22 research outputs found
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.
- Author
- Abigail Hynes
- Aditya Mandal
- Adrian Barnardo
- Aftab Ala
- Agostino Colli
- Alan Shepherd
- Alan Watson
- Alastair McNair
- Alberto Mattalia
- Alexandra McKay
- Alice Wright
- Alison Brind
- Alison Loftus
- Alison Paton
- Alistair King
- Allister Grant
- Altaf Palegwala
- Amir Shah
- Amit Singhal
- Ana Lleo
- Andrea Broad
- Andrea Crosignani
- Andrea Galli
- Andrew Austin
- Andrew Bathgate
- Andrew Bell
- Andrew Burroughs
- Andrew Chilton
- Andrew Davis
- Andrew Douds
- Andrew Douglass
- Andrew Fraser
- Andrew Gibbins
- Andrew Higham
- Andrew L Mason
- Andrzej Piotrowicz
- Andy Li
- Angelo Andriulli
- Anna Fouracres
- Annarosa Floreani
- Anne Eastick
- Anton Gunasekera
- Antonio Benedetti
- Antonio Picciotto
- Aruna Dias
- Ashis Mukhopadhya
- Ashley Brown
- Asifabbas Naqvi
- Athar Saeed
- Bal Shinder
- Barbara Coco
- Barbara Foglieni
- Barbara Hoeroldt
- Becky Holbrook
- Beverley Longhurst
- Bob Grover
- Brian D. Juran
- Bridget Bird
- Bridget Gunson
- Bronwen Williams
- Bruce R Bacon
- Caradog Thomas
- Carl A. Anderson
- Carlo Ferrari
- Carly Brown
- Carmela Cursaro
- Carol Thomas
- Carole Collins
- Carole Foale
- Caroline Cowley
- Caroline Hamilton
- Caroline Lawlor
- Caroline Mulvaney-Jones
- Caroline Palmer
- Carolyn MacNicol
- Caron Innes
- Casey S. Greene
- Catherine Gray
- Catherine Vincent
- Charles Grimley
- Charles Millson
- Chin Lye Ch'ng
- Chris Evans
- Chris Ford
- Christine Dickson
- Christopher Healey
- Christopher Hovell
- Christopher I. Amos
- Christopher Macdonald
- Christopher Shallcross
- Christopher Shorrock
- Claire Duggan
- Claudio Tiribelli
- Craig Lammert
- Cristina Barlassina
- Cynthia Levy
- D Williams
- Dakai Zhu
- Daniel Forton
- Daniele Cusi
- Daniele Prati
- Darren Clement
- David C. Qian
- David Elphick
- David Gorard
- David Jones
- David Neal
- David Ramanaden
- David Tyrer
- Dawn Sirdefield
- Deb Ghosh
- Debashis Das
- Delyth Braim
- Denise Gocher
- Denise O'Donnell
- Dermot Gleeson
- Diane Simpson
- Domenico Alvaro
- Donna Cotterill
- Douglas Thorburn
- Earl Williams
- Eileen Marshall
- Eleanor Dungca
- Elizabeth J Atkinson
- Elizabeth Tanqueray
- Elva Wilhelmsen
- Emily Archer
- Emma Durant
- Emma Grieve
- Emma Gunter
- Erik M Schlicht
- Ervin Shpuza
- Estelle Nambela
- Esther Unitt
- Fabio Macaluso
- Fabio Marra
- Faiz Ali
- Federica Malinverno
- Filomena Morisco
- Fiona Gordon
- Fiona Wright
- Floriano Rosina
- Florin Muscariu
- Frances Hines
- Francesca Bernuzzi
- Gang Xie
- Gary Bray
- Gayle Clifford
- Geeta Prasad
- George Abouda
- George Bird
- George F. Mells
- George Lipscomb
- George MacFaul
- Giancarlo Spinzi
- Gianfranco Elia
- Gideon M. Hirschfield
- Gill Watts
- Giovanni Casella
- Glynis Stansfield
- Gordon Wood
- Graeme Alexander
- Graham Butcher
- Graham Foster
- Grazia A Niro
- Gregory Whatley
- Greta Van Duyvenvoorde
- Guan Lim
- Gwen Baxter
- Hannah Dewhurst
- Harriet Gordon
- Harriet Mitchison
- Heather J. Cordell
- Helen Doyle
- Helen Fairlamb
- Helen Sweeting
- Helen Wooldridge
- Hemant Gupta
- Henry C Bodenheimer Jr
- Hilary Pateman
- Howard Curtis
- Howard Klass
- Hyder Hussaini
- Hye-Jeong Lee
- Ian Drake
- Ian Gee
- Ian Gooding
- Ian Rees
- Ilaria Bianchi
- Ilaria Sogno
- Imran Patanwala
- Imroz Salam
- Isobel Amey
- Jaber Gasem
- Jacky Orpe
- Jacqueline Brighton
- James A. B. Floyd
- James Featherstone
- James Gotto
- James Neuberger
- Jane Bowles
- Jane Collier
- Jane Gitahi
- Jane Maiden
- Jane Metcalf
- Janeane Hails
- Janette Curtis
- Janie Keggans
- Janine Musselwhite
- Javaid Subhani
- Jayne Jones
- Jean Kordula
- Jeff Butterworth
- Jennie Kendall
- Jennifer Morrison
- Jeremy Shearman
- Jeremy Tibble
- Jessica Whiteman
- Jia Qu
- Jill Conder
- Jinyi Zhang
- Jo Ridpath
- Joanna Allison
- Joanna Sayer
- Jocelyn Fraser
- John Dillon
- John Mclindon
- John Ramage
- Jonathan Booth
- Jonathan Brown
- Joseph A Odin
- Joy Sadeghian
- Joy Wilkins
- Julia Maltby
- Julie Browning
- Julie Colley
- Julie Tregonning
- Juliette Verheyden
- Kapil Kapur
- Karen Hogben
- Karen Warner
- Karin Young
- Kate Martin
- Kate Ocker
- Katharine Pollock
- Katherine A. Siminovitch
- Katherine I. Morley
- Kathryn Houghton
- Katie Seward
- Katie Spurdle
- Keith Elliott
- Keith George
- Kelly Amor
- Kerenza Boulton
- Kerry Flahive
- Kevin Yoong
- Kimberley Netherton
- Kirsten Walker
- Kirsty Martin
- Konrad Koss
- Konstantinos N. Lazaridis
- LaiTing Tan
- Landon L Chan
- Leonie Grellier
- Linda Jones
- Linda Kent
- Linda March
- Lisa Morgan
- Liz Farrington
- Lizzie Stafford
- Lola Dali-kemmery
- Lorenzo Morini
- Lorraine Hankey
- Lory Saveria Crocè
- Louise Winter
- Lourdes Cumlat
- Luca Fabris
- Lucie Hobson
- Luigi Muratori
- Lyn Graves
- Lynn Currie
- Lynn O'Donohoe
- M. Eric Gershwin
- Maggie Hughes
- Mandy Carnahan
- Marco Carbone
- Marco Marzioni
- Marek Czajkowski
- Maria Consiglia Bragazzi
- Maria Francesca Donato
- Maria Hamilton
- Maria Hayes
- Maria Vinci
- Mariam Nasseri
- Marie Green
- Marie Quinn
- Marina Leoni
- Mario Strazzabosco
- Marisa Mills
- Mariza de Andrade
- Mark Ainsworth
- Mark Aldersley
- Mark Cox
- Mark Narain
- Mark Wilkinson
- Mark Wright
- Markus Gess
- Marta Spreafico
- Martin Lombard
- Martin Prince
- Martyn Carter
- Mary Crossey
- Mary Ninkovic
- Massimo Colombo
- Massimo Zuin
- Matthew Brookes
- Matthew Cowan
- Matthew Cramp
- Matthew Foxton
- Maurizia Brunetto
- Mauro Podda
- Maxton Pitcher
- Mazn Karmo
- Mcdonald Mupudzi
- Melanie Harrison
- Melanie Kent
- Mervyn Davies
- Mesbah Rahman
- Metod Oblak
- Michael F. Seldin
- Michael Heneghan
- Mike Mendall
- Minesh Patel
- Mirko Tarocchi
- Mohamed Dawwas
- Mousa Hani S
- Natalie Taylor
- Natalie Wheatley
- Neil Fisher
- Nicholas Sharer
- Nicola Lancaster
- Nikki White
- Noma Ncube
- null null
- null null
- null null
- Nurani Sivaramakrishnan
- Oza Chirag
- Paolo Muratori
- Parizade Raymode
- Patrick Goggin
- Paul Banim
- Paul Kitchen
- Paul Richardson
- Paul Southern
- Paula Townshend
- Peter Bramley
- Peter K Gregersen
- Peter Mills
- Phillipa Desousa
- Pier Maria Battezzati
- Pierluigi Toniutto
- Piero L Almasio
- Piero Portincasa
- Pietro Andreone
- Pietro Invernizzi
- Piotr Milkiewicz
- Pradeep Sanghi
- Pranab Gyawali
- PuiChing Chan
- Purushothaman Premchand
- Rachel Abrahams
- Raj Srirajaskanthan
- Ray Mathew
- Ray Shidrawi
- Rebecca Bishop
- Rebecca Casey
- Rebecca Cloudsdale
- Rebecca Jones
- Renzo Montanari
- Reuben Ayres
- Richard Aspinall
- Richard Evans
- Richard Marley
- Richard Miller
- Richard N. Sandford
- Richard Sturgess
- Robert P Myers
- Robert Przemioslo
- Roberta Lazzari
- Roger McCorry
- Roland Ede
- Roman Galaska
- Rory Harvey
- Rosanna Fontana
- Rose Damant
- Rupert Ransford
- Ruth Penn
- Saket Singhal
- Sally Batham
- Sally-Ann Rolls
- Sallyanne Pearson
- Samantha Ducker
- Sambit Sen
- Samir Vyas
- Sandra Greer
- Sanjiv Jain
- Sarah Besley
- Sarah Jones
- Sarah Thornthwaite
- Sass Levi
- Savino Bruno
- Senayon Desmennu
- Sharat Misra
- Sherill Tripoli
- Silvia Colombo
- Simon Dyer
- Simon Panter
- Simon Rushbrook
- Simon Taylor-Robinson
- Simon Whalley
- Simon Williams
- Sonia Rossi
- Sonia Tarallo
- Sophie Holder
- Stephen D Ryder
- Steve Pereira
- Steven Mann
- Stewart Campbell
- Subramaniam Ramakrishnan
- Subrata Saha
- Sue Glenn
- Sue Walsh
- Sunil Dolwani
- Susan Congreave
- Susan Gallagher
- Susan Jones
- Susan Lord
- Susan Slininger
- Sushma Saksena
- Suzie Marriott
- Syed Shaukat
- Talal Valliani
- Theodore Ngatchu
- Thiriloganathan Mathialahan
- Tim Harding
- Tobias Balschun
- Toby Delahooke
- Tom Lee
- Tom Yapp
- Tracey Shewan
- Udi Shmueli
- Valentina Liakina
- Valeria Silvestre
- Velimir A Luketic
- Victoria Lambourne
- Vincenzo O Palmieri
- Vincenzo Ronca
- Voi Shim Wong
- William Stableforth
- Yafang Li
- Yeng Ang
- Yolanda Baird
- Younghun Han
- Publication venue
- Nat Commun
- Publication date
- 01/01/2015
- Field of study
Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
- Author
- 94
- Abigail Hynes 159
- Aditya Mandal
- Adrian Barnardo 182
- Aftab Ala 138
- Agostino Colli 45
- Alan Shepherd 213
- Alan Watson 81
- Alastair McNair 175
- Alberto Mattalia 54
- Alexandra McKay 132
- Alice Wright 245
- Alison Brind 294
- Alison Loftus 91
- Alison Paton 119
- Alistair King
- Allister Grant
- Almasio 33 Piero L.
