each subgroup. The DCE asked participants to choose between two hypothetical implants for HIV prevention in a series of nine questions. Implants were described by: size, number of rods and insertion sites, duration (6-months, 1-year, 2-years), flexibility, and biodegradability. Random-parameters logit models estimated preference weights. RESULTS : Median age was 24 years (interquartile range 21–27). By design, 36% had used contraceptive implants. Duration of protection was most important feature, with strong preference for a 2-year over 6-month implant. In Zimbabwe, the number of rods/insertion sites was second most important and half as important as duration. Nonetheless, to achieve an implant lasting 2-years, 74% were estimated to accept two rods, one in each arm. In South Africa, preference was for longer, flexible implants that required removal, although each of these attributes were one-third as important as duration. On average, biodegradability and size did not influence Zimbabwean women’s choices. Contraceptive implant experience and parity did not influence relative importance of attributes. CONCLUSIONS : While duration of protection was a prominent attribute shaping women’s choices for PrEP implants, other characteristics related to discreetness were relevant. Optimizing for longest dosing while also ensuring minimal detection of implant placement seemed most attractive to potential users.The American people through the United States Agency for International Development (USAID), U.S. President’s Emergency Plan for AIDS Relief as well as the support of the Bill & Melinda Gates Foundation.https://bmcwomenshealth.biomedcentral.comam2024Medical MicrobiologySDG-03:Good heatlh and well-bein

    Cuspy No More: How Outflows Affect the Central Dark Matter and Baryon Distribution in Lambda CDM Galaxies

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    We examine the evolution of the inner dark matter (DM) and baryonic density profile of a new sample of simulated field galaxies using fully cosmological, Lambda CDM, high resolution SPH + N-Body simulations. These simulations include explicit H2 and metal cooling, star formation (SF) and supernovae (SNe) driven gas outflows. Starting at high redshift, rapid, repeated gas outflows following bursty SF transfer energy to the DM component and significantly flatten the originally `cuspy' central DM mass profile of galaxies with present day stellar masses in the 10^4.5 -- 10^9.8 Msolar range. At z=0, the central slope of the DM density profile of our galaxies (measured between 0.3 and 0.7 kpc from their centre) is well fitted by rhoDM propto r^alpha with alpha \simeq -0.5 + 0.35 log_10(Mstar/10^8Msolar) where Mstar is the stellar mass of the galaxy and 4 < log_10 Mstar < 9.4. These values imply DM profiles flatter than those obtained in DM--only simulations and in close agreement with those inferred in galaxies from the THINGS and LITTLE THINGS survey. Only in very small halos, where by z=0 star formation has converted less than ~ 0.03% of the original baryon abundance into stars, outflows do not flatten the original cuspy DM profile out to radii resolved by our simulations. The mass (DM and baryonic) measured within the inner 500 pc of each simulated galaxy remains nearly constant over four orders of magnitudes in stellar mass for Mstar 10^9 Msolar. This finding is consistent with estimates for faint Local Group dwarfs and field galaxies. These results address one of the outstanding problems faced by the CDM model, namely the strong discrepancy between the original predictions of cuspy DM profiles and the shallower central DM distribution observed in galaxies.Comment: MNRAS in press. Accepted version, a few references added. 12 pages. Animation at http://youtu.be/FbcgEovabDI?hd=

    The Beginning and Evolution of the Universe

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    We review the current standard model for the evolution of the Universe from an early inflationary epoch to the complex hierarchy of structure seen today. We summarize and provide key references for the following topics: observations of the expanding Universe; the hot early Universe and nucleosynthesis; theory and observations of the cosmic microwave background; Big Bang cosmology; inflation; dark matter and dark energy; theory of structure formation; the cold dark matter model; galaxy formation; cosmological simulations; observations of galaxies, clusters, and quasars; statistical measures of large-scale structure; and measurement of cosmological parameters. We conclude with discussion of some open questions in cosmology. This review is designed to provide a graduate student or other new worker in the field an introduction to the cosmological literature.Comment: 69 pages. Invited review article for Publications of the Astronomical Society of the Pacific. Supplementary references, tables, and more concise PDF file at http://www.physics.drexel.edu/univers

    The stellar halo of the Galaxy

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    Stellar halos may hold some of the best preserved fossils of the formation history of galaxies. They are a natural product of the merging processes that probably take place during the assembly of a galaxy, and hence may well be the most ubiquitous component of galaxies, independently of their Hubble type. This review focuses on our current understanding of the spatial structure, the kinematics and chemistry of halo stars in the Milky Way. In recent years, we have experienced a change in paradigm thanks to the discovery of large amounts of substructure, especially in the outer halo. I discuss the implications of the currently available observational constraints and fold them into several possible formation scenarios. Unraveling the formation of the Galactic halo will be possible in the near future through a combination of large wide field photometric and spectroscopic surveys, and especially in the era of Gaia.Comment: 46 pages, 16 figures. References updated and some minor changes. Full-resolution version available at http://www.astro.rug.nl/~ahelmi/stellar-halo-review.pd

    Damped Lyman Alpha Systems in Galaxy Formation Simulations

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    We investigate the population of z=3 damped Lyman alpha absorbers (DLAs) in a recent series of high resolution galaxy formation simulations. The simulations are of interest because they form at z=0 some of the most realistic disk galaxies to date. No free parameters are available in our study: these have been fixed by physical and z=0 observational constraints, and thus our study provides a genuine consistency test. The precise role of DLAs in galaxy formation remains in debate, but they provide a number of strong constraints on the nature of our simulated bound systems at z=3 because of their coupled information on neutral H I densities, kinematics, metallicity and estimates of star formation activity. Our results, without any parameter-tuning, closely match the observed incidence rate and column density distributions of DLAs. Our simulations are the first to reproduce the distribution of metallicities (with a median of Z_{DLA} = Z_{solar}/20) without invoking observationally unsupported mechanisms such as dust biasing. This is especially encouraging given that these simulations have previously been shown to have a realistic 0<z<2 stellar mass-metallicity relation. Additionally, we see a strong positive correlation between sightline metallicity and low-ion velocity width, the normalization and slope of which comes close to matching recent observational results. However, we somewhat underestimate the number of observed high velocity width systems; the severity of this disagreement is comparable to other recent DLA focused studies. By z=0 the majority of the z=3 neutral gas forming the DLAs has been converted into stars, in agreement with rough physical expectations. [Abridged]Comment: 24 pages, 18 figures, MNRAS in press. Minor update with a few added details and typographical/grammatical fixes. Movie at http://www.ast.cam.ac.uk/~app26

    MAGICC haloes: confronting simulations with observations of the circumgalactic medium at z=0

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    We explore the circumgalactic medium (CGM) of two simulated star-forming galaxies with luminosities L ~ 0.1 and 1 L* generated using the smooth particle hydrodynamic code GASOLINE. These simulations are part of the Making Galaxies In a Cosmological Context (MAGICC) program in which the stellar feedback is tuned to match the stellar mass-halo mass relationship. For comparison, each galaxy was also simulated using a 'lower feedback' (LF) model which has strength comparable to other implementations in the literature. The 'MAGICC feedback' (MF) model has a higher incidence of massive stars and an approximately two times higher energy input per supernova. Apart from the low-mass halo using LF, each galaxy exhibits a metal-enriched CGM that extends to approximately the virial radius. A significant fraction of this gas has been heated in supernova explosions in the disc and subsequently ejected into the CGM where it is predicted to give rise to substantial O VI absorption. The simulations do not yet address the question of what happens to the O VI when the galaxies stop forming stars. Our models also predict a reservoir of cool H I clouds that show strong Ly\alpha absorption to several hundred kpc. Comparing these models to recent surveys with the Hubble Space Telescope, we find that only the MF models have sufficient O VI and H I gas in the CGM to reproduce the observed distributions. In separate analyses, these same MF models also show better agreement with other galaxy observables (e.g. rotation curves, surface brightness profiles and H I gas distribution). We infer that the CGM is the dominant reservoir of baryons for galaxy haloes.Comment: 9 pages, 7 figures, submitted MNRAS, comments welcom

    The economics of debt clearing mechanisms

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    We examine the evolution of decentralized clearinghouse mechanisms from the 13th to the 18th century; in particular, we explore the clearing of non- or limitedtradable debts like bills of exchange. We construct a theoretical model of these clearinghouse mechanisms, similar to the models in the theoretical matching literature, and show that specific decentralized multilateral clearing algorithms known as rescontre, skontrieren or virement des parties used by merchants were efficient in specific historical contexts. We can explain both the evolutionary self-organizing emergence of late medieval and early modern fairs, and its robustness during the 17th and 18th century

    Prospective acceptability of a multipurpose technology (MPT) implant in preclinical development to prevent HIV and unplanned pregnancy: Qualitative insights from women end users and health care providers in South Africa and Zimbabwe.

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    BackgroundGiven the high rates of both HIV and unintended pregnancies in sub-Saharan Africa, the SCHIELD program aims to develop a multipurpose technology implant for HIV and pregnancy prevention. An end-user evaluation was undertaken with young women and health care providers to assess preferences for modifiable implant attributes to improve future adoption and rollout.MethodsFocus group discussions were conducted with potential women end users, and health care providers experienced in implant insertion or removal participated in in-depth interviews. All participants were recruited from Harare, Zimbabwe, or Soshanguve, South Africa. The purposively stratified sampled women were either implant experienced or implant naĂŻve and were categorized into three groups: nulliparous, postpartum, or engaged in transactional sex. Topics covered included duration (six months to three years), biodegradability, removability, and independent rod retrievability (per indication). Data were analyzed using Dedoose software and summarized into emerging themes.ResultsParticipants identified three key areas that could facilitate rollout, uptake, and adherence of an implant for HIV and pregnancy prevention. First, discreetness was the most salient topic and was associated with implant characteristics such as anatomical location, flexibility, and biodegradability. Second, the ability to independently retrieve the HIV or pregnancy prevention component was preferred, as life circumstances may change and was favored by all participants, except for young women in Soshanguve. Third, there is a need for proper counseling, sensitization, provider training, and health campaigns to facilitate rollout of a 2-in-1 implant.ConclusionsA 2-in-1 implant was seen as highly desirable by most young women and health care providers. Participants discussed potential concerns and barriers to uptake of a biodegradable implant with dual HIV prevention and contraceptive properties, identifying key implant attributes that product developers can modify while still in preclinical stages
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