High fatigue scores before and after surgical treatment of bone and soft tissue tumors

Item does not contain fulltextThe first objective of the present study was to investigate fatigue severity in patients diagnosed with bone and soft tissue tumors prior to the surgical treatment of the tumor and 6 months post-operatively. The second objective was to determine which variables are associated with severe fatigue. Patients diagnosed with benign or low-grade malignant bone and soft tissue tumors, undergoing surgical therapy for the tumor only, were included in this study. The control group contained patients scheduled for knee arthroscopy for suspected meniscus tears. Fatigue, pain, anxiety and self-efficacy were measured pre-operatively and after 6 months and each patient wore an actometer to quantify physical activity. In the tumor group of 43 patients, 35% were severely fatigued pre-operatively and 33% post-operatively. The tumor group reported a significantly higher level of anxiety. No differences were observed in pain, physical limitations, self-efficacy or actometer scores. Multiple regression analysis of the tumor group revealed that higher pain scores, higher state anxiety and lower self-efficacy were asssociated with fatigue severity. In the control group of 24 knee arthroscopy patients, the percentage of severely fatigued patients decreased from 38% (n=9) prior to treatment to 29% (n=7) 6 months later. A substantial number of patients were severely fatigued in both the tumor group and the knee arthroscopy group. Self-efficacy, pain and anxiety appear to be the most important variables associated with fatigue severity in tumor patients prior to surgery

Teaching of Energy Issues: A debate proposal for a GLobal Reorientation

The growing awareness of serious difficulties in the learning of energy issues has produced a great deal of research, most of which is focused on specific conceptual aspects. In our opinion, the difficulties pointed out in the literature are interrelated and connected to other aspects (conceptual as well as procedural and axiological), which are not sufficiently taken into account in previous research. This paper aims to carry out a global analysis in order to avoid the more limited approaches that deal only with individual aspects. From this global analysis we have outlined 24 propositions that are put forward for debate to lay the foundations for a profound reorientation of the teaching of energy topics in upper high school courses, in order to facilitate a better scientific understanding of these topics, avoid many students' misconceptions and enhance awareness of the current situation of planetary emergency

Measurement of the Ξ^-_b and Ω^-_b baryon lifetimes

Using a data sample of pp collisions corresponding to an integrated luminosity of $3~ \rm fb^{-1}$, the $\Xi_b^-$ and $\Omega_b^-$ baryons are reconstructed in the $\Xi_b^- \rightarrow J/\psi \Xi^-$ and $\Omega_b^- \rightarrow J/\psi \Omega^-$ decay modes and their lifetimes measured to be \tau (\Xi_b^-) = 1.55\, ^{+0.10}_{-0.09}~{\rm(stat)} \pm 0.03\,{\rm(syst)} ps, \tau (\Omega_b^-) = 1.54\, ^{+0.26}_{-0.21}~{\rm(stat)} \pm 0.05\,{\rm(syst)} ps. These are the most precise determinations to date. Both measurements are in good agreement with previous experimental results and with theoretical predictions

First observation and amplitude analysis of the B−→D+K−π− decay

The B−→D+K−π− decay is observed in a data sample corresponding to 3.0  fb−1 of pp collision data recorded by the LHCb experiment during 2011 and 2012. Its branching fraction is measured to be B(B−→D+K−π−)=(7.31±0.19±0.22±0.39)×10−5 where the uncertainties are statistical, systematic and from the branching fraction of the normalization channel B−→D+π−π−, respectively. An amplitude analysis of the resonant structure of the B−→D+K−π− decay is used to measure the contributions from quasi-two-body B−→D∗0(2400)0K−, B−→D∗2(2460)0K−, and B−→D∗J(2760)0K− decays, as well as from nonresonant sources. The D∗J(2760)0 resonance is determined to have spin 1

First observation and amplitude analysis of the B- -> D+K-pi(-) decay

The B-→D+K-π- decay is observed in a data sample corresponding to 3.0 fb-1 of pp collision data recorded by the LHCb experiment during 2011 and 2012. Its branching fraction is measured to be B(B-→D+K-π-)=(7.31±0.19±0.22±0.39)×10-5 where the uncertainties are statistical, systematic and from the branching fraction of the normalization channel B-→D+π-π-, respectively. An amplitude analysis of the resonant structure of the B-→D+K-π- decay is used to measure the contributions from quasi-two-body B-→D0∗(2400)0K-, B-→D2∗(2460)0K-, and B-→DJ∗(2760)0K- decays, as well as from nonresonant sources. The DJ∗(2760)0 resonance is determined to have spin 1

Measurement of the Difference of Time-Integrated CPAsymmetries in D0→K−K+ and D0→π−π+ Decays

A search for CP violation in $D^0 \rightarrow K^{-} K^{+}$ and $D^0 \rightarrow \pi^{-} \pi^{+}$ decays is performed using $pp$ collision data, corresponding to an integrated luminosity of $3~fb^{-1}$, collected using the LHCb detector at centre-of-mass energies of 7 and $8~$TeV. The flavour of the charm meson is inferred from the charge of the pion in $D^{*+}\rightarrow D^0\pi^+$ and $D^{*-}\rightarrow \bar{D^0}\pi^{-}$ decays. The difference between the CP asymmetries in $D^0 \rightarrow K^{-} K^{+}$ and $D^0 \rightarrow \pi^{-} \pi^{+}$ decays, $\Delta A_{CP} \equiv A_{CP}(K^{-} K^{+}) - A_{CP}(\pi^{-} \pi^{+})$, is measured to be $\left( -0.10 \pm 0.08(stat) \pm 0.03(syst) \right) \%$. This is the most precise measurement of a time-integrated CP asymmetry in the charm sector from a single experiment.Comment: All figures and tables, along with any supplementary material and additional information, are available at http://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2015-055.htm

Dalitz plot analysis ofB0→D¯0π+π−decays

The resonant substructures of $B^0 \to \overline{D}^0 \pi^+\pi^-$ decays are studied with the Dalitz plot technique. In this study a data sample corresponding to an integrated luminosity of 3.0 fb$^{-1}$ of $pp$ collisions collected by the LHCb detector is used. The branching fraction of the $B^0 \to \overline{D}^0 \pi^+\pi^-$ decay in the region $m(\overline{D}^0\pi^{\pm})>2.1$ GeV$/c^2$ is measured to be $(8.46 \pm 0.14 \pm 0.29 \pm 0.40) \times 10^{-4}$, where the first uncertainty is statistical, the second is systematic and the last arises from the normalisation channel $B^0 \to D^*(2010)^-\pi^+$. The $\pi^+\pi^-$ S-wave components are modelled with the Isobar and K-matrix formalisms. Results of the Dalitz plot analyses using both models are presented. A resonant structure at $m(\overline{D}^0\pi^-) \approx 2.8$ GeV$/c^{2}$ is confirmed and its spin-parity is determined for the first time as $J^P = 3^-$. The branching fraction, mass and width of this structure are determined together with those of the $D^*_0(2400)^-$ and $D^*_2(2460)^-$ resonances. The branching fractions of other $B^0 \to \overline{D}^0 h^0$ decay components with $h^0 \to \pi^+\pi^-$ are also reported. Many of these branching fraction measurements are the most precise to date. The first observation of the decays $B^0 \to \overline{D}^0 f_0(500)$, $B^0 \to \overline{D}^0 f_0(980)$, $B^0 \to \overline{D}^0 \rho(1450)$, $B^0 \to D_3^*(2760)^- \pi^+$ and the first evidence of $B^0 \to \overline{D}^0 f_0(2020)$ are presented.Comment: 64 pages, 17 figure