Search for cold gas in strong MgII absorbers at 0.5<z<1.5: nature and evolution of 21-cm absorbers

We report 4 new detections of 21-cm absorption from a systematic search of 21-cm absorption in a sample of 17 strong (Wr(MgII 2796)>1A) intervening MgII absorbers at 0.5<z<1.5. We also present 20-cm milliarcsecond scale maps of 40 quasars having 42 intervening strong MgII absorbers for which we have searched for 21-cm absorption. Combining 21-cm absorption measurements for 50 strong MgII systems from our surveys with the measurements from literature, we obtain a sample of 85 strong MgII absorbers at 0.5<z<1 and 1.1<z<1.5. We present detailed analysis of this sample, taking into account the effect of the varying 21-cm optical depth sensitivity and covering factor associated with the different quasar sight lines. We find that the 21-cm detection rate is higher towards the quasars with flat or inverted spectral index at cm wavelengths. About 70% of 21-cm detections are towards the quasars with linear size, LS<100 pc. The 21-cm absorption lines having velocity widths, DeltaV>100 km/s are mainly seen towards the quasars with extended radio morphology at arcsecond scales. However, we do not find any correlation between the integrated 21-cm optical depth or DeltaV with the LS measured from the milliarcsecond scale images. All this can be understood if the absorbing gas is patchy with a typical correlation length of ~30-100 pc. We show that within the measurement uncertainty, the 21-cm detection rate in strong MgII systems is constant over 0.5<z<1.5, i.e., over ~30% of the total age of universe. We show that the detection rate can be underestimated by up to a factor 2 if 21-cm optical depths are not corrected for the partial coverage estimated using milliarcsecond scale maps. Since stellar feedback processes are expected to diminish the filling factor of cold neutral medium over 0.5<z<1, this lack of evolution in the 21-cm detection rate in strong MgII absorbers is intriguing. [abridged]Comment: 28 pages, 14 figures, 9 tables, accepted for publication in Astronomy and Astrophysic

The X-ray absorbing column density of a complete sample of bright Swift Gamma-Ray Bursts

A complete sample of bright Swift Gamma-ray Bursts (GRBs) has been recently selected by Salvaterra et al. (2011). The sample has a high level of completeness in redshift (91%). We derive here the intrinsic absorbing X-ray column densities of these GRBs making use of the Swift X-ray Telescope data. This distribution has a mean value of log(NH/cm-2)=21.7+-0.5. This value is consistent with the distribution of the column densities derived from the total sample of GRBs with redshift. We find a mild increase of the intrinsic column density with redshift. This can be interpreted as due to the contribution of intervening systems along the line of sight. Making use of the spectral index connecting optical and X-ray fluxes at 11 hr (beta_OX), we investigate the relation of the intrinsic column density and the GRB `darkness'. We find that there is a very tight correlation between dark GRBs and high X-ray column densities. This clearly indicates that the dark GRBs are formed in a metal-rich environment where dust must be present.Comment: MNRAS, 6 pages, 3 figures, 1 tabl

Calibration and sensitivity of the Virgo detector during its second science run

The Virgo detector is a kilometer-length interferometer for gravitational wave detection located near Pisa (Italy). During its second science run (VSR2) in 2009, six months of data were accumulated with a sensitivity close to its design. In this paper, the methods used to determine the parameters for sensitivity estimation and gravitational wave reconstruction are described. The main quantities to be calibrated are the frequency response of the mirror actuation and the sensing of the output power. Focus is also put on their absolute timing. The monitoring of the calibration data as well as the parameter estimation with independent techniques are discussed to provide an estimation of the calibration uncertainties. Finally, the estimation of the Virgo sensitivity in the frequency-domain is described and typical sensitivities measured during VSR2 are shown.Comment: 30 pages, 23 figures, 1 table. Published in Classical and Quantum Gravity (CQG), Corrigendum include

Directional limits on persistent gravitational waves using LIGO S5 science data

The gravitational-wave (GW) sky may include nearby pointlike sources as well as astrophysical and cosmological stochastic backgrounds. Since the relative strength and angular distribution of the many possible sources of GWs are not well constrained, searches for GW signals must be performed in a model-independent way. To that end we perform two directional searches for persistent GWs using data from the LIGO S5 science run: one optimized for pointlike sources and one for arbitrary extended sources. The latter result is the first of its kind. Finding no evidence to support the detection of GWs, we present 90% confidence level (CL) upper-limit maps of GW strain power with typical values between 2-20x10^-50 strain^2 Hz^-1 and 5-35x10^-49 strain^2 Hz^-1 sr^-1 for pointlike and extended sources respectively. The limits on pointlike sources constitute a factor of 30 improvement over the previous best limits. We also set 90% CL limits on the narrow-band root-mean-square GW strain from interesting targets including Sco X-1, SN1987A and the Galactic Center as low as ~7x10^-25 in the most sensitive frequency range near 160 Hz. These limits are the most constraining to date and constitute a factor of 5 improvement over the previous best limits.Comment: 10 pages, 4 figure

Seasonal pattern of peptic ulcer hospitalizations: analysis of the hospital discharge data of the Emilia-Romagna region of Italy

BACKGROUND: Previous studies have reported seasonal variation in peptic ulcer disease (PUD), but few large-scale, population-based studies have been conducted. METHODS: To verify whether a seasonal variation in cases of PUD (either complicated or not complicated) requiring acute hospitalization exists, we assessed the database of hospital admissions of the region Emilia Romagna (RER), Italy, obtained from the Center for Health Statistics, between January 1998 and December 2005. Admissions were categorized by sex, age ( or = 75 yrs), site of PUD lesion (stomach or duodenum), main complication (hemorrhage or perforation), and final outcome (intended as fatal outcome: in-hospital death; nonfatal outcome: patient discharged alive). Temporal patterns in PUD admissions were assessed in two ways, considering a) total counts per single month and season, and b) prevalence proportion, such as the monthly prevalence of PUD admissions divided by the monthly prevalence of total hospital admissions, to assess if the temporal patterns in the raw data might be the consequence of seasonal and annual variations in hospital admissions per se in the region. For statistical analysis, the chi2 test for goodness of fit and inferential chronobiologic method (Cosinor and partial Fourier series) were used. RESULTS: Of the total sample of PUD patients (26,848 [16,795 males, age 65 +/- 16 yrs; 10,053 females, age 72 +/- 15 yrs, p or = 75 yrs of age. There were more cases of duodenal (DU). (89.8%) than gastric ulcer (GU) (3.6%), and there were 1,290 (4.8%) fatal events. Data by season showed a statistically difference with the lowest proportion of PUD hospital admissions in summer (23.3%) (p < 0.001), for total cases and rather all subgroups. Chronobiological analysis identified three major peaks of PUD hospitalizations (September-October, January-February, and April-May) for the whole sample (p = 0.035), and several subgroups, with nadir in July. Finally, analysis of the monthly prevalence proportions yielded a significant (p = 0.025) biphasic pattern with a main peak in August-September-October, and a secondary one in January-February. CONCLUSIONS: A seasonal variation in PUD hospitalization, characterized by three peaks of higher incidence (Autumn, Winter, and Spring) is observed. When data corrected by monthly admission proportions are analyzed, late summer-autumn and winter are confirmed as higher risk periods. The underlying pathophysiologic mechanisms are unknown, and need further studies. In subjects at higher risk, certain periods of the year could deserve an appropriate pharmacological protection to reduce the risk of PUD hospitalization

Macrophages promote angiogenesis in human breast tumour spheroids in vivo

An in vivo model has been established to study the role of macrophages in the initiation of angiogenesis by human breast tumour spheroids in vivo. The extent of the angiogenic response induced by T47D spheroids implanted into the dorsal skinfold chamber in nude mice was measured in vivo and compared to that induced by spheroids infiltrated with human macrophages prior to implantation. Our results indicate that the presence of macrophages in spheroids resulted in at least a three-fold upregulation in the release of vascular endothelial growth factor (VEGF) in vitro when compared with spheroids composed only of tumour cells. The angiogenic response measured around the spheroids, 3 days after in vivo implantation, was significantly greater in the spheroids infiltrated with macrophages. The number of vessels increased (macrophages vs no macrophages 34±1.9 vs 26±2.5, P<0.01), were shorter in length (macrophages vs no macrophages 116±4.92 vs 136±6.52, P<0.008) with an increased number of junctions (macrophages vs no macrophages 14±0.93 vs 11±1.25, P<0.025) all parameters indicative of new vessel formation. This is the first study to demonstrate a role for macrophages in the initiation of tumour angiogenesis in vivo

Properties of galaxies reproduced by a hydrodynamic simulation.

Previous simulations of the growth of cosmic structures have broadly reproduced the 'cosmic web' of galaxies that we see in the Universe, but failed to create a mixed population of elliptical and spiral galaxies, because of numerical inaccuracies and incomplete physical models. Moreover, they were unable to track the small-scale evolution of gas and stars to the present epoch within a representative portion of the Universe. Here we report a simulation that starts 12 million years after the Big Bang, and traces 13 billion years of cosmic evolution with 12 billion resolution elements in a cube of 106.5 megaparsecs a side. It yields a reasonable population of ellipticals and spirals, reproduces the observed distribution of galaxies in clusters and characteristics of hydrogen on large scales, and at the same time matches the 'metal' and hydrogen content of galaxies on small scales