- Altaf Palegwala 98
- Amir Shah 189
- Amit Singhal
- Amos 2 Christopher I.
- Ana Lleo 12
- Anderson 8 Carl A.
- Andrea Broad 139
- Andrea Crosignani 39
- Andrew Austin 119
- Andrew Bell 305
- Andrew Burroughs 249
- Andrew Chilton 166
- Andrew Douds 243
- Andrew Gibbins 122
- Andrew Higham 293
- Andrew Bathgate
- Andrew Davis
- Andrew Douglass
- Andrew Fraser
- Andrzej Piotrowicz
- Andy Li 303
- Angelo Andriulli 37
- Anna Fouracres 247
- Annarosa Floreani 51
- Anne Eastick
- Anton Gunasekera
- Antonio Benedetti 40
- Antonio Picciotto 59
- Aruna Dias 82
- Ashis Mukhopadhya
- Ashley Brown
- Asifabbas Naqvi
- Athar Saeed 139
- Atkinson 19 Elizabeth J.
- Bacon 28 Bruce R.
- Bal Shinder 258
- Barbara Coco 43
- Barbara Foglieni 11
- Barbara Hoeroldt 244
- Becky Holbrook 222
- Beverley Longhurst 240
- Bob Grover 151
- Bodenheimer Jr 29 Henry C.
- Bridget Bird 191
- Bridget Gunson 287
- Bronwen Williams
- Caradog Thomas
- Carlo Ferrari 49
- Carly Brown 270
- Carmela Cursaro 36
- Carol Thomas 156
- Carole Collins 300
- Carole Foale 138
- Caroline Cowley 182
- Caroline Mulvaney Jones
- Caroline Hamilton
- Caroline Lawlor
- Caroline Palmer
- Carolyn MacNicol 163
- Caron Innes
- Catherine Vincent 31
- Catherine Gray
- Chan 19 Landon L.
- Charles Grimley
- Charles Millson
- Chin Lye Ch’
- Chris Evans 190
- Chris Ford
- Christine Dickson 239
- Christopher Healey 71
- Christopher Hovell 122
- Christopher Shorrock 90
- Christopher Shallcross
- Claire Duggan 159
- Claudio Tiribelli 48
- Cordell Heather J.
- Craig Lammert 7
- Cristina Barlassina 38
- Cynthia Levy 32
- Dakai Zhu 2
- Daniel Forton 275
- Daniele Prati 11
- Daniele Cusi
- Darren Clement 294
- David Elphick 106
- David Jones 188
- David Ramanaden 86
- David Tyrer 252
- David Gorard
- David Neal
- Dawn Sirdefield
- Deb Ghosh
- Debasish Das 166
- Delyth Braim
- Denise Gocher 289
- Denise O’
- Dermot Gleeson
- Diane Simpson 239
- Domenico Alvaro 35
- Donna Cotterill 305
- Douglas Thorburn 249
- Earl Williams 246
- Eileen Marshall 249
- Eleanor Dungca 107
- Elizabeth Tanqueray 221
- Elva Wilhelmsen 165
- Emily Archer 271
- Emma Grieve 196
- Emma Gunter 246
- Emma Durant
- Eric Gershwin 15 M.
- Ervin Shpuza
- Estelle Nambela
- Esther Unitt 289
- Fabio Macaluso 34
- Faiz Ali 156
- Federica Malinverno 46
- Filomena Morisco 57
- Fiona Gordon 288
- Fiona Wright 189
- Floriano Rosina 60
- Florin Muscariu
- Floyd James A. B.
- Frances Hines
- Francesca Bernuzzi 41
- Galli Andrea
- Gang Xie
- Gary Bray 272
- Gayle Clifford 270
- Geeta Prasad 285
- George Lipscomb 91
- George MacFaul 187
- George Abouda
- George Bird
- Giancarlo Spinzi 61
- Gianfranco Elia 49
- Gill Watts 285
- Giovanni Casella 44
- Glynis Stansfield 163
- Gordon Wood 140
- Graeme Alexander 101
- Graham Foster 80
- Graham Butcher
- Greene Casey S.
- Gregersen Peter K.
- Gregory Whatley 280
- Greta Van Duyvenvoorde 90
- Guan Lim 135
- Gwen Baxter 191
- Hannah Dewhurst 246
- Harriet Gordon 145
- Harriet Mitchison 107
- Helen Doyle 109
- Helen Wooldridge 117
- Helen Fairlamb
- Helen Sweeting
- Hemant Gupta
- Hilary Pateman
- Hirschfield Gideon M.
- Howard Curtis
- Howard Klass
- Hyder Hussaini 247
- Hye Jeong Lee 167
- Ian Gooding 108
- Ian Rees 157
- Ian Drake
- Ian Gee
- Ilaria Bianchi 41
- Ilaria Sogno 41
- Imran Patanwala 252
- Imroz Salam 158
- Isobel Amey 304
- Jaber Gasem 87
- Jacky Orpe 256
- Jacqueline Brighton 138
- James Featherstone 147
- James Gotto 314
- James Neuberger 287
- Jane Bowles 318
- Jane Collier 231
- Jane Gitahi 288
- Jane Maiden 98
- Jane Metcalf
- Janeane Hails 101
- Janette Curtis 278
- Janie Keggans 191
- Janine Musselwhite
- Javaid Subhani 83
- Jayne Jones 260
- Jean Kordula
- Jeff Butterworth
- Jennie Kendall
- Jennifer Morrison 222
- Jeremy Shearman 271
- Jeremy Tibble 93
- Jessica Whiteman
- Jia Qu 25
- Jill Conder 293
- Jinyi Zhang 23
- Jo Ridpath 147
- Joanna Allison
- Joanna Sayer
- Jocelyn Fraser 304
- John Dillon 214
- John Ramage 146
- John Mclindon
- Jonathan Booth 245
- Jonathan Brown
- Joy Sadeghian 153
- Joy Wilkins 164
- Julia Maltby 253
- Julie Colley 258
- Julie Browning
- Julie Tregonning
- Juliette Verheyden
- Juran 7 Brian D.
- Kapil Kapur 79
- Karen Hogben 122
- Karen Warner
- Karin Young 196
- Kate Martin 252
- Kate Ocker 199
- Katharine Pollock
- Kathryn Houghton 188
- Katie Seward 92
- Katie Spurdle
- Keith Elliott 79
- Keith George 265
- Kelly Amor 255
- Kerenza Boulton 265
- Kerry Flahive 140
- Kevin Yoong 183
- Kimberley Netherton 283
- Kirsten Walker
- Kirsty Martin
- Konrad Koss 126
- LaiTing Tan 135
- Lazaridis 7 Konstantinos N.
- Leonie Grellier 164
- Linda Jones 245
- Linda March 238
- Linda Kent
- Lisa Morgan 302
- Liz Farrington 247
- Lizzie Stafford 231
- Lola Dali kemmery 253
- Lorenzo Morini 56
- Lorraine Hankey 122
- Lory Saveria Croce ` 48
- Louise Winter 312
- Lourdes Cumlat 306
- Luca Fabris 50
- Lucie Hobson
- Luigi Muratori 36
- Luketic 27 Velimir A.
- Lyn Graves 247
- Lynn Currie
- Lynn O’
- Maggie Hughes
- Mandy Carnahan
- Marco Carbone 101
- Marco Marzioni 40
- Marek Czajkowski
- Maria Consiglia Bragazzi 42
- Maria Francesca Donato 46
- Maria Hayes 240
- Maria Vinci 65
- Maria Hamilton
- Mariam Nasseri 151
- Marie Green 254
- Marie Quinn 303
- Marina Leoni 249
- Mario Strazzabosco
- Marisa Mills 260
- Mariza de Andrade 19
- Mark Ainsworth 231
- Mark Cox 295
- Mark Narain 159
- Mark Wright 286
- Mark Aldersley
- Mark Wilkinson
- Markus Gess 170
- Marra Fabio
- Marta Spreafico 11
- Martin Lombard 252
- Martin Prince 104
- Martyn Carter
- Mary Crossey
- Mary Ninkovic
- Mason 21 Andrew L.
- Massimo Colombo 46
- Massimo Zuin
- Matthew Brookes 254
- Matthew Cowan 279
- Matthew Cramp 238
- Matthew Foxton 105
- Maurizia Brunetto 43
- Mauro Podda 41
- Maxton Pitcher
- Mazn Karmo 109
- Mcdonald Mupudzi 286
- Melanie Harrison 70
- Melanie Kent
- Mells George F.
- Mervyn Davies
- Mesbah Rahman 68
- Metod Oblak 300
- Michael Heneghan 167
- Mike Mendall
- Minesh Patel
- Mohamed Dawwas 101
- Morley Katherine I.
- Mousa Hani S. 41
- Myers 22 Robert P.
- Natalie Taylor 265
- Natalie Wheatley 108
- Neil Fisher 123
- Nicholas Sharer 239
- Nicola Lancaster
- Nikki White
- Niro 37 Grazia A.
- Noma Ncube
- Nurani Sivaramakrishnan 186
- Odin 26 Joseph A.
- Oza Chirag
- Palmieri 58 Vincenzo O.
- Paolo Muratori 36
- Parizade Raymode 166
- Patrick Goggin 240
- Paul Banim 165
- Paul Kitchen 182
- Paul Richardson 252
- Paul Southern 92
- Paula Townshend
- Peter Bramley
- Peter Mills
- Phillipa Desousa
- Pier Maria Battezzati 39
- Pierluigi Toniutto 64
- Piero Portincasa 58
- Pietro Andreone 36
- Pietro Invernizzi
- Piotr Milkiewicz 24
- Pradeep Sanghi
- Pranab Gyawali 77
- PuiChing Chan 296
- Purushothaman Premchand 78
- Qian 2 David C.
- Rachel Abrahams 117
- Raj Srirajaskanthan 176
- Ray Shidrawi 153
- Ray Mathew
- Rebecca Bishop
- Rebecca Casey
- Rebecca Cloudsdale
- Rebecca Jones
- Renzo Montanari 55
- Reuben Ayres 248
- Richard Aspinall 240
- Richard Evans 88
- Richard Marley 80
- Richard Miller 183
- Richard Sturgess 70
- Robert Przemioslo 216 Christopher Macdonald
- Roberta Lazzari 51
- Roger McCorry 85
- Roland Ede
- Roman Galaska 71
- Rory Harvey 84
- Rosanna Fontana 37
- Rose Damant 98
- Rupert Ransford 313
- Ruth Penn
- Ryder Stephen D.
- Saket Singhal 258
- Sally Ann Rolls 156
- Sally Batham
- Sallyanne Pearson 244
- Samantha Ducker 188
- Sambit Sen 179
- Samir Vyas 257
- Sandford Richard N.
- Sandra Greer 312
- Sanjiv Jain 283
- Sarah Jones 159
- Sarah Besley
- Sarah Thornthwaite
- Sass Levi
- Savino Bruno 41
- Schlicht 7 Erik M.
- Seldin 15 Michael F.
- Senayon Desmennu
- Sharat Misra
- Sherill Tripoli
- Silvia Colombo 47
- Siminovitch Katherine A.
- Simon Panter 270
- Simon Rushbrook 215
- Simon Taylor Robinson 162
- Simon Williams 163
- Simon Dyer
- Simon Whalley
- Sonia Rossi 41
- Sonia Tarallo 60
- Sophie Holder
- Steve Pereira 284
- Steven Mann
- Stewart Campbell
- Subramaniam Ramakrishnan 296
- Subrata Saha 191
- Sue Glenn 106
- Sue Walsh 280
- Sunil Dolwani
- Susan Gallagher 294
- Susan Lord 118
- Susan Congreave
- Susan Jones
- Susan Slininger
- Sushma Saksena
- Suzie Marriott 248
- Syed Shaukat 152
- Talal Valliani 216
- Tarocchi Mirko
- Theodore Ngatchu
- Thiriloganathan Mathialahan 89
- Tim Harding
- Tobias Balschun 20
- Toby Delahooke
- Tom Yapp 69
- Tom Lee
- Tracey Shewan 279
- Udi Shmueli 221
- Valentina Liakina 30
- Valeria Silvestre 105
- Victoria Lambourne 253
- Vincenzo Ronca 41
- Voi Shim Wong 306
- William Stableforth 247
- Williams 197 D.
- Yafang Li
- Yeng Ang 312
- Yolanda Baird 304
- Younghun Han
- Publication venue
- Publication date
- 01/01/2015
- Field of study
Effects of Tityus stigmurus (Thorell 1876) (Scorpiones: Buthidae) venom in isolated perfused rat kidneys
- Author
- Abroug F
- ALICE M.C. MARTINS
- ALINE D. MARINHO
- Almeida DD
- Alves RS
- Angelo K
- ANTONIO G. SILVA NETO
- Badzyńska B
- Barona J
- Batista CV
- Berger M
- Bowman RH
- Candiano G
- Chippaux JP
- CLEIDE M.R. ALBUQUERQUE
- DALGIMAR B. MENEZES
- Dehghani R
- Duchen MR
- Faco PEG
- Fonteles MC
- Grisotto LSD
- Gwee MCE
- Harvey AL
- Heidarpour M
- HELENA S.A. MONTEIRO
- Ismail M
- Ismail M
- Jalali A
- Kusma J
- MARIA TEREZA S. CORREIA
- Martinez-Maldonado M
- Martins AMC
- Mazzei de D'Avila CA
- Mello SM
- Morais ICO
- Mosmann T
- MÁRCIA V. SILVA
- Naqvi R
- NATHALIA A. SILVA
- Nunan EA
- Ortiza E
- Possani LD
- Possani LD
- RAFAEL M. XIMENES
- RENÉ D. MARTINS
- ROBERTA J.B. JORGE
- Rodriguez de La Vega RC
- Shevchenko A
- Sitprija V
- Sitprija V
- Suntravat M
- TICIANA P. PEREIRA
- TÚLIO D. SILVA
- Valavi E
- Vasconcelos F
- Vinhote JFC
- Viswanathan S
- Walser M
- Zeghal K
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study
- Author
- Aamir Ayesha
- Abdelbadiee Sherif
- Abdullah Saad
- Abiola Oluwatosin O.
- Abras Ahmed
- Abu Emmy
- Abu-Arafeh Hashem
- Achara Amaka
- Adam Muhammad
- Adams Lawrence A. T.
- Adams Phillipa
- Aggarwal Nisha
- Ahmad Asim
- Ahmad Sarah
- Ahmed Bilquis
- Ahmed Hamza
- Ahmed Jabed
- Ahmed Rohan
- Ain Qurrat Ul
- Akintade Olugbenro
- Alareed Ahmad
- Alhadadi Baraa
- Ali Jawad
- Allain Theresa J.
- Allen James
- Alsahab Mustafa
- Amarnani Raj
- Amin Zarah
- Anderson Clementine
- Andrusca Ana
- Annamalai Arunkumar
- Ansell Matthew
- Appiah-Odame Paapa
- Arkle Thomas
- Ashton Caroline
- Astaire Emma
- Austin Keziah
- Babar Laxmi
- Babb Laura
- Bahsoon Farrah
- Baillie Jonathan
- Baldwin Jack B. G.
- Ball Katie
- Bargaoanu Imola
- Barlow Ciaran
- Baron Alexander
- Basker Karthik
- Batho Rachel
- Bazaraa Amr
- Bedi Simran
- Beeley Laura J.
- Beharry Karen
- Behbahani Abolfazl
- Behbahani Ayoub
- Bei Zhao Xiao
- Bell Charlotte
- Bertagne Marc
- Berwick L.
- Beveridge Louise
- Bhakta Shiv
- Bhat Ganapathy
- Bhattacharya Saurav
- Bhatti Jamal
- Bilton Edward
- Blair Mairi
- Bowden Helen
- Bowen Emily
- Bowman Mark A.
- Box Emma
- Bremakumar Sanojan
- Briggs Laura
- Broadhurst Karen
- Brown Harriet
- Browne Marylin
- Bryant Catherine
- Bullock Stuart
- Bultynck Celine
- Burton Jenni K.
- Bygate Rachael
- Byravan Swetha
- Caines Laurence
- Cairns Christopher
- Cameron Ewen
- Campbell Angela
- Capek Eileen
- Carter Sammy
- Cavaliere Chiara
- Chai Chung Sien
- Chamberlain Helen
- Chamboult Aimee-Louise
- Champion Jennifer
- Chapman George
- Cheah Khai L.
- Cheema Anum
- Chevolleau Jasmine
- Chilton Angharad
- Chourot Christian
- Christie Lorna
- Christodoulides Natasha
- Chuter Charlotte
- Clayton Victoria
- Cleaver Sarah L.
- Clements Hollie A.
- Coffey Farah
- Cohen Samuel
- Connell Laura
- Connor Louise
- Cook Alan
- Cooper Freya
- Cooper Olivia
- Copeland Claire
- Cox Natalie
- Cricklow Tamsin
- Croft Paul
- Crofts Jodie
- Cummings Laura
- Cunningham Emma L.
- Currie Hannah
- Cushen Claire
- Dama Sindhoora
- Darko Sandra
- Davies Rhianna
- Davies-Morris Jayne
- Davis Daniel
- De Mucha Pedro Vila
- Deacon Elizabeth
- Debrah Kwasi
- Deosaran Jordanna
- Dhillon Amber
- Doherty Cal
- Dove James
- Dovey Julie
- Drozdowska Bogna
- Durcan Rory
- Durrant Sabrina K.
- Edwards Sarah
- Einarsson Alice
- Elliott Emma
- Elliott Marianne
- Ellis Elizabeth J.
- Enfield-Bance Amy
- Evans Elizabeth
- Evans Jenny
- Evans Olivia
- Evans Sarah
- Faheem Waleed
- Fancourt Sarah
- Farah Rinata
- Faruq Sana
- Fenneley Grace
- Ferguson Eilidh E. C.
- Fergusson Niall
- Ferreira Ana Silva
- Fisken Emma
- Foster Kate
- Fraser Debbie
- Frewen John
- Furmedge Daniel
- Gallagher Michael
- Gaskell Natalie
- Gaunt Victoria
- Gaywood James
- Giblin Eleanor
- Giddings Jane
- Giet Leeying
- Giles Alexis
- Giridharan Kumudhini
- Glasser Martin
- Glasser Martin
- Gluck Ilan
- Goujon Marie
- Govindji Suriti
- Grange Robert
- Greaves Isabel
- Green Jessica
- Gregory Jemma
- Griffiths Eliza
- Grundmann Natalie
- Gui Jonathan
- Gupta Abhishek
- Gurung Sneha
- Hackett Beth
- Haddad Nedaa
- Haley Michael
- Hall Giles
- Hall Susan A.
- Handley Olivia
- Harbinson Alexander
- Harkin Teresa
- Hart Jasmine
- Hayat Yasmeen
- Headlam John
- Healy Roisin
- Henderson Neil
- Henderson Sarah
- Herbert Fiona
- Hindley Esther
- Hodhody Ghazal
- Hoffman Katrin
- Holmes Elizabeth A. M.
- Horner Sarah
- Hornsby Alex
- Horton Robbie
- Houldershaw Katie
- House Shannelle
- Hughes Clare
- Hunt Clare
- Hunt William
- Hunter Elisabeth
- Hussain Ambreen
- Hussain Zainab
- Ibanichuka Jacqueline
- Ikhwan Wan Idoracaera C.
- Ingamells Nathan
- Iqbal Shoaib
- Irvine James
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- Iwu Chioma
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- Jagdeo Sarah
- Jakupaj Adriana
- Janagal Sureena
- Jatti Puja
- Jay Emma
- Jelley Benjamin
- Jenkin Rodric
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- Jones Karen
- Jones Laura
- Jones Polly
- Kabia Angela
- Kadir Ismail
- Kalyaani Vickneswaran
- Kantczak Ada
- Katz-Summercorn Charles
- Kay Aaron
- Kearney Matthew
- Kelly Dominic
- Khalid Abdullah B.
- Khambay Ethan
- Khan Ali
- Khan Asma
- Khizar Bushra
- Khor Ming
- Kiani Mahum
- King Rachel
- Kirrane Kimberley
- Konda Nagarjun
- Koshedo Sejlo
- Krishan Anjli
- Kuek Dorothy K. C.
- Kumar Anusha
- Kumbun Gary
- Kunaselan Lleika
- Lai Jo
- Large Jamie
- Laud Rose
- Layton Georgia R.
- Le Poideven Andre
- Leah Eleanor
- Lee Helena
- Lee Tammy
- Leishman Felicity
- Lewis Anna
- Lim Su Kwan
- Lim Vee Han
- Livesey Joanna
- Lochlainn Mary Ni
- Lonsdale-Eccles Elizabeth
- Love Ryan
- Lowes Olivia
- Lucocq James E.
- Lyon Emily
- MacCuish Annabel Hentall
- Macdonald Fiona E.
- Macharouthu Ajay
- Mackenzie Eilidh R.
- Macrae Victoria
- Madden Katy F.
- Magill Laura
- Mahmood Al Wakkass
- Majid Zeinab
- Makin Stephen
- Mani Shama
- Marshall John
- Masoli Jane
- Matheswaran Yathu
- Matthews Natasha R.
- Matthews Stephanie A.
- Mayor Kara
- Mazzoleni Antonella
- McCauley Hannah
- McClean Adam
- McClelland Sarah B.
- McCluskey Heather J.
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- McCormack Roisin
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- McCulloch Alison
- McDonald Helen
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- McGonigal Gerry
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- McKeown William
- McNicholas Emily
- McQuillan Alex
- McShane David
- Menezes Reema
- Meyer Caitlin
- Miller Christopher J.
- Miller Hazel
- Millichamp Katie
- Millner Helen
- Mills Sam
- Mishra Pranav
- Mishra Rajeev
- Mitchell Oliver
- Mithrakumar Pryankaran
- Moad Mohammad
- Mohammedseid-Nurhussien Awolkhier
- Moore Emily
- Moore Kirsty
- Moorey Hannah
- Morgan Bethan
- Morgan Hannah
- Morrison Kirty
- Morrow Abbie
- Morrow Olivia
- Mosley Alice
- Mukundan Maya
- Mullarkey Emma
- Mumtaz Emma
- Murphy-Ackroyd Emily
- Murray Adam A.
- Murthy Seema
- Mustafa Zeeshan
- Naeem Fariha
- Nagumantry Shonit
- Naish George
- Nandra Taran
- Naqvi Huma
- Nashed Nader
- Ng Liji
- Ngan Esther E. Y.
- Nicholls Isabelle
- Nightingale Peter
- Nneamaka Asiodu
- Noble Jane
- Norman Emma
- Nwabufor Philip
- Nynaes Olga
- Obi Ijeoma T.
- Offer Megan
- Ofoche Gladys
- Ostrowski Caroline
- O’shea Kate
- Page Valerie
- Pailing Adam
- Pang Norman
- Parkinson Megan
- Parry Frances
- Parry Sarah
- Patel Minal D.
- Patel Riana
- Patterson Katherine
- Peck George
- Pendleton Hannah
- Perry Rita
- Pettler Sophie
- Pinkney Thomas
- Pope Leo
- Porter Lucy
- Porter-Bent Sasha
- Poynton Jack
- Prasad Vishnu
- Prendergast Emma L.
- Pullen Rosamund
- Pyc Wioletta
- Quinn Sinead
- Quinn Terrence
- Radoja Stephanie
- Rai Nisha
- Ramakrishna Sharan
- Rashid Shayan
- Rayner Helen
- Raza Mahrukh
- Reay Anna
- Reidm James
- Rice Caroline
- Richardson Sarah
- Rickard Frances
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- Robinson Hannah J.
- Robson Richard
- Ronan Lindsay
- Rose Emily C.
- Ross Anekea
- Rutter Steve
- Ryan Aidan
- Sahnan Kapil
- Saliu David
- Sami Fadi
- Sampson Elizabeth L.
- San Moe Su Su
- Sarma Dhruv
- Satharasinghe Lahiru
- Scarlett Danielle
- Scott Deborah
- Sehmbi Gurpreet
- Sen Michael
- Seymour Elaine
- Shah Hussun-Ara
- Shahid Muhammad
- Shakeel Sohail
- Shaw Megan E.
- Shepherd Alison
- Sloan Gerrard W.
- Smith Abigail
- Smith Gemma M.
- Smith Nina
- Speed James
- Sprosen Charles
- Stambollouian Katharine
- Stapley Simon M.
- Stirling Adam
- Stratton Emma
- Straughan Jacqui
- Studley Mark
- Subhan Zahid
- Sundara Srividya
- Swietoslawski Adam
- Syed Nihaad
- Tan Felicia
- Tantam Kate
- Taranu Roxana
- Taylor Abigail
- Taylor Emily
- Taylor Jemima
- Taylor Joanne
- Taylor-Rowan Martin
- Tencheva Ani
- Tetlow Simon
- Thake Miriam
- Thayabaran Darmiga
- Thomas Philip
- Thyn Thyn
- Timperley Alex
- Tinson Guy
- Todd Oliver
- Torsney Kelli
- Traill Philippa K.
- Treml Jonathan
- Tse Connie
- Tumi Ebrahiem
- Turton Sophie
- Tyagi Bhavyas
- Usmani Kasim
- Valentine Janine
- Vardon Henry
- Varghese Jessel
- Vasudev Ashish
- Vedutla Tarunya
- Velusamy Karthika
- Venkat Shabnam
- Virk Jasmine
- Visvaratnam Parrthiepan
- Wahballa Afnan
- Walker Amy
- Walter Amy
- Waraich Hana
- Warwicker Sarah
- Watson Hannah
- Watt Nicola
- Webb Hannah
- Welch Carly
- Wheeler Alice
- Whyte Lindsay
- Wilcockson James
- Wilkes Claire
- Williamson Emily
- Williamson Katherine
- Willott Ruth
- Wilson Daisy
- Wilson Daisy
- Wilson Darcy S.
- Wilson Faye
- Wilson Joseph B.
- Wilson Michael S. J.
- Winearls Stuart
- Wong Li
- Wong Ting W.
- Woodman Hannah
- Woodward Beth L.
- Wrathall Abigail
- Wright Emily
- Wright Sophie
- Wu Chenxian
- Wu Edward
- Wynne Luke
- Yap Zhi Jiun
- Young Lesley J.
- Yule Ollie
- Yunus Aayenah
- Publication venue
- Springer
- Publication date
- 01/04/2023
- Field of study
Purpose:
Delirium is a neuropsychiatric disorder delineated by an acute change in cognition, attention, and consciousness. It is common, particularly in older adults, but poorly recognised. Frailty is the accumulation of deficits conferring an increased risk of adverse outcomes. We set out to determine how severity of frailty, as measured using the CFS, affected delirium rates, and recognition in hospitalised older people in the United Kingdom.
Methods:
Adults over 65 years were included in an observational multi-centre audit across UK hospitals, two prospective rounds, and one retrospective note review. Clinical Frailty Scale (CFS), delirium status, and 30-day outcomes were recorded.
Results:
The overall prevalence of delirium was 16.3% (483). Patients with delirium were more frail than patients without delirium (median CFS 6 vs 4). The risk of delirium was greater with increasing frailty [OR 2.9 (1.8–4.6) in CFS 4 vs 1–3; OR 12.4 (6.2–24.5) in CFS 8 vs 1–3]. Higher CFS was associated with reduced recognition of delirium (OR of 0.7 (0.3–1.9) in CFS 4 compared to 0.2 (0.1–0.7) in CFS 8). These risks were both independent of age and dementia.
Conclusion:
We have demonstrated an incremental increase in risk of delirium with increasing frailty. This has important clinical implications, suggesting that frailty may provide a more nuanced measure of vulnerability to delirium and poor outcomes. However, the most frail patients are least likely to have their delirium diagnosed and there is a significant lack of research into the underlying pathophysiology of both of these common geriatric syndromes
Cytotoxic and Endocrine-Disrupting Potential of Atrazine, Diazinon, Endosulfan, and Mancozeb in Adrenocortical Steroidogenic Cells of Rainbow Trout Exposed in Vitro
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- Alice Hontela
- Babich
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- Chakravorty
- Chhabra
- Civen
- Cooper
- Corcoran
- Cranmer
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- De Blaquière
- Eldridge
- Ferrando
- Girard
- Görge
- Hamm
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- Hontela
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- Kamijima
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- Mahadevaswami
- Marjolaine Bisson
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- Pandey
- Pankhurst
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- Van Der Kraak
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- Wendelaar Bonga
- Worthing
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Carotid plaque-thickness and common carotid IMT show additive value in cardiovascular risk prediction and reclassification
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ACR Appropriateness Criteria® Acute Hip Pain-Suspected Fracture
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- 'Elsevier BV'
- Publication date
- Field of study
The War on Drugs in Afghanistan: Another Failed Experiment with Interdiction
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- Abigail R. Hall
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- James Risen
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- 'Elsevier BV'
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- 01/01/2015
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The Return of the Policy That Shall Not Be Named: Principles of Industrial Policy
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- Abramovitz Moses
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- Aghion Philippe
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- Arrow Kenneth
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- Hallward-Driemeier Mary
- Hamilton Alexander
- Harrison Ann
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- Hausmann Ricardo
- Hausmann Ricardo
- Hausmann Ricardo
- Hausmann Ricardo
- Hausmann Ricardo
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- Herrendorf Berthold
- Heum P.
- Hirschman Albert
- Hlatshwayo Sandile
- Hsieh
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- 'International Monetary Fund (IMF)'
- Publication date
- 01/01/2019
- Field of study
Elevating optimal human nutrition to a central goal of plant breeding and production of plant-based foods
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- Abbadi
- Alderman
- Alice L. Pilgeram
- Anderson
- Anstey
- Barceloux
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- Beaudoin
- Behall
- Beyer
- Blaylock
- Booth
- Bouis
- Burdge
- Cakmak
- Cavalli-Sforza
- Chakravarthy
- Cichy
- Cindy E. Morris
- Cleland
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- Cunningham-Rundles
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- David C. Sands
- De Angelisa
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- Duodu
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- Edward A. Dratz
- Falco
- Forshee
- Fradet
- Frayling
- Fuge
- Getahun
- Goldman
- Graham
- Griffiths
- Harper
- Harris
- Hauswirth
- Henneberry
- Hesser
- Hibbeln
- Hjortmo
- Hoddinnott
- Horiguchi
- Hotz
- Huang
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- Hughes
- Iglesias
- Innis
- Inouye
- Jaynes
- Jenkins
- Kagnof
- Kilberg
- Kim
- King
- Kubo
- Lamberts
- Lands
- Larsson
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- Leighton
- Levine
- Linster
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- Liou
- Lu
- Luchsinger
- Luzzatto
- Mariani-Costantini
- Meldrum
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- Mello-Neto
- Mertz
- Mickleborough
- Miflin
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- Milton
- Mohrhauer
- Montagnac
- Morant
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- Mozaffarian
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- Naqvi
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- Newell-McGloughlin
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- Oberleas
- Onyango
- Ortiz-Monasterio
- O’Keefe
- O’Kennedy
- Paine
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- Panagiotou
- Pardridge
- Pfeiffer
- Potrykus
- Ramakrishnan
- Rao
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- Rice Reyes
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- Santos
- Schoonhoven
- Scrimshaw
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- Singh
- Skrabanja
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- Sommer
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- Sugden
- Taubes
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- Tharanathan
- Tokdemir
- Ufaz
- Ursin
- van Jaarsveld
- Vasal
- Wallin
- Walsh
- Welch
- White
- Widholm
- Willemot
- Wilson
- Wilson
- Wu
- Wu
- Young
- Yu
- Zhou
- Zhu
- Zubr
- Çavdar
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study