Desmineralização e dessulfitação, por resinas intercambiadoras de íons, de mostos sulfitados

A comparison was made of ability of four ion exchange resins to remove sulfur dioxide, iron and potassium from sulfited musts. The resins used were Lewatit S 100 and MP 62 and Amberlite IR-120 and IR-45. The Lewatit MP 62 resin proved unsuitable for this purpose because it decolorized the must. Amberlite IR-120 and IR-45, removed 62-92% of the iron, 80-93% of the potassium, 50-59% of the free sulfur dioxide and 27-41% of the total sulfur dioxide without affecting the colour.Foram experimentadas as resinas Lewatit S 100 (catiônica) e MP 62 (aniônica) e Amberlite IR-120 (catiônica) e IR-45 (aniônica) no tratamento de mostos sulfitados, com a finalidade de eliminar o ferro, o potássio e, principalmente, o anidrido sulfuroso. As resinas Lewatit S 100 e MP 62 revelaram-se impróprias para esta finalidade, por tirarem quase completamente a cor do mosto. Resultaram apropriadas as resinas Amberlite IR-120 e IR-45, que eliminaram 62-92% do ferro, 80-93% do potássio, 50-59% do anidrido sulfuroso livre, e 27-41% do anidrido sulfuroso total, sem influir sensivelmente sobre a cor dos mostos sulfitados

Teores de nitrogênio total e proteico em mostos brancos

The total and protein nitrogen contents in white musts of the 1972 and 1973 vintages of Bento Gonçalves, Rio Grande do Sul, Brazil, were investigated. Of the 50 musts from the 1972 vintage examined, the total nitrogen content varied from 56.8 to 326.0 mg per liter, with a mean of 174.7 mg per liter. In the same year, the protein nitrogen content varied from 8.4 to 34.4 mg per liter. Of the 97 musts from the 1973 vintage examined, the total nitrogen content varied from 85.8 to 436,8 mg per liter, with a mean of 210.9 mg per liter. In the same year, the protein nitrogen content varied from 11.2 to 43.9 mg per liter.Foram pesquisados os teores de nitrogênio total e proteico de mostos brancos do município de Bento Gonçalves, RS, durante os anos de 1972 e 1973. Em 1972, nos 50 mostos examinados, o teor em nitrogênio total  variou de 56,8 a 326,0 mg/litro, sendo o teor médio resultante de 174,7 mg/litro. No mesmo ano, o teor de nitrogênio proteico variou de 8,4 a 34,4 mg/litro. Em 1973, nos 97 mostos examinados, o teor de nitrogênio total variou de 85,8 a 436,8 mg/litro, resultando o teor médio de 210,9 mg/litro. Ainda neste ano, o teor de nitrogênio proteico variou de 11,2 a 43,9 mg/litro

Estudo analítico dos sucos de uva comerciais

Twelve commercial grape juices, representing the majority of grape juices presentely marketed in Brazil, were analysed. With reference to the "Standards of Identity and Quality of Crape Juices" established by the National Commission for Food Norms and Standards (CNNPA), it was established that: a) two grape juices contained an iron content higher than 15 mg per liter, the maximum content permitted and b) five grape juices contained a sulfur dioxide content higher than 200 mg per liter, the maximum content permitted.Foram analisados 12 sucos de uva comerciais, representando a quase totalidade dos atualmente comercializados no Brasil. Tomando por base de julgamento os “Padrões de Identidade e Qualidade de Sucos de Uva", estabelecidos pela Comissão Nacional de Normas e Padrões Alimentares (CNNPA), constatou-se que: a) dois dos 12 sucos apresentaram teor em ferro superior a 15 mg/l, teor máximo admitido; b) cinco, dos 12 sucos, apresentaram teor em SO2 superior a 200 mg/l, teor máximo admitido

Salivary biomarkers for diagnosis of systemic diseases and malignant tumors. A systematic review

Saliva evaluation could be a possible alternative to blood and/or tissue analyses, for researching specific molecules associated to the presence of systemic diseases and malignancies. The present systematic review has been designed in order to answer to the question ?are there significant associations between specific salivary biomarkers and diagnosis of systemic diseases or malignancies??. The Preferred Reporting Item for Systematic Reviews and Meta-analysis (PRISMA) statement was used to guide the review. The combinations of ?saliva? and ?systemic diseases? or ?diagnosis? or ?biomarkers? or ?cancers? or ?carcinoma? or ?tumors?, were used to search Medline, Scopus and Web of Science databases. Endpoint of research has been set at May 2019. Studies were classified into 3 groups according to the type of disease investigated for diagnosis: 1) malignant tumors; 2) neurologic diseases and 3) inflammatory/metabolic/cardiovascular diseases. Assessment of quality has been assigned according to a series of questions proposed by the National Institute of Health. Level of evidence was assessed using the categories proposed in the Oxford Center for Evidence-Based medicine (CEMB) levels for diagnosis (2011). Seventy-nine studies met the inclusion and exclusion criteria. Fifty-one (64%) investigated malignant tumors, 14 (17.5%) neurologic and 14 (18.5%) inflammatory/cardiovascular/metabolic diseases. Among studies investigating malignant tumors, 12 (23.5%) were scored as ?good? and 11 of these reported statistically significant associations between salivary molecules and pathology. Two and 5 studies were found to have a good quality, among those evaluating the association between salivary biomarkers and neurologic and inflammatory/metabolic/cardiovascular diseases, respectively. The present systematic review confirms the existence of some ?good? quality evidence to support the role of peculiar salivary biomarkers for diagnosis of systemic diseases (e.g. lung cancer and EGFR)

Salivary microRNA for diagnosis of cancer and systemic diseases: A systematic review

Background: The aberrant expression of microRNAs (miRNAs) has been associated with several diseases, including cancer, inflammatory, and autoimmune conditions. Interest in salivary miRNAs as non-invasive tools for the diagnosis of malignancies and systemic diseases is rapidly increasing. The present systematic review was developed for answering the question: \u201cAre salivary microRNAs reliable biomarkers for diagnosis of cancer and systemic diseases?\u201d Methods: The application of inclusion and exclusion criteria led to the selection of 11 papers. Critical appraisals and quality assessments of the selected studies were performed through the National Institute of Health \u201cStudy Quality Assessment Tool\u201d and the classification of the Oxford Center for Evidence-Based Medicine. Results: Seven studies reported statistically significant correlations between one or more salivary miRNAs and the investigated disease. The critical analysis allowed us to classify only two studies (18.2%) as having \u201cgood\u201d quality, the rest being scored as \u201cintermediate\u201d (8; 73%) and \u201cpoor\u201d (1; 9%). Evidence exists that salivary miR-940 and miR-3679-5p are reliable markers for pancreatic cancer and that miR140-5p and miR301a are promising molecules for the salivary diagnosis of gastric cancer. Conclusions: Further studies, possibly avoiding the risk of bias highlighted here, are necessary to consolidate these findings and to identify new reliable salivary biomarkers

Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines

It is well known that resveratrol (RSV) displayed cancer-preventing and anticancer properties but its clinical application is limited because of a low bioavailability and a rapid clearance from the circulation. Aim of this work was to synthesize pharmacologically active resveratrol analogs with an enhanced structural rigidity and bioavailability. In particular, we have synthesized a library of 2,3-thiazolidin-4-one derivatives in which a thiazolidinone nucleus connects two aromatic rings. Some of these compounds showed strong inhibitory effects on breast cancer cell growth. Our results indicate that some of thiazolidin-based resveratrol derivatives may become a new potent alternative tool for the treatment of human breast cancer

Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe