2,078 research outputs found
ERISA: A Co-Fiduciary Has No Right to Contribution and Indemnity
Because retirement plans involve large amounts of money, large numbers of people, and fiduciaries with conflicts of interests, Congress designed ERISA to differ from traditional trust law to meet these specific needs and important policy concerns. Before ERISA, fiduciaries and employers often manipulated lack of oversight and conflict of interests to the detriment of the beneficiaries. ERISA raised the standards owed by fiduciaries and established a policing system that required professional fiduciaries to monitor non-professional fiduciaries, thereby forcing non-professional fiduciaries to leave the field or seek expert advice. These provisions created co-fiduciary liability by imputing the liability of the co-fiduciary to an innocent fiduciary and in general creating an atmosphere of transparency and security.
Congress considered the possibility of contribution and indemnity in two limited applications. First, exculpation provisions under ERISA generally banned indemnity except in limited circumstances. Second, insurance provisions allowed a type of contribution, if the plan paid the premiums. The Supreme Court has remained true to the Congressional scheme and denied court implied contribution and indemnity. Parties to private pension plans have the power to specify the plan terms as set forth in ERISA and may allocate liabilities amongst themselves. If they choose not to change the terms, then the intent and purpose of ERISA should control the interpretation of the plan and the fiduciaries responsibilities of the plan
Descriptive Analysis of Common Functional Limitations Identified by Patients with Shoulder Pain
Context: Recent establishment of G-codes by the US government requires therapists to report function limitations at initial evaluation. Limited information exists specific to the most common limitations in patients with shoulder pain.
Objective: To describe the most commonly expressed shoulder limitations with activities and their severity/level of impairment from a patient’s perspective on the initial evaluation.
Design: Descriptive.
Setting: Patients reporting pain with overhead activity and seeking medical attention from one orthopedic surgeon were recruited as part of a cohort study.
Patients: 176 with shoulder superior labral tear from anterior to posterior (SLAP), subacromial impingement, combined SLAP and rotator cuff, and nonspecific (female = 53, age = 41 ± 13 y; male = 123, age = 41 ± 12 y).
Interventions: Data were obtained on the initial visit from the Patient-Specific Functional Scale (PSFS) questionnaire. Three researchers extracted meaningful concepts from the PSFS and linked them to the International Classification of Functioning (ICF) categories according to established ICF linking rules.
Results: 176 participants yielded 765 meaningful concepts that were linked to the ICF with a 66% agreement between researchers before consensus. There were no differences between diagnoses. Of all patients, 88% reported functional limitations coded into meaningful concepts as represented by 10 ICF codes; 634 (83%) meaningful concepts were linked to the activities and participation domain while 129 (17%) were linked to the body function domain. Only 2 reported functional limitations that were considered nondefinable (nd). The overall average initial impairment score on the PSFS = 4 ± 2.5 out of 10 points.
Conclusion: Meaningful concepts from the activities and participation domain were most commonly identified as functional limitations and were more prevalent than limitations from the body function domain. This information helps identify some of the most common limitations in patients with shoulder pain that therapists can use to efficiently document patient functional impairment
High Dose, Variable Length, N-acetylcysteine (HINAC) Therapy for Late-presenting Acetaminophen Poisoning
N-body simulations of the Magellanic Stream
A suite of high-resolution N-body simulations of the Magellanic Clouds --
Milky Way system are presented and compared directly with newly available data
from the HI Parkes All-Sky Survey (HIPASS). We show that the interaction
between Small and Large Magellanic Clouds results in both a spatial and
kinematical bifurcation of both the Stream and the Leading Arm. The spatial
bifurcation of the Stream is readily apparent in the HIPASS data, and the
kinematical bifurcation is also tentatively identified. This bifurcation
provides strong support for the tidal disruption origin for the Magellanic
Stream. A fiducial model for the Magellanic Clouds is presented upon completion
of an extensive parameter survey of the potential orbital configurations of the
Magellanic Clouds and the viable initial boundary conditions for the disc of
the Small Magellanic Cloud. The impact of the choice of these critical
parameters upon the final configurations of the Stream and Leading Arm is
detailed.Comment: Accepted by MNRAS, 07 Jun 2006. 14 pages, 14 figures, 3 tables. LaTeX
(mn2e.sty). File with decent resolution images (strongly recommended)
available at http://astronomy.swin.edu.au/~tconnors/publications/ .
References added; distance and HI-LOres difference figures added; clearer
figures; discussion added to, but conclusions unchange
NEXUS/Physics: An interdisciplinary repurposing of physics for biologists
In response to increasing calls for the reform of the undergraduate science
curriculum for life science majors and pre-medical students (Bio2010,
Scientific Foundations for Future Physicians, Vision & Change), an
interdisciplinary team has created NEXUS/Physics: a repurposing of an
introductory physics curriculum for the life sciences. The curriculum interacts
strongly and supportively with introductory biology and chemistry courses taken
by life sciences students, with the goal of helping students build general,
multi-discipline scientific competencies. In order to do this, our two-semester
NEXUS/Physics course sequence is positioned as a second year course so students
will have had some exposure to basic concepts in biology and chemistry.
NEXUS/Physics stresses interdisciplinary examples and the content differs
markedly from traditional introductory physics to facilitate this. It extends
the discussion of energy to include interatomic potentials and chemical
reactions, the discussion of thermodynamics to include enthalpy and Gibbs free
energy, and includes a serious discussion of random vs. coherent motion
including diffusion. The development of instructional materials is coordinated
with careful education research. Both the new content and the results of the
research are described in a series of papers for which this paper serves as an
overview and context.Comment: 12 page
FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I–induced DNA breakage and transcriptional stress
FUS (fused in sarcoma) plays a key role in several steps of RNA metabolism, and dominant mutations in this protein are associated with neurodegenerative diseases. Here, we show that FUS is a component of the cellular response to topoisomerase I (TOP1)–induced DNA breakage; relocalising to the nucleolus in response to RNA polymerase II (Pol II) stalling at sites of TOP1-induced DNA breaks. This relocalisation is rapid and dynamic, reversing following the removal of TOP1-induced breaks and coinciding with the recovery of global transcription. Importantly, FUS relocalisation following TOP1-induced DNA breakage is associated with increased FUS binding at sites of RNA polymerase I transcription in ribosomal DNA and reduced FUS binding at sites of RNA Pol II transcription, suggesting that FUS relocates from sites of stalled RNA Pol II either to regulate pre-mRNA processing during transcriptional stress or to modulate ribosomal RNA biogenesis. Importantly, FUS-mutant patient fibroblasts are hypersensitive to TOP1-induced DNA breakage, highlighting the possible relevance of these findings to neurodegeneration
Authigenic carbonates from the Cascadia subduction zone and their relation to gas hydrate stability
Authigenic carbonates are intercalated with massive gas hydrates in sediments of the Cascadia margin. The deposits were recovered from the uppermost 50 cm of sediments on the southern summit of the Hydrate Ridge during the RV Sonne cruise SO110. Two carbonate lithologies that differ in chemistry, mineralogy, and fabric make up these deposits. Microcrystalline high-magnesium calcite (14 to 19 mol% MgCO3) and aragonite are present in both semiconsolidated sediments and carbonate-cemented clasts. Aragonite occurs also as a pure phase without sediment impurities. It is formed by precipitation in cavities as botryoidal and isopachous aggregates within pure white, massive gas hydrate. Variations in oxygen isotope values of the carbonates reflect the mineralogical composition and define two end members: a Mg-calcite with δ18O =4.86‰ PDB and an aragonite with δ18O =3.68‰ PDB. On the basis of the ambient bottom-water temperature and accepted equations for oxygen isotope fractionation, we show that the aragonite phase formed in equilibrium with its pore-water environment, and that the Mg-calcite appears to have precipitated from pore fluids enriched in 18O. Oxygen isotope enrichment probably originates from hydrate water released during gas-hydrate destabilization
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