1,893 research outputs found

    Extra Higgs Boson and ZZ' as Portals to Signatures of Heavy Neutrinos at the LHC

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    In this paper, we discuss the potential of observing heavy neutrino (νh\nu_h) signatures of a U(1)BLU(1)_{B-L} enlarged Standard Model (SM) encompassing three heavy Majorana neutrinos alongside the known light neutrino states at the Large Hadron Collider (LHC). We exploit the theoretical decay via a pair of heavy (non-SM-like) Higgs boson and ZZ' production followed by νhl±W()\nu_h \rightarrow l^\pm W^{\mp (*)} and νhνlZ()\nu_h \rightarrow \nu_l Z^{(*)} decays, ultimately yielding a 3l+2j+ETmiss3l+2j+E_{T}^{\rm{miss}} signature and, depending upon how boosted the final state objects are, we define different possible selections aimed at improving the signal to background ratio in LHC Run 2 data for a wide range of heavy neutrino masses.Comment: 31 pages, 10 figures. arXiv admin note: text overlap with arXiv:1612.0597

    Perceived quality of life and life style modification of cancer patients undergoing varied treatments in a tertiary health institution, Ekiti State, Nigeria

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    Introduction: cancer is viewed in the African context as a death sentence. Its effect can be overwhelming to both the patient and their support system. The objective of the study was to assess the perceived quality of life of cancer patients undergoing varied cancer treatments in a tertiary health institution in Ekiti State and to determine the life style modification of cancer patients undergoing varied treatments in the same health facility. Methods: the study employed a descriptive cross-sectional design. A consecutive sampling approach was utilized to select 80 respondents among the cancer patients who attended the cancer registry within the study time frame. Data was collected from these cancer patients by using structured and validated questionnaire. Data was analyzed using descriptive statistics and inferential statistics with level of significance set at p < 0.05. Results: respondent´s ages ranged from 20 - 61 years with a mean age of 50 ± 18.3 years. Only 7.8% are not dependent on medications to function in their daily life. Most of the participants reported that their sex life has been affected (61.1%) and 77% of the respondents reported fatigue. About 76% of respondents need varying measure of medical treatment to function in their daily life. Overall, 44.8% have poor quality of life, while 55.1% had good quality of life in this current study. Moreover, a significant relationship was found between quality of life and self-assessment of patient´s health (p < 0.001). Multivariate analysis predicting factors affecting quality of life of respondents revealed that self-assessment of respondents (AOR: 3.389; 95% CI: 1.897-6.054) remained a significant and more likely predictor of quality of life while respondent´s age (AOR: 0.244; 95% CI: 0.068-0.876) and level of education (AOR: 0.054; 95% CI: 0.005-0.546) were less likely predictors. Conclusion: one quarter of the participants have poor quality of life and majority of the participants need varying measure of medical treatment to function in their day to day life. Management of cancer patients should be geared towards improving/ameliorating symptoms and improving quality of life of cancer patients

    Parasitological identification and histological examination of Fasciola gigantica sequel to occurrence of bovine Billiary fasciolosis in cattle slaughtered at Bodija abattoir, Ibadan

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    Fasciola gigantica is the parasitic fluke causing tropical fasciolosis leading to greateconomic losses in cattle production in Nigeria. One hundred and five (105) flukes werecollected and identified after careful examination of the bile ducts from twenty one (21)infected slaughtered cattle out of a total of two hundred (200) cattle examined fromBodija Municipal Abattoir. Semichon’s Acetic-Carmine staining technique and histologicalexamination was carried out for parasitic identification while simple faecal floatation andsedimentation techniques was done for parasite egg examination. Postmortemexamination showed enlarged and friable liver covered with fibrin tags while bile ductswere thickened, distended and packed with adult flukes when sliced open. Microscopicand histological examination revealed greyish-brown leaf-shaped adult Fasciola giganticaflukes, bearing a cone shaped projection and a pair of broad shoulders with the intestinalceca branched as well as the testes and the ovary. The vitelline follicles fill the lateralfields of the worm and the common genital pore just anterior to the acetabulum. LargeFasciola gigantica eggs which are oval, yellowish to greenish in colour and bears a polaroperculum. Public enlightenment especially among the butchers and abattoir workersshould be periodical on the public health importance of the parasite and howunwholesome abattoir practices can lead to accidental human infection. This will greatlyreduce the practice of selling infected organ that have been deemed unfit for humanconsumption.Keywords: Fasciola gigantica, Cattle, Semichon’s Acetic-Carmine technique, Histology, Bile duc

    Effect of post-partum body condition score on milk yield and composition of Friesian x Bunaji dairy cows

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    The study determines the effect of dam body condition on milk yield and milk composition of dairy cows. The milk production records of 60 Friesian x Bunaji dairy cows were used for the study. The body condition score (BCS) was recorded on scale 1 to 5 with an increment of 0.25 points. The mean initial milk yield (IMY), daily milk yield (DMY) and total milk yield (TMY) was 6.54, 6.51 and 1872kg, respectively, while the mean peak yield (PY), peak day (PD), peak week (PWK) and lactation length (LL) were 10.61kg, 26.94 days, 4.33 weeks and 283.87 days, respectively. The mean fat, protein and lactose content of the milk was 4.22, 4.15 and 4.00 %, respectively, while the mean fat, protein and lactose yield was 0.269, 0.272 and 0.261 kg/day. The ratios of the milk composition were FPR (1.02), FLR (1.03) and PLR (104). There was relatively high variability in the population of the experimental animals with regard to their milk yield characteristics (CV = 15.38 – 67.13%) compared to the milk composition variables (CV = 4.36 – 26.09%). The effect of dam body condition score was significant (p<0.05) on all the milk yield  characteristics except IMY, PY and ADY. Dams with moderate BCS of between 2.5 to 3.5 during the lactation period takes longer days to peak yield (PD = 27.41 ± 3.27 days) and peak week (PWK = 4.43 ± 0.49 weeks) with longer lactation length (LL = 301 ± 31.17 days) and consequently higher TMY (1995.25 kg/lactation). However, those with higher BCS (>3.5) had higher IY (7.00 ± 1.86 kg) and shorter days to peak yield (PD = 20.50 ± 13.12 days), PWK (3.0 ± 1.95 weeks) and shorter LL (275.33 ± 25.44 days), which invariably resulted in relatively lower TMY (1819.83 ± 335.80 kg/lactation). The dam BCS had significant effect (p<0.05) on the percentage milk fat (MFC), milk lactose (MLC), fat protein ratio (FPR) and fat lactose ratio (FLR). Dams with higher (>3.5) BCS had higher MFC, MLC, FPR and FLR. It is obvious that BCS is an important factor that reflects the metabolic stability of dairy cows.Keywords: Post-partum, Body condition score, Milk yield, Milk composition, Friesian X Bunaji dairy cow

    Moringa Regimen Corrects Nicotine-induced Deficits in Behaviour, Altered Energy Metabolism and Neurotransmitter Processing in Rat Brain

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    Background: Nicotine is the addictive component of tobacco smoking. It has been reported to have a negative neuromodulatory role in the CNS. Moringa oleifera is a medicinal plant with reported antioxidant, anticonvulsant, anti-inflammatory and neuroprotective properties. Aim and Objectives: This study was purposed to investigate the neuronal adaptation potentials of Moringa Oleifera (MO) on nicotine induced behavioural decline and perturbed bioenergetics. Material and Methods: Twenty-four adult male Wistar rats were used. The treatment regimen was as follows; control group received distilled water, MO group received 200 mg/kg of MO, Nicotine Group received 1.38 mg/kg body weight of nicotine, and Nicotine + MO group received combined treatment of 200 mg/kg body weight of MO after 1.38 mg/kg body weight of nicotine for 28 days. The animals were subjected to Morris water maze for spatial memory, Y maze for working memory and elevated-plus maze tests for anxiety levels after which they were sacrificed for spectrophotometric analysis of global protein expression, neural bioenergetics (lactate dehydrogenase and glucose-6-phosphate dehydrogenase), and Acetylcholinesterase (AChE) levels. Results: Nicotine infusion caused a reduction in the escape latency period, increased the percentage incorrect alternation, and elevated the anxiety levels of rats. These observations were indicative of decreased synaptic activity in the brain. Together with, nicotine induced chromatolytic changes in cells of the frontal cortex and hippocampus. Co-administration with MO prevented nicotine-associated memory decline, perturbed glucose bioenergetics, induced chromatolysis and histomorphological distortion in the frontal cortex and hippocampus. Conclusion: Our data demonstrate that MO administration enhances experience-dependent neuroplasticity and cognitive behaviour function in laboratory animals, modulates energy metabolism and reduced oxidant stress possibly through enhanced production of key antioxidant enzymes against the damaging effects of nicotine. It provided evidence that MO can be further developed as a means to protect the brain from oxidative stress-induced injury

    Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

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    Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

    Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

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    Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis
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