Control of Noise in Chemical and Biochemical Information Processing

We review models and approaches for error-control in order to prevent the buildup of noise when gates for digital chemical and biomolecular computing based on (bio)chemical reaction processes are utilized to realize stable, scalable networks for information processing. Solvable rate-equation models illustrate several recently developed methodologies for gate-function optimization. We also survey future challenges and possible new research avenues.Comment: 39 pages, 8 figures, PD

Stereoselective synthesis of novel conformationally restricted β- and γ-amino acids

Novel conformationally restricted β- and γ-amino acids containing a cyclopropane ring could be stereoselectively synthesized from readily available 5-methoxyindole and pyridine by copper(I)-catalyzed cyclopropanation with methyl diazoacetate followed by subsequent oxidative cleavage of the resulting adducts

Stereoselective synthesis of novel conformationally restricted β- and γ-amino acids

Novel conformationally restricted β- and γ-amino acids containing a cyclopropane ring could be stereoselectively synthesized from readily available 5-methoxyindole and pyridine by copper(I)-catalyzed cyclopropanation with methyl diazoacetate followed by subsequent oxidative cleavage of the resulting adducts

Functionalised 2,2 `-bipyridine ligands for the preparation of metallostars; X-ray structures of free ligands and preparation of copper(I) and silver(I) complexes

2,2-Bipyridine ligands bearing functionalised aryl substituents have been prepared with the aim of subsequent functionalisation and the preparation of multinuclear metallostars. The key intermediates are compounds containing 4-methoxyphenyl substituents which may be converted to 4-hydroxyphenyl substituted ligands. Copper(I) and silver(I) complexes of 4,4`-di(methoxyphenyl)-6,6`-dimethyl-2,2`-bipyridine have been prepared and structurally characterised as have the ligands 4,4`-di(methoxypheny1)-6,6`-dimethyl-2,2`-bipyridine and 4,4`-di(methoxyphenyl)-2,2`-bipyridine

Tris-chelate complexes with chiral ligands : in search of diastereoisomeric selectivity with remote stereogenic centres

The chiral ligands, 4,4`-bis(1S,2R,4S)-(-)-bornyloxy)-2,2`-bipyridine, (1S,2R,4S)-1, and 4,4`-bis(1R,2S,4R)-(+)-bornyloxy)-2,2`-bipyridine, (1R,2S,4R)-1, have been prepared and characterized by spectroscopic techniques and, for (1S,2R,4S)-1, by single crystal X-ray diffraction. Despite the use of enantiomerically pure ligands, the formation of the complexes [Fe((1S,2R,4S)-1)(3)](2+), [Ru((1S,2R,4S)-1)(3)](2+), [Ru((1S,2R,4S)-1)(bpy)(2)](2+) and [Ru((1R,2S,4R)-1)(bpy)(2)](2+) proceeds without preference for either the Delta or Lambda-diastereoisomers

A Ruthenium(II)-Complexed Rotaxane Whose Ring Incorporates a 6,6′-Diphenyl-2,2′-bipyridine: Synthesis and Light-Driven Motions

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