1,875 research outputs found

    ONLINE MARKETING IN BUSINESS MURUGAPAA GROUPS CHENNAI THIRUVATUYUR

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    The new concept of Internet Marketing has immerged and is found to be dynamic in nature. Internet Marketing utilizes the power of electronic commerce which refers to any market on the internet. The internet technology has the potential to change almost every aspect of business operations.The E-Commerce portal with all its branches represents an attempt to safeguard the interest of organized users of Perambalur district and also guarding themselves against the exploitative tactics of unauthorized and hackers. The E-Commerce portal is always trying is best to maintain the dictum of all security system with quality and services under one roof. KEYWORDS: Marketing, Electronic Commerce, Internet, Marketing, Market, Technolog

    Overview of Calcitonin Gene-Related Peptide and Its Receptor

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    Calcitonin Gene-Related Peptide (CGRP), a 37 amino acid peptide identified as the alternately spliced gene product of calcitonin gene, is a sensory neuropeptide with potent cardiovascular effects. CGRP is distributed throughout the central and peripheral nervous systems and possesses diverse biological actions. CGRP has been suggested to play a role in diseases such as migraine, diabetes, pain, and inflammation. Two forms of CGRP (alpha and beta) that differ in three amino acids have been identified and are encoded by different genes. Based on the differential biological activities of various CGRP analogs, the CGRP receptors have been classified into CGRP1 and CGRP2. Structure-activity studies of CGRP analogs showed that the C- and N-terminal regions of the peptide interact independently with their receptors. While C-terminal peptide, CGRP (8-37) behaves as a CGRP1 receptor antagonist, N-terminal peptide CGRP (1-12) behaves as a weak agonist. Structural modifications of CGRP(28-37) have yielded micromolar to nanomolar affinity ligands. CGRP receptor belongs to the calcitonin receptor like receptor (CRLR) family of G-protein-coupled receptors and has been shown to require a single transmembrane domain protein called receptor activity modifying protein-1 (RAMP1) for its functional expression as well as activity. Human, rat, and porcine CRLRs have been cloned and characterized. Currently, the major focus is on the identification of potent and specific nonpeptide antagonists for this receptor in order to understand the physiological and pathophysiological role of this peptide

    Doctor of Philosophy

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    dissertationIn this dissertation, we present methods for intuitive telemanipulation of manipulators that use piezoelectric stick-slip actuators (PSSAs). Commercial micro/nano-manipulators, which utilize PSSAs to achieve high precision over a large workspace, are typically controlled by a human operator at the joint level, leading to unintuitive and time-consuming telemanipulation. Prior work has considered the use of computer-vision-feedback to close a control loop for improved performance, but computer-vision-feedback is not a viable option for many end users. We discuss how open-loop models of the micro/nano-manipulator can be used to achieve desired end-effector movements, and we explain the process of obtaining open-loop models. We propose a rate-control telemanipulation method that utilizes the obtained model, and we experimentally quantify the effectiveness of the method using a common commercial manipulator (the Kleindiek MM3A). The utility of open-loop control methods for PSSAs with a human in the loop depends directly on the accuracy of the open-loop models of the manipulator. Prior research has shown that modeling of piezoelectric actuators is not a trivial task as they are known to suffer from nonlinearities that degrade their performance. We study the effect of static (non-inertial) loads on a prismatic and a rotary PSSA, and obtain a model relating the step size of the actuator to the load. The actuator-specific parameters of the model are calibrated by taking measurements in specific configurations of the manipulator. Results comparing the obtained model to experimental data are presented. PSSAs have properties that make them desirable over traditional DC-motor actuators for use in retinal surgery. We present a telemanipulation system for retinal surgery that uses a full range of existing disposable instruments. The system uses a PSSA-based manipulator that is compact and light enough that it could reasonably be made head-mounted to passively compensate for head movements. Two mechanisms are presented that enable the system to use existing disposable actuated instruments, and an instrument adapter enables quick-change of instruments during surgery. A custom stylus for a haptic interface enables intuitive and ergonomic telemanipulation of actuated instruments. Experimental results with a force-sensitive phantom eye show that telemanipulated surgery results in reduced forces on the retina compared to manual surgery, and training with the system results in improved performance. Finally, we evaluate operator efficiency with different haptic-interface kinematics for telemanipulated retinal surgery. Surgical procedures of the retina require precise manipulation of instruments inserted through trocars in the sclera. Telemanipulated robotic systems have been developed to improve retinal surgery, but there is not a unique mapping of the motions of the surgeon's hand to the lower-dimensional motions of the instrument through the trocar. We study operator performance during a precision positioning task on a force-sensing phantom retina, reminiscent of telemanipulated retinal surgery, with three common haptic-interface kinematics implemented in software on a PHANTOM Premium 6DOF haptic interface. Results from a study with 12 human subjects show that overall performance is best with the kinematics that represent a compact and inexpensive option, and that subjects' subjective preference agrees with the objective performance results

    Intelligent routing methodology for IOT

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    There is a rapid shift to the internet of things in the fast moving world of technology and there could be billions of heterogeneous entities communicating to one another within a span of 10 years. The IOT market is still evolving initiating changes that is triggering growth in various aspects for virtualization and cloud computing. In spite of all the progress made thus far, it is tough to get into the various operational fields and complexity involved in multiple divergent areas of intercommunication. The purpose of action involving these field also vary. In this situation it will become hard to segregate and speed up communication among various entities based on priority and purpose, opening up a way for the need of a unique specifier or identifier that conveys facts about the purpose of an entity added in the IOT network based on which the message can be routed

    A performance management model for universities in Uganda

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    As far as could be established, no empirical study had been conducted with the aim of designing a performance management model for systematically managing institutional performance at public universities in Uganda. The purpose of this study therefore, was to develop an institutional performance management model for universities in Uganda. This was achieved by establishing: the extent to which public universities in Uganda implemented institutional performance management, the challenges impacting institutional performance management implementation in universities in Uganda, how public universities could ensure effective institutional performance management implementation, the various measures of institutional performance that are applicable to universities in Uganda and the key components of the institutional performance management model that could be adopted by universities in Uganda in managing institutional performance. A mixed methods approach was adopted, applying both the qualitative and quantitative methodologies. Phenomenology and cross sectional survey strategies were adopted. Interviews were conducted with purposively selected top administrators of a selected public university and the results informed the survey questionnaire. This instrument was later administered to academic staff in four public universities using a disproportionate stratified random sampling technique. The findings revealed that strategic planning in public universities in Uganda does exist and it is aimed at achieving quality. Despite the existence of strategic planning, academic staff are uncertain about a number of issues related to strategic planning. Respondents generally disagreed that: performance management training is continuously provided to managers and staff, they have an effective performance management system and a formal process exists for units to provide feedback on the attainment of goals. Among the challenges impacting performance management implementation in universities in Uganda was: (i) Lack of a formal performance management environment; (ii) Limited employee engagement/communication problems; (iii) Institutional systems and structural challenges; (iv) Institutional governance challenges. The identified factors for the successful implementation of institutional performance management were categorised into four groups namely: (i) A performance framework, performance culture and employee support; (ii) An individual performance management system; (iii) Alignment; (iv) SMART goal setting. The study established that performance measures for public universities in Uganda could be categorised into five categories namely: (i) Leadership practices, infrastructure and academic profile; (ii) Accountability; (iii) Involvement with external stakeholders; (iv) Information and knowledge transfer; (v) Strategic implementation. Finally, the proposed performance management model consisted of three phases namely: (i) Designing the strategy; (ii) Implementation of the strategy; (iii) Evaluating rewarding and improving performance. University managers should pay close attention to the identified challenges while ensuring that the factors that facilitate successful performance management implementation are in place. The measures identified by this study could be used by policy makers and universities to determine the extent of performance of the various universities, not only in Uganda but also in sub-Saharan Africa and the proposed model could be adopted by universities in Uganda as well as by all institutions of higher learning during institutional performance management implementation. Ultimately, the success of the implementation process is vested fully in the commitment and willingness of management and the employees to participate in the entire process right from the design stage to the evaluation stage

    Feedback Communication Systems with Limitations on Incremental Redundancy

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    This paper explores feedback systems using incremental redundancy (IR) with noiseless transmitter confirmation (NTC). For IR-NTC systems based on {\em finite-length} codes (with blocklength NN) and decoding attempts only at {\em certain specified decoding times}, this paper presents the asymptotic expansion achieved by random coding, provides rate-compatible sphere-packing (RCSP) performance approximations, and presents simulation results of tail-biting convolutional codes. The information-theoretic analysis shows that values of NN relatively close to the expected latency yield the same random-coding achievability expansion as with N=∞N = \infty. However, the penalty introduced in the expansion by limiting decoding times is linear in the interval between decoding times. For binary symmetric channels, the RCSP approximation provides an efficiently-computed approximation of performance that shows excellent agreement with a family of rate-compatible, tail-biting convolutional codes in the short-latency regime. For the additive white Gaussian noise channel, bounded-distance decoding simplifies the computation of the marginal RCSP approximation and produces similar results as analysis based on maximum-likelihood decoding for latencies greater than 200. The efficiency of the marginal RCSP approximation facilitates optimization of the lengths of incremental transmissions when the number of incremental transmissions is constrained to be small or the length of the incremental transmissions is constrained to be uniform after the first transmission. Finally, an RCSP-based decoding error trajectory is introduced that provides target error rates for the design of rate-compatible code families for use in feedback communication systems.Comment: 23 pages, 15 figure

    The psychological effect of orphanhood: a study of orphans in Rakai district

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    This paper examines the psychological effect of orphanhood in a case study of 193 children in Rakai district of Uganda. Studies on orphaned children have not examined the psychological impact. Adopting parents and schools have not provided the emotional support these children often need. Most adopting parents lack information on the problem and are therefore unable to offer emotional support; and school teachers do not know how to identify psychological and social problems and consequently fail to offer individual and group attention. The concept of the locus of control is used to show the relationship between the environment and individuals’ assessment of their ability to deal with it and to adjust behaviour. Most orphans risk powerful cumulative and often negative effects as a result of parents’ death, thus becoming vulnerable and predisposed to physical and psychological risks. The children were capable of distinguishing between their quality of life when their parents were alive and well, when they became sick, and when they eventually died. Most children lost hope when it became clear that their parents were sick, they also felt sad and helpless. When they were adopted, many of them felt angry and depressed. Children living with widowed fathers and those living on their own were significantly more depressed. These children were also more externally oriented than those who lived with their widowed mothers. Teachers need to be retrained in diagnosing psycho-social problems and given skills to deal with them. Short courses should be organized for guardians and community development workers in problem identification and counselling

    Bioethanol Production Using Saccharomyces cerevisae Cultivated In Sugarcorn Juice

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    For the first time, juice extracted from sugarcorn, a new Canadian energy crop, was used for bioethanol production. Physical and chemical characteristics of sugarcorn juice (SCJ) were determined. SCJ contained a maximum of 145 g/L of carbohydrates, with sucrose, glucose and fructose together contributing 80%. Effect of autoclaving and carbon filtration on juice sugars were investigated. Shake flask fermentations using Saccharomyces cerevisiae grown in yeast extract supplemented SCJ produced a maximum of 45.6 g/L ethanol in 72 h. Bioreactor studies using un-supplemented SCJ achieved 40 g/L ethanol in 26 h, yielding a maximum of 0.46 g ethanol/g fermentable sugars, representing 90.4% of theoretical yield. Sugarcorn’s crop features and juice characteristics were compared with those of sugarcane, sweet sorghum and energy cane. A proposed sugarcorn based bioethanol process was compared with corn and corn stover based processes. A Canadian sugarcorn (CANSUG) biorefinery was proposed for production of renewable fuels and chemicals

    Insitu Remediation of Mercury Contaminated Sites

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    Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv
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