Improving Instructional Efficiency Through The Implementation Of Computerized Management And Prescriptive Analysis

The author implemented a computerized management system to improve instructional efficiency within the classroom. A variety of computer application software were used for grading and prescriptive analysis in the fifth grade classroom. The teacher developed a data base of student information, and parental contact was conducted via grade sheet reports and word processed form letters. Keyboard skills were taught to the students during their Computer Science and Language arts lab periods so that word processing skills could be introduced. No textbook was used for language arts instruction. The teacher modeled the writing process on the word processors and the students used this medium to produce written assignments. Reading groups, objective mastery, review instruction, test analysis, and objective tracking were all conducted via computer software reports. This program took place during one school year. Favorable evaluations were made from the recorded data on the Iowa Test of Basic Skills in the areas of Math, Reading, and Language Arts. Student demonstration of computer application skills was demonstrated throughout the year. The program was recommended to be adapted by other teachers in the author’s school. Appendices include surveys, changing test scores, model data bases, grade reports, and reading progress reports

Impact of vacuum-induced surface freezing on inter- and intra-vial heterogeneity

This paper aims to study the impact of freezing on both within-batch (inter-vial) and within- product (intra-vial) heterogeneity. This analysis has been carried out using two freezing protocols, the conventional shelf-ramped method and the Vacuum Induced Surface Freezing, and placebo formulations containing both crystallizing (mannitol) and amorphous (lactose and sucrose) excipients. The freezing conditions (i.e., the temperature of freezing, the temperature and time of the equilibration phase, and the filling volume) were found to have a dramatic impact on both the within-batch and the within-product homogeneity. Overall, we observed that the control of freezing can effectively minimize the variability in product characteristics, and moisture content, within the same batch. In addition to more uniform production, the control of freezing was found to be fundamental to achieve a more uniform product than that produced by the shelf-ramped freezing method. The influence of the freezing protocol on the crystallization process of mannitol was also investigated, showing that the temperature of freezing plays a key role in the formation of the mannitol polymorphs

Three Generations in Minimally Extended Standard Models

We present a class of minimally extended standard models with the gauge group $SU(3)_C \times SU(N)_L \times U(1)_X$ where for all $N \geq 3$, anomaly cancelation requires three generations. At low energy, we recover the Standard Model (SM), while at higher energies, there must exist quarks, leptons and gauge bosons with electric charges shifted from their SM values by integer multiples of the electron charge up to $\pm [N/2] e$. Since the value N=5 is the highest $N$ consistent with QCD asymptotic freedom, we elaborate on the 3-5-1 model.Comment: 9 pages, v3: version to appear in PL

HI in NGC 5433 and its Environment: High-Latitude Emission in a Small Galaxy Group

We present HI synthesis maps of the edge-on starburst NGC 5433 and its environment, obtained with the VLA in its C and D configurations. The observations and spectral model residuals of the main disc emission in NGC 5433 reveal 3 extraplanar features. We associate 2 of these features with coherent extraplanar extensions across multiple spectral channels in our data, including a complete loop in position-velocity space. Interpreting the latter as an expanding shell we derive a corresponding input energy of 2 x 10^54 ergs, comparable to that for the largest supershells found in the Galaxy and those in other edge-on systems. NGC 5433 is in a richer environment than previously thought. We confirm that KUG 1359+326 is a physical companion to NGC 5433 and find two new faint companions, both with Minnesota Automated Plate Scanner identifications, that we label SIS-1 and SIS-2. Including the more distant IC 4357, NGC 5433 is the dominant member of a group of at least 5 galaxies, spanning over 750 kpc in a filamentary structure. A variety of evidence suggests that interactions are occurring in this group. While a number of underlying mechanisms are consistent with the morphology of the high-latitude features in NGC 5433, we argue that environmental effects may play a role in their generation.Comment: 18 pages including 10 figures. Accepted for publication in MNRAS. For higher resolution Fig. 1, see http://www.astro.cornell.edu/~spekkens/papers/ v2: Proof-corrected cop

Five Geneseo Monuments: Exhibition Catalog

SUNY Geneseo Museum Studies Class Exhibition, Fall 2019. Bridge Gallery, December 4, 2019. The Big Tree The Bear Fountain Monument: A Symbol of Community James Samuel Wadsworth Statue Progression Toward Modernity: Geneseo’s Suffragists, The Shaw Sisters The Geneseo Fire Department Memorialhttps://knightscholar.geneseo.edu/geneseo-authors/1009/thumbnail.jp

Nestemäisten jätteiden vastaanotto ja käsittely Tarastenjärven jätekeskuksessa : Selvitys vaihtoehtoisista menetelmistä

Nestemäiset jätteet ovat erilaisia loka-autoilla kuljetettavia jätteitä, jotka koostuvat nesteestä ja kiintoaineksesta. Tällaisia jätteitä ovat esimerkiksi hiekan- ja rasvanerotuskaivoista imetyt nesteet sekä teollisuudessa syntyvät jätevesilietteet. Nestemäisiä jätteitä ei ole Valtioneuvoston päätöksestä enää vuoden 2002 jälkeen saanut sijoittaa sellaisenaan kaatopaikkapenkkaan, vaan ne on tullut esikäsitellä nesteen poistamiseksi. Tähän asti nestemäiset jätteet on käsitelty Tarastenjärven jätekeskuksessa painovoimaisesti erottelemalla. Menetelmä on ollut toimiva, mutta on päivityksen tarpeessa. Tämän opinnäytetyön tarkoituksena olikin tutkia erilaisia vaihtoehtoja nestemäisten jätteiden vastaanotolle sekä käsittelylle Tarastenjärven jätekeskuksessa, sekä arvioida eri vaihtoehtojen kustannuksia mikäli mahdollista. Myös tarvetta haitta-aineiden, kuten metallien ja öljyjen poistamiselle tutkittiin. Työn laatimisessa hyödynnettiin olemassa olevaa tieteellistä kirjallisuutta sekä asiantuntijahaastatteluja. Työn tilaajana toimi Pirkanmaan Jätehuolto Oy. Selvitystyön tuloksena kävi ilmi, että yleisimmät menetelmät nesteiden ja kiinteiden ainesten erottamiseen ovat painovoimainen erottelu ja suodatus. Painovoimaiset erottelijat ovat useimmiten kiinteäseinäisiä altaita, joissa kiintoaines laskeutuu painovoimaisesti altaan pohjalle ja pinnalle jäänyt kirkastunut neste ohjataan ylivuotona jatkokäsittelyyn. Kiintoaineksen ollessa kevyempää kuin vesi, se erottuu nesteen pinnalle. Suodattimien toiminta taas perustuu puoliläpäisevään suodatusmediaan, joka päästää nesteen läpi, mutta jättää kiintoaineksen suodattimeen. Suodattimet voivat olla esimerkiksi paineistettuja tai painovoimalla toimivia. Geotuubit ovat eräänlaisia paineistettuja säkkisuodattimia, joita on käytössä myös jätekeskuksissa. Useissa käsittelymenetelmissä käytetään apuna myös saostuskemikaaleja, jotka edistävät kiintoaineksen erottumista nesteestä. Haitta-aineiden osalta helpoin ratkaisu on poistaa ne kiintoaineksen mukana ja käsitellä ne pilaantuneiden maiden kanssa jätekeskuksessa. Mikäli haitta-aineet ovat nesteessä liukoisessa muodossa, voidaan apuna käyttää saostuskemikaaleja, kuten alumiini- tai rautasuoloja. Öljyjen erottamisessa olisi mahdollista hyödyntää öljynerotuskaivoa. Kirjallisuuden sekä haastattelujen perusteella päivitetty versio painovoimaisesta erottelujärjestelmästä sekä geotuubimenetelmä vaikuttavat parhailta käytettävissä olevilta ratkaisuilta. Suurin haaste jätekeskuksen nestemäisten jätteiden käsittelyssä on kuitenkin se, että nesteiden ominaisuudet eroavat kuormittain hyvin paljon toisistaan. Tähän voitaisiin vaikuttaa jätteiden tarkemmalla lajittelulla vastaanottovaiheessa. Käsittelymenetelmää valittaessa tulee kuitenkin pohtia järjestelmän kuluja sekä hyötyjä pitkällä aikavälillä niin, että päästään parhaaseen mahdolliseen puhdistuslopputulokseen.Liquid wastes are solid-liquid mixtures such as wastes from sand and grease separation wells and industrial wastewaters. Since 2002 liquid wastes have no longer been allowed to be placed at a waste disposal site according to the decree 1049/1999 of the Finnish Council of State. Therefore liquid wastes have to be dewatered before final disposal. At the moment liquid wastes are treated at the Tarastenjärvi waste management centre with gravitational separation but the system needs updating. The aim of this study was to provide Pirkanmaan Jätehuolto Oy with different methods of liquid waste handling as well as evaluate the costs of a new system if possible. Also the need for contaminant removal was taken into consideration. The study was carried out by literature reviews and interviewing professionals of the industry. The results showed that the most common methods of solid-liquid separation are gravitational separation and filtration. Gravitational separators are usually containers in which the solid matter is allowed to separate either by sedimentation or flotation. Filters have a semi-permeable filter media which traps the solid matter but allows the liquid to flow through. Geotubes are an example of filters that are currently being used in several waste management centres. Many separation methods also require the use of polymers or flocculants to operate effectively. When contaminants are in a settleable form they are rather easy to be removed and treated with the solid matter. If the contaminants are dissolved in the liquid it might be possible to make them settle by adding aluminium or iron sulphate. Also an oil separation well could be used to separate oils from the liquid phase. Based on the literature reviews and interviews an upgraded gravitational system or the geotube method seem to be the best options. However, more tests should be conducted to see if these methods would work in practice. The biggest challenge is that the incoming liquid waste loads at Tarastenjärvi are not homogenous which makes it difficult to choose a solution that works well for all of them. The situation could be improved with more precise classification of the waste loads and handling them separately according to their characteristics. The most important aspect is to find a long-term cost-effective solution that can provide sufficient handling of the liquid wastes

Standard Operating Procedure - Collaborative Spatial Assessment CoSA - Release 1.0

The purpose of this Standard Operating Procedure (SOP) is to establish uniform procedures pertaining to the preparation for, the performance of, and the reporting of COllaborative (geo) Spatial Assessment (CoSA). CoSA provides a synoptic, unbiased assessment over the impact area of a disaster, which feeds the two main recovery perspectives of the Post-Disaster Needs Assessment (PDNA): i) the valuation of damages and losses carried out through the Damage and Loss Assessment (DaLA) methodology; and ii) the identification of human impacts and recovery needs carried out though the Human Recovery Needs Assessment (HRNA). CoSA is distinct from other geospatial and remote sensing based assessments because it i) draws on the collaborative efforts of distributed capacities in remote sensing and geospatial analysis, ii) aims to achieve the highest possible accuracy in line with the requirements of the PDNA and iii) tries to do so under stringent timing constraints set by the PDNA schedule. The current SOP will aid in ensuring credibility, consistency, transparency, accuracy and completeness of the CoSA. It is a living document, however, that will be enriched with new practical experiences and regularly updated to incorporate state-of-the-art procedures and new technical developments.JRC.DG.G.2-Global security and crisis managemen

Optical fiber‐based in vivo quantification of growth factor receptors

BACKGROUND: Growth factor receptors such as epidermal growth factor receptor 1 and human epidermal growth receptor 2 (HER2) are overexpressed in certain cancer cells. Antibodies against these receptors (eg. cetuximab and transtuzumab [Herceptin]) have shown therapeutic value in cancer treatment. The existing methods for the quantification of these receptors in tumors involve immunohistochemistry or DNA quantification, both in extracted tissue samples. The goal of the study was to evaluate whether an optical fiber‐based technique can be used to quantify the expression of multiple growth factor receptors simultaneously. METHODS: The authors examined HER2 expression using the monoclonal antibody trastuzumab as a targeting ligand to test their system. They conjugated trastuzumab to 2 different Alexa Fluor dyes with different excitation and emission wavelengths. Two of the dye conjugates were subsequently injected intravenously into mice bearing HER2‐expressing subcutaneous tumors. An optical fiber was then inserted into the tumor through a 30‐gauge needle, and using a single laser beam as the excitation source, the fluorescence emitted by the 2 conjugates was identified and quantified by 2‐photon optical fiber fluorescence. RESULTS: The 2 conjugates bound to the HER2‐expressing tumor competitively in a receptor‐specific fashion, but they failed to bind to a similar cell tumor that did not express HER2. The concentration of the conjugate present in the tumor as determined by 2‐photon optical fiber fluorescence was shown to serve as an index of the HER2 expression levels. CONCLUSIONS: These studies offer a minimally invasive technique for the quantification of tumor receptors simultaneously. Cancer 2012;. © 2011 American Cancer Society. The paper describes the in vivo quantification of human epidermal growth receptor 2 using a minimally invasive 2‐photon optical fiber fluorescence detection technique. The proof of concept for the simultaneous in vivo quantification of multiple receptors is provided.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91221/1/26487_ftp.pd

Modelling chemistry in the nocturnal boundary layer above tropical rainforest and a generalised effective nocturnal ozone deposition velocity for sub-ppbv NOx conditions

Measurements of atmospheric composition have been made over a remote rainforest landscape. A box model has previously been demonstrated to model the observed daytime chemistry well. However the box model is unable to explain the nocturnal measurements of relatively high [NO] and [O3], but relatively low observed [NO2]. It is shown that a one-dimensional (1-D) column model with simple O3 -NOx chemistry and a simple representation of vertical transport is able to explain the observed nocturnal concentrations and predict the likely vertical profiles of these species in the nocturnal boundary layer (NBL). Concentrations of tracers carried over from the end of the night can affect the atmospheric chemistry of the following day. To ascertain the anomaly introduced by using the box model to represent the NBL, vertically-averaged NBL concentrations at the end of the night are compared between the 1-D model and the box model. It is found that, under low to medium [NOx] conditions (NOx <1 ppbv), a simple parametrisation can be used to modify the box model deposition velocity of ozone, in order to achieve good agreement between the box and 1-D models for these end-of-night concentrations of NOx and O3. This parametrisation would could also be used in global climate-chemistry models with limited vertical resolution near the surface. Box-model results for the following day differ significantly if this effective nocturnal deposition velocity for ozone is implemented; for instance, there is a 9% increase in the following day’s peak ozone concentration. However under medium to high [NOx] conditions (NOx > 1 ppbv), the effect on the chemistry due to the vertical distribution of the species means no box model can adequately represent chemistry in the NBL without modifying reaction rate constants