EFFECT OF PLANTING DATES AND FREQUENCIES OF INTERCROPPING ON YIELD AND INCOME OF BEAN AND BANANA

EFFECT OF PLANTING DATES AND FREQUENCIES OF INTERCROPPING ON YIELD AND INCOME OF BEAN AND BANAN

Adenopatía inguinal a estudio: ¿debemos incluir siempre el linfogranuloma venéreo en el diagnóstico diferencial?

Lymphogranuloma venereum is a disease with a significant increase in prevalence in Spain in recent years, so it must be taken into account in the screening of sexually transmitted diseases. In this case, a patient with the presence of a unilateral inguinal adenopathy that denied risky sexual relations is shown. After the histological study of the adenopathy, which shows granulomatosis, and discarding tuberculosis, among other entities, Chlamydia trachomatis serology was requested, being positive, with a good clinical and serological response to the treatment.El linfogranuloma venéreo es una enfermedad con un importante aumento de prevalencia en España en los últimos años, de forma que debe tenerse en cuenta en el cribado de enfermedades de transmisión sexual. En este caso, se muestra un paciente con presencia únicamente de una adenopatía inguinal unilateral que negaba relaciones sexuales de riesgo. Tras el estudio histológico de la adenopatía, que mostraba granulomatosis, y tras descartar tuberculosis, entre otras entidades, se solicitó serología de Chlamydia trachomatis, que resultó positiva, con buena respuesta clínica y serológica al tratamiento.

Avaliação do componente bucal. : Projeto “Escolas Saudáveis” da Fundação Las Golondrinas, Medellín, 2006-2011

Introduction: We aim to assess a health education strategy for schools, regarding the oral component, through oral hygiene and oral health indexes, using the knowledge and practices for oral health of school kids, parents and/or significant adults. Methods: We conducted an evaluation using elements from a quantitative and descriptive study in two periods, 2006 and 2011. We carried out a review of dental records and clinical examinations using oral hygiene (IHOs) and oral health (DMFT and deft) indexes. A survey was conducted in school kids, parents and/or significant adults about knowledge and practices relevant to oral health. Results: We found an improvement of the knowledge and practices relating to oral health in the participants of the study. Parents and adults noticed a positive change in the oral health of children. A positive change in the oral hygiene was found in 56% of females, 54% of children under 11 and 53% of the high school students. 60% of the children were healthy relative to cavities at the time of examination and 44% had no caries experience. Conclusions: The observed indicators allowed us to positively evaluate the results of the project and invited to strengthening community strategies for health education within institutional plans.Introducción: se pretende evaluar una estrategia de escuela saludable en su componente bucal a través de indicadores de higiene bucal, salud bucal y conocimientos y prácticas de diversos actores (escolares y padres o adultos significativos). Métodos: estudio evaluativo a través de elementos de un estudio cuantitativo y descriptivo con datos de dos momentos del tiempo (2006 y 2011). Se revisaron historias clínicas y se realizaron exámenes clínicos para indicadores de higiene bucal (iho) y salud bucal (cop-d, ceo-d). Encuesta a padres o adultos significativos, y a escolares, sobre conocimientos y prácticas en salud bucal. Resultados: existe mejoría en los conocimientos y prácticas de los escolares partícipes del desarrollo del proyecto, haciéndose visible para los adultos que notan un cambio positivo en la salud bucal de los niños. Se presentó un cambio positivo en la higiene bucal del 56% de las mujeres, del 54% de los niños y niñas menores de 11 años y del 53% de los estudiantes de secundaria. Se encontró para el 2011 que el 60% estaba sano en el momento del examen y un 44% no tenía experiencia de caries. Conclusiones: los indicadores observados permitieron evaluar positivamente los resultados del proyecto, y se invita al fortalecimiento de estrategias comunitarias desde la educación para la salud en los planes educativos institucionales.Introdução: pretende-se avaliar uma estratégia de escola saudável em seu componente bucal por meio de indicadores de higiene bucal, saúde bucal e conhecimentos e práticas de diversos autores (escolares e pais ou adultos significativos). Métodos: estudo avaliativo mediante elementos de um estudo quantitativo e descritivo com dados de dois momentos: 2006 e 2011. Revisaram-se histórias clínicas e realizaram-se exames clínicos para indicadores de higiene bucal (IHOS) e saúde bucal (cop-d, ceo-d). Enquete a pais ou adultos significativos e a escolares sobre conhecimentos e práticas em saúde bucal. Resultados: existe uma melhoria nos conhecimentos e práticas dos escolares participantes do desenvolvimento do projeto, fazendo-se visível para os adultos que notam uma mudança positiva na saúde bucal das crianças. Apresentou-se uma mudança positiva na higiene bucal de 56% das mulheres, de 54% das crianças menores de 11 anos e de 53% dos estudantes do ensino fundamental (a partir da sexta série). Constatou-se para 2011 que 60% estavam saudáveis no momento do exame e 44% não tinham experiência de cáries. Conclusões: os indicadores observados permitiram avaliar positivamente os resultados do projeto, e convida ao fortalecimento de estratégias comunitárias a partir da educação para a saúde nos planos educativos institucionais

