COLLECTIVE AUTONOMY RESTRICTION: A THEORETICAL MODEL AND EMPIRICAL INVESTIGATIONS

Collective autonomy refers to a group’s freedom to define and practice their own cultural and social identity without interference from other groups. According to the “threat and defense” hypothesis of collective autonomy restriction, group members are motivated to defend their collective autonomy from outside restriction. However, the psychological processes that influence advantaged vs. disadvantaged group members perceptions of collective autonomy, as well as the specific strategies they use to protect collective autonomy, have yet to be articulated. This dissertation presents three manuscripts that examine the social conditions and psychological processes that shape advantaged and disadvantaged group members’ perceptions of collective autonomy. The first manuscript (Chapter 2) is a theoretical review that articulates hypotheses about the social conditions (i.e., stability vs. instability of a social hierarchy and its perceived legitimacy) and psychological process (i.e., social identity strength, system beliefs, social comparisons, and intergroup threat) that shape advantaged and disadvantaged group members’ perceptions of collective autonomy restriction and drive collective action. The second manuscript (Chapter 3) empirically tests whether social instability and hierarchy threat increases feelings of collective autonomy restriction among politically advantaged group members. Finally, the third manuscript (Chapter 4), empirically tests the external validity of the collective autonomy restriction literature by testing whether experiencing racial/ethnic collective autonomy shapes adolescents’ perceptions of their teachers as supportive of their intrinsic motivational needs within the classroom context. A summary of each manuscript, as well as their theoretical and practical implications for future research are discussed (Chapter 5)

Teacher\u27s Discipline Practices and Race: The Effect of Fair and Unfair Discipline on Black and White Student\u27s Perceptions and Behaviors

Negative stereotypes characterizing Black males as prone to causing trouble can lead teachers to punish misbehaving Black boys more harshly than their White peers. Awareness of unfair discipline practices has been linked to future disciplinary infractions among Black males, hinting that some Black males may engage in defiant behavior in response to unfair discipline. Despite the documented links between awareness of unfair discipline and future disciplinary infractions among Black males, questions remain as to (1) the types of disciplinary practices from teachers that students perceive as fair and unfair; (2) the psychological processes that motivate Black male behavior after experiencing unfair discipline; and (3) whether these psychological processes differ from those that motivate White male behavior. Across three studies, the present research explores these questions by asking Black and White men to recall the type of treatment from teachers that they perceived as fair and unfair (Study 2), as well as how they would have perceived and responded to different scenarios describing instances of either fair and unfair discipline from teachers in middle and high school (Studies 1 and 3). Qualitative results from Study 2 highlights negotiable (i.e., a collaborative effort between a teacher and their pupil to discuss and analyze how and why a particular situation arose from all perspectives) and non-negotiable (i.e., teacher ignores the pupil’s explanation for the infraction) discipline as two contrasting practices that men viewed as fair and unfair, respectively. Quantitative results from Study 3 indicated that unfair (non-negotiable), compared to fair (negotiable) discipline from teachers triggered negative emotions associated with reputation threat (i.e., embarrassment, shame, anger, and sadness), which in turn predicted future defiant behavior among both Black and White men. Furthermore, the extent to which unfair discipline from teachers was attributed to racial bias also predicted greater negative emotions and defiant behavior for Black, but not White, men. Together, these findings shed light on a process through which unfair disciplinary practices may motivate defiance from students via negative emotions among both Black and White students; as well as the unique role that race bias attributions have on Black students’ perceptions of unfair discipline

Racial/ethnic collective autonomy restriction and teacher fairness: predictors and moderators of student's perceptions of teacher support

The link between intrinsic motivation support from teachers (i.e., teacher support), academic motivation, and academic performance is well documented. However, evidence suggests that racial/ethnic minority students are less likely to perceive support from adults at school, compared to White students. The majority of existing research has emphasized the impact that school-level factors have on racial/ethnic minority students' perceptions of teacher support. However, less research has examined whether students' awareness of racial/ethnic inequality at the socio-structural level may also influence perceptions of teacher support. The present study explores this question and examines whether students' perceptions of race/ethnic based collective autonomy restriction (i.e., the extent to which an individual feels that other groups try and restrict their racial/ethnic groups' freedom to define and express their own social identity) and fair treatment from teachers influence these outcomes. Drawing on cross-sectional survey data from middle and high school students (N = 110), the present study found that racial/ethnic minority students reported greater perceptions of collective autonomy restriction, compared to White students, which mediated the link between students' racial/ethnic identity and perceived teacher support. Furthermore, past experiences with fair treatment from teachers were found to buffer the link between collective autonomy restriction and perceptions of teacher support. The practical implications of these findings for educators to better support students from underrepresented racial/ethnic backgrounds are discussed

Anger, race, and the neurocognition of threat: attention, inhibition, and error processing during a weapon identification task

This study measured event-related brain potentials (ERPs) to test competing hypotheses regarding the effects of anger and race on early visual processing (N1, P2, and N2) and error recognition (ERN and Pe) during a sequentially primed weapon identification task. The first hypothesis was that anger would impair weapon identification in a biased manner by increasing attention and vigilance to, and decreasing recognition and inhibition of weapon identification errors following, task-irrelevant Black (compared to White) faces. Our competing hypothesis was that anger would facilitate weapon identification by directing attention toward task-relevant stimuli (i.e., objects) and away from task-irrelevant stimuli (i.e., race), and increasing recognition and inhibition of biased errors. Results partially supported the second hypothesis, in that anger increased early attention to faces but minimized attentional processing of race, and did not affect error recognition. Specifically, angry (vs. neutral) participants showed increased N1 to both Black and White faces, ablated P2 race effects, and topographically restricted N2 race effects. Additionally, ERN amplitude was unaffected by emotion, race, or object type. However, Pe amplitude was affected by object type (but not emotion or race), such that Pe amplitude was larger after the misidentification of harmless objects as weapons. Finally, anger slowed overall task performance, especially the correct identification of harmless objects, but did not impact task accuracy. Task performance speed and accuracy were unaffected by the race of the face prime. Implications are discussed

High-Dose vs. Low-Dose Dexamethasone in Patients With COVID-19: A Cohort Study in Rural Central America

To compare the clinical outcomes of a low dose dexamethasone strategy vs. a high-dose dexamethasone strategy in hypoxemic COVID-19 patients. A retrospective observational study comparing low-dose (8 mg) and high-dose dexamethasone (24 mg) of COVID-19 patients admitted from September 1, 2020 to October 31, 2020 in a hospital in Honduras. We included 81 patients with confirmed COVID-19 who required oxygen therapy. The mean age was similar between groups (57.49 vs. 56.95 years). There were more male patients in the group of 24 mg (p = 0.01). Besides, patients on the 24 mg dose had more prevalence of hypertension (p = 0.052). More patients in the 24 mg group had a higher rate of invasive mechanical ventilation (15.00% vs. 2.56%, p = 0.058). When evaluating the association between the high dose group and outcomes, we find no significant association with mortality, nosocomial infections, high flow mask, invasive mechanical ventilation, or the need for vasopressors. We find no significant differences in the Kaplan–Meier analysis regarding the survival (log-rank p-value = 0.315). We did not find significant differences between the use of 24 mg and 8 mg of dexamethasone in hypoxemic COVID-19 patients.Revisión por pare

Binational reflections on pathways to groundwater security in the Mexico-United States borderlands

Shared groundwater resources between Mexico and the United States are facing unprecedented stressors. We reflect on how to improve water security for groundwater systems in the border region. Our reflection begins with the state of groundwater knowledge, and the challenges groundwater resources face from a physical, societal and institutional perspective. We conclude that the extent of ongoing cooperation frameworks, joint and remaining research efforts, from which alternative strategies can emerge, still need to be developed. The way forward offers a variety of cooperation models as the future offers rather complex, shared and multidisciplinary water challenges to the Mexico–US borderlands

Binational reflections on pathways to groundwater security in the Mexico–United States borderlands

Shared groundwater resources between Mexico and the United States are facing unprecedented stressors. We reflect on how to improve water security for groundwater systems in the border region. Our reflection begins with the state of groundwater knowledge, and the challenges groundwater resources face from a physical, societal and institutional perspective. We conclude that the extent of ongoing cooperation frameworks, joint and remaining research efforts, from which alternative strategies can emerge, still need to be developed. The way forward offers a variety of cooperation models as the future offers rather complex, shared and multidisciplinary water challenges to the Mexico–US borderlands

B-Chronic Lymphocytic Leukemia Autophagyc Cell Death by the Use of Manganese Doped Zinc Oxide Nanoparticles and Photo-Dynamic Therapy

B-Chronic Lymphocytic Leukemia (B-CLL) usually follows an adverse, relentless clinical course by slowly developing drug resistance to fludarabine and other chemotherapeutic agents, as well as by acquiring new different genetic abnormalities. As B-CLL cells spontaneously produce high amounts of Reactive Oxygen Species (ROS) having an altered redox state in relation to that of normal B lymphocytes, we decided to probe different metal Zinc nanoparticles (ZnNPs) and quantify the levels of Singlet Oxigen (SO) to see if variations of its intracellular concentrations could execute and accelerate deadly programs in leukemic cells rather than in normal B lymphocytes, when applied with Photodynamic Therapy (PDT). In this way, we developed and tested a variety of metal ZnNPs of which one made of 0.5% Manganese Doped Zinc Oxide (ZnO:Mn) was finally selected for further testing as it had the best fludarabine resistant B-CLL cells in vitro killing activity, specially when combined with PDT. An interesting and rapidly dying process of B-CLL cells, known as autophagy, was always seen under Transmission Electronic Microscopy (TEM) when incubated with these 0.5% Mn doped ZnO NPs. This phenomenon correlated well with those intracellular increases of SO when PDT was administered, and measured by a novel method first described by us. As this therapy seems to be very specific to fludarabine resistant B-CLL cells, producing almost no damage to normal lymphocytes, it could surely contribute in the near future as a new innovative targeted strategy to be delivered in the clinical setting for the definitive benefit of these bad prognostic patients.Facultad de Ciencias MédicasInstituto de Investigaciones Bioquímicas de La PlataFacultad de Ciencias Exacta

Arecibon planetaarisen tutkan Maan lähiasteroidihavainnot: 2017 joulukuu - 2019 joulukuu

We successfully observed 191 near-Earth asteroids using the Arecibo Observatory's S-band planetary radar system from 2017 December through 2019 December. We present radar cross sections for 167 asteroids; circular-polarization ratios for 112 asteroids based on Doppler-echo-power spectra measurements; and radar albedos, constraints on size and spin periods, and surface-feature and shape evaluation for 37 selected asteroids using delay-Doppler radar images with a range resolution of 75 m or finer. Out of 33 asteroids with an estimated effective diameter of at least 200 m and sufficient image quality to give clues of the shape, at least 4 (∼12%) are binary asteroids, including 1 equal-mass binary asteroid, 2017 YE5, and at least 10 (∼30%) are contact-binary asteroids. For 5 out of 112 asteroids with reliable measurements in both circular polarizations, we measured circular-polarization ratios greater than 1.0, which could indicate that they are E-type asteroids, while the mean and the 1σ standard deviation were 0.37 ± 0.23. Further, we find a mean opposite-sense circular-polarization radar albedo of 0.21 ± 0.11 for 41 asteroids (0.19 ± 0.06 for 11 S-complex asteroids). We identified two asteroids, 2011 WN15 and (505657) 2014 SR339, as possible metal-rich objects based on their unusually high radar albedos, and discuss possible evidence of water ice in 2017 YE5.Peer reviewe

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London