118 research outputs found

    Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

    Get PDF
    Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field

    Enzyme production from food wastes using a biorefinery concept

    Get PDF
    According to Food and Agricultural Organization (FAO), one-third of food produced globally for human consumption (nearly 1.3 billion tonnes) is lost along the food supply chain. In many countries food waste is currently landfilled or incinerated together with other combustible municipal wastes for possible recovery of energy. However, these two options are facing more and more economic and environmental stresses. Due to its organic- and nutrient-rich nature, theoretically food waste can be converted to valuable products (e.g. bio-products such as methane, hydrogen, ethanol, enzymes, organic acids, chemicals and fuels) through various fermentation processes. Such conversion of food waste is potentially more profitable than its conversion to animal feed or transportation fuel. Food waste valorisation has therefore gained interest, with value added bio-products such as methane, hydrogen, ethanol, enzymes, organic acids, chemicals, and fuels. Therefore, the aim of this review is to provide information on the food waste situation with emphasis on Asia–Pacific countries and the state of the art food waste processing technologies to produce enzymes

    Efficacy of Major Plant Extracts/Molecules on Field Insect Pests

    Get PDF
    Insect pests are considered the major hurdle in enhancing the production and productivity of any farming system. The use of conventional synthetic pesticides has led to the emergence of pesticide-resistant insects, environmental pollution, and negative effects on natural enemies, which have caused an ecological imbalance of the predator-prey ratio and human health hazards; therefore, eco-friendly alternative strategies are required. The plant kingdom, a rich repertoire of secondary metabolites, can be tapped as an alternative for insect pest management strategies. A number of plants have been documented to have insecticidal properties against various orders of insects in vitro by acting as antifeedants, repellents, sterilant and oviposition deterrents, etc. However, only a few plant compounds are applicable at the field level or presently commercialised. Here, we have provided an overview of the broad-spectrum insecticidal activity of plant compounds from neem, Annona, Pongamia, and Jatropha. Additionally, the impact of medicinal plants, herbs, spices, and essential oils has been reviewed briefl

    The twisted survivin connection to angiogenesis

    Get PDF

    Agrotis EPN Data

    No full text
    <p>The present study was, undertaken with the objective to assess the virulence of local isolates of EPNs of Himachal Pradesh, <i>Heterorhabditis</i> sp. against black cut worm, <i>Agrotis segetum</i> in order to minimize the use of insecticides during crop protection. Against L3-5 of <i>A. segetum, H. indica </i>was found highly effective, resulting into 33.33-93.33 per cent mortality at 40 IJs/larva after 96 hours of treatment. Among local isolates, <i>Heterorhabditis </i>sp.<i> </i>(HSG) influenced maximum mortality of L3 and L4, whereas in L5, <i>H. bacteriophora </i>(HRJ)<i> </i>influenced maximum mortality. The sensitivity of L3 to different entomopathogenic nematodes was 7.0-16.6 % higher as compared to L4. In soil bioassay carried out against L4 of <i>A. segetum</i>, <i>H. bacteriophora </i>(HRJ) was found highly effective followed by <i>Heterorhabditis </i>sp.<i> </i>(HKM) and <i>Heterorhabditis </i>sp.<i> </i>(HSG) at 10000 IJs/kg of soil. The mortality varied from 78.33-81.67 % after 7 days of treatment with local isolates. </p

    Diversity and population dynamics of phytophagous scarabaeid beetles (Coleoptera: Scarabaeidae) in different landscapes of Himachal Pradesh, India

    No full text
    Scarabaeid beetles constitute a major group of defoliators of cultivated and wild plants. Therefore, it is important to understand their diversity, abundance and distribution for planning effective pest management programmes. We surveyed scarabaeid beetles from 8 landscapes from different zones in Himachal Pradesh (N 32o 29' and E 75o 10'), India. In 2011 and 2012, surveys were conducted during 4 months period (May-August) by using UV light traps. A total of 13,569 scarabaeid adults of 20 genera and 56 species belonging to subfamilies Melolonthinae, Rutelinae, Cetoniinae and Dynastinae were recorded. The five most common species were Brahmina coriacea, Adoretus lasiopygus, Anomala lineatopennis, Maladera insanabilis and Holotrichia longipennis. They comprised 9.88-10.05, 7.18-7.76, 7.13-7.27, 6.80-7.62 and 5.22-5.30 % during 2011-12, respectively. Anomala (10 species) was the most dominant genus in the present study, whereas Melolonthinae was the most dominant subfamily accounting 53.23 percent of total scarabs collected from the study sites. Among different landscapes, Palampur had maximum diversity and abundance, while Shillaroo had least diversity but more abundance of single species B. coriacea. The value of alpha diversity indices viz. Shannon index was maximum (H'=3.01-3.03) at Palampur. This indicates maximum evenness and abundance of species at Palampur. Shillaroo had lowest Shannon index (H'=1.12-1.17) and Pielou's evenness index (J'=0.46-0.49). This showed least species diversity and higher unevenness of scarabaeid beetles at Shillaroo. The results of beta diversity analysis revealed poor similarity of scarabaeid species between different sites confirming that the scarabaeid community in the north western Himalayan regions is much diverse

    Not Available

    No full text
    Not AvailableNot AvailableNot Availabl

    Insect pests of potato-I: Root and tuber eating pests

    No full text
    Not AvailableNot AvailableNot Availabl
    corecore