Visiones transversales de Puerto Rico y el Caribe

Con autorización de la editorial para este libro. La edición del libro estuvo a cargo de Beatriz Cruz Sotomayor y Félix R. Huertas González.Visiones transversales de Puerto Rico y el Caribe es producto de un proyecto internacional de investigación en el que han venido participando, por los pasados años, un grupo de historiadores y especialistas de diversas disciplinas en el área de los estudios caribeños. Como lo sugiere su título, el libro apuesta a la transversalidad como enfoque que permite explorar, desde múltiples perspectivas, la diversidad que ya de por sí implica la región caribeña y, en particular, la isla de Puerto Rico. Este persigue innovar en su metodología, marcos teóricos, perspectivas críticas y en una rica variedad de campos de estudio sobre Puerto Rico en el contexto del Caribe. Desde una diversidad de análisis, los ensayos transitan también un amplio espectro temático: esclavitud, urbanismo, ambiente, identidad, cultura, diáspora, economía, arte, literatura y política, entre otros.Connected Worlds: The Caribbean, Origin of the Modern World. Este proyecto ha recibido fondos del programa de investigación e innovación Horizon 2020 de la Unión Europea en virtud del acuerdo de subvención Marie Sklodowska-Curie Nº 823846. El proyecto está dirigido por la profesora Consuelo Naranjo Orovio del Instituto de Historia-CSIC.Peer reviewe

Correction : Chaparro et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J. Clin. Med. 2021, 10, 2885

The authors wish to make the following corrections to this paper [...]

Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain : Large-Scale Epidemiological Study

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery

Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy:Study protocol of a cluster randomized clinical trial (Multi-PAP project)

This study was funded by the Fondo de Investigaciones Sanitarias ISCIII (Grant Numbers PI15/00276, PI15/00572, PI15/00996), REDISSEC (Project Numbers RD12/0001/0012, RD16/0001/0005), and the European Regional Development Fund ("A way to build Europe").Background: Multimorbidity is associated with negative effects both on people's health and on healthcare systems. A key problem linked to multimorbidity is polypharmacy, which in turn is associated with increased risk of partly preventable adverse effects, including mortality. The Ariadne principles describe a model of care based on a thorough assessment of diseases, treatments (and potential interactions), clinical status, context and preferences of patients with multimorbidity, with the aim of prioritizing and sharing realistic treatment goals that guide an individualized management. The aim of this study is to evaluate the effectiveness of a complex intervention that implements the Ariadne principles in a population of young-old patients with multimorbidity and polypharmacy. The intervention seeks to improve the appropriateness of prescribing in primary care (PC), as measured by the medication appropriateness index (MAI) score at 6 and 12months, as compared with usual care. Methods/Design: Design:pragmatic cluster randomized clinical trial. Unit of randomization: family physician (FP). Unit of analysis: patient. Scope: PC health centres in three autonomous communities: Aragon, Madrid, and Andalusia (Spain). Population: patients aged 65-74years with multimorbidity (≥3 chronic diseases) and polypharmacy (≥5 drugs prescribed in ≥3months). Sample size: n=400 (200 per study arm). Intervention: complex intervention based on the implementation of the Ariadne principles with two components: (1) FP training and (2) FP-patient interview. Outcomes: MAI score, health services use, quality of life (Euroqol 5D-5L), pharmacotherapy and adherence to treatment (Morisky-Green, Haynes-Sackett), and clinical and socio-demographic variables. Statistical analysis: primary outcome is the difference in MAI score between T0 and T1 and corresponding 95% confidence interval. Adjustment for confounding factors will be performed by multilevel analysis. All analyses will be carried out in accordance with the intention-to-treat principle. Discussion: It is essential to provide evidence concerning interventions on PC patients with polypharmacy and multimorbidity, conducted in the context of routine clinical practice, and involving young-old patients with significant potential for preventing negative health outcomes. Trial registration: Clinicaltrials.gov, NCT02866799Publisher PDFPeer reviewe

